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Pablo Ricardo Moya Vera

Full Professor

Universidad de Valparaiso

Valparaiso, Chile

Behavioral Neuroscience Psychiatric Genetics Molecular Pharmacology

Biomedical Sciences, Universidad de Chile. Chile, 2005
Bioquimico, Universidad de Santiago de Chile. Chile, 1999

Postdoctoral Fellow Full Time

NATIONAL INSTITUTE OF HEALTH

Bethesda, Estados Unidos

2006 - 2013
Profesor Adjunto Full Time

UNIVERSIDAD DE VALPARAISO

Ciencias

Chile

2013 - 2018
Profesor Titular Full Time

UNIVERSIDAD DE VALPARAISO

Ciencias

Chile

2018 - At present

POSTDOCTORATE Full Time

NATIONAL INSTITUTE OF MENTAL HEALTH

BETHESDA, Estados Unidos

2006 - 2013
RESEARCH FELLOW Full Time

NATIONAL INSTITUTE OF HEALTH

BETHESDA, Chile

2011 - 2013

Estadías Estudiantes Internacionales
2019 Joselyn Cortes, Doctorado en Psicología, Universidad da Coruña, España
2018-2019 Nicole Steinbach, Bachillerato Biología, LMU Universität München, Alemania

Postdoc
2016-2019 Dr. José Casanova (actualmente postdoc en École Normale Supérieure, CNRS, Francia)
2018-2019 Dra. Angélica Escobar (actualmente Prof. Asistente, Universidad de Valparaíso, Chile)

PhD
2024 Valentina Haro. Doctorado en Neurociencia, Universidad de Valparaíso, Chile
2023 Francisca Henríquez. Doctorado en Neurociencia, Universidad de Valparaíso, Chile
2021 Nicolás Ardiles. Doctorado en Neurociencia, Universidad de Valparaíso, Chile
2020 Cristopher Reyes. Doctorado en Neurociencia, Universidad de Valparaíso, Chile

Magister
2019 Luis Manríquez. Magister in Neurociencias, Universidad de Valparaíso, Chile.
2019 Tito Castillo. Magister in Neurociencias, Universidad de Valparaíso, Chile.
2018 Ricardo Illesca. Magister in Neurociencias, Universidad de Valparaíso, Chile.
2017 Marisol Cisternas. Magister en Biotecnología Universidad Andrés Bello, Chile.
2017 Claudia Delgado. Magister en Ciencias Medicas, Universidad de Valparaíso, Chile.
2017 Julio Riquelme. Magister in Ciencias m/Neurología Celular, Universidad de Valparaíso, Chile.

Pregrado
2022 Francisca Marín. Bioquímica. P. Universidad Católica de Valparaíso, Chile.
2020 Mahly Villagran. Química y Farmacia, Universidad de Valparaíso, Chile.
2018 Luciana Rodriguez. Nutrición y Dietética, Universidad de Valparaíso, Chile.
2017 Francisca Henríquez. Bioquímica, P. Universidad Católica de Valparaíso, Chile.
2017 Carlos Catalán. Ingeniería Bioinformática, Universidad de Talca, Chile

Conferencias y presentaciones orales en los últimos 10 años

2023 “Impaired cognitive flexibility in a mouse model of OCD with increased forebrain expression of EAAT3”. Conference at Brain-in-Flux – MSCA NeuroTrans – ISN Joint Satellite Meeting, Aug 12-15, 2023, Porto, Portugal.
2023 “Translational approaches on the role of the excitatory amino acid transporter 3 (EAAT3) in psychiatricdisorders" Workshop “Topics in Neurochemistry: From molecules to neurons”, Graduate School P. Universidad Católica, Santiago, May 26th 2023, Chile.
2019 “OCD relevant behaviors and synaptic alterations in a mouse model with increased neuronal glutamate transporter EAAT3 expression”, Oral presentation at 4th Biennial Conference “Brain in Flux: Genetic, Physiologic, and Therapeutic Perspectives on Transporters in the Nervous System”, Saint Paulin-Quebec, Canada.
2017 “OCD Genetics: from association studies to functional studies”, Conference at the Symposium Task Force in Psychiatric Genomics, LXXII Society of Neurology and Psychiatry Meeting, Viña del Mar, Chile.
2017 “Glutamate Transporter EAAT3 as a novel target in Obsessive-Compulsive Disorder”, Seminar Series on Neuromedicine, Biomedical Neurosciences Institute BNI, Santiago, Chile.
2016 “Transgenic Mouse Overexpressing Eaat3 (Neuronal Glutamate Transporter): A Novel Genetic Model of Obsessive-Compulsive Disorder” Oral presentation at XXIV World Congress of Psychiatric Genetics, Jerusalem, Israel.
2016 “Polymorphisms in ABCB1 and ABCC2 genes in patients with Drug-Resistant Epilepsy at Van Buren Hospital in Valparaíso, Chile”. Oral presentation at the 2nd International Conference on Epilepsy and Treatment, Rome, Italy.
2014 “Common and rare gain-of-function alleles of the serotonin transporter gene, SLC6A4, associated with Tourette disorder” Oral presentation at The International Society for Serotonin Research Meeting, Arabella, South Africa.
2012 “Rare and common gain-of-function alleles of the serotonin transporter gene, SLC6A4, associated with Tourette disorder”, en sesión: “Neuropsychiatric Disorders”; 62 Annual Meeting of American Society of Human Genetics (ASHG), San Francisco, CA, USA. (Ab. # 261)
2012 “Regulación de la expresión del transportador de serotonina: variantes humanas y su rol en neuropsiquiatría”, in symposium “Neurofarmacología de transportadores de monoaminas: del modelamiento molecular a la conducta”; XXXIV reunión de la Sociedad de Farmacología de Chile, Pucón, Chile.
2012 "Functional variants in the serotonin transporter gene (SLC6A4) associated with Tourette syndrome", in nanosymposium: “ADHD, SLI, Dyslexia and Other Specific Disorders of Neurobehavior”; reunion anual de la Society for Neuroscience, New Orleans, LA, USA. (Abstract # 122.06)

