Man

Sebastian Boltana Harms

Profesor Asociado

Universidad de Concepcion

Concpecion, Chile

Líneas de Investigación


My work combines concepts and experimentation from network modelling, transcriptomics, behavioural testing and immune and neural activation studies to identify gene complexes involved in signalling, sensing and processing within the immune system

Educación

  •  Comparative Immunology, UNIVERSIDAD AUTONOMA DE BARCELONA. España, 2011
  •  Aquaculture, UNIVERSIDAD AUTONOMA DE BARCELONA. España, 2008
  •  Biologo Marino, UNIVERSIDAD CATOLICA DEL NORTE. Chile, 2004
  •  Licenciado en Ciencias del Mar, UNIVERSIDAD CATOLICA DEL NORTE. Chile, 2001

Experiencia Académica

  •   Assistant professor Full Time

    University of Stirling

    Natural Sciences

    Stirling, Reino Unido

    2013 - A la fecha

  •   Assistant professor Full Time

    UNIVERSIDAD AUTONOMA DE BARCELONA

    Faculty of Biosciences

    Barcelona, España

    2008 - 2012

  •   Profesor Asociado Full Time

    Universidad de Concepcion

    Cs. Naturales y Oceanograficas

    Concepcion, Chile

    2014 - A la fecha

Experiencia Profesional

  •   Impact Research Fellowship Full Time

    University of Stirling

    Stirling, Reino Unido

    2012 - 2014

  •   Post-­doctoral research. Full Time

    Institute of Biotechnology and Biomedicine IBB

    Barcelona, España

    2011 - 2012

  •   Research assistant. Full Time

    Universitat Autònoma de Barcelona

    Cerdanyola, Barcelona, Chile

    2007 - 2011

  •   Research assistant Full Time

    Universidad Católica del Norte

    Coquimbo, Chile

    2001 - 2004

  •   Profesor Asociado Full Time

    Universidad de Concepción

    Concepcion, Chile

    2015 - A la fecha

Formación de Capital Humano


I am an advocate of collaborative science and active discussion of scientific principles. I have always taken a great interest in people who work within my research team and strive to create a supportive and challenging environment for both undergraduate and graduate students. At this time I have completed 6 PhD theses as co-tutor and 6 MSc theses also as co-tutor. I currently have two PhD student. I also actively encourage undergraduate students to participate in our activities and usually we have 1-2 undergrads/year. I have complete 4 pre-grade theses as tutor and one as co-tutor. I would describe myself as a highly motivated and open-minded person and greatly enjoy passing this on to others.


Difusión y Transferencia


Class: Speech
Issue: Charla Inaugural Año Académico 2015/ Alumnos y Docentes de Ing. Biotec. Marina y Acuicultura
Place: University of Concepción, Concepción
Date: 2015 March

Class: Speech
Issue: Vinculación con el Class y Postgrados/ Alumnos y Docentes Fac. Cs Naturales y Oceanográficas
Place: University of Concepción, Concepción
Date: 2016 August

Class: Speech
Issue: Jornadas de clase de capacitación docente/ Docentes de enseñanza media
Place: Concepción School, Concepción
Date: 2016 June

Class: Speech
Issue: Algas Rojas Nocivas?/ I Jornadas Científicas para escolares
Place: Italian School, Concepción
Date: 2015 June

Class: Speech
Issue: Fotosíntesis y el Mar/II Jornadas Científicas para escolares
Place: Italian School, Concepción
Date: 2016 June

Class: Speech
Issue: Mini charlas científicas “PechaKucha” Nuevos jugadores en un viejo juego: el efecto de la temperatura en nuestro mar/ XXIII Semana Nacional de la Ciencia y la Tecnología
Place: Explora BioBio, Concepción
Date: 2017 October
Magazine: Science (DOI: 10.1126/science.aad7486.)
Issue: Fish show signs of sentience in ‘emotional fever’ tes (2015)

Web: PHYS.ORG
Issue: Study suggests fish can experience 'emotional fever (2015)
Link: http://phys.org/news/2015-11-fish-emotional-fever.html
Web: (e) Science New
Issue: Fish show signs of sentience in ‘emotional fever’ test (2015)
Link:http://esciencenews.com/sources/science.now/2015/11/24/fish.show.signs.sentience.emotional.fever.test
Web: Wired
Issue: Fish have emotional responses that indicate sentience (2015)
Link: http://www.wired.co.uk/article/fish-have-emotional-responses-that-indicate-sentience
Web: Wired
Issue: Fish show signs of-sentience in emotional fever test (2015)
Link: http://www.tutuz.com/fish-show-signs-of-sentience-in-emotional-fever-test/

TV Show: BBC
Issue: How do we know whether fish have feeling too? (2016)
Link: http://www.bbc.com/earth/story/20160220-do-fish-have-feelings
TV show: TVN
Issue: Ciencia en la región del Bío Bío (2017)
Link: https://www.youtube.com/watch?v=NWXE96JeMbs

