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Valentina Marjorie Valenzuela Muñoz

Investigador Asociado

Universidad de Concepción

Concepción, Chile

Genomica, Inmunología, Acuicultura

Bioquimica y Bioinformatica, UNIVERSIDAD DE CONCEPCION. Chile, 2011
Manejo de Recursos Marinos Renovables, UNIVERSIDAD DE CONCEPCION. Chile, 2018
Ingeniero en Biotecnologia, UNIVERSIDAD SAN SEBASTIAN. Chile, 2009

Docente Investigadora Full Time

Universidad San Sebastian

Ciencias de la Naturaleza

Concepcion, Chile

2024 - A la fecha

ASISTENTE DE INVESTIGACION Full Time

UNIVERSIDAD DE CONCEPCION

CONCEPCION, Chile

2010 - 2012
ASISTENTE DE INVESTIGACION Part Time

UNIVERSIDAD DE CONCEPCION

CONCEPCION, Chile

2013 - 2018
Investigador Asociado Part Time

Interdisciplinary Center for Aquaculture Research

Concepción, Chile

2019 - A la fecha
Investigadora Part Time

Centro Copas Costal

Concepcion, Chile

2022 - A la fecha

Co-tutoria de tesis de pre-grado carrera: Ingenieria en Biotecnologia Marina y Aquicultura-Universidad de Concepción; Titulo de tesis: Efecto de ferritina recombinante sobre la modulacion del metabolismo de hierro y el sistema inmune de salmón del Atlántico; Alumna: Camila Riquelme; año:2017

Co-tutoria de tesis de pre-grado carrera: Ingenieria en Biotecnologías-Universidad Andres Bello; Titulo de tesis: “Evaluación del efecto de cortisol mediado por receptores de superficie celular sobre la vía de adhesión focal en trucha arcoíris (Oncorhynchus mykiss).”; Alumna:Carla Soto; año 2020.

Participación en programa Experimenta, ciencia de niños (https://www.youtube.com/watch?v=7SRiCcZio6A)