Revisor

Ad-hoc: Molecular Psychiatry, Journal of Neurochemistry, Frontiers in Psychiatry, Frontiers in Pharmacology, ACS Chemical Neuroscience, Neural Plasticity, Neurochemical Research, Pharmacogenomics and Personalized Medicine.

Fondos concursables: The Austrian Science Fund FWF (2024); International OCD Foundation IOCDF (2021-present); National Agency of Research and Development ANID (formerly CONICYT) (2015-present); Chilean Fund for the Promotion of Scientific and Technological Development FONDEF (2016-present).

Difusión y prensa
https://www.savalnet.cl/mundo-medico/Noticias/avances-sobre-estudio-genomico-del-toc-en-latinoamerica.html
https://cienciaysalud.cl/2022/11/24/chile-participara-en-el-primer-estudio-genomico-de-personas-con-toc-en-latinoamerica/
https://www.litoralpress.cl/sitio/Prensa_Texto?LPKey=H2EYWS5ZNTEUYZKTZLIZPKGAXJVHDX4KD6SZN34ITXHTW6PRGSLQ
https://www.latercera.com/que-pasa/noticia/pablo-moya-del-centro-interdisciplinario-de-neurociencia-de-u-de-valparaiso-la-pandemia-ha-aumentado-sintomas-obsesivo-compulsivos-que-estaban-ocultos/5YICEAK47ZCM5PZ36X4QCXXBHE/#
https://diariotalca.cl/cuatro-universidades-investigaran-el-maltrato-infantil-en-el-maule/
https://www.tvn.cl/ntv/nochesnerd/ultimoscapitulos/noches-nerd-capitulo-8-neurociencia-4989342
https://www.cronicadigital.cl/2021/08/20/universidad-de-valparaiso-es-la-unica-institucion-de-la-v-region-autorizada-para-secuenciar-el-coronavirus-y-detectar-nuevas-variantes/
https://images.lun.com/Pages/NewsDetail.aspx?dt=2021-04-15&PaginaId=2&bodyid=0
https://www.lun.com/Pages/NewsDetail.aspx?dt=2021-03-13&PaginaId=13&bodyid=0
https://youtu.be/N6ll-oyO270
https://youtu.be/M52eOBNFma0
https://youtu.be/zowTsDfJVQY
https://youtu.be/jEG_GDqvXmk
https://www.lun.com/Pages/NewsDetail.aspx?dt=2020-07-24&PaginaId=8&bodyid=0
https://www.youtube.com/watch?v=m-XTd-iNUlw
https://www.mercuriovalpo.cl/impresa/2019/09/03/full/cuerpo-principal/8/

Fellows Award for Research Excellence (FARE),

NATIONAL INSTITUTES OF HEALTH (NIH)

Estados Unidos, 2008

NIH travel award for outstanding research projects ($1,000)
The Serotonin Club Travel Award

The Serotonin Club (now International Society for Serotonin Research)

Chile, 2004

Travel award for attendance and presentation at the Serotonin Satellite Meeting, 4th Congress of the Federation of European Pharmacological Societies (EPHAR), Porto, Portugal (£1,000 grant)
NIDA travel award

International Society for Serotonin Research

Chile, 2014

Travel Award to attend and present at the 11th International Society for Serotonin Research, Hermanus, South Africa, July 2014.


