Cell Biology; Cell signaling in adhesion and migration; Cell-cell and cell-matrix interactions, focus on neurons and astrocytes; cell signaling in metastasis

POST-DOCTORAL FELLOWS (Universidad de Chile)
A total of 10 Postdoctoral fellows, 6 in the last 5 years.

Ph.D. THESIS STUDENTS (total of 22 students; 10 completed since 2015; 2 in progress)
From the Ph.D. Program in Biochemistry: Ana María Avalos (2002-2006); Vicente Torres*, (2002-2006); Lorena Lobos* (2007-2011); Horacio Maldonado (2011-2015); Natalia Diaz-Valdivia* (2012-2016); Francesca Burgos (2013-2019); Esteban Palacios (2018-). From the Ph.D. Program in Biomedical Sciences: Tamara Hermosilla (2002-2005); Mónica Brito* (2005-2008); Diego Rodriguez* (2006-2009); Alejandra Valdivia (2007-2010); Rodrigo Herrera-Molina (2007-2009); Milene Kong (2010-2014); Edgardo Rojas* (2011-2015); Catalina Soto (2014); Leonardo Pérez (2017-2020); Ricardo Huilcaman* (2017-2020). From the Program in Pharmacology: Carlos Sanhueza* (2009-2013); Alvaro Alvarez (2010- 2014); Rina Ortiz, (2010-2014); Renato Burgos* (2018-). From the Program in Medical Sciences: Darío Vásquez Ph.D. (2009-2015). All from the University of Chile. *Co-adviser.
Additionally, 16 graduate students have performed lab rotations under my supervision.

POST-GRADUATE LECTURE COURSES (Chile)
Lecturer in the following Post-graduate Courses, “Cellular Signaling” (2000-2020); “Advanced Course in Integral Cellular Microscopy” (2000-2008); “Cellular Biology” (2002-2016); “Advanced Course in Cellular and Molecular Biology” (2003-2016); “Cellular Signaling Module II” (2004-2016).
Organizer and Lecturer of Post-graduate Seminar Course, “Reading and Discussing papers in English” (2004-2013); Organizer and Lecturer of Post-graduate Course, “Written and Oral Communication in Scientific English” (2010-2021); Organizer and Lecturer of Post-graduate Course, “Oral Communication Skills in Scientific English” (2014-2020); Organizer and Lecturer of Post-graduate Course, “Grammar and Written Communication skills in English” (2014-2017); Module IV in “Advanced Course in Cellular and Molecular Biology” (2006-2013); Organizer and Lecturer of Post-graduate Course, “The thesis Project” (2016-2019).

UNDERGRADUATE STUDENT TRAINING IN THE LAB
11 undergraduate thesis students; 22 undergraduate medical students, 3 Biochemistry rotation students and 1 student from abroad (Argentina).

UNDERGRADUATE TEACHING
Participation in undergraduate teaching every year
1999- 2014 Cell Biology for medical and non-medical students, Faculty of Medicine, Universidad de Chile
2000- 2001 Tutorial for medical students to develop a guidebook for “Signal Transduction” chapter of Hypercell (Garland Scientific).
2002- 2011 Tutorial to use the guidebook on signaling with various medical and non-medical students, Faculty of Medicine, University of Chile.
2007- 2008 Development of an audiovisual animation to teach programmed cell death to medical and non-medical students, Faculty of Medicine, University of Chile.
2010- 2011 Development of an interactive multimedia to teach programmed cell death to medical and non-medical students, Faculty of Medicine, University of Chile.
2013- 2014 Development of an interactive multimedia to teach Cell Signaling to medical and non-medical students, Faculty of Medicine, University of Chile

