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PATRICIA ALEJANDRA CARVAJAL GARCES

Investigadora Postdoctoral

Universidad de Chile

Santiago, Chile

Ciencias Biomédicas, UNIVERSIDAD DE CHILE. Chile, 2022
Biomedicina Celular y Molecular, UNIVERSIDAD DE CHILE. Chile, 2017
Biotecnóloga, UNIVERSIDAD DE ANTOFAGASTA. Chile, 2014


Integrated stress response inhibition restores hsa-miR-145-5p levels after IFN-β stimulation in salivary gland epithelial cells. Association between cellular stress and miRNA biogenesis in Sjogren's disease Castro, Isabel; Carvajal, Patricia; Aguilera, Sergio; Barrera, Maria-Jose; Matus, Soledad; Gonzalez, Sergio; Molina, Claudio; Gonzalez, Maria-Julieta Article ISI JOURNAL OF AUTOIMMUNITY (2025)
Giantin mediates Golgi localization of Gal3-O-sulfotransferases and affects salivary mucin sulfation in patients with Sjogren's disease Nunez, Matilde; Carvajal, Patricia; Aguilera, Sergio; Barrera, Maria-Jose; Matus, Soledad; Couto, Alicia; Landoni, Malena; Boncompain, Gaelle; Gonzalez, Sergio; Molina, Claudio; et al. Article ISI JCI INSIGHT (2024)
hsa-miR-424-5p and hsa-miR-513c-3p dysregulation mediated by IFN-? is associated with salivary gland dysfunction in Sjogren's syndrome patients Jara, Daniela; Hermoso, Marcela Article ISI JOURNAL OF AUTOIMMUNITY (2023)
The integrated stress response is activated in the salivary glands of Sjogren's syndrome patients Bahamondes, Veronica; Jara, Daniela; Matus, Soledad; Hermoso, Marcela Article ISI FRONTIERS IN MEDICINE (2023)
Small RNA Expression Profiling Reveals hsa-miR-181d-5p Downregulation Associated With TNF-alpha Overexpression in Sjogren's Syndrome Patients Jara, Daniela; Hermoso, Marcela Article ISI FRONTIERS IN IMMUNOLOGY (2022)
Saliva sample for the massive screening of SARS-CoV-2 infection: a systematic review Canete, Martin Gonzalez; Valenzuela, Isidora Mujica; Garces, Patricia Carvajal; Masso, Isabel Castro Article ISI ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY (2021)
Tofacitinib counteracts IL-6 overexpression induced by deficient autophagy: implications in Sjogren's syndrome Matus, Soledad; Jara, Daniela Article ISI RHEUMATOLOGY (2021)
Type I Interferon Dependent hsa-miR-145-5p Downregulation Modulates MUC1 and TLR4 Overexpression in Salivary Glands From Sjogren's Syndrome Patients Jara, Daniela Article ISI FRONTIERS IN IMMUNOLOGY (2021)
Aberrant MUC1 accumulation in salivary glands of Sjögren's syndrome patients is reversed by TUDCA in vitro. Castro I, Albornoz N, Aguilera S, Barrera MJ, González S, Núñez M, Carvajal P, Jara D, Lagos C, Molina C, Urzúa U, Hermoso MA, González MJ. Article ISI SCOPUS Rheumatology (Oxford, England) (2020)
Synaptotagmin-1 overexpression under inflammatory conditions affects secretion in salivary glands from Sjogren's syndrome patients Article ISI SCOPUS JOURNAL OF AUTOIMMUNITY (2019)
Association of high 5-hydroxymethylcytosine levels with Ten Eleven Translocation 2 overexpression and inflammation in Sjögren's syndrome patients Lagos, Carolina; Jara, Daniela; Leyton, Cecilia Article ISI SCOPUS Clinical Immunology (2018)
Endoplasmic reticulum stress in autoimmune diseases: Can altered protein quality control and/or unfolded protein response contribute to autoimmunity? A critical review on Sjogrens syndrome Article ISI SCOPUS AUTOIMMUNITY REVIEWS (2018)
Impaired IRE1 alpha/XBP-1 pathway associated to DNA methylation might contribute to salivary gland dysfunction in Sjogrens syndrome patients Sepulveda, Denisse; Castro, Isabel; Aguilera, Sergio; Carvajal, Patricia; Lagos, Carolina; Albornoz, Nicolás; Quest, Andrew F. G.; Molina, Claudio; Leyton, Cecilia; Hermoso, Marcela A. Article ISI SCOPUS RHEUMATOLOGY (2018)


Altered Expression of the MicroRNA Biogenesis Machinery Components Correlates with Inflammatory Parameters in Salivary Glands of Patient with Sjogren's Disease Aguilera, S; Carvajal, P; Castro, I; Barrera, MJ; Gonz lez, S; Molina C.; Gonz lez, MJ Abstract ISI (2024)


MUC1-C induce la expresión de genes relacionados a interferones en glándulas salivales de pacientes con síndrome de Sjögren y la inhibición de MUC1-C disminuye la inflamación Patricia Carvajal Garces Proyecto (2024)
Cytokines induce alterations in stress response pathways of the endoplasmic reticulum in salivary glands of Sjögren's syndrome patients=> Can these modulated by epigenetic mechanisms? FONDECYT (1160015) Proyecto 2016-2019 Tesista
Centro de Biotecnología y Bioingeniería (CeBiB) PIA (FB0001) Proyecto 2014-2018 Personal técnico y/o de apoyo
Analysis of the epigenetic regulation in the ribosomal cistron induced by environmental stimuli in Cyprinus carpio fish. FONDECYT (1120873) Proyecto 2012-2014 Tesista


Dysfunctional mitochondria as critical players in the inflammation of autoimmune diseases: Potential role in Sjo¨gren's syndrome Jara, Daniela Review ISI AUTOIMMUNITY REVIEWS (2021)

5

Maria González

Academico

FACULTAD DE MEDICINA - UNIVERSIDAD DE CHILE

Santiago, Chile

5

Marcela Hermoso

Full Professor

School of Medicine

UNIVERSIDAD DE CHILE

Santiago, Chile

2

Andrew Quest

Full Professor

Biologia Celular y Molecular

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

5

Sergio Aguilera

Reumatólogo

CLÍNICA INDISA

Santiago, Chile

1

Vinicius Ramos Henriques

Associate Professor

Advanced Center for Chronic Diseases - ACCDiS

Univesidad de Chile

Santiago, Chile

5

María Barrera

Profesor Asistente

Odontología

Universidad San Sebastián, Facultad de Odontología

Santiago, Chile

12

Sergio Gonzalez

Profesor titular

Patología General y Oral

Universidad Mayor

Santiago, Chile

10

Isabel Castro

Profesor Asistente

Tecnología Médica

Universidad de Chile

Santiago, Chile

1

DENISSE SEPULVEDA

Postdoc

Universidad Mayor de Chile

Santiago, Chile

5

Claudio Molina

Director Investigación

Investigación

Universidad San Sebastián

Santiago, Chile

1

Victor Aliaga

Postdoctorante

Universidad de O'Higgins

Santiago, Chile

2

Sebastián Indo

Assistant Professor

Department of Medical Technologist

Universidad de Chile

Santiago, Chile

16

PATRICIA CARVAJAL

Investigadora Postdoctoral

Tecnología Médica

Universidad de Chile

Santiago, Chile

2

Nicolas Albornoz

Investigador postdoctoral

Universidad San Sebastián

Puerto Monnt, Chile