Latin American Trans-ancestry INitiative for OCD genomics (LATINO): Study protocol Crowley, James J.; Cappi, Carolina; Ochoa-Panaifo, Marcos E.; Frederick, Renee M.; Kook, Minjee; Wiese, Andrew D.; Rancourt, Diana; Atkinson, Elizabeth G.; Giusti-Rodriguez, Paola; Anderberg, Jacey L.; Abramowitz, Jonathan S.; Adorno, Victor R.; Aguirre, Cinthia; Alves, Gilberto S.; Alves, Gustavo S.; Ancalade, NaEshia; Arellano Espinosa, Alejandro A.; Arnold, Paul D.; Ayton, Daphne M.; Barbosa, Izabela G.; Castano, Laura Marcela Baron; Barrera, Cynthia N.; Berardo, Maria Celeste; Berrones, Dayan; Best, John R.; Bigdeli, Tim B.; Burton, Christie L.; Buxbaum, Joseph D.; Callahan, Jennifer L.; Carneiro, Maria Cecilia B.; Cepeda, Sandra L.; Chazelle, Evelyn; Chire, Jessica M.; Munoz, Macarena Churruca; Quiroz, Pamela Claisse; Cobite, Journa; Comer, Jonathan S.; Costa, Daniel L.; Crosbie, Jennifer; Cruz, Victor O.; Dager, Guillermo; Daza, Luisa F.; de la Rosa-Gomez, Anabel; del Rio, Daniela; Delage, Fernanda Z.; Dreher, Carolina B.; Fay, Lucila; Fazio, Tomas; Ferrao, Ygor A.; Ferreira, Gabriela M.; Figueroa, Edith G.; Fontenelle, Leonardo F.; Forero, Diego A.; Fragoso, Daniele T. H.; Gadad, Bharathi S.; Garrison, Sheldon R.; Gonzalez, Andres; Gonzalez, Laura D.; Gonzalez, Marco A.; Gonzalez-Barrios, Polaris; Goodman, Wayne K.; Grice, Dorothy E.; Guintivano, Jerry; Guttfreund, Daniel G.; Guzick, Andrew G.; Halvorsen, Matthew W.; Hovey, Joseph D.; Janssen-Aguilar, Reinhard; Jensen, Matias; Jimenez Reynolds, Alexandra Z.; Lujambio, Joali Alexandra Juarez; Khalfe, Nasim; Knutsen, Madison A.; Lack, Caleb; Lanzagorta, Nuria; Lima, Monicke O.; Longhurst, Melanie O.; Lozada Martinez, David A.; Luna, Elba S.; Marques, Andrea H.; Martinez, Molly S.; de Los Angeles Matos, Maria; Maye, Caitlyn E.; McGuire, Joseph F.; Menezes, Gabriela; Minaya, Charlene; Mino, Tomas; Mithani, Sara M.; de Oca, Circe Montes; Morales-Rivero, Alonso; Moreira-de-Oliveira, Maria E.; Morris, Olivia J.; Munoz, Sandra I.; Naqqash, Zainab; Nunez Bracho, Ambar A.; Nunez Bracho, Belinda E.; Rojas, Maria Corina Ochoa; Olavarria Castaman, Luis A.; Ortega, Iliana; Patel, Darpan I.; Patrick, Ainsley K.; Pay Y Mino, Mariel; Perales Orellana, Jose L.; Stumpf, Barbara Perdigao; Peregrina, Tamara; Duarte, Tania Perez; Piacsek, Kelly L.; Placencia, Maritza; Prieto, Maria Belen; Quarantini, Lucas C.; Quarantini-Alvim, Yana; Ramos, Renato T.; Ramos, Iaroslava C.; Ramos, Vanessa R.; Ramsey, Kesley A.; Ray, Elise V.; Richter, Margaret A.; Riemann, Bradley C.; Rivas, Juan C.; Rosario, Maria C.; Ruggero, Camilo J.; Ruiz-Chow, Angel A.; Ruiz-Velasco, Alejandra; Sagarnaga, Melisa N.; Sampaio, Aline S.; Saraiva, Leonardo C.; Schachar, Russell J.; Schneider, Sophie C.; Schweissing, Ethan J.; Seligman, Laura D.; Shavitt, Roseli G.; Soileau, Keaton J.; Stewart, S. Evelyn; Storch, Shaina B.; Strouphauer, Emily R.; Timpano, Kiara R.; Trevino-de la Garza, Beatriz; Vargas-Medrano, Javier; Vasquez, Maria I.; Martinez, Guadalupe Vidal; Weinzimmer, Saira A.; Yanez, Mauricio A.; Zai, Gwyneth; Zapata-Restrepo, Lina M.; Zappa, Luz M.; Zepeda-Burgos, Raquel M.; Zoghbi, Anthony W.; Miguel, Euripedes C.; Rodriguez, Carolyn I.; Martinez Mallen, Mayra C.; Moya, Pablo R.; Borda, Tania; Moyano, Maria Beatriz; Mattheisen, Manuel; Pereira, Stacey; Lazaro-Munoz, Gabriel; Martinez-Gonzalez, Karen G.; Pato, Michele T.; Nicolini, Humberto; Storch, Eric A.; Latin Amer Trans-Ancestry; Brazilian Obsessive-Compulsive Article ISI AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS (2023)
Protein kinase B (AKT) upregulation and Thy-1-alpha(v)beta(3) integrin-induced phosphorylation of Connexin43 by activated AKT in astrogliosis Perez-Nunez, Ramon; Chamorro, Alejandro; Fernanda Gonzalez, Maria; Contreras, Pamela; Artigas, Rocio; Corvalan, Alejandro H.; Van Zundert, Brigitte; Reyes, Christopher; Moya, Pablo R.; Avalos, Ana Maria; Schneider, Pascal; Quest, Andrew F. G.; Leyton, Lisette Article ISI JOURNAL OF NEUROINFLAMMATION (2023)