Environmental influence on the Atlantic salmon transcriptome and methylome during sea lice infestations Wanamaker, Shelly; Garcia, Ana Article ISI FISH & SHELLFISH IMMUNOLOGY (2024)
Hypoxia in the Blue Mussel Mytilus chilensis Induces a Transcriptome Shift Associated with Endoplasmic Reticulum Stress, Metabolism, and Immune Response Montufar-Romero, Milton Article ISI SCOPUS Genes (2024)
The Atlantic salmon microbiome infected with the sea louse Caligus rogercresseyi reveals tissue-specific functional dysbiosis Munoz-Trorcoso, Marcelo; Muñoz-Troncoso, Marcelo Article ISI SCOPUS AQUACULTURE (2024)
Transcriptomic and Epigenomic Responses to Cortisol-Mediated Stress in Rainbow Trout (<i>Oncorhynchus mykiss</i>) Skeletal Muscle Molina, Alfredo Article ISI INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2024)
Alternative splicing in Atlantic salmon head kidney and SHK-1 cell line during the Piscirickettsia salmonis infection: A comparative transcriptome survey Article ISI FISH & SHELLFISH IMMUNOLOGY (2023)
Comparative Transcriptomics in Atlantic Salmon Head Kidney and SHK-1 Cell Line Exposed to the Sea Louse Cr-Cathepsin Article ISI GENES (2023)
High-Temperature Stress Induces Autophagy in Rainbow Trout Skeletal Muscle Article ISI SCOPUS Fishes (2023)
Transcriptome Signatures of Atlantic Salmon-Resistant Phenotypes against Sea Lice Infestation Are Associated with Tissue Repair Alert, Alejandro Article ISI SCOPUS Genes (2023)
Competing endogenous RNA-networks reveal key regulatory microRNAs involved in the response of Atlantic salmon to a novel orthomyxovirus Article ISI DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY (2022)
Dual RNA-Seq Analysis Reveals Transcriptome Effects during the Salmon-Louse Interaction in Fish Immunized with Three Lice Vaccines Article ISI SCOPUS Vaccines (2022)
Peritrophin-like Genes Are Associated with Delousing Drug Response and Sensitivity in the Sea Louse Caligus rogercresseyi Article ISI INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)
Whole-Genome Transcript Expression Profiling Reveals Novel Insights into Transposon Genes and Non-Coding RNAs during Atlantic Salmon Seawater Adaptation Article ISI SCOPUS Biology (2022)
Chimeric Protein IPath(R) with Chelating Activity Improves Atlantic Salmon's Immunity against Infectious Diseases Article ISI VACCINES (2021)
The wastewater microbiome: A novel insight for COVID-19 surveillance Benaventel, Barbara P.; Assmann, Paulina Article ISI SCIENCE OF THE TOTAL ENVIRONMENT (2021)
Transcriptome and morphological analysis in<i> Caligus</i><i> rogercresseyi</i> uncover the effects of Atlantic salmon vaccination with IPath® Article ISI FISH & SHELLFISH IMMUNOLOGY (2021)
Transcriptome Profiling of Long Non-coding RNAs During the Atlantic Salmon Smoltification Process Article ISI SCOPUS MARINE BIOTECHNOLOGY (2021)
Transcriptomic analysis reveals a Piscirickettsia salmonis-induced early inflammatory response in rainbow trout skeletal muscle Carrizo, Victoria; Molina, Alfredo Article ISI COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY D-GENOMICS & PROTEOMICS (2021)
Induced?iron overdose modulate the immune response in Atlantic salmon increasing the susceptibility to Piscirickettsia salmonis infection Article ISI SCOPUS (2020)
More than bubbles: In vivo assessment and transcriptome modulation of Caligus rogercresseyi and Atlantic salmon exposed to hydrogen peroxide (PARAMOVE®) Gallardo-EscÃ¡rate A.; SÃ¡ez-Vera C.; GarcÃ©s F.; Bonfatti J. Article ISI SCOPUS (2020)
Nanopore sequencing of microbial communities reveals the potential role of sea lice as a reservoir for fish pathogens Collipal-Matamal, Rayen Article SCOPUS SCIENTIFIC REPORTS (2020)
RNA-Seq analysis reveals that spring viraemia of carp virus induces a broad spectrum of PIM kinases in zebrafish kidney that promote viral entry Article ISI SCOPUS (2020)
Comparative modulation of lncRNAs in wild-type and rag1-heterozygous mutant zebrafish exposed to immune challenge with spring viraemia of carp virus (SVCV) Álvarez-Rodríguez M. Article ISI SCOPUS Scientific Reports (2019)
Comparative analysis of long non-coding RNAs in Atlantic and Coho salmon reveals divergent transcriptome responses associated with immunity and tissue repair during sea lice infestation Article ISI SCOPUS DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY (2018)
Comparative analysis of long non-coding RNAs in Atlantic and Coho salmon reveals divergent transcriptome responses associated with immunity and tissue repair during sea lice infestation Valenzuela-Muñoz, Valentina Valenzuela-Miranda; Diego Gallardo-Escápate, Cristian Article DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY (2018)
Metagenomic study of bacterial microbiota in persistent endodontic infections using Next-generation sequencing Valenzuela, V. Article ISI SCOPUS International Endodontic Journal (2018)
De novo transcriptome analysis of the red seaweed Gracilaria chilensis and identification of linkers associated with phycobilisomes Vorphal,M.A. Gallardo-Escápate; C. Valenzuela-Muñoz,V. Dagnino-Leone; J. Aleikar Vásquez,J. Martínez-Oyaneder; J. Munster, M. Article Marine Genomics (2017)
Intestinal transcriptome modulation by functional diets in rainbow trout=> A high-throughput sequencing appraisal to highlight GALT immunomodulation Gonçalves, A. T Valenzuela-Muñoz; V Gallardo-Escápate, C Article FISH & SHELLFISH IMMUNOLOGY (2017)
Iron metabolism modulation in Atlantic salmon infested with the sea lice Lepeophtheirus salmonis and Caligus rogercresseyi=> A matter of nutritional immunity? Valenzuela-Muñoz, V. Gallardo-Escárate Article FISH & SHELLFISH IMMUNOLOGY (2017)