Newspaper: LA VANGUARDIA
Issue: Los peces podrían tener emociones y conciencia (2015)
Link: http://www.lavanguardia.com/vida/20151127/30435003776/peces-emociones-conciencia.html
Newspaper: LA SEGUNDA
Issue: Fotoperiodo artificial apalanca el desarrollo de la acuicultura (2018)
Link: http://impresa.lasegunda.com/2018/07/20/A
Newspaper: EL MERCURIO
Issue: La Biotecnología otorga soluciones frente a los impactos del cambio climático. (2018)
Link: https://digital.elmercurio.com/2018/12/17/C/453H2LSN#zoom=page-width


Premios y Distinciones

  •   Impact Research Fellow

    UNIVERSITY OF STIRLING

    Reino Unido, 2012

    Herd protection a global approach toward understanding the mechanisms underpinning a successful response to pathogen invasion

  •   Extraordinary Award PhD Thesis

    UNIVERSIDAD AUTONOMA DE BARCELONA

    España, 2013

    Extraordinary Award PhD Thesis


 

Article (44)

Interferon gamma induces the increase of cell-surface markers (CD80/86, CD83 and MHC-II) in splenocytes from Atlantic salmon
Linking stress coping styles with brain mRNA abundance of selected transcripts for Senegalese sole (Solea senegalensis) juveniles
Characterization of the European Sea Bass (Dicentrarchus labrax) Gonadal Transcriptome During Sexual Development
Early transcriptomic responses associated with the membrane-initiated action of cortisol in the skeletal muscle of rainbow trout (Oncorhynchus mykiss)
Membrane-initiated cortisol action modulates early pyruvate dehydrogenase kinase 2 (pdk2) expression in fish skeletal muscle
Behavioral Fever Drives Epigenetic Modulation of the Immune Response in Fish
Iron Overload Is Associated With Oxidative Stress and Nutritional Immunity During Viral Infection in Fish
The expression of TRPV channels, prostaglandin E2 and pro-inflammatory cytokines during behavioural fever in fish
Thermal Modulation of Monoamine Levels Influence Fish Stress and Welfare
Behavioural fever in zebrafish larvae
Extending Immunological Profiling in the Gilthead Sea Bream, Sparus aurata, by Enriched cDNA Library Analysis, Microarray Design and Initial Studies upon the Inflammatory Response to PAMPs
Influences of thermal environment on fish growth
RNA-seq analysis of the head-kidney transcriptome response to handling-stress in the red tusk-eel (Genypterus chilensis)
The Caligus rogercresseyi miRNome: Discovery and transcriptome profiling during the sea lice ontogeny
Uncovering iron regulation with species-specific transcriptome patterns in Atlantic and coho salmon during a Caligus rogercresseyi infestation
Uncovering iron regulation with species-specific transcriptome patterns in Atlantic and coho salmon during a Caligus rogercresseyi infestation.
Comparative immunity of Salmo salar and Oncorhynchus kisutch during infestation with the sea louse Caligus rogercresseyi: An enrichment transcriptome analysis
Density-dependent effects of Caligus rogercresseyi infestation on the immune responses of Salmo salar
Evidence for the induction of key components of the NOTCH signaling pathway via deltamethrin and azamethiphos treatment in the sea louse caligus rogercresseyi
In-feed additives modulate ionotropic receptor genes from the sea louse Caligus rogercresseyi: A comparative analysis in two host salmonid species
Long noncoding RNAs (lncRNAs) dynamics evidence immunomodulation during ISAV-Infected Atlantic salmon (Salmo salar)
Pesticides Drive Stochastic Changes in the Chemoreception and Neurotransmission System of Marine Ectoparasites.
Fish can show emotional fever: stress-induced hyperthermia in zebrafish
High-throughput transcriptome analysis of ISAV-infected Atlantic salmon Salmo salar unravels divergent immune responses associated to head-kidney, liver and gills tissues
Influence of Development and Dietary Phospholipid Content and Composition on Intestinal Transcriptome of Atlantic Salmon (Salmo salar)
Investigating the underlying mechanisms of temperature-related skin diseases in Atlantic salmon, Salmo salar L., as measured by quantitative histology, skin transcriptomics and composition
Lipopolysaccharides isolated from Aeromonas salmonicida and Vibrio anguillarum show quantitative but not qualitative differences in inflammatory outcome in Sparus aurata (Gilthead seabream)
The Involvement of Cholesterol in Sepsis and Tolerance to Lipopolysaccharide Highlighted by the Transcriptome Analysis of Zebrafish ( Danio rerio )
Transcriptome Profiles Associated to VHSV Infection or DNA Vaccination in Turbot (Scophthalmus maximus)
Behavioural fever is a synergic signal amplifying the innate immune response
Combining animal personalities with transcriptomics resolves individual variation within a wