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SATHISH MANDA

Profesor (adjunto)

Universidad Católica del Maule

Talca, Chile

Participo principalmente en programas de investigación multidisciplinarios, que incluyen Química Orgánica / Medicinal, desarrollo de nuevas metodologías y síntesis asimétrica para la construcción de moléculas bioactivas y nuevas entidades químicas.

Doctorado en Química, UNIVERSITY OF OSMANIA. India, 2018
Magister en Ciencias mención Química, KAKATIYA UNIVERSITY. Chile, 2006
Bachillerato en Ciencias mención Química, KAKATIYA UNIVERSITY. Chile, 2004
Diplomado de Educación Basado en Competencias 2020, UNIVERSIDAD DE TALCA. Chile, 2020
DIPLOMADO EN DOCENCIA UNIVERSITARIA PARA EL APRENDIZAJE PROFUNDO Y LA INNOVACIÓN EDUCATIVA, Universidad Catolica del Maule. Chile, 2025

Responsible Researcher for Fondecyt project (11200555) Other

UNIVERSIDAD DE TALCA

Talca, Chile

2021 - 2021
Conferenciante Full Time

UNIVERSIDAD DE TALCA

Talca, Chile

2018 - 2020
Profesor (adjunto) Full Time

UNIVERSIDAD CATOLICA DEL MAULE

Talca, Chile

2021 - At present

Associate Scientist Full Time

Laxai Life Sciences

Hyderabad, India

2018 - 2018
Research Scientist Full Time

VIDGAS SCIENCE AND TECHNOLOGIES PVT. LTD.

Hyderabad, India

2017 - 2018
Research Associate Full Time

GVK Biosciences

Hyderabad, India

2010 - 2012
Research Chemist Full Time

TCG Lifescience

Pune, India

2008 - 2010

UGC-Junior Research Fellow

INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY

India, 2012

I have participated in “University Grant Commission (UGC)” a Nationwide competition in India for the PhD Scholarship and qualified “JUNIOR RESEARCH FELLOWSHIP” with rank of 82/748.
UGC-Senior Research Fellow

INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY

Chile, 2014

I was promoted from UGC-Junior Research Fellow to UGC-Senior Research Fellow in 2014 to 2017.


