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Diego Andrés Valenzuela Miranda

PostDoc

Universidad de Concepción

Concepción, Chile

Enfoque hologenómico aplicado a la acuicultura de peces e invertebrados, Genética y genómica de organismos marinos

Doctorado en Ciencias con mención en Manejo de Recursos Acuáticos Renovables, UNIVERSIDAD DE CONCEPCION. Chile, 2019

Investigador Responsable Full Time

FONDECYT Postdoc

Untangling the sea lice microbiome: A potential threat for Chilean salmon farming

Chile

2020 - 2023
Investigador asociado Other

Centro de Biotecnologia

Chile

2022 - A la fecha
Investigador Adjunto Full Time

Centro INCAR

Chile

2020 - A la fecha

asistente de investigación Full Time

universidad de concepción

Chile

2013 - 2019


Chromosome-Level Genome Assembly of the Blue Mussel Mytilus chilensis Reveals Molecular Signatures Facing the Marine Environment Gallardo-Escarate, Cristian; Valenzuela-Munoz, Valentina; Nunez-Acuna, Gustavo; Valenzuela-Miranda, Diego; Tapia, Fabian J.; Yevenes, Marco; Gajardo, Gonzalo; Toro, Jorge E.; Oyarzun, Pablo A.; Arriagada, Gloria; Novoa, Beatriz; Figueras, Antonio; Roberts, Steven; Gerdol, Marco Article ISI GENES (2023)
Transcriptome Signatures of Atlantic Salmon-Resistant Phenotypes against Sea Lice Infestation Are Associated with Tissue Repair Valenzuela-Munoz, Valentina; GALLARDO-ESCARATE, CRISTIAN JORGE; Valenzuela-Miranda, Diego; NUNEZ-ACUNA, GUSTAVO IGNACIO; Benavente, Barbara P.; Alert, Alejandro; Arevalo, Marta Article ISI SCOPUS Genes (2023)
Whole-genome resequencing in the sea louse <i>Caligus rogercresseyi</i> uncovers gene duplications and copy number variants associated with pesticide resistance NUNEZ-ACUNA, GUSTAVO IGNACIO; Saez-Vera, Constanza; Valenzuela-Miranda, Diego; Valenzuela-Munoz, Valentina; GALLARDO-ESCARATE, CRISTIAN JORGE Article ISI SCOPUS Frontiers in Marine Science (2023)
Author Correction: Proximity ligation strategy for the genomic reconstruction of microbial communities associated with the ectoparasite Caligus rogercresseyi (Scientific Reports, (2022), 12, 1, (783), 10.1038/s41598-021-04485-0) Valenzuela-Miranda, Diego; Goncalves, A. T.; Valenzuela-Munoz, Valentina; NUNEZ-ACUNA, GUSTAVO IGNACIO; Liachko, Ivan; Nelson, Bradley; Gallardo-Escarate, Cristian Article SCOPUS SCIENTIFIC REPORTS (2022)
Competing endogenous RNA-networks reveal key regulatory microRNAs involved in the response of Atlantic salmon to a novel orthomyxovirus SAMSING-PEDRALS, FRANCISCA; Wynne, James W.; Valenzuela-Munoz, Valentina; Valenzuela-Miranda, Diego; GALLARDO-ESCARATE, CRISTIAN JORGE; Alexandre, Pâmela A. Article ISI SCOPUS DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY (2022)
Exploring Sea Lice Vaccines against Early Stages of Infestation in Atlantic Salmon (<i>Salmo salar</i>) Casuso, Antonio; Valenzuela-Munoz, Valentina; Benavente, Bárbara P.; Valenzuela-Miranda, Diego; GALLARDO-ESCARATE, CRISTIAN JORGE Article ISI SCOPUS Vaccines (2022)
Nanopore sequencing evidenced the presence of fish bacterial pathogens in the sea louse (Caligus rogercresseyi) microbiota collected from distant salmon farms in Chile Morales-Rivera, Maria F.; Valenzuela-Miranda, Diego; Valenzuela-Munoz, Valentina; Nunez-Acuna, Gustavo; Avendano-Herrera, Ruben; Gallardo-Escarate, Cristian Article ISI AQUACULTURE (2022)
Proximity ligation strategy for the genomic reconstruction of microbial communities associated with the ectoparasite Caligus rogercresseyi Valenzuela-Miranda, Diego; Teresa Goncalves, Ana; Valenzuela-Munoz, Valentina; Nunez-Acuna, Gustavo; Liachko, Ivan; Nelson, Bradley; Gallardo-Escarate, Cristian Article ISI SCIENTIFIC REPORTS (2022)
Whole-Genome Transcript Expression Profiling Reveals Novel Insights into Transposon Genes and Non-Coding RNAs during Atlantic Salmon Seawater Adaptation Valenzuela-Munoz, Valentina; GALLARDO-ESCARATE, CRISTIAN JORGE; Benavente, Bárbara P.; Valenzuela-Miranda, Diego; NUNEZ-ACUNA, GUSTAVO IGNACIO; Escobar-Sepulveda, Hugo; Valdés, Juan A. Article ISI SCOPUS Biology (2022)
