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Angélica Del Pilar Escobar Maldonado

Profesora Auxiliar

valp

Valparaiso, Chile

-Rol de la disminución crónica de DA sobre la inducción de conductas compulsivas en un modelo de sensibilización a quinpirol. -Impacto de la sobreexpresión del transportador de glutamato EAAT3 sobre el sistema dopaminérgico y compulsión

Doctora en Ciencias Biológicas mención Biología Celular y Molecular, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2016
Químico Farmaceutico, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2010

Profesora Auxiliar Full Time

UNIVERSIDAD DE VALPARAISO

Ciencias

Valparaiso, Chile

2020 - At present

Profesora honorarios Part Time

Universidad del pacifico

Santiago, Chile

2016 - 2016
Químico Farmacéutico Full Time

Cesfam Teniente Julio Allende

Ninhue, Chile

2016 - 2017


Central and Peripheral Inflammation: A Common Factor Causing Addictive and Neurological Disorders and Aging-Related Pathologies Escobar, Angelica P.; Bonansco, Christian; Cruz, Gonzalo; Dagnino-Subiabre, Alexies; Fuenzalida, Marco; Negron, Ignacio; Sotomayor-Zarate, Ramon; Martinez-Pinto, Jonathan; Jorquera, Gonzalo Article ISI INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2023)
Effects of Early Life Exposure to Sex Hormones on Neurochemical and Behavioral Responses to Psychostimulants in Adulthood: Implications in Drug Addiction Elgueta-Reyes, Maximiliano; Velasquez, Victoria B.; Espinosa, Pedro; Riquelme, Raul; Dib, Tatiana; Sanguinetti, Nicole K.; Escobar, Angelica P.; Martinez-Pinto, Jonathan; Renard, Georgina M.; Sotomayor-Zarate, Ramon Article ISI INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)
Immunolocalization of kappa opioid receptors in the axon initial segment of a group of embryonic mesencephalic dopamine neurons Pilar Escobar, Angelica; Meza, Rodrigo C.; Gonzalez, Marcela; Henny, Pablo; Andres, Maria Estela Article ISI IBRO NEUROSCIENCE REPORTS (2022)
Altered Grooming Syntax and Amphetamine-Induced Dopamine Release in EAAT3 Overexpressing Mice Escobar, Angelica P.; Martinez-Pinto, Jonathan; Silva-Olivares, Francisco; Sotomayor-Zarate, Ramon; Moya, Pablo R. Article ISI FRONTIERS IN CELLULAR NEUROSCIENCE (2021)
Knockout or Knock-in? A Truncated D2 Receptor Protein Is Expressed in the Brain of Functional D2 Receptor Knockout Mice Sanchez, Natalia; Olivares-Costa, Montserrat; Gonzalez, Marcela P.; Munita, Roberto; ESCOBAR-MALDONADO, ANGELICA DEL PILAR; Meza, Rodrigo C.; Herrera-Rojas, Mauricio; Albornoz, Jessica; Merello, Gianluca; ANDRES-COKE, MARIA ESTELA Article ISI (2021)
Study of the release of endogenous amines in Drosophila brain in vivo in response to stimuli linked to aversive olfactory conditioning Hidalgo, Sergio; Fuenzalida-Uribe, Nicolas; Molina-Mateo, Daniela; Escobar, Angelica P.; Oliva, Carlos; Espana, Rodrigo A.; Estela Andres, Maria; Campusano, Jorge M. Article ISI JOURNAL OF NEUROCHEMISTRY (2021)
The Neuronal Glutamate Transporter EAAT3 in Obsessive-Compulsive Disorder Escobar, Angelica P.; Wendland, Jens R; Chavez, Andres E.; Moya, Pablo R. Article ISI SCOPUS FRONTIERS IN PHARMACOLOGY (2019)
Mechanisms of kappa opioid receptor potentiation of dopamine D2 receptor function in quinpirole-induced locomotor sensitization in rats. Escobar AP, Gonzalez MP; Meza RC, Noches V; Henny P, Gysling K; España RA, Fuentealba JA Article the international journal of neuropsychopharmacology (2017)
The Role of Kappa Opioid Receptors in Glutamate Input Selection in the Ventral Striatum. Article JOURNAL OF NEUROSCIENCE (2017)
Reduced dopamine and glutamate neurotransmission in the nucleus accumbens of quinpirole-sensitized rats hints at inhibitory D2 autoreceptor function. Escobar A.P., Cornejo F.A.; Olivares-Costa M., González M.; Fuentealba J.A., Gysling K.; España R.A., Andrés M.E. Article Journal of Neurochemistry (2014)
Repeated treatment with the kappa opioid receptor agonist U69593 reverses enhanced K+ induced dopamine release in the nucleus accumbens, but not the expression of locomotor sensitization in amphetamine-sensitized rats. Adel P. Escobar, Cornejo F.A.; Andres M.E., Fuentealba J.A. Article Neurochemistry international (2012)


Behavioral and synaptic alterations relevant to obsessivecompulsive disorder in mice with increased EAAT3 expression (vol 46, pg 1163, 2019) Delgado-Acevedo C.; Estay S.F.; Radke A.K.; Sengupta A.; Escobar A.P.; HenrÃquez-Belmar F.; Reyes C.A.; Haro-AcuÃ±a V.; Utreras E.; Sotomayor-ZÃ¡rate R.; Cho A.; Wendland J.R.; Kulkarni A.B.; Holmes A.; Murphy D.L.; ChÃ¡vez A.E.; Moya P.R. Errata ISI SCOPUS NEUROPSYCHOPHARMACOLOGY (2019)


Impact of dopamine levels and D2 receptors on the induction and treatment of compulsive behaviors Escobar Maldonado, Angelica Proyecto (2024)
Restoring Parvalbumin Interneuron Function reverts long-lasting consequences of adolescent ketamine exposure on dentante gyrus function and recognition memories Fuenzalida, Marco Proyecto (2024)
Role of GLP-1/GLP-1 Receptor system of lateral septum in obesity and food addiction Sotomayor-zarate, Ramon Proyecto (2024)
Núcleo Milenio de Neuroepigenética y Plasticidad EPI-NEURO Van Zundert, Brigitte Proyecto (2023)
Impact of the overexpression of the neuronal glutamate transporter EAAT3 on dopamine system Escobar Maldonado, Angelica Proyecto (2019)
centro interdisciplinario de neurociencia de Valparaiso Iniciativa cientifica milenio (00102) Proyecto 2017-2032 Postdoctorado
MOLECULAR AND NEUROCHEMICAL DYSFUNCTIONS IN AN ANIMAL MODEL OF OBSESSIVE-COMPULSIVE DISORDER FONDECYT (1110352) Proyecto 2011-2015 Tesista
Núcleo Milenio en Estrés y Adicción (NEDA) Iniciativa científica milenio (MSI P10/063F) Proyecto 2008-2014 Personal técnico y/o de apoyo
STUDY OF THE NEURONAL ACTIVITY OF THE RAT MEDIAL PREFRONTAL CORTEX AFTER REPEATED TREATMENT WITH AMPHETAMINE. FONDECYT (11075068) Proyecto 2007-2010 Tesista


Long-Range GABAergic Projections of Cortical Origin in Brain Function Urrutia-Pinones, Jocelyn; Morales-Moraga, Camila; Sanguinetti-Gonzalez, Nicole; Escobar, Angelica P.; Chiu, Chiayu Q. Review ISI FRONTIERS IN SYSTEMS NEUROSCIENCE (2022)