The Caligus rogercresseyi miRNome=> Discovery and transcriptome profiling during the sea lice ontogeny Gallardo-Escápate, C. Valenzuela-Muñoz; V. Boltaña, S. Nuñez-Acuña; G. Valenzuela-Miranda, D. Gonçalves; A.T. Detree, C. Tarifeño-Saldivia; E. Farlora, R. Roberts; S. Putnam, H.M. Article Agri Gene (2017)
Uncovering iron regulation with species-specific transcriptome patterns in Atlantic and coho salmon during a Caligus rogercresseyi infestation Valenzuela-Muñoz, V Boltaña; S. Gallardo-Escárate, C. Article JOURNAL OF FISH DISEASES (2017)
Uncovering iron regulation with species‐specific transcriptome patterns in Atlantic and coho salmon during a Caligus rogercresseyi infestation Article Journal of fFsh Diseases (2017)
Aquaporin family genes exhibit developmentally-regulated and host-dependent transcription patterns in the sea louse Caligus rogercresseyi Rodolfo Farlora; Jacqueline Mardones Article GENE (2016)
Aquaporin family genes exhibit developmentally-regulated and host-dependent transcription patterns in the sea louse Caligus rogercresseyi Farlora, R. Valenzuela-Muñoz; V. Chavez-Mardones, J. Gallardo-Escárate Article Gene (2016)
Evidence for the Induction of Key Components of the NOTCH Signaling Pathway via Deltamethrin and Azamethiphos Treatment in the Sea Louse Caligus rogercresseyi Boltaña S. Article ISI SCOPUS INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)
In silico transcriptome analysis of cuticle-related genes associated with delousing drug responses in the sea louse Caligus rogercresseyi Chavez-Mardones, J. Valentina Valenzuela-Muñoz; V. Gallardo-Escárate, C. Article AQUACULTURE (2016)
Iron metabolism modulation in Atlantic salmon infested with the sea lice Lepeophtheirus salmonis and Caligus rogercresseyi: A matter of nutritional immunity? Article Fish and Shellfish Immunology (2016)
Transcriptome mining=> Multigene panel to test delousing drug response in the sea louse Caligus rogercresseyi Valenzuela-Muñoz, V. Gallardo-Escárate Article Marine Genomics (2016)
RNA-seq analysis evidences multiple gene responses in Caligus rogercresseyi exposed to the anti-salmon lice drug azamethiphos Article AQUACULTURE (2015)
SNP discovery and gene annotation in the surf clam Mesodesma donacium Gallardo-Escárate, C Valenzuela-Muñoz; V. Núñez-Acuña, G Haye Article AQUACULTURE RESEARCH (2015)
Transcription expression of immune-related genes from Caligus rogercresseyi evidences host-dependent patterns on Atlantic and coho salmon. Vera-Bizama, F. Valenzuela-Muñoz; V. Gonçalvez, A. T. Pino Marambio; J. Hawes, C. Wadsworth; S. Gallardo-Escárate, C. Article FISH & SHELLFISH IMMUNOLOGY (2015)
Transcriptome immunomodulation of in-feed additives in Atlantic salmon Salmo salar infested with sea lice Caligus rogercresseyi Núñez-Acuña, G. Gonçalves; AT Valenzuela-Muñoz, V. Pino Marambio; J. Wadsworth, S. Gallardo-Escápate Article FISH & SHELLFISH IMMUNOLOGY (2015)
Transcriptomic insights on the ABC transporter gene family in the salmon louse Caligus rogercresseyi Armin Sturm Article Parasites and Vectors (2015)
Characterization of the transcriptomes of Haliotis rufescens reproductive tissues Valenzuela-Muñoz, Valentina; Bueno-Ibarra, Mario A.; Escárate, Cristian Gallardo Article ISI SCOPUS AQUACULTURE RESEARCH (2014)
High-throughput SNP discovery and transcriptome expression profiles from the salmon louse Caligus rogercresseyi (Copepoda: Caligidae) Núñez-Acuña, Gustavo; Valenzuela-Muñoz, Valentina; Gallardo-Escárate, Cristian Article ISI COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY D-GENOMICS & PROTEOMICS (2014)
Insights into the olfactory system of the ectoparasite Caligus rogercresseyi: Molecular characterization and gene transcription analysis of novel ionotropic receptors Núñez-Acuña, Gustavo; Valenzuela-Muñoz, Valentina; Marambio, Jorge Pino; Wadsworth, Simon; Gallardo-Escárate, Cristian Article ISI EXPERIMENTAL PARASITOLOGY (2014)
Insights into the olfactory system of the ectoparasite Caligus rogercresseyi=> Molecular characterization and gene transcription analysis of novel ionotropic receptors. Núñez-Acuña, G. Valenzuela-Muñoz; V. Pino Marambio, J. Wadsworth; S. Gallardo-Escárate, C. Article EXPERIMENTAL PARASITOLOGY (2014)
Pathogenic role of BECN1/Beclin 1 in the development of amyotrophic lateral sclerosis Nassif, M; Valenzuela, V.; Rojas-Rivera, D; Vidal, R; Matus, S; Castillo, K; Fuentealba Y.; Kroemer G.; Levine, B; Hetz C. Article ISI SCOPUS AUTOPHAGY (2014)
RNA-Seq Analysis Using De Novo Transcriptome Assembly as a Reference for the Salmon Louse Caligus rogercresseyi Gallardo-Escárate, Cristian; Valenzuela-Muñoz, Valentina; Núñez-Acuña, Gustavo; Gibas, Cynthia Article ISI SCOPUS PloS one (2014)
RNA-seq analysis using de novo transcriptome assembly as a reference for the salmon louse Caligus rogercresseyi. Gallardo-Escárate, C. Valenzuela-Muñoz; V. Núñez-Acuña, G. Article PLoS One (2014)
Sprouting of axonal collaterals after spinal cord injury is prevented by delayed axonal degeneration Collyer, E.; Catenaccio, A; Lemaitre D.; Díaz P; Valenzuela, V.; Bronfman, F; Court, F. A. Article ISI SCOPUS EXPERIMENTAL NEUROLOGY (2014)
Concholepas concholepas Ferritin H-like subunit (CcFer)=> molecular characterization and single nucleotide polymorphism associated to innate immune response Chávez-Mardones, J. Valenzuela-Muñoz; V. Núñez-Acuña, G. Maldonado - Aguayo; W. Cristian Gallardo-Escárate, C Article FISH & SHELLFISH IMMUNOLOGY (2013)
SNP discovery in the marine gastropod Concholepas concholepas by high-throughput transcriptome sequencing. Gallardo-Escárate, C. Núñez-Acuña; G. Valenzuela-Muñoz, v. Article Conservation Genetics Resources (2013)


