Bioengineering and biotechnology, biopharmaceutical production (vaccines, monoclonal antibodies and antibiotics), optimization of cell lines, media and production processes, metabolic engineering, fermentation, systems biology, omics

DIRECTED THESES
PhD:
Nicolas E Zaragoza. (2020). Thesis: “Characterising quorum sensing regulation in Clostridium tetani E88 fermentation”. The University of Queensland. Australia. Co-supervisor.
Undergraduate:
B. Eng (Hons.) Nicholas Cowie. (2017). Thesis: “Increasing TeNT Production in C. tetani Using Machine Learning”. The University of Queensland. Australia. Co-supervisor.

LAB FORMATION
Kanupriya Tiwari, Aude Durand, Nicolás Zaraoza, Nicholas Cowie, Craig Barry and Rosemary Gillane.

CONFERENCE PRESENTATIONS & POSTERS
1. C.A. Orellana, N. Zaragoza, C. Licona-Cassani, G. Moonen, G. Moutafis, J. Power, L.K. Nielsen, E. Marcellin. Improving tetanus toxoid vaccine production. BLiSS. Brisbane, Australia. 24 November 2017. Poster.
2. C.A. Orellana, N. Zaragoza, C. Licona-Cassani, G. Moonen, G. Moutafis, J. Power, L.K. Nielsen, E. Marcellin. Improving tetanus toxoid vaccine production. International Conference in BioNano Innovation. Brisbane, Australia. 24-27 September 2017. Poster.
3. C.A. Orellana, E. Marcellin., T. Munro, P.P. Gray, L.K. Nielsen. Multi-omics approach for comparative studies of monoclonal antibody producing CHO cells. 24th European Society for Animal Cell Technology (ESACT) meeting. Barcelona, Spain. 31 May – 3 June, 2015. Oral presentation.
4. C.A. Orellana, T. Munro, P.P Gray, E. Marcellin, L.K. Nielsen. A systems biology approach to improve host cells for biopharmaceutical production. 3rd International NanoBio Conference. Brisbane, Australia. 7-10 July, 2014. Oral presentation.
5. C.A. Orellana, T. Munro, P.P Gray, E. Marcellin, L.K. Nielsen. A systems biology approach to improve host cells for biopharmaceutical production. Cell Culture Engineering XIV. Quebec City, Canada. 4-9 May, 2014. Poster and oral presentation in workshop “Applications of –omics technology”.
6. C.A. Orellana, P.P. Gray, L.K. Nielsen, T. Munro. A systems biology approach to improve host cells for biopharmaceutical production. The Bioprocessing Network 2013 Conference. Gold Coast, Australia. 22-24 October, 2013. Oral presentation.
7. C.A. Orellana, M. Song, P.P. Gray, L.K. Nielsen, T. Munro. Improving host cells for biopharmaceutical production. 1st International Conference on BioNano Innovation. Brisbane, Australia. 19-20 July, 2012. Poster.
8. J. Asenjo, C.A. Orellana, B. Andrews. Mathematical modeling of a protein mixture in chromatography applied to high protein concentrations and optimal selection of operating conditions. 15th International Conference on Biopartitioning and Purification. Uxbridge, UK. 14-19 June, 2009. Oral presentation by J. Asenjo.
9. J. Asenjo, C.A. Orellana, B. Andrews. Mathematical modeling of a protein mixture in chromatography applied to high protein concentrations and optimal selection of operating conditions. 6th HIC/RPC Bioseparation Conference: Advancements, Applications and Theory in Downstream Processing. Napa, CA. 15-19 Mach, 2009. Oral presentation by J. Asenjo.

CONFERENCE ORGANIZATION
1st Meeting of Chilean Scientists in Brisbane, 31 July 2015 at the Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, Brisbane, Australia.
The aim was to strengthen ties between the Chilean and Australian scientific communities. The invitation was open to all Chilean researchers residing in Australia as well as important Australian and Chilean researchers from a broad scientific background, especially those from Biological Sciences, Veterinary Sciences, Medical Sciences, Chemistry, Biotechnology and Engineering.