The interaction of the oxytocin receptor gene and child abuse subtypes on social cognition in euthymic patients with bipolar disorder type I Rios, Ulises; Moran, Javier; Hermosilla, Jimena; Gonzalez, Rene; Munoz, Paulina; Arancibia, Marcelo; Herrera, Luisa; Pablo Jimenez, Juan; Moya, Pablo R. Article ISI FRONTIERS IN PSYCHIATRY (2023)
Polymorphisms in schizophrenia-related genes are potential predictors of antipsychotic treatment resistance and refractoriness. Zazueta, Alejandra; Castillo T; Cavieres, A; González R.; Abarca M.; Nieto R. R.; Deneken J; Araneda, C; Moya, PR; Bustamante, ML Article WOS, ISI, Scopus INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2022)
Altered Grooming Syntax and Amphetamine-Induced Dopamine Release in EAAT3 Overexpressing Mice. Escobar, AP; Martinez-Pinto, J.; Olivares-Silva, F; Sotomayor-Zarate, R; Moya, PR Article WOS FRONTIERS IN CELLULAR NEUROSCIENCE (2021)
Oxidative stress and impaired oligodendrocyte precursor cell differentiation in neurological disorders Spaas, Jan; van Veggel, Lieve; Schepers, Melissa; Tiane, Assia; van Horssen, Jack; Wilson, David M., III; Moya, Pablo R.; Piccart, Elisabeth; Hellings, Niels; Eijnde, Bert O.; Derave, Wim; Schreiber, Rudy; Vanmierlo, Tim Article ISI CELLULAR AND MOLECULAR LIFE SCIENCES (2021)
ABC transporters and drug resistance in epilepsy: biological plausibility pharmacogenetics and precision medicine Riquelme-AlcÃ¡zar J.; GonzÃ¡lez-Vargas R.; Moya P.R. Article ISI SCOPUS REVISTA DE NEUROLOGIA (2020)
History of child abuse among patients with bipolar disorders Rios, Ulises; Moya, Pablo R.; Urrejola, Oscar; Hermosilla, Jimena; Gonzalez, Rene; Munoz, Paulina; Moran, Javier; Solervicens, Paula; Pablo Jimenez, Juan Article ISI REVISTA MEDICA DE CHILE (2020)
Ketamine-Treatment During Late Adolescence Impairs Inhibitory Synaptic Transmission in the Prefrontal Cortex and Working Memory in Adult Rats Angel Perez, Miguel; Morales, Camila; Santander, Odra; Garcia, Francisca; Gomez, Isabel; Penaloza-Sancho, Valentin; Fuentealba, Pablo; Dagnino-Subiabre, Alexies; Moya, Pablo R.; Fuenzalida, Marco Article ISI SCOPUS FRONTIERS IN CELLULAR NEUROSCIENCE (2019)
Lack of Association between the IL6R Gene Asp358Ala Variant (rs2228145), IL-6 Plasma Levels, and Treatment Resistance in Chilean Schizophrenic Patients Treated with Clozapine Cavieres, Alvaro; Campos-Estrada, Carolina; Moya, Yanneth; Maldonado, Rocio; Gonzalez-Vargas, Rene; Bustamante, Maria Leonor; Moya, Pablo R. Article WOS-ESCI SCOPUS Schizophrenia Research and Treatment (2019)
The Neuronal Glutamate Transporter EAAT3 in Obsessive-Compulsive Disorder Escobar, Angelica P.; Wendland, Jens R; Chavez, Andres E.; Moya, Pablo R. Article ISI SCOPUS FRONTIERS IN PHARMACOLOGY (2019)
3D similarities between the binding sites of monoaminergic target proteins Nunez-Vivanco, Gabriel; Fierro, Angelica; Moya, Pablo; Iturriaga-Vasquez, Patricio; Reyes-Parada, Miguel Article ISI SCOPUS PLOS ONE (2018)
Behavioral and synaptic alterations relevant to obsessive-compulsive disorder in mice with increased EAAT3 expression Delgado-Acevedo C.; Estay S.F.; Radke A.R.; Sengupta A.; Escobar A.P.; HenrÃquez-Belmar F.; Reyes C.A.; Haro-AcuÃ±a V.; Utreras E.; Sotomayor-ZÃ¡rate R.; Cho A.; Wendland J.R.; Kulkarni A.B.; Holmes A.; Murphy D.L.; ChÃ¡vez A.E.; Moya P.R. Article ISI SCOPUS NEUROPSYCHOPHARMACOLOGY (2018)
Neonatal exposure to oestradiol increases dopaminergic transmission in nucleus accumbens and morphine-induced conditioned place preference in adult female rats Bonansco, C.; Martinez-Pinto, J.; Silva, R. A.; Velasquez, V. B.; Martorell, A.; Selva, M. V.; Espinosa, P.; Moya, P. R.; Cruz, G.; Andres, M. E.; Sotomayor-Zarate, R. Article ISI SCOPUS JOURNAL OF NEUROENDOCRINOLOGY (2018)
Amphetamine treatment affects the extra-hypothalamic vasopressinergic system in a sex- and nucleus-dependent manner. Ahumada, C; Bahamondes, C; Cerda, C A; Silva, R A; Cruz, G; Moya, P R; Sotomayor-Zárate, R; Renard, G M Article Journal of neuroendocrinology (2017)
