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Isabel Verónica Castro Masso

Profesor Asistente

Universidad de Chile

Santiago, Chile

Glicobiología de las mucinas salivales y su alteración en pacientes con síndrome de Sjögren

Ciencias Biomédicas, UNIVERSIDAD DE CHILE. Chile, 2016
Tecnólogo Médico, UNIVERSIDAD DE CHILE. Chile, 2005
Ciencias Biológicas, UNIVERSIDAD DE CHILE. Chile, 2011

Profesor Asistente Full Time

UNIVERSIDAD DE CHILE

Medicina

Santiago, Chile

2012 - At present
Instructor Full Time

UNIVERSIDAD DE CHILE

Medicina

Santiago, Chile

2009 - 2011
Ayudante Full Time

UNIVERSIDAD DE CHILE

Medicina

Santiago, Chile

2006 - 2008

Profesor Asistente Full Time

Universidad de Chile

Santiago, Chile

2012 - At present


hsa-miR-424-5p and hsa-miR-513c-3p dysregulation mediated by IFN-y is associated with salivary gland dysfunction in Sjögren’s syndrome patients Carvajal, Patricia; Aguilera, Sergio; Jara, Daniela; Indo, Sebastián; Barrera, María José; González, Sergio; Molina, Claudio; Heathcote, Benjamín; Hermoso, Marcela; Castro, Isabel; González, María-Julieta Article WOS/ISI JOURNAL OF AUTOIMMUNITY (2023)
The integrated stress response is activated in the salivary glands of Sjogren's syndrome patients Carvajal, Patricia; Bahamondes, Veronica; Jara, Daniela; Castro, Isabel; Matus, Soledad; Aguilera, Sergio; Molina, Claudio; Gonzalez, Sergio; Hermoso, Marcela; Barrera, Maria-Jose; Gonzalez, Maria-Julieta Article ISI FRONTIERS IN MEDICINE (2023)
Identificación de macrófagos y virus Epstein-Barr en biopsias de pacientes con Síndrome de Sjögren. Gastón Negro; Isabel castro; Benjamín Martínez; Sergio Aguilera; Claudio Molina; Julieta González; Sergio González Article SCIELO International Journal of Interdisciplinary Dentistry (2022)
Small RNA Expression Profiling Reveals hsa-miR-181d-5p Downregulation Associated With TNF-a Overexpression in Sjögren’s Syndrome Patients. Castro, Isabel; Carvajal, Patricia; Jara, Daniela; Aguilera, Sergio; Heathcote, Benjamín; Barrera, María J.; Aliaga-Tobar, Víctor; Maracaja-Coutinho, Vinicius; Urzúa, Ulises; Quest, Andrew; González, Sergio; Molina, Claudio; Hermoso, Marcela; Gonzalez, MJ Article WOS SCOPUS FRONTIERS IN IMMUNOLOGY (2022)
Dysfunctional mitochondria as critical players in the inflammation of autoimmune diseases: Potential role in Sjögren's syndrome Barrera, María-José; Aguilera, Sergio; Castro, Isabel; Carvajal, Patricia; Jara, Daniela; Molina, Claudio; González, Sergio; González, María-Julieta Article WOS, SCOPUS AUTOIMMUNITY REVIEWS (2021)
Saliva sample for the massive screening of SARS-CoV-2 infection: a systematic review Canete, Martin Gonzalez; Valenzuela, Isidora Mujica; Garces, Patricia Carvajal; Masso, Isabel Castro; Gonzalez, Maria Julieta; Gonzalez, Sergio Article ISI Oral Surgery Oral Medicine Oral Pathology Oral Radiology (2021)
Tofacitinib counteracts IL-6 overexpression induced by deficient autophagy: implications in Sjögren's syndrome Barrera, María-José; Aguilera, Sergio; Castro, Isabel; Matus, Soledad; Carvajal, Patricia; Molina, Claudio; González, Sergio; Jara, Daniela; Hermoso, Marcela; González María-Julieta Article WOS, SCOPUS RHEUMATOLOGY (2021)
Type I Interferon Dependent hsa-miR-145-5p Downregulation Modulates MUC1 and TLR4 Overexpression in Salivary Glands From Sjögren's Syndrome Patients. Jara, Daniela; Carvajal, Patricia; Castro, Isabel; Barrera, María-José; Aguilera, Sergio; González, Sergio; Molina, Claudio; Hermoso, Marcela; González María-Julieta Article WOS, SCOPUS FRONTIERS IN IMMUNOLOGY (2021)