Protein disulfide isomerase gene variants are associated with amyotrophic lateral sclerosis Woehlbier, U; Gonzalez-Perez, P; Colombo, A; Saaranen MJ.,; Bustos F.; Lopez-Gonzalez, R; Ojeda J.; Perez, V.; Valenzuela, V.; Medinas D; et al. Abstract ISI FEBS JOURNAL (2014)
HALIOTIS RUFESCENS X H. DISCUS HANNAI: A NEW HYBRID TO IMPROVE THE CHILEAN ABALONE AQUACULTURE? Lafarga-De la Cruz, F; Amar-Basulto, G; Nunez-Acuna, G; Valenzuela, V.; Gallardo-Escarate, C Abstract ISI JOURNAL OF SHELLFISH RESEARCH (2012)


The race between host and sea lice in the Chilean salmon farming: a genomic approach GonÃ§alves A.T.; NuÃ±ez-AcuÃ±a G.; Valenzuela-MuÃ±oz V. ConferencePaper ISI SCOPUS REVIEWS IN AQUACULTURE (2019)
Effects of uneven mass distribution on plasma dynamics in cylindrical wire array Z-pinches Veloso F.; Donoso L; Swadling, G; Chittenden, J; Muñoz, G; Valenzuela, V.; Suzuki-Vidal, F; Favre, M.; Wyndham E. ConferencePaper ISI SCOPUS Journal of Physics: Conference Series (2015)
Plasma Formation And Dynamics In Conical Wire Arrays In The Llampudken Pulsed Power Generator Muñoz, G; Valenzuela, V.; Veloso F.; Favre, M.; Wyndham E. ConferencePaper ISI SCOPUS LATIN AMERICAN SCHOOL OF PHYSICS MARCOS MOSHINSKY (ELAF2017) - QUANTUM CORRELATIONS (2014)