Neurochemical and behavioral characterization of neuronal glutamate transporter EAAT3 heterozygous mice González, Luis F.; Henríquez-Belmar, Francisca; Delgado-Acevedo, Claudia; Cisternas-Olmedo, Marisol; Arriagada, gloria; Sotomayor-Zárate, Ramón; Murphy, Dennis L; Moya, Pablo R Article ISI SCIELO SCOPUS Biological Research (2017)
Connecting Synaptic Activity with Plasticity-Related Gene Expression: From Molecular Mechanisms to Neurological Disorders. Muñoz, Pablo; Aschrafi, Armaz; Moya, Pablo R Article Neural plasticity (2016)
Programming of Dopaminergic Neurons by Neonatal Sex Hormone Exposure: Effects on Dopamine Content and Tyrosine Hydroxylase Expression in Adult Male Rats Espinosa, P.; Silva, RA; Sanguinetti, NK; Venegas, FC; Riquelme R.; Gonzalez, LF; Cruz, G.; Renard, GM; Moya, PR; Sotomayor-Zarate, R Article ISI SCOPUS NEURAL PLASTICITY (2016)
Improving amphetamine therapeutic selectivity: N,N-dimethyl-MTA has dopaminergic effects and does not produce aortic contraction. Sotomayor-Zárate, Ramón; Jara, Pablo; Araos, Patricio; Vinet, Raúl; Quiroz, Gabriel; Renard, Georgina M; Espinosa, Pedro; Hurtado-Guzmán, Claudio; Moya, Pablo R; Iturriaga-Vásquez, Patricio; Gysling, Katia; Reyes-Parada, Miguel Article Basic & clinical pharmacology & toxicology (2014)
Anxiety and affective disorder comorbidity related to serotonin and other neurotransmitter systems: obsessive - compulsive disorder as an example of overlapping clinical and genetic heterogeneity Murphy, Dennis L.; Moya, Pablo R.; Fox, Meredith A.; Rubenstein, Liza M.; Wendland, Jens R.; Timpano, Kiara R. Article ISI PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2013)
Common and rare alleles of the serotonin transporter gene, SLC6A4, associated with Tourette's disorder Moya, PR; Wendland, JR; Rubenstein, LM; Timpano, KR; Heiman, GA; Tischfield, JA; King, RA; Andrews, AM; Ramamoorthy, S; McMahon, FJ; Murphy, DL Article ISI SCOPUS Movement Disorders (2013)
Meta-analysis of association between obsessive-compulsive disorder and the 3 ' region of neuronal glutamate transporter gene SLC1A1 Stewart, S. E.; Mayerfeld, C.; Arnold, P. D.; Crane, J. R.; O'Dushlaine, C.; Fagerness, J. A.; Yu, D.; Scharf, J. M.; Chan, E.; Kassam, F.; Moya, P. R.; Wendland, J. R.; Delorme, R.; Richter, M. A.; Kennedy, J. L.; Veenstra-VanderWeele, J.; Samuels, J.; Greenberg, B. D.; McCracken, J. T.; Knowles, J. A.; Fyer, A. J.; Rauch, S. L.; Riddle, M. A.; Grados, M. A.; Bienvenu, O. J.; Cullen, B.; Wang, Y.; Shugart, Y. Y.; Piacentini, J.; Rasmussen, S.; Nestadt, G.; Murphy, D. L.; Jenike, M. A.; Cook, E. H.; Pauls, D. L.; Hanna, G. L.; Mathews, C. A. Article ISI AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS (2013)
miR-15a and miR-16 regulate serotonin transporter expression in human placental and rat brain raphe cells Moya, Pablo R.; Wendland, Jens R.; Salemme, Jennifer; Fried, Ruby L.; Murphy, Dennis L. Article ISI INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2013)
Mutations in monoamine oxidase (MAO) genes in mice lead to hypersensitivity to serotonin-enhancing drugs: implications for drug side effects in humans Fox, M. A.; Panessiti, M. G.; Moya, P. R.; Tolliver, T. J.; Chen, K.; Shih, J. C.; Murphy, D. L. Article ISI PHARMACOGENOMICS JOURNAL (2013)
Rare missense neuronal cadherin gene (CDH2) variants in specific obsessive-compulsive disorder and Tourette disorder phenotypes Moya, Pablo R.; Dodman, Nicholas H.; Timpano, Kiara R.; Rubenstein, Liza M.; Rana, Zaker; Fried, Ruby L.; Reichardt, Louis F.; Heiman, Gary A.; Tischfield, Jay A.; King, Robert A.; Galdzicka, Marzena; Ginns, Edward I.; Wendland, Jens R. Article ISI EUROPEAN JOURNAL OF HUMAN GENETICS (2013)
4-Methylthioamphetamine Increases Dopamine in the Rat Striatum and has Rewarding Effects In Vivo Sotomayor-Zarate, R; Quiroz, G; Araya K.A.; Abarca, J; Ibanez M.R.; Montecinos, A; Guajardo, C.; Nuñez G.; Fierro, A.; Moya, P.R.; Iturriaga-Vasquez, P; Gomez-Molina C.; Gysling, K; Reyes-Parada, M Article ISI SCOPUS Basic & clinical pharmacology & toxicology (2012)
