Man

Alfredo Ivan Molina Sirguiado

UNIVERSIDAD ANDRES BELLO

SANTIAGO, Chile

Líneas de Investigación


Fisiologa Celular; Biología Celular y Molecular; Biología Molecular; Fisiología molecular de peces; Biotecnologia; Endocrinologia; Fisiología del Crecimiento Musculo Esqueletico; Peces y acuicultura; Gene expression during carp acclimatization; Functional Proteomics of Cyprinus carpio; Epigenetics

Educación

  •  Ciencias, UNIVERSITE DE LIEGE. Bélgica, 2001

Experiencia Académica

  •   profesor auxiliar Other

    UNIVERSIDAD AUSTRAL DE CHILE

    Medicina

    Valdivia, Chile

    1993 - 1994

  •   Profesor Titular Full Time

    UNIVERSIDAD ANDRES BELLO

    Ecología y Recursos Naturales

    Santiago, Chile

    2001 - A la fecha


 

Article (20)

Cortisol Induces Reactive Oxygen Species Through a Membrane Glucocorticoid Receptor in Rainbow Trout Myotubes
Fish skeletal muscle tissue is an important focus of immune reactions during pathogen infection
Transcriptomic analysis of the hepatic response to stress in the red cusk-eel (Genypterus chilensis): Insights into lipid metabolism, oxidative stress and liver steatosis
RNA interference in Haliotis rufescens myostatin evidences upregulation of insulin signaling pathway
Bacterial lipopolysaccharide induces rainbow trout myotube atrophy via Akt/FoxO1/Atrogin-1 signaling pathway
Insulin-like growth factor-1 suppresses the Myostatin signaling pathway during myogenic differentiation
mRNA-seq reveals skeletal muscle atrophy in response to handling stress in a marine teleost, the red cusk-eel (Genypterus chilensis)
The TORC1/P70S6K and TORC1/4EBP1 signaling pathways have a stronger contribution on skeletal muscle growth than MAPK/ERK in an early vertebrate: Differential involvement of the IGF system and atrogenes
Transcriptional dynamics of immune, growth and stress related genes in skeletal muscle of the fine flounder (Paralichthys adpersus) during different nutritional statuses
Epigenetic regulation of the ribosomal cistron seasonally modulates enrichment of H2A.Z and H2A.Zub in response to different environmental inputs in carp (Cyprinus carpio)
IGF-1 induces IP3-dependent calcium signal involved in the regulation of myostatin gene expression mediated by NFAT during myoblast differentiation
Isolation and selection of suitable reference genes for real-time PCR analyses in the skeletal muscle of the fine flounder in response to nutritional status: assessment and normalization of gene expression of growth-related genes
Nutritional status modulates plasma leptin, AMPK and TOR activation, and mitochondrial biogenesis: Implications for cell metabolism and growth in skeletal muscle of the fine flounder
Regulation of skeletal muscle growth in fish by the growth hormone - Insulin-like growth factor system
The cAMP Response Element Binding protein (CREB) is activated by Insulin-like Growth Factor-1 (IGF-1) and regulates myostatin gene expression in skeletal myoblast
Transient inactivation of myostatin induces muscle hypertrophy and overcompensatory growth in zebrafish via inactivation of the SMAD signaling pathway
Catabolic Signaling Pathways, Atrogenes, and Ubiquitinated Proteins Are Regulated by the Nutritional Status in the Muscle of the Fine Flounder
Dynamic transcriptional regulation of autocrine/paracrine igfbp1, 2, 3, 4, 5, and 6 in the skeletal muscle of the fine flounder during different nutritional statuses
Inherent Growth Hormone Resistance in the Skeletal Muscle of the Fine Flounder Is Modulated by Nutritional Status and Is Characterized by High Contents of Truncated GHR, Impairment in the JAK2/STAT5 Signaling Pathway, and Low IGF-I Expression
Plasma leptin and growth hormone levels in the fine flounder (Paralichthys adspersus) increase gradually during fasting and decline rapidly after refeeding