Chromosome-scale genome assembly of the sea louse <i>Caligus rogercresseyi</i> by SMRT sequencing and Hi-C analysis GALLARDO-ESCARATE, CRISTIAN JORGE; Valenzuela-Munoz, Valentina; NUNEZ-ACUNA, GUSTAVO IGNACIO; Valenzuela-Miranda, Diego; Goncalves, A. T.; Escobar-Sepulveda, Hugo; Liachko, Ivan; Nelson, Bradley; Roberts, Steven; Warren, Wesley Article ISI SCOPUS SCIENTIFIC DATA (2021)
Comprehensive Transcriptome Analyses in Sea Louse Reveal Novel Delousing Drug Responses Through MicroRNA regulation NUNEZ-ACUNA, GUSTAVO IGNACIO; Valenzuela-Munoz, Valentina; Valenzuela-Miranda, Diego; GALLARDO-ESCARATE, CRISTIAN JORGE Article ISI SCOPUS MARINE BIOTECHNOLOGY (2021)
The wastewater microbiome: A novel insight for COVID-19 surveillance Gallardo-Escarate, Cristian; Valenzuela-Munoz, Valentina; Nunez-Acuna, Gustavo; Valenzuela-Miranda, Diego; Benaventel, Barbara P.; Saez-Vera, Constanza; Urrutia, Homero; Novoa, Beatriz; Figueras, Antonio; Roberts, Steven; Assmann, Paulina; Bravo, Marta Article ISI SCIENCE OF THE TOTAL ENVIRONMENT (2021)
Transcriptome and morphological analysis in<i> Caligus</i><i> rogercresseyi</i> uncover the effects of Atlantic salmon vaccination with IPath® Valenzuela-Munoz, Valentina; Benavente, Bárbara P.; Casuso, Antonio; Leal, Yeny; Valenzuela-Miranda, Diego; NUNEZ-ACUNA, GUSTAVO IGNACIO; Saez-Vera, Constanza; GALLARDO-ESCARATE, CRISTIAN JORGE Article ISI SCOPUS FISH & SHELLFISH IMMUNOLOGY (2021)
Trypsin Genes Are Regulated through the miRNA Bantam and Associated with Drug Sensitivity in the Sea Louse <i>Caligus rogercresseyi</i> NUNEZ-ACUNA, GUSTAVO IGNACIO; Valenzuela-Munoz, Valentina; Carrera-Naipil, Crisleri; Saez-Vera, Constanza; Benavente, Bárbara P.; Valenzuela-Miranda, Diego; GALLARDO-ESCARATE, CRISTIAN JORGE Article ISI SCOPUS Non-coding RNA (2021)
Induced?iron overdose modulate the immune response in Atlantic salmon increasing the susceptibility to Piscirickettsia salmonis infection Valenzuela-MuÃ±oz V.; Valenzuela-Miranda D.; GonÃ§alves A.T.; Novoa B.; Figueras A.; Gallardo-EscÃ¡rate C. Article ISI SCOPUS (2020)
Long-term serial culture of <i>Piscirickettsia salmonis</i> leads to a genomic and transcriptomic reorganization affecting bacterial virulence Valenzuela-Miranda, Diego; Valenzuela-Munoz, Valentina; NUNEZ-ACUNA, GUSTAVO IGNACIO; GALLARDO-ESCARATE, CRISTIAN JORGE Article ISI SCOPUS AQUACULTURE (2020)
Nanopore sequencing of microbial communities reveals the potential role of sea lice as a reservoir for fish pathogens Gonçalves, Ana Teresa; Collipal-Matamal, Rayen; Valenzuela-Muñoz, Valentina; Nuñez-Acuña, Gustavo; Valenzuela-Miranda, Diego; Gallardo-Escárate, Cristian Article SCOPUS SCIENTIFIC REPORTS (2020)
Tackling the Molecular Drug Sensitivity in the Sea Louse<i>Caligus rogercresseyi</i>Based on mRNA and lncRNA Interactions NUNEZ-ACUNA, GUSTAVO IGNACIO; Saez-Vera, Constanza; Valenzuela-Munoz, Valentina; Valenzuela-Miranda, Diego; ARRIAGADA-ACEVEDO, GABRIEL ALEJANDRO; GALLARDO-ESCARATE, CRISTIAN JORGE Article ISI SCOPUS Genes (2020)
Catching the complexity of salmon-louse interactions Gallardo-Escárate, Cristian; Valenzuela-Muñoz, Valentina; Núñez-Acuña, Gustavo; Carrera, Crisleri; Gonçalves, Ana Teresa; Valenzuela-Miranda, Diego; Benavente, Bárbara P.; Roberts, Steven Article ISI SCOPUS FISH & SHELLFISH IMMUNOLOGY (2019)
Comparative analysis of long non-coding RNAs in Atlantic and Coho salmon reveals divergent transcriptome responses associated with immunity and tissue repair during sea lice infestation Valenzuela-Munoz, V; Valenzuela-Miranda, D; Gallardo-Escarate, C Article ISI SCOPUS DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY (2018)