In a Model of Batten Disease, Palmitoyl Protein Thioesterase-1 Deficiency Is Associated with Brown Adipose Tissue and Thermoregulation Abnormalities Khaibullina, Alfia; Kenyon, Nicholas; Guptill, Virginia; Quezado, Martha M.; Wang, Li; Koziol, Deloris; Wesley, Robert; Moya, Pablo R.; Zhang, Zhongjian; Saha, Arjun; Mukherjee, Anil B.; Quezado, Zenaide M. N. Article ISI PLOS ONE (2012)
A non-synonymous polymorphism in galactose mutarotase (GALM) is associated with serotonin transporter binding potential in the human thalamus: results of a genome-wide association study Liu, X.; Cannon, D. M.; Akula, N.; Moya, P. R.; Knudsen, G. M.; Arentzen, T. E.; Steele, J.; Laje, G.; Drevets, W. C.; McMahon, F. J. Article ISI MOLECULAR PSYCHIATRY (2011)
Altered 5-HT2C receptor agonist-induced responses and 5-HT2C receptor RNA editing in the amygdala of serotonin transporter knockout mice Moya, Pablo R; Fox, Meredith A; Jensen, Catherine L; Laporte, Justin L; French, Helen T; Wendland, Jens R; Murphy, Dennis L Article BMC Pharmacology (2011)
Human serotonin transporter gene (SLC6A4) variants: their contributions to understanding pharmacogenomic and other functional G x G and G x E differences in health and disease Murphy, Dennis L.; Moya, Pablo R. Article ISI CURRENT OPINION IN PHARMACOLOGY (2011)
Lentivirally mediated GSK-3 beta silencing in the hippocampal dentate gyrus induces antidepressant-like effects in stressed mice Omata, Naoto; Chiu, Chi-Tso; Moya, Pablo R.; Leng, Yan; Wang, Zhifei; Hunsberger, Joshua G.; Leeds, Peter; Chuang, De-Maw Article ISI INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2011)
Increased gene expression of diacylglycerol kinase eta in bipolar disorder Moya, Pablo R.; Murphy, Dennis L; McMahon, Francis J.; Wendland, Jens R Article ISI INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2010)
A Haplotype Containing Quantitative Trait Loci for SLC1A1 Gene Expression and Its Association With Obsessive-Compulsive Disorder Wendland, Jens R; Moya, Pablo R; Timpano, Kiara R.; Anavitarte, Adriana P.; Kruse, Matthew R.; Wheaton, Michael G.; Ren-Patterson, Renee F.; Murphy, Dennis L Article ARCHIVES OF GENERAL PSYCHIATRY (2009)
A novel, putative gain-of-function haplotype at SLC6A4 associates with obsessive-compulsive disorder Wendland, Jens R; Moya, Pablo R.; Kruse, Matthew R.; Ren-Patterson, Renee F.; Jensen, Catherine L.; Timpano, Kiara R.; Murphy, Dennis L Article ISI HUMAN MOLECULAR GENETICS (2008)
How the serotonin story is being rewritten by new gene-based discoveries principally related to SLC6A4, the serotonin transporter gene, which functions to influence all cellular serotonin systems Murphy, Dennis L; Fox, Meredith A; Timpano, Kiara R.; Moya, Pablo R.; Ren-Patterson, Renee; Andrews, Anne M.; Holmes, Andrew; Lesch, Klaus-Peter; Wendland, Jens R Article ISI NEUROPHARMACOLOGY (2008)
N,N-dimethyl-thioamphetamine and methyl-thioamphetamine, two non-neurotoxic substrates of 5-HT transporters, have scant in vitro efficacy for the induction of transporter-mediated 5-HT release and currents Gobbi, M; Funicello, M; Gerstbrein, K; Holy, M; Moya, PR; Sotomayor, R; FORRAY, MI; Gysling, K; Paluzzi, S; Bonanno G.; Reyes-Parada, M; Sitte, HH; Mennini, T Article ISI SCOPUS JOURNAL OF NEUROCHEMISTRY (2008)
Functional selectivity of hallucinogenic phenethylamine and phenylisopropylamine derivatives at human 5-hydroxytryptamine (5-HT)(2A) and 5-HT2C receptors Moya, PR; Berg, KA; Gutierrez-Hernandez, MA; Saez-Briones, P; Reyes-Parada, M; CASSELS, BK; Clarke, WP Article ISI SCOPUS JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2007)
Pharmacological identification of P2X(1), P2X(4) and P2X(7) nucleotide receptors in the smooth muscles of human umbilical cord and chorionic blood vessels Valdecantos, P; Briones, R; Moya P.; Germain A.; Huidobro-Toro, JP Article ISI SCOPUS PLACENTA (2003)
Differences in potency and efficacy of a series of phenylisopropylamine/phenylethylamine pairs at 5-HT2A and 5-HT2C receptors Acuna-Castillo, C; Villalobos C.; Moya, PR; Saez P.; CASSELS, BK; Huidobro-Toro, J Article ISI BRITISH JOURNAL OF PHARMACOLOGY (2002)