Aberrant MUC1 accumulation in salivary glands of Sjögren's syndrome patients is reversed by TUDCA in vitro. Castro I, Albornoz N, Aguilera S, Barrera MJ, González S, Núñez M, Carvajal P, Jara D, Lagos C, Molina C, Urzúa U, Hermoso MA, González MJ. Article ISI SCOPUS Rheumatology (Oxford, England) (2020)
Synaptotagmin-1 overexpression under inflammatory conditions affects secretion in salivary glands from Sjogren's syndrome patients Cortes, J; Hidalgo, J; Aguilera, S; Castro, I; Brito, M; Urra, H; Perez, P; Barrera, MJ; Carvajal, P; Urzua, U; Gonzalez, S; Molina, C; Bahamondes, V; Hermoso, M; Gonzalez, MJ Article ISI SCOPUS JOURNAL OF AUTOIMMUNITY (2019)
Association of high 5-hydroxymethylcytosine levels with Ten Eleven Translocation 2 overexpression and inflammation in Sjögren's syndrome patients Lagos, Carolina; Carvajal, Patricia; Castro, Isabel; Jara, Daniela; González, Sergio; Aguilera, Sergio; Barrera, María-José; Quest, Andrew F.G.; Bahamondes, Verónica; Molina, Claudio; Urzúa, Ulises; Hermoso, Marcela A.; Leyton, Cecilia; González, María-Julieta Article ISI SCOPUS Clinical Immunology (2018)
Endoplasmic reticulum stress in autoimmune diseases: Can altered protein quality control and/or unfolded protein response contribute to autoimmunity? A critical review on Sjogrens syndrome Barrera, Maria-Jose; Aguilera, Sergio; Castro, Isabel; Gonzalez, Sergio; Carvajal, Patricia; Molina, Claudio; Hermoso, Marcela A.; Gonzalez, Maria-Julieta Article ISI SCOPUS AUTOIMMUNITY REVIEWS (2018)
Impaired IRE1 alpha/XBP-1 pathway associated to DNA methylation might contribute to salivary gland dysfunction in Sjogrens syndrome patients Sepúlveda, Denisse; Barrera, María-José; Castro, Isabel; Aguilera, Sergio; Carvajal, Patricia; Lagos, Carolina; González, Sergio; Albornoz, Nicolás; Bahamondes, Verónica; Quest, Andrew F G; Urzúa, Ulises; Molina, Claudio; Leyton, Cecilia; Hermoso, Marcela A; González, María-Julieta Article ISI SCOPUS RHEUMATOLOGY (2018)
Pro-inflammatory cytokines enhance ERAD and ATF6 alpha pathway activity in salivary glands of Sjogren's syndrome patients Barrera, María-José; Aguilera, Sergio; Castro, Isabel; Cortés, Juan; Bahamondes, Verónica; Quest, Andrew F.G.; Molina, Claudio; González, Sergio; Hermoso, Marcela; Urzúa, Ulises; Leyton, Cecilia; González, María-Julieta Article ISI SCOPUS JOURNAL OF AUTOIMMUNITY (2016)
MUC1/SEC and MUC1/Y overexpression is associated with inflammation in Sjogren's syndrome Sung HH; Castro, I; Gonzalez S.; Aguilera, S; Smorodinsky NI; Quest, AFG; Bahamondes, V; Alliende C.; Cortes, J; Molina C.; Urzua, U; Barrera, MJ; Hermoso, M; Herrera L.; Leyton, C; Gonzalez, MJ Article ISI SCOPUS Oral Diseases (2015)
Salivary mucins induce a Toll-like receptor 4-mediated pro-inflammatory response in human submandibular salivary cells: are mucins involved in Sjogren's syndrome? Barrera, MJ; Aguilera, S; Veerman, E; Quest, AFG; Diaz-Jimenez, D; Urzua, U; Cortes, J; Gonzalez S.; Castro, I; Molina C.; Bahamondes, V; Leyton, C; Hermoso, MA; Gonzalez, MJ Article ISI SCOPUS Rheumatology (United Kingdom) (2015)


THREE DIMENSIONAL HSG CELLS CULTURE AS A MODEL TO STUDY THE EXOCITIC PROCESS IN SALIVARY GLANDS OF SJOGREN'S SYNDROME PATIENTS Cortes, J; Aguilera, S; Hidalgo J.; Bahamondes, V; Urra, H; Barrera, MJ; Castro, I; Molina C.; Gonzalez S.; Leyton, C; Gonzalez, MJ Abstract ISI ANNALS OF THE RHEUMATIC DISEASES (2014)
ARE SALIVARY MUCINS ABLE TO TRIGGER A PROINFLAMMATORY RESPONSE? Barrera, MJ; Aguilera, S; Hermoso, M; Langjahr P.; Cortes, J; Castro, I; Molina C.; Gonzalez S.; Alliende C.; Bahamondes, V; Sepulveda D.; Leyton, C; Gonzalez, MJ Abstract ISI ANNALS OF THE RHEUMATIC DISEASES (2013)