Sex-Biased Transcription Expression of Vitellogenins Reveals Fusion Gene and MicroRNA Regulation in the Sea Louse <i>Caligus rogercresseyi</i> Letter ISI MARINE BIOTECHNOLOGY (2024)


Modelo para la evaluación y optimización de procesos de remediación de ambientes marinos alterados por acuicultura Proyecto (2024)
INTERDISCIPLINARY CENTER FOR AQUACULTURE RESEARCH (INCAR) Proyecto (2023)
Functional genomics in Atlantic salmon during repeated sea lice infestations: the emerging role of acquired resistance in salmón breeding Proyecto (2022)
Center for Oceanographic Research in the eastern South Pacific, COPAS Sur-Austral (COASTAL) Proyecto (2021)
Dancing with the genes: the role of topologically associated domains (TADs) to drive the non-coding/coding RNA interactions in sea lice biology Valentina Valezuela-Muñoz Proyecto (2021)
Functional genomics applied to parr-smolt transformation: novel biomarkers for smolt selection in Atlantic salmon Proyecto (2019)
Generación de vacuna inhibitoria de Miostatina (MSTN) para incrementar el crecimiento de abalones rojo como estrategia de mejoramiento CORFO (12IDL2-15119) Proyecto 2013-2015 Coinvestigador(a)
Biotecnología aplicada a la producción de un híbrido entre abalón rojo y verde (Fase 2)=> Optimización del procedimiento de cruza para el desarrollo de una variedad de interés productivo y comercial FONDEF (D09I1067) Proyecto 2011-2013 Personal técnico y/o de apoyo
Producción de abalones monosexo mediante inactivación nuclear gamética y desarrollo de una técnica para la identificación sexual=> Soluciones biotecnológicas para la industria del abalón FONDEF (D07I1085) Proyecto 2009-2010 Personal técnico y/o de apoyo
Biotecnología aplicada a la producción de un híbrido entre abalón rojo y verde=> desarrollo de un nuevo producto y prospección del mercado consumidor FONDEF (D06I1027) Proyecto 2008-2009 Personal técnico y/o de apoyo


Modulation of Atlantic salmon miRNome response to sea louse infestation Review ISI SCOPUS DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY (2017)

Francisca Bronfman

Full Professor

Instituto de Ciencias Biomédicas

Universidad Andrés Bello

Santiago, Chile

Cristian Gallardo

Profesor Titular

Departamento de Oceanografía

Universidad de Concepción

Concepcion, Chile

Gerardo Gonzalez

Full Professor

Microbiology

UNIVERSIDAD DE CONCEPCION

Concepcion, Chile

Alfredo Molina

UNIVERSIDAD ANDRES BELLO

SANTIAGO, Chile

Homero Urrutia

Profesor titular

Facultad de Ciencias Biológicas

UNIVERSIDAD DE CONCEPCIÓN

Concepción, Chile

Claudio Hetz

Deputy Director

INSTITUTO DE CIENCIAS BIOMÉDICAS, FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

SANTIAGO, Chile

Alicia Colombo

Profesora Asociada/Director Científico Biobanco de Tejidos y Fluidos de la Universidad de Chile

Departamento de Anatomía Patológica

Universidad de Chile

Santiago, Chile

Juan Valdés

Head lab

Ciencias Biológicas

UNIVERSIDAD ANDRÉS BELLO

Santiago, Chile

Mario Favre

Profesor Titular

Instituto de Física, Pontificia Universidad Católica de Chile

Santiago, Chile

Ricardo Armisen

Associate Professor

Centro de Genética y Genómica

Universidad del Desarrollo

Santiago, Chile

Felipe Veloso

Profesor Asociado

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

Claudia Altamirano

Profesor Titular

Facultad de Ingeniería

PONTIFICIA UNIVERSIDAD CATOLICA DE VALPARAISO

Valparaíso, Chile

René Vidal

Profesor Asociado

Universidad Mayor

Santiago, Chile

Karen Castillo

Académica Investigadora

,Centro de Investigación de Estudios Avanzados del Maule (CIEAM)