Fabrication of porous nano silica materials by template-assisted strategy for controlled drug delivery studies Chirra, Suman; Gujjula, Sripal Reddy; Manda, Sathish; Goskula, Srinath; Narayanan, Venkatathri Article ISI JOURNAL OF POROUS MATERIALS (2025)
Reclassification of <i>Salinisphaera halophila</i> Zhang et al. 2012 as a Later Heterotypic Synonym of <i>Salinisphaera orenii</i> Park et al. 2012 Quadri, Syed Raziuddin; Sathish, Manda; Quach, Ngoc Tung; Li, Wen-Jun; Rao, Manik Prabhu Narsing Article ISI CURRENT MICROBIOLOGY (2025)
Genomic characterization of Puccinia triticina using molecular marker technology Usman, M.; Habib, M.; Sathish, M.; Iqbal, S.; Altaf, J.; Ahmad, Z.; ur Rehman, A.; Khan, A. I.; Maqbool, R.; Hussain, S.; et al. Article ISI Brazilian Journal of Biology (2024)
Microwave-Assisted One-Pot Synthesis of Tetrahydro-β-Carbolines by Fe(II)-Catalyst: Utilizing Methanol as Methylene Synthon Khan, Mursalim A.; Reddyrajula, Rajkumar; Sakla, Akash P.; Sathish, Manda; Shankaraiah, Nagula Article ISI ASIAN JOURNAL OF ORGANIC CHEMISTRY (2024)
Pd-Co bimetallic nanoparticles modified α-FeOOH nanorod for the catalytic reduction of organic pollutants Manikandan, Velu; Packiaraj, S.; de Leon, J. Noe Diaz; Song, Kwang Soup Article ISI JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING (2024)
Pd-Monothiosquaramides: Efficient Catalysts for the Enantioselective Imine Reduction of Dihydro-β-Carbolines Reis, Francisco A. A.; Sathish, Manda; Villasenor, Jorge; Nachtigall, Fabiane M.; Santos, Leonardo S. Article ISI ASIAN JOURNAL OF ORGANIC CHEMISTRY (2024)
Plant Nitrogen Metabolism: Balancing Resilience to Nutritional Stress and Abiotic Challenges Farhan, Muhammad; Sathish, Manda; Kiran, Rafia; Mushtaq, Aroosa; Baazeem, Alaa; Hasnain, Ammarah; Hakim, Fahad; Naqvi, Syed Atif Hasan; Mubeen, Mustansar; Iftikhar, Yasir; et al. Article ISI PHYTON-INTERNATIONAL JOURNAL OF EXPERIMENTAL BOTANY (2024)
Regiospecific Synthesis of Thioether-Linked 3-Hydroxy Oxindoles From Spiroepoxy Oxindoles and Their Cytotoxicity Evaluation Kabra, Pratik; Sakla, Akash P.; Kumar, Manisurya; Sathish, Manda; Dandekar, Manoj P.; Shankaraiah, Nagula Article ISI CHEMISTRYSELECT (2024)
Sparkling jewels of innovation: Revolutionizing environmental solutions with spinel-infused advanced nanomaterials, unveiling today's insights, and illuminating tomorrow's frontiers Soni, Ritika; Thakur, Ankush; Ghotekar, Suresh; Lokhande, P. E.; Aepuru, Radhamanohar; Sathish, Manda; Kumar, Deepak; Mubarak, Nabisab Mujawar Article ISI JOURNAL OF ALLOYS AND COMPOUNDS (2024)
A Short Review on Conducting Polymer Nanocomposites Jadoun, Sapana; Chauhan, Narendra Pal Singh; Chinnam, Sampath; Aepuru, Radhamanohar; Sathish, Manda; Chundawat, Narendra Singh; Rahdar, Abbas Article SCOPUS (2023)
Design, synthesis and in vitro cytotoxic evaluation of 8-carboline tethered quinoline-4-carboxamide conjugates as DNA-interactive Topo II inhibitors Devi, Priyanka; Chemitikanti, Sowjanya; Swamy, Chintha Venkata Dinesh; Phanindranath, Regur; Shankaraiah, Nagula Article ISI SCOPUS JOURNAL OF MOLECULAR STRUCTURE (2023)
Sustainable photocatalytic C-H annulation of heteroarenes with sulfoxonium ylides: synthesis and photophysical properties of fused imidazo[1,2-<i>a</i>]pyridine-based molecules Dannarm, Srinivas Reddy; Dastari, Sowmya; Sonti, Rajesh; Shankaraiah, Nagula Article ISI ORGANIC CHEMISTRY FRONTIERS (2023)
Trimethylsilyl azide-promoted acid-amine coupling: A facile one-pot route to amides from carboxylic acids and amines Shankaraiah, Nagula Article ISI SCOPUS ARKIVOC (2023)
Visible-light-mediated photocatalytic sequential <i>N</i>-arylation: an eco-friendly synthetic route to unsymmetrical diarylamines and the imatinib drug Reddy, Dannarm Srinivas; Shankaraiah, Nagula Article ISI SCOPUS ORGANIC CHEMISTRY FRONTIERS (2023)
Brown Seaweed-Derived Alginic Acid: An Efficient and Reusable Catalyst for Pictet-Spengler Reaction to Access Tetrahydro-β-Carboline and Tetrahydroisoquinoline Frameworks Soni, Jay Prakash; Sathish, Manda; Nachtigall, Fabiane M.; Santos, Leonardo S.; Shankaraiah, Nagula Article ISI ASIAN JOURNAL OF ORGANIC CHEMISTRY (2022)
Catalyst-Free Site-Selective Diverse Functionalization of Inherent C-H Bonds in 1-Aryl-β-carbolines, Norharmane and Harmine Soni, Jay Prakash; Kumawat, Akshay; Yadav, Sachin; Jadhav, Nayan Arvind; Shankaraiah, Nagula Article ISI SCOPUS CHEMISTRYSELECT (2022)
Enantioselective Imine Reduction of Dihydro-beta-carbolines by Fe- Thiosquaramide Catalyst Nachtigall, Fabiane M. Article ISI SCOPUS ORGANIC LETTERS (2022)
Enantioselective Imine Reduction of Dihydro-β-carbolines by Fe- Thiosquaramide Catalyst Sathish, Manda; Nachtigall, Fabiane M.; Santos, Leonardo S. Article ISI ORGANIC LETTERS (2022)