Arquitectura y remodelamiento de la matriz extracelular en glándulas salivales en el síndrome de Sjögren Claudio Molina; Sergio González; Isabel Castro; María-José Barrera; Sergio Aguilera ; María-Julieta González; Anaya, J.M.; Sarmiento-Monroy, J.C.; García-Carrasco, M. BookSection (2017)
Mucins in Salivary Gland Development, Regeneration, and Disease Castro, Isabel; Barrera, María-José; González, Sergio; Aguilera, Sergio; Urzúa, Ulises; Cortés, Juan; González, María- Julieta; Seunghee Cha, DDS, PhD BookSection (2017)


Pro-inflammatory cytokines induce a Golgi stress condition in salivary glands from Sjögren’s syndrome patients and H2S diminishes such stress condition Castro Masso, Isabel; Aguilera, Sergio; González, Sergio; Molina, Claudio; González, María-Julieta Proyecto (2023)
Cellular stress induced by inflammation alters miRNAs metabolism in salivary glands of Sjögren’s syndrome patients González, María-Julieta; Castro, Isabel; Aguilera, Sergio; Molina, Claudio; González, Sergio; Barrera, María José Proyecto (2021)
ASSESSING THE ROLE OF GOLGINS IN THE LOCALIZATION OF GOLGI ENZYMES AND O-GLYCOSYLATION OF SALIVARY MUCINS Castro Masso, Isabel Proyecto (2017)
Cytokines induce alterations in stress response pathways of the endoplasmic reticulum in salivary glands of Sjogrens syndrome patients: can these be modulated by epigenetic mechanisms? Maria Julieta González Burgos Proyecto (2016)


Oral dryness in Sjogren's syndrome patients. Not just a question of water Castro, I; Sepulveda D.; Cortes, J; Quest, AFG; Barrera, MJ; Bahamondes, V; Aguilera, S; Urzua, U; Alliende C.; Molina C.; Gonzalez S.; Hermoso, MA; Leyton, C; Gonzalez, MJ Review ISI SCOPUS Autoimmunity Reviews (2013)
Sjogren's syndrome and the epithelial target: A comprehensive review Barrera, MJ; Bahamondes, V; Sepulveda D.; Quest, AFG; Castro, I; Cortes, J; Aguilera, S; Urzua, U; Molina C.; Perez, P.; Ewert, P; Alliende C.; Hermoso, MA; Gonzalez S.; Leyton, C; Gonzalez, MJ Review ISI SCOPUS Journal of Autoimmunity (2013)

26

Isabel Castro

Profesor Asistente

Tecnología Médica

Universidad de Chile

Santiago, Chile

12

Maria González

Academico

FACULTAD DE MEDICINA - UNIVERSIDAD DE CHILE

Santiago, Chile

10

Claudio Molina

Director Investigación

Investigación

Universidad San Sebastián

Santiago, Chile

10

Marcela Hermoso

Full Professor

School of Medicine

UNIVERSIDAD DE CHILE

Santiago, Chile

9

Sergio Gonzalez

Profesor titular

Patología General y Oral

Universidad Mayor

Santiago, Chile

8

Sergio Aguilera

Reumatólogo

CLÍNICA INDISA

Santiago, Chile

7

PATRICIA CARVAJAL

5

María Barrera

Profesor Asistente

Odontología

Universidad San Sebastián, Facultad de Odontología

Santiago, Chile

4

ULISES URZUA

Assistant Professor

ICBM

UNIVERSIDAD DE CHILE

Santiago, Chile

2

Andrew Quest

Full Professor

Biologia Celular y Molecular

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

2

Nicolas Albornoz

Investigador postdoctoral

Universidad San Sebastián

Puerto Monnt, Chile

2

DENISSE SEPULVEDA

Postdoc

Universidad Mayor de Chile

Santiago, Chile

1

David Diaz

Asistente de Investigación

Instituto de Ciencias Biomédicas, Facultad de Medicina

Universidad de Chile

Santiago, Chile

1

Hery Urra

Staff scientist

INSTITUTO DE NEUROCIENCIA BIOMEDICA (BNI)

Santiago, Chile