Abstract (1)

Analysis of the epigenetic response induced by environmental conditions during seasonal adaptation of C. carpio fish

Errata (1)

Nutritional status modulates plasma leptin, AMPK and TOR activation, and mitochondrial biogenesis: Implications for cell metabolism and growth in skeletal muscle of the fine flounder (vol 186, pg 172, 2013)

Proyecto (6)

Analysis of the epigenetic regulation in the ribosomal cistron induced by environmental stimuli in cyprinus carpio fish
Challenging the stress response paradigm in fish: role of cortisol membrane-initiated signaling in metabolic adaptations of skeletal muscle.
Effect of chronic stress response triggered by fish farming conditions on endocrine and molecular signaling pathways involved in muscle growth in the fine flounder.
Interdisciplinary Center for Aquaculture Research (INCAR)
Pathogen-induced immune-like response of fish skeletal muscle: stress-induced immunosuppression and growth impairment
Rol del tratamiento con PAMPs y la respuesta pro-inflamatoria en la activación de las vías de señalización de atrofia del músculo esquelético en trucha arcoíris (Oncorhynchus mykiss)
28
Alfredo Molina

UNIVERSIDAD ANDRES BELLO

SANTIAGO, Chile

19
Juan Valdés

Head lab

Ciencias Biologicas

UNIVERSIDAD ANDRÉS BELLO

Santiago, Chile

6
Eduardo Fuentes

Founder and CEO

BioPub

santiago, Chile

4
Jorge Aedo

Asistente de Investigación

Ciencias Biológicas

Universidad Andrés Bello

Santiago, Chile

4
Cristian Gallardo

Profesor Asociado

Departamento de Oceanografía

Universidad de Concepción

Concepcion, Chile

3
Marco Alvarez

Full Professor

Department of Biological Science

Universidad Andres Bello

Viña del Mar, Chile

2
Juan Manuel Estrada

Director

Facultad de Ecología y Recursos Naturales

Universidad Andrés Bello

Quintay , Chile

2
Luis Mercado

Profesor Titular

Instituto de Biología

Pontificia Universidad Católica de Valparaíso

Valparaíso, Chile

2
Herman Silva

Professor

Departamento de Produccion Agricola

Universidad de Chile

Santiago, Chile

2
JONATHAN MALDONADO

Postdoc CONICYT

Dpto. Genética Molecular y Microbiología

Pontificia Universidad Católica de Chile

Santiago, Chile

2
Ruben Avendaño

Full Professor

UNIVERSIDAD ANDRÉS BELLO

Viña del Mar, Chile

2
Gino Nardocci

Investigador

Universidad de Los Andes

Santiago, Chile

2
Alvaro Elorza

ASSOCIATE PROFESSOR

INSTITUTE OF BIOMEDICAL SCIENCES

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

1
Rodolfo Paredes

Medical Education and Clinical Simulation Director

Academic Vice Rectory

UNIVERDAD ANDRÉS BELLO

Santiago, Chile

1
César Osorio

Associate Professor

Kinesiología

Universidad Metropolitana de Ciencias de la Educación

Santiago, Chile

1
Enrique Jaimovich

Full Professor

ICBM

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

1
Pamela Ruiz

Investigador

Centro de Biotecnología

Universidad de Concepción

Concepción, Chile

1
Orozimba Delgado

Profesor Asociado

Facultad de Medicina Clinica Alemana Universidad del Desarrollo

UNIVERSIDAD DEL DESARROLLO

Santiago, Chile

1
Ariel Reyes

Director de Departamento

Ciencias Biológicas

UNIVERSIDAD ANDRÉS BELLO

Santiago, Chile

1
Matías Poblete

Investigador

Instituto de Ciencias Biomédicas

Universidad Autónoma de Chile

Santiago, Chile

1
Claudio Meneses

Profesor Titular

Facultad de Ciencias de la Vida

UNIVERSIDAD ANDRÉS BELLO

Santiago, Chile