Evaluación de la efectividad de una intervención psicoeducativa para el manejo del estrés sobre los niveles de cortisol, ansiedad y rendimiento académico en alumnos de la Aacademia Politécnica Naval Moya, Pablo R. Proyecto (2023)
The role of the excitatory amino acid transporter EAAT3 in depressive behavior induced by chronic stress Moya, Pablo Ricardo; Chávez, Andrés E.; Sotomayor-Zárate, Ramón Proyecto (2023)
Endocannabinoid modulation of specific inhibitory circuits that regulate cortical function Chiu, Chiayu; Moya, Pablo Ricardo Proyecto (2022)
One Health Network: Dengue and Emerging Medically Important Arboviruses (DEMIV‐OH) Collao, Ximena; Moya, Pablo R; Salas, Rodrigo J. Proyecto (2022)
Molecular and Functional Evaluation of a Mouse Model of Obsessive-Compulsive Disorder with Increased EAAT3 Expression Pablo Moya; Andrés Chávez; Rómulo Fuentes Proyecto (2019)
Centro Interdisciplinario de Neurociencia de Valparaíso CINV Iniciativa Científica Milenio (P09-022-F) Proyecto 2017-2020 Investigador(a)
EVALUACIÓN DE BIOMARCADORES GENÉTICOS EN PACIENTES CON EPILEPSIA RESISTENTE A FÁRMACOS DEL POLICLÍNICO DE NEUROLOGÍA DEL HOSPITAL CARLOS VAN BUREN FONIS (SA16I0003) Proyecto 2017-2018 Director(a)
NEONATAL PROGRAMMING=> SEX HORMONES EXCESS DISRUPTS MIDBRAIN DOPAMINE FUNCTION IN THE ADULTHOOD. FONDECYT (1160398) Proyecto 2016-2020 Coinvestigador(a)
GENERATION AND FUNCTIONAL CHARACTERIZATION OF MICE WITH ALTERED EXPRESSION OF EAAT3=>A MODEL FOR OBSESSIVE-COMPULSIVE DISORDER. FONDECYT (1141272) Proyecto 2014-2018 Inv. Responsable
Nucleo Milenio en Biologia de Enfermedades Neuropsiquiátricas NU-MIND Iniciativa Cientifica Milenio - Ministerio de Economia (NC130011) Proyecto 2014-2017 Inv. Principal
PAPEL DE CANALES DE CALCIO EN EL ESTABLECIMIENTO DEL PATRON DORSOVENTRAL EN EL EMBRION DE XENOPUS LAEVIS. FONDECYT (1040829) Proyecto 2004-2007 Personal técnico y/o de apoyo