Green Chemistry Based Synthesis of Zinc Oxide Nanoparticles Using Plant Derivatives of <i>Calotropis gigantea</i> (Giant Milkweed) and Its Biological Applications against Various Bacterial and Fungal Pathogens Farooq, Ammara; Khan, Umair A.; Ali, Haider; Sathish, Manda; Naqvi, Syed Atif Hasan; Iqbal, Shehzad; Mubeen, Iqra; Amir, Muhammad Bilal; Mosa, Walid F. A.; Baazeem, Alaa; et al. Article ISI MICROORGANISMS (2022)
Green Chemistry Based Synthesis of Zinc Oxide Nanoparticles Using Plant Derivatives of Calotropis gigantea (Giant Milkweed) and Its Biological Applications against Various Bacterial and Fungal Pathogens Farooq, Ammara; Khan, Umair A.; Ali, Haider; Amir, Muhammad Bilal; Mosa, Walid F.A.; Baazeem, Alaa; Moustafa, Mahmoud; Alrumman, Sulaiman; Shati, Ali; Negm, Sally Article ISI SCOPUS Microorganisms (2022)
Rh(III)-catalysed site-selective alkylation of beta-carbolines/isoquinolines and tandem C-H/C-N functionalization to construct indolizine-indole frameworks John, Stephy Elza; Galla, Mary Sravani; Shankaraiah, Nagula Article ISI SCOPUS Molecular Catalysis (2022)
Rh(III)-catalysed site-selective alkylation of β-carbolines/isoquinolines and tandem C-H/C-N functionalization to construct indolizine-indole frameworks Bora, Darshana; John, Stephy Elza; Galla, Mary Sravani; Sathish, Manda; Shankaraiah, Nagula Article ISI MOLECULAR CATALYSIS (2022)
Role of Promising Secondary Metabolites to Confer Resistance Against Environmental Stresses in Crop Plants: Current Scenario and Future Perspectives Mubeen, Bismillah; Hasnain, Ammarah; Adrees, Muhammad; Mahmoud, Eman A.; Alaklabi, Abdullah; Din, Ghulam Muhae Ud Article ISI SCOPUS FRONTIERS IN PLANT SCIENCE (2022)
Synthesis, characterization, photocatalytic effect of CuS-ZnO nanocomposite on photodegradation of Congo red and phenol pollutant Mir, Tahir ul Gani; Amin, Owais Article ISI SCOPUS INORGANIC CHEMISTRY COMMUNICATIONS (2022)
Taxonomy, distribution, epidemiology, disease cycle and management of brown rot disease of peach<i> (Monilinia</i> spp.) Iqbal, Shehzad; Abbas, Aqleem; Mubeen, Iqra; Razaq, Zarafshan; Syed, Sartaj-Alam; Naqvi, Syed Atif Hasan Article ISI SCOPUS Notulae Botanicae Horti Agrobotanici Cluj-Napoca (2022)
Zn alleviated salt toxicity in<i> Solanum</i><i> lycopersicum</i> L. seedlings by reducing Na<SUP>+</SUP> transfer, improving gas exchange, defense system and Zn contents Ahmad, Ijaz; Ahmad, Salman; Okla, Mohammad K.; Al-Amri, Saud S.; Alaraidh, Ibrahim A. Article ISI SCOPUS PLANT PHYSIOLOGY AND BIOCHEMISTRY (2022)
Design, Synthesis and Biological Evaluation of Hybrid C3-Quinazolinone linked ?-carboline Conjugates as DNA Intercalative Topoisomerase I Inhibitors Yellaiah, Tangella; Manda, Sathish; Kadagathur Manasa; Nagesh Narayana; Nagendra Babu Bathini Article JSM Clinical Pharmaceutics (2021)
TCCA-mediated oxidative rearrangement of tetrahydro-β-carbolines: facile access to spirooxindoles and the total synthesis of (±)-coerulescine and (±)-horsfiline Sakla, Akash P.; Nachtigall, Fabiane M.; Shankaraiah, Nagula Article ISI SCOPUS RSC ADVANCES (2021)
Bifunctional thiosquaramide catalyzed asymmetric reduction of dihydro-β-carbolines and enantioselective synthesis of (-)-coerulescine and (-)-horsfiline by oxidative rearrangement Nachtigall, Fabiane M. Article ISI SCOPUS RSC ADVANCES (2020)
Synthesis and in vitro cytotoxicity evaluation of beta-carboline-combretastatin carboxamides as apoptosis inducing agents: DNA intercalation and topoisomerase-II inhibition Reddy, T. Srinivasa; Bhargava, Suresh K.; Shankaraiah, Nagula; Nagesh Narayana; Kamal, Ahmed Article ISI BIOORGANIC & MEDICINAL CHEMISTRY (2019)
Synthesis of Combretastatin-A4 Carboxamidest that Mimic Sulfonyl Piperazines by a Molecular Hybridization Approach: in vitro Cytotoxicity Evaluation and Inhibition of Tubulin Polymerization Jadala, Chetna; Sathish, Manda; Anchi, Pratibha; Lakshmi, Uppu Jaya; Reddy, Velma Ganga; Shankaraiah, Nagula; Godugu, Chandraiah; Kamal, Ahmed Article ISI CHEMMEDCHEM (2019)
Synthesis of DNA interactive C3-trans-cinnamide linked beta-carboline conjugates as potential cytotoxic and DNA topoisomerase I inhibitors Dushantrao, Sabanis Chetan; Nekkanti, Shalini; Thatikonda, Soujanya; Tangella, Yellaiah; Srinivas, Gunda; Cherukommu, Shirisha; Krishna, Namballa Hari; Shankaraiah, Nagula; Kamal, Ahmed Article ISI BIOORGANIC & MEDICINAL CHEMISTRY (2018)
Synthesis of podophyllotoxin linked beta-carboline congeners as potential anticancer agents and DNA topoisomerase II inhibitors Kavitha, Botla; Nayak, V. Lakshma; Ajitha, Ayyappan; Alarifi, Abdullah; Shankaraiah, Nagula; Kamal, Ahmed Article ISI EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2018)