Dual RNA-Seq uncovers metabolic amino acids dependency of the intracellular bacterium Piscirickettsia salmonis Infecting Atlantic salmon Valenzuela-Miranda D.; Gallardo-EscÃ¡rate C. Article ISI SCOPUS FRONTIERS IN MICROBIOLOGY (2018)
In the shadow: The emerging role of long non-coding RNAs in the immune response of Atlantic salmon Tarifeño-Saldivia, E.; valenzuela-miranda, D.; Gallardo-Escárate, C. Article ISI SCOPUS DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY (2017)
Long noncoding RNAs=> Unexplored players in the drug response of the sea louse Caligus rogercresseyi Diego Valenzuela-Miranda, Kayvan Etebari; Sassan Asgari, Cristian Gallardo-Escárate Article Agrigene (2017)
MicroRNA-based transcriptomic responses of Atlantic salmon during infection by the intracellular bacterium Piscirickettsia salmonis Valenzuela-Miranda D.; Valenzuela-Muñoz V.; Farlora R.; Gallardo-Escárate C. Article ISI SCOPUS DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY (2017)
The Caligus rogercresseyi miRNome: Discovery and transcriptome profiling during the sea lice ontogeny C. Gallardo-Escáratea, V. Valenzuela-Muñoza, S. Boltañaa, G. Nuñez-Acuñaa, D. Valenzuela-Mirandaa, A.T. Gonçalvesa, C. Détréea, E. Tarifeño-Saldiviaa, R. Farlorab, S. Robertsc, H.M. Putnamd Article SCOPUS Agri Gene (2017)
Caligus rogercresseyi serine proteases: Transcriptomic analysis in response to delousing drugs treatments Valenzuela-Miranda, D; Gallardo-Escarate, C Article ISI SCOPUS AQUACULTURE (2016)
Long noncoding RNAs (lncRNAs) dynamics evidence immunomodulation during ISAV-Infected Atlantic salmon (Salmo salar) Boltaña S.; Valenzuela?Miranda, D; Aguilar, A; MacKenzie, S.; Gallardo-Escarate, C Article ISI SCOPUS SCIENTIFIC REPORTS (2016)
Novel insights into the response of Atlantic salmon (Salmo salar) to Piscirickettsia salmonis: Interplay of coding genes and lncRNAs during bacterial infection Valenzuela-Miranda, D; Gallardo-Escarate, C Article ISI SCOPUS FISH & SHELLFISH IMMUNOLOGY (2016)
Characterization of the growth-related transcriptome in California red abalone (Haliotis rufescens) through RNA-Seq analysis Valenzuela?Miranda, D; Del Rio-Portilla, MA; Gallardo-Escarate, C Article ISI SCOPUS Marine Genomics (2015)
From the viral perspective: Infectious salmon anemia virus (ISAV) transcriptome during the infective process in Atlantic salmon (Salmo salar) Valenzuela?Miranda, D; Cabrejos, ME; Yanez, JM; Gallardo-Escarate, C Article ISI SCOPUS Marine Genomics (2015)
High-throughput transcriptome analysis of ISAV-infected Atlantic salmon Salmo salar unravels divergent immune responses associated to head-kidney, liver and gills tissues Valenzuela?Miranda, Diego; Boltaña, Sebastian; Cabrejos, Maria E.; Yáñez, José M.; Gallardo-Escárate, Cristian Article ISI SCOPUS Fish & Shellfish Immunology (2015)
Identification of microRNAs Associated With Sexual Maturity in Rainbow Trout Brain and Testis Through Small RNA Deep Sequencing Farlora, R; Valenzuela?Miranda, D; Alarcon-Matus, P; Gallardo-Escarate, C Article ISI SCOPUS Molecular Reproduction and Development (2015)
MicroRNA biogenesis pathway from the salmon louse (Caligus rogercresseyi): Emerging role in delousing drug response Valenzuela?Miranda, D; Nunez-Acuna, G; Valenzuela-Munoz, V; Asgari S.; Gallardo-Escarate, C Article ISI SCOPUS GENE (2015)
Caligus-SEQ=> Avances, desafíos y perspectivas sobre proyecto de secuenciación masiva de última generación en Caligus rogercresseyi Cristian Gallardo-Escárate, Valentina Valenzuela-Muñoz; Gustavo Nuñez-Acuña, Jacqueline Cahvez-Mardones; Waleska Maldonado-Aguayo, Ana Gonçalvez; Rodolfo Farlora, Diego Valenzuela-Miranda Article Versión diferente (2014)
Sex-dependent transcriptome analysis and single nucleotide polymorphism (SNP) discovery in the brine shrimp Artemia franciscana Valenzuela?Miranda, D; Gallardo-Escarate, C; Valenzuela-Munoz, V; Farlora, R; Gajardo, G. Article ISI SCOPUS MARINE GENOMICS (2014)


