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Angélica Del Pilar Escobar Maldonado

Profesora Auxiliar

valp

Valparaiso, Chile

Líneas de Investigación


-Rol de la disminución crónica de DA sobre la inducción de conductas compulsivas en un modelo de sensibilización a quinpirol. -Impacto de la sobreexpresión del transportador de glutamato EAAT3 sobre el sistema dopaminérgico y compulsión

Educación

  •  Doctora en Ciencias Biológicas mención Biología Celular y Molecular, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2016
  •  Químico Farmaceutico, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2010

Experiencia Académica

  •   Profesora Auxiliar Full Time

    UNIVERSIDAD DE VALPARAISO

    Ciencias

    Valparaiso, Chile

    2020 - At present

Experiencia Profesional

  •   Profesora honorarios Part Time

    Universidad del pacifico

    Santiago, Chile

    2016 - 2016

  •   Químico Farmacéutico Full Time

    Cesfam Teniente Julio Allende

    Ninhue, Chile

    2016 - 2017


 

Article (11)

Central and Peripheral Inflammation: A Common Factor Causing Addictive and Neurological Disorders and Aging-Related Pathologies
Effects of Early Life Exposure to Sex Hormones on Neurochemical and Behavioral Responses to Psychostimulants in Adulthood: Implications in Drug Addiction
Immunolocalization of kappa opioid receptors in the axon initial segment of a group of embryonic mesencephalic dopamine neurons
Altered Grooming Syntax and Amphetamine-Induced Dopamine Release in EAAT3 Overexpressing Mice
Knockout or Knock-in? A Truncated D2 Receptor Protein Is Expressed in the Brain of Functional D2 Receptor Knockout Mice
Study of the release of endogenous amines in Drosophila brain in vivo in response to stimuli linked to aversive olfactory conditioning
The Neuronal Glutamate Transporter EAAT3 in Obsessive-Compulsive Disorder
Mechanisms of kappa opioid receptor potentiation of dopamine D2 receptor function in quinpirole-induced locomotor sensitization in rats.
The Role of Kappa Opioid Receptors in Glutamate Input Selection in the Ventral Striatum.
Reduced dopamine and glutamate neurotransmission in the nucleus accumbens of quinpirole-sensitized rats hints at inhibitory D2 autoreceptor function.
Repeated treatment with the kappa opioid receptor agonist U69593 reverses enhanced K+ induced dopamine release in the nucleus accumbens, but not the expression of locomotor sensitization in amphetamine-sensitized rats.

Errata (1)

Behavioral and synaptic alterations relevant to obsessivecompulsive disorder in mice with increased EAAT3 expression (vol 46, pg 1163, 2019)

Proyecto (9)

Impact of dopamine levels and D2 receptors on the induction and treatment of compulsive behaviors
Restoring Parvalbumin Interneuron Function reverts long-lasting consequences of adolescent ketamine exposure on dentante gyrus function and recognition memories
Role of GLP-1/GLP-1 Receptor system of lateral septum in obesity and food addiction
Núcleo Milenio de Neuroepigenética y Plasticidad EPI-NEURO
Impact of the overexpression of the neuronal glutamate transporter EAAT3 on dopamine system
centro interdisciplinario de neurociencia de Valparaiso
MOLECULAR AND NEUROCHEMICAL DYSFUNCTIONS IN AN ANIMAL MODEL OF OBSESSIVE-COMPULSIVE DISORDER
Núcleo Milenio en Estrés y Adicción (NEDA)
STUDY OF THE NEURONAL ACTIVITY OF THE RAT MEDIAL PREFRONTAL CORTEX AFTER REPEATED TREATMENT WITH AMPHETAMINE.

Review (1)

Long-Range GABAergic Projections of Cortical Origin in Brain Function
14
Angélica Escobar

Profesora Auxiliar

Fisiología

valp

Valparaiso, Chile

3
Ramón Sotomayor

Full Professor

Institute of Physiology

UNIVERSIDAD DE VALPARAÍSO, FACULTAD DE CIENCIAS, DEPARTAMENTO DE FISIOLOGÍA

Valparaíso, Chile

2
María Andrés

Full Professor

Cellular and Molecular Biology

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
VICTORIA VELASQUEZ

PhD student

Fisiología

Universidad de Valparaíso

Valparaíso, Chile

1
Alexies Dagnino

Full Professor

Physiology

UNIVERSIDAD DE VALPARAÍSO

Valparaíso, Chile

1
Andres Chavez

Full Professor

Neuroscience

Universidad de Valparaiso

Valparaiso, Chile

1
Pablo Moya

Full Professor

Instituto de Fisiología

Universidad de Valparaiso

Valparaiso, Chile

1
Carlos Oliva

Profesor Asociado

Biología Celular y Molecular

Pontificia Universidad Católica de Chile

Santiago, Chile