Implications of Physical Exercise on Episodic Memory and Anxiety: The Role of the Serotonergic System Illesca-Matus, Ricardo; Ardiles, Nicolas M.; Munoz, Felipe; Moya, Pablo R. Review ISI INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2023)

Pablo Moya

Full Professor

Instituto de Fisiología

Universidad de Valparaiso

Valparaiso, Chile

Ramón Sotomayor

Full Professor

Institute of Physiology

UNIVERSIDAD DE VALPARAÍSO, FACULTAD DE CIENCIAS, DEPARTAMENTO DE FISIOLOGÍA

Valparaíso, Chile

Miguel Reyes

Full Professor

Facultad de Ciencias Médicas

UNIVERSIDAD DE SANTIAGO DE CHILE, FACULTAD DE CIENCIAS MÉDICAS, ESCUELA DE MEDICINA

Santiago, Chile

Katia Gysling

Professor

Cellular and Molecular Biology

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Andres Chavez

Full Professor

Neuroscience

Universidad de Valparaiso

Valparaiso, Chile

Alvaro Cavieres

Profesor

Departamento de Psiquiatría

Universidad de Valparaíso

Valparaíso, Chile

Andrew Quest

Full Professor

Biologia Celular y Molecular

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

Marcelo Arancibia

Principal investigator

Universidad de Valparaíso

Viña del Mar, Chile

Lisette Leyton

Full Professor

Cell and Molecular Biology

FACULTAD DE MEDICINA UNIVERSIDAD DE CHILE

Santiago, Chile

VICTORIA VELASQUEZ

PhD student

Fisiología

Universidad de Valparaíso

Valparaíso, Chile

Oscar Urrejola

Subdirector de Investigación

Dirección Médica Nacional

Teletón

Santiago, Chile

Alexies Dagnino

Full Professor

Physiology

UNIVERSIDAD DE VALPARAÍSO

Valparaíso, Chile

Maria Bustamante

Profesora Asistente

Facultad de Medicina

Universidad de Chile

Santiago , Chile

Carolina Campos

Associate Professor

School of Chemistry and Pharmacy

Universidad de Valparaiso

Valparaíso, Chile

Marco Fuenzalida

Full Professor

Physiology

UNIVERSIDAD DE VALPARAÍSO

Valparaíso, Chile

Pablo Fuentealba

Assistant Professor

Psychiatry

Pontificia Universidad Catolica de Chile

Santiago, Chile

MIGUEL PEREZ

Associate Professor

Pontificia Universidad Catolica de Valparaiso

VALPARAISO, Chile

Gabriel Quiroz

Angelica Fierro

Associate

Chemistry

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Patricio Iturriaga

Profesor Asociado A

Ciencias Quimicas y Recursos Naturales

UNIVERSIDAD DE LA FRONTERA

Temuco, Chile

Pablo Moya

Docente de apoyo

Kinesiología

Universidad de

Santiago, Chile

Jonathan Martínez

Profesor ayudante

UNIVERSIDAD DE VALPARAISO

Valparasiso, Chile

María Andrés

Full Professor

Cellular and Molecular Biology

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

DOMINGO BONANSCO

Profesor Titular

Instituto de Fisiologia

UNIVERSIDAD DE VALPARAISO, FACULTAD DE CIENCIAS

Valparaiso, Chile

Gabriel Nuñez

Jefe de Carrera, Ingeniería Civil Informática

Ciencias Naturales y Tecnología

Universidad de Aysén

Coyhaique, Chile

Gloria Arriagada

Profesor Asociado-Investigador Principal

Instituto de Ciencias Biomédicas

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

Claudio Acuña

Profesosr Asociado

Biología

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

Maria Forray

PROFESOR ASOCIADO

FARMACIA

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

SANTIAGO, Chile

Gonzalo Cruz

UNIVERSIDAD DE VALPARAISO

VALPARAISO, Chile

Marisol Cisternas

PHD c

Universidad Mayor de Chile

Santiago, Chile

Julio Riquelme

MÉDICO NEURÓLOGO

SERVICIO NEUROLOGÍA

HOSPITAL CARLOS VAN BUREN

Valparaíso, Chile

Maria Ibañez

DIRECTORA GENERAL DE INVESTIGACIÓN E INNOVACIÓN

UNIVERSIDAD DEL ALBA

Santiago, Chile

Angélica Escobar

Profesora Auxiliar

Fisiología

valp

Valparaiso, Chile

Pablo Ricardo Moya Vera

Líneas de Investigación

Educación

Biomedical Sciences, Universidad de Chile. Chile, 2005

Bioquimico, Universidad de Santiago de Chile. Chile, 1999

Experiencia Académica

Postdoctoral Fellow Full Time

Profesor Adjunto Full Time

Profesor Titular Full Time

Experiencia Profesional

POSTDOCTORATE Full Time

RESEARCH FELLOW Full Time

Formación de Capital Humano

Difusión y Transferencia

Premios y Distinciones

Fellows Award for Research Excellence (FARE),

The Serotonin Club Travel Award

NIDA travel award

Article (39)

Proyecto (11)

Centro Interdisciplinario de Neurociencia de Valparaíso CINV

EVALUACIÓN DE BIOMARCADORES GENÉTICOS EN PACIENTES CON EPILEPSIA RESISTENTE A FÁRMACOS DEL POLICLÍNICO DE NEUROLOGÍA DEL HOSPITAL CARLOS VAN BUREN

NEONATAL PROGRAMMING=> SEX HORMONES EXCESS DISRUPTS MIDBRAIN DOPAMINE FUNCTION IN THE ADULTHOOD.

GENERATION AND FUNCTIONAL CHARACTERIZATION OF MICE WITH ALTERED EXPRESSION OF EAAT3=>A MODEL FOR OBSESSIVE-COMPULSIVE DISORDER.

Nucleo Milenio en Biologia de Enfermedades Neuropsiquiátricas NU-MIND

PAPEL DE CANALES DE CALCIO EN EL ESTABLECIMIENTO DEL PATRON DORSOVENTRAL EN EL EMBRION DE XENOPUS LAEVIS.

Review (1)