Genomics for the understanding of the host-pathogen interaction: the case of the Atlantic salmon and Piscirickettsia salmonis Valenzuela-Miranda, D; Gallardo-Escarate, C Abstract ISI FISH & SHELLFISH IMMUNOLOGY (2019)
Iron overload alters the immune response in Atlantic salmon and increases the susceptibility to Piscirickettsia salmonis infection Valenzuela-Munoz, V; Valenzuela-Miranda, D; Gallardo-Escarate, C Abstract ISI FISH & SHELLFISH IMMUNOLOGY (2019)


The race between host and sea lice in the Chilean salmon farming: a genomic approach Gallardo-EscÃ¡rate C.; Arriagada G.; Carrera C.; GonÃ§alves A.T.; NuÃ±ez-AcuÃ±a G.; Valenzuela-Miranda D.; Valenzuela-MuÃ±oz V. ConferencePaper ISI SCOPUS REVIEWS IN AQUACULTURE (2019)


Centro Interdisciplinario para la Investigación Acuícola (INCAR) FONDAP (15110027) Proyecto 2012-2017 Investigador(a)
Desarrollo y Validación de un Chip de Snps para la Determinación de las Bases Moleculares y el Mejoramientogenético de la Resistencia a Enfermedades en Samo Salar Innovación Empresarial Individual de (INNOVA-CORFO) (2011-12843-INNOVA_PRODUCCION2011-12843) Proyecto 2012-2015 Personal técnico y/o de apoyo
Insights into innate immune response of bivalves challenged to Alexandrum catenella=> Comparative transcriptome analysis by 454 pyrosequencing FONDECYT (1120397) Proyecto 2012-2015 Tesista
Reducción del impacto de enfermedades en la industria salmonera=> sistema de evaluación y monitoreo de su condición sanitaria Innovación Empresarial Individual de (INNOVA-CORFO) (2009-6682-INNOVA_PRODUCCION2009-6682) Proyecto 2010-2013 Personal técnico y/o de apoyo