Universidad Catolica del Maule

Talca, Chile

Diego Rojas

Assistant Professor

Center for Integrative Biology

Universidad Mayor

Santiago, Chile

Sebastian Boltana

Profesor Asociado

Occeanografia

Universidad de Concepcion

Concpecion, Chile

Felipe Court

Full Professor and Director

Center for Integrative Biology

Universidad Mayor

Huechuraba, Chile

Melissa Calegaro

Principal Investigator, head lab

Research Vice Presidency

Universidad Mayor

Santiago, Chile

Phillip Dettleff

Profesor asistente

Escuela de Medicina Veterinaria, Pontificia Universidad Católica de Chile

Santiago, Chile

Diego Valenzuela

PostDoc

Universidad de Concepción

Concepción, Chile

Valentina Valenzuela

Investigador Asociado

Centro de Biotecnologia

Universidad de Concepción

Concepción, Chile

Alfredo Sagredo

Investigador Postdoctoral

ICBM

Universidad de Chile

Santiago, Chile

Alejandra Catenaccio

Asistente de Investigación

Universidad Mayor

HUECHURABA, SANTIAGO, Chile

Ute Wohlbier

Associate Professor

Center for Integrative Biology

Universidad Mayor de Chile

Santiago, Chile

Maria Matus

Principal Investigator

Fundacion Ciencia & Vida

Santiago, Chile

GABRIELA SANCHEZ

Profesor Asociado

Odontología Restauradora

Universidad de Concepción

Concepción, Chile

Gustavo Núñez

Investigador Postdoctoral

Vicerrectoría de Investigación y Desarrollo

Universidad de Concepción

Concepción, Chile

Paula Diaz

PhD (c)

Departamento de Fisiología

Pontificia Universidad Católica de Chile

Santiago, Chile

Viviana Pérez

Profesor Asistente

Fisiología

Universidad de Concepción

Concepcion, Chile

Yeny Leal

Investigadora Postdoctoral

Laboratorio de Biotecnología y Genómica Acuícola

Universidad de Concepción

Concepción, Chile

Antonio Casuso

Postdoctorado

Centro de Biotecnología, Universidad de Concepción

Concepción, Chile

Valentina Marjorie Valenzuela Muñoz

Líneas de Investigación

Educación

Bioquimica y Bioinformatica, UNIVERSIDAD DE CONCEPCION. Chile, 2011

Manejo de Recursos Marinos Renovables, UNIVERSIDAD DE CONCEPCION. Chile, 2018

Ingeniero en Biotecnologia, UNIVERSIDAD SAN SEBASTIAN. Chile, 2009

Experiencia Académica

Docente Investigadora Full Time

Experiencia Profesional

ASISTENTE DE INVESTIGACION Full Time

ASISTENTE DE INVESTIGACION Part Time

Investigador Asociado Part Time

Investigadora Part Time

Formación de Capital Humano

Difusión y Transferencia

Article (52)

Abstract (2)

ConferencePaper (3)

Letter (1)

Proyecto (10)

Generación de vacuna inhibitoria de Miostatina (MSTN) para incrementar el crecimiento de abalones rojo como estrategia de mejoramiento

Biotecnología aplicada a la producción de un híbrido entre abalón rojo y verde (Fase 2)=> Optimización del procedimiento de cruza para el desarrollo de una variedad de interés productivo y comercial

Producción de abalones monosexo mediante inactivación nuclear gamética y desarrollo de una técnica para la identificación sexual=> Soluciones biotecnológicas para la industria del abalón

Biotecnología aplicada a la producción de un híbrido entre abalón rojo y verde=> desarrollo de un nuevo producto y prospección del mercado consumidor

Review (1)