Annual participation in Explora Conicyt Project since 2003
April 2012. Entrevista programa radial FORO CIUDADANO conducido por Vicky Quevedo. Científicos chilenos estudian el sistema nervioso central. http://www.forociudadano.cl/2012/04/
June 2012, http://www.lasegunda.com/Noticias/Buena-Vida/2012/06/754730/Hallazgo-en-cerebro-permitira-reparar-dano-neuronal
July 2012,http://www.emol.com/noticias/tecnologia/2012/07/01/548542/cientificos-chilenostrabajan-
en-tratamientos-contra-traumatismos-graves.html
Sept 2012, Alumnos del colegio Antilhue de La Florida visitan laboratorio de Investigadora BNI. http://www.bni.cl/nv_detailed.php?did=285
Dec 2012, Ganadores del Mejor Trabajo sobre Neurociencia visitan laboratorios del BNI, http://noticias.uach.cl/principal.php?pag=noticia-externo&cod=55442; http://www.laaldea.cl/?p=20324
Invited editor for Special Edition in the Journal Current Molecular Medicine (published 2014) covering the two International Symposia on Cell Migration held in the Annual meeting of the Chilean Society for Cell Biology, Oct 23 – Oct 27,
2012, Puerto Varas, Chile. Leyton L, Torres VA, and Quest A.F.G. “Editorial: signaling in cell migration and disease.” Curr Mol Med. 14(2):197-8 (2014).
Symposium for the XXXII National Congress of Biochemistry Students of Chile (ANEB) and II South American Congress of Biochemistry Students, July 20– 25, 2015 (Organizer and Lecturer, Centro de Extensiones P. Universidad Católica de Chile, Santiago, Chile). Finantial support from BNI, Iniciativas Científicas Milenio.
Organizer of the visit of the International lecturer for the XXXII National Congress of Biochemistry Students of Chile (ANEB) and II South American Congress of Biochemistry Students, July 20– 25, 2015. Dr. Luis Bagatolli from the University of Denmark. Finantial support from ANEB.
Edición de la traducción al español del sitio web del "The Linus Pauling Institute Micronutrient Information Center":lpi.oregonstate.edu/mic. 2014-2015.
Invited speaker to the following symposia/conferences:
1) Faculty of Physics, Georg-August- University in Göttingen (2012) “2ndSymposium on Biophysical Methods for Medical Neurobiology -
Göttingen>
2) First NeuroSur Meeting. Pasteur Institute - Montevideo & After Hotel Montevideo, Uruguay. Symposium Cell Biology of the neuron. L. Leyton
"Bidirectional signaling between neurons and astrocytes". August 1 - 3, 2012.
3) University of North Carolina at Chapel Hill, Department of Developmental and Cellular Biology (2013). "Astrocyte adhesion and migration induced by the neuronal protein Thy-1". Invited by Dr. Keith Burridge.
4) Second NeuroSur Meeting. Leloir Institute - Buenos Aires, Argentina. NeuroSur Network. L. Leyton by A. Couve "Neurobiología Subcelular". August 29 - 30, 2013.
5) University of Lausanne, Department of Biochemistry, Friday Seminars, CIIL "Bidirectional signaling between neurons and astrocytes via Thy-1/ integrin interaction ". Invited by Dr. Pascal Schneider. University of Lausanne, Epalinges, Switzerland. September 19, 2014.
6) Third NeuroSur Meeting. Federal University of Rio de Janeiro - Rio de Janeiro, Brasil. NeuroSur Network. November 5 - 7, 2014. http://www.bni.cl/redes.php
7) School of Neurobiology (Post graduate course); From molecules to systems: Modern neurobiology at a glance. Lecturer "Regeneration and glial cells". Invited by Dr Sean Patterson, Instituto de Histología y Embriología de Mendoza (IHEM)-CONICET. Facultad de Ciencias médicas, Universidad de Cuyo, Mendoza, Argentina August 31-September 11, 2015.
8) International Symposium for the XXXIX Reunión Anual de la SBBMCh “Effect of force in Biology: from enzymes to signaling in the cell” Organized by Lisette Leyton and Christian A.M. Wilson (Universidad de Chile). Organizer and Lecturer. Centro de Convenciones Hotel Patagónico, Puerto Varas, Chile (Sept 27- 30, 2016).
9) Leyton, L. “Cell adhesion molecules in the bidirectional signaling of neurons and astrocytes” Presented in the Symposium Chile-Brasil: Neurochemistry. 45a Reunión Anual de la Sociedad Brasilera de Bioquímica y Biología Molecular Centro de Convenciones de Natal, Natal, Brasil (Junio 18-21, 2016).
10) Organization and participation in the Summer Doctoral School for young researchers from Colombia, Brazil, Peru and other Latin American countries. Activity organized by the Committee of the Doctoral Program in Biomedical Sciences and the Office of International Affairs to attract applicants to the program. 14-18 January 2019
11) News and Video about a publication in Cell Communication and Signaling. Protein interactions offer new insight into cell movement required for healing wounds, August 3, 2020. https://aqll-lab.cl/video-bytes-protein-interactions-offer-new-insight/; https://youtu.be/5VKieMZbUBM
12) News about a publication in Frontiers in Research Metrics and Analytics, section Scholarly Communication. Article written with the graduate students of an English course. September 2020 http://uchile.cl/m169957; https://cmcmed.cl/2020/11/24/; https://aqll-lab.cl/does-peer-reviewing-for-covid-19-related-papers-still-work/; https://sbcch.cl/2020/11/21/
13) Interview in radio Atractiva FM Los Lagos on Helicobacter pylori in neurodegeneration. https://www.youtube.com/watch?v=BWNWPdqUm2k; https://www.instagram.com/p/CKUqAeoHTTI/…