Eduardo Nicolas Fuentes Jofre

Founder and CEO


santiago, Chile

Líneas de Investigación

Past: Molecular Endocrinology and Physiology Present: Academic Writing and Editing, Artificial Intelligence, Natural Language Processing, Machine Learning


  •  Biotechnology, Universidad Andres bello. Chile, 2012
  •  Marine Biology, Universidad Andres bello. Chile, 2007
  •  Marine Biology, Universidad Andres Bello. Chile, 2007
  •  Marine Sciences , Universidad Andres Bello. Chile, 2005

Experiencia Académica

  •   University-level Lecturer, Coordinator, and Laboratory and Seminar Teaching Assistant. Part Time

    Universidad Andres Bello


    2006 - 2015

Experiencia Profesional

  •   Founder and CEO Full Time


    santiago, Chile

    2015 - A la fecha

  •   Post-Doctoral Research Fellow Full Time

    University of St. Andrews and Aberdeen

    Reino Unido

    2014 - A la fecha

  •   Post-Doctoral Research Fellow Full Time



    2013 - 2014

Formación de Capital Humano

Director and tutor of 2 Master’s thesis in Biotechnology (~2 years in duration)

10 years of experience as a University-level Lecturer, Coordinator, and Laboratory and Seminar Teaching Assistant. During these 10 years I have taught 6 different courses equivalent to ~69 hours of lectures; ~512 hours of laboratory teaching; ~256 hours of seminars.

Supervision of 3 PhD (~6 months) and 3 undergraduate research unit (~6 months in duration)

As entrepreneur with my enterprise (BioPub) I have trained over 500 scientists in scientific writing from undergraduate students to full Professors from national (UCHILE, PUC, UACH; UDEC; UNAB) and international (UTEXAS) universities

Difusión y Transferencia

Currently working on a new intelligent (artificial intelligence) computational multi-linguistic level model (morph-syntax, semantic, and coherence-cohesion) for automatic assessment (machine learning), editing, and feedback specialized for scientific documents. This will be translated in time reduction, and higher quality and reproducible for writing and editing scientific documents. Therefore, always is obtained a well written document that communicates effectively discoveries to other scientist and society. Besides the aforementioned social impact that this technology can have in the world, in economic terms the aim is to massively sell this software worldwide.

Premios y Distinciones

  •   Post-Doctoral Research Fellowship

    University of Saint Andrews

    Reino Unido, 2014

    Academic Excellence

  •   Post-Doctoral Research Fellowship


    Chile, 2013

    Reason: Academic Excellence.

  •   Trainee Award 7th International Symposium on Fish Endocrinology

    International Society of Fish Endocrinology

    Argentina, 2012

    Reason: Academic Excellence.

  •   PhD Research Fellowship (Becas Chile)


    Chile, 2009

    Reason: Academic Excellence.

  •   Scientific congress award

    International Society of Fish Biology

    Estados Unidos, 2010

    Best poster presentation,

  •   PhD scholarship


    Chile, 2008

    Reason: Academic Excellence.

  •   Best student of the class


    Chile, 2007

    Best student of the class, Master’s in Marine Biology, Marine Biologist, and Bachelor’s in Marine Sciences.

  •   Andres Bello University Scholarship.


    Chile, 2004

    Reason: Academic excellence.


Article (20)

Divergent regulation of insulin-like growth factor binding protein genes in cultured Atlantic salmon myotubes under different models of catabolism and anabolism
The TORC1/P70S6K and TORC1/4EBP1 signaling pathways have a stronger contribution on skeletal muscle growth than MAPK/ERK in an early vertebrate: Differential involvement of the IGF system and atrogenes
Sequencing and de novo assembly of the red cusk-eel (Genypterus chilensis) transcriptome
Skeletal muscle plasticity induced by seasonal acclimatization involves IGF1 signaling: Implications in ribosomal biogenesis and protein synthesis
The vertebrate muscle-specific RING finger protein family includes MuRF4–A novel, conserved E3-ubiquitin ligase
IGF‐1 Induces IP3‐dependent Calcium Signal Involved in the Regulation of Myostatin Gene Expression Mediated by NFAT During Myoblast Differentiation
Isolation and selection of suitable reference genes for real-time PCR analyses in the skeletal muscle of the fine flounder in response to nutritional status: assessment and normalization of gene expression of growth-related genes
Nutritional status modulates plasma leptin, AMPK and TOR activation, and mitochondrial biogenesis: implications for cell metabolism and growth in skeletal muscle of the fine flounder
Regulation of skeletal muscle growth in fish by the growth hormone–insulin-like growth factor system
The cAMP response element binding protein (CREB) is activated by insulin-like growth factor-1 (IGF-1) and regulates myostatin gene expression in skeletal myoblast
Transient inactivation of myostatin induces muscle hypertrophy and overcompensatory growth in zebrafish via inactivation of the SMAD signaling pathway
Catabolic Signaling Pathways, Atrogenes, and Ubiquitinated Proteins Are Regulated by the Nutritional Status in the Muscle of the Fine Flounder
Dynamic transcriptional regulation of autocrine/paracrine igfbp1, 2, 3, 4, 5, and 6 in the skeletal muscle of the fine flounder during different nutritional statuses
Inherent Growth Hormone Resistance in the Skeletal Muscle of the Fine Flounder Is Modulated by Nutritional Status and Is Characterized by High Contents of Truncated GHR, Impairment in the JAK2/STAT5 Signaling Pathway, and Low IGF-I Expression
Plasma leptin and growth hormone levels in the fine flounder (Paralichthys adspersus) increase gradually during fasting and decline rapidly after refeeding
IGF-I/PI3K/Akt and IGF-I/MAPK/ERK pathways in vivo in skeletal muscle are regulated by nutrition and contribute to somatic growth in the fine flounder
Molecular cloning of IGF-1 and IGF-1 receptor and their expression pattern in the Chilean flounder (Paralichthys adspersus)
Dynamic expression pattern of the growth hormone receptor during early development of the Chilean flounder
Temporal and spatial expression pattern of the myostatin gene during larval and juvenile stages of the Chilean flounder (Paralichthys adspersus)
Skeletal muscle plasticity induced by seasonal acclimatization in carp involves differential expression of rRNA and molecules that epigenetically regulate its synthesis
Eduardo Fuentes

Founder and CEO


santiago, Chile

Juan Valdés

Head lab

Ciencias Biologicas


Santiago, Chile

Alfredo Molina



Marco Alvarez

Full Professor

Department of Biological Science

Universidad Andres Bello

Viña del Mar, Chile


Medical Education and Clinical Simulation Director

Academic Vice Rectory


Santiago, Chile

Pamela Ruiz


Centro de Biotecnología

Universidad de Concepción

Concepción, Chile