An efficient one-pot approach for the regio- and diastereoselective synthesis of trans-dihydrofuran derivatives: cytotoxicity and DNA-binding studies Nayak, V. Laxma; Sridhar, B.; Kamal, Ahmed Article ISI ORGANIC & BIOMOLECULAR CHEMISTRY (2017)
Diphenylphosphoryl Azide (DPPA)-Mediated One-Pot Synthesis of Oxazolo[4,5-c][1,8]naphthyridin-4(5 H)-ones, Oxazolo[4,5-c]quinoline-4(5 H)-ones, and Tosyloxazol-5-yl Pyridines Manasa, Kesari Lakshmi; Kamal, Ahmed Article ISI ASIAN JOURNAL OF ORGANIC CHEMISTRY (2017)
Phenacyl azides as efficient intermediates: one-pot synthesis of pyrrolidines and imidazoles Reddy, Chada Narsimha; Adhikary, Susanta; Nanubolu, Jagadeesh Babu; Maurya, Ram Awatar; Kamal, Ahmed Article ISI ORGANIC & BIOMOLECULAR CHEMISTRY (2017)
Design and synthesis of C3-tethered 1,2,3-triazolo-beta- carboline derivatives: Anticancer activity, DNA-binding ability, viscosity and molecular modeling studies Shankaraiah, Nagula; Senwar, Kishna Ram; Shrivastava, Shweta; Naidu, V. G. M.; Kamal, Ahmed Article ISI BIOORGANIC CHEMISTRY (2016)
Iron-Mediated One-Pot Synthesis of 3,5-Diarylpyridines from beta-Nitrostyrenes Chetna, Jadala; Shankaraiah, Nagula; Kamal, Ahmed Article ISI JOURNAL OF ORGANIC CHEMISTRY (2016)
Phenyliodonium Diacetate Mediated One-Pot Synthesis of Benzimidazoles and Quinazolinones from Benzylamines Kamal, Ahmed Article ISI CHEMISTRYSELECT (2016)
Silver catalyzed domino aza-annulation/Diels-Alder cyclization of 2-ene-yne anilines: a facile one-pot access to carbazole, dihydrocarbazole and tetrahydrocarbazole frameworks Saraswati, A. Prasanth; Shankaraiah, Nagula; Kamal, Ahmed Article ISI CHEMICAL COMMUNICATIONS (2016)
A one-pot 'click' reaction from spiro-epoxides catalyzed by Cu(I)-pyrrolidinyl-oxazole-carboxamide Kamal, Ahmed; Shankaraiah, Nagula Article ISI NEW JOURNAL OF CHEMISTRY (2015)
An efficient one-pot decarboxylative aromatization of tetrahydro-beta-carbolines by using N-chlorosuccinimide: total synthesis of norharmane, harmane and eudistomins Kamal, Ahmed; Prasanthi, A. V. G.; Srinivasulu, Vunnam; Shankaraiah, Nagula Article ISI RSC ADVANCES (2015)
Design and synthesis of dithiocarbamate linked beta-carboline derivatives: DNA topoisomerase II inhibition with DNA binding and apoptosis inducing ability Kamal, Ahmed; Srinivasulu, Vunnam; Thummuri, Dinesh; Bagul, Chandrakant; Shankaraiah, Nagula Article ISI BIOORGANIC & MEDICINAL CHEMISTRY (2015)
Dithiocarbamate/piperazine bridged pyrrolobenzodiazepines as DNA-minor groove binders: Synthesis, DNA-binding affinity and cytotoxic activity Kamal, Ahmed; Sreekanth, Kokkonda; Shankaraiah, Nagula; Srinivasulu, Vunnam Article ISI BIOORGANIC CHEMISTRY (2015)
DNA-binding affinity and anticancer activity of beta-carboline-chalcone conjugates as potential DNA intercalators: Molecular modelling and synthesis Shankaraiah, Nagula; Siraj, K. P.; Srinivasulu, Vunnam; Vishnuvardhan, M. V. P. S.; Ramakrishna, Sistla; Kamal, Ahmed Article ISI BIOORGANIC CHEMISTRY (2015)
PhI(OAc)(2)-mediated one-pot oxidative decarboxylation and aromatization of tetrahydro-beta-carbolines: synthesis of norharmane, harmane, eudistomin U and eudistomin I Kamal, Ahmed; Srinivasulu, Vunnam Article ISI ORGANIC & BIOMOLECULAR CHEMISTRY (2015)
Synthesis and biological evaluation of benzimidazole-oxindole conjugates as microtubule-targeting agents Kamal, Ahmed; Nagaseshadri, B.; Srinivasulu, Vunnam; Kapure, Jeevak Sopanrao; Reddy, C. Suresh Article ISI BIOORGANIC CHEMISTRY (2015)
Asymmetric Michael addition of ketones to nitroolefins: pyrrolidinyl-oxazole-carboxamides as new efficient organocatalysts Kamal, Ahmed; Srinivasulu, Vunnam; Shekar, Kunta Chandra; Shankaraiah, Nagula Article ISI ORGANIC & BIOMOLECULAR CHEMISTRY (2014)
Design and Synthesis of C3-Pyrazole/Chalcone-Linked Beta-Carboline Hybrids: Antitopoisomerase I, DNA-Interactive, and Apoptosis-Inducing Anticancer Agents Kamal, Ahmed; Srinivasulu, Vunnam; Shankaraiah, Nagula; Reddy, N. V. Subba; Rangaraj, Nandini Article ISI CHEMMEDCHEM (2014)
Palladium-Catalyzed Aryl C-H Activation and Tandem ortho- Hydroxylation/Alkoxylation of 2-Aryl Benzimidazoles: Cytotoxicity and DNA-Binding Studies Kamal, Ahmed; Srinivasulu, Vunnam; Rao, M. P. Narasimha; Shankaraiah, Nagula Article ISI ASIAN JOURNAL OF ORGANIC CHEMISTRY (2014)
AlCl3-NaI assisted cleavage of polymer-bound esters with concomitant amine coupling and azido-reductive cyclization: synthesis of pyrrolobenzodiazepine derivatives Kamal, Ahmed; Prabhakar, S.; Shankaraiah, Nagula; Markandeya, Nagula; Reddy, P. Venkat; Sriniyasulu, Vunnam Article ISI TETRAHEDRON LETTERS (2013)


Future of Drug Discovery Kamal, Ahmed; Nagula, Shankaraiah BookReview Drug Resistance in Bacteria, Fungi, Malaria, and Cancer (2017)


TCICA mediated synthesis of Spirooxindole by Oxidative Rearrangement of Tetrahydro-β-carbolines: Total synthesis of Coerulescine, Elacomine and Horsfiline ConferencePoster (2020)


N-((1-phenyl-9H-pyrido[3,4-b]indol-3-yl)methyl)cinnamamides as potential anticancer agents and preparation thereof Kamal, Ahmed; Manda, Sathish; Narayana, Nagesh; Nagula, Shankaraiah; Dushantrao, Sabanis C.; Namballa, Hari K. Patent (2019)
N-((1-phenyl-9h-pyrido[3,4-b]indol-3-yl)methyl)cinnamamides as anticancer agents and preparation thereof Kamal, Ahmed; Nagula, Shankaraiah Patent (2017)


Development of New Thiosquaramides and Thiodeltamides Organocatalysts for the Asymmetric Synthesis of Bioactive Compounds Proyecto (0)


Advancements in Carbon Dot Production and Characterization for Food Packaging: A Comprehensive Review Priya, Sathiya; Henry, J.; Aepuru, Radhamanohar; Arivizhivendhan, K. V.; Sathish, Manda Review ISI BRAZILIAN JOURNAL OF PHYSICS (2024)
Recent advancements in sustainable synthesis of zinc oxide nanoparticles using various plant extracts for environmental remediation Review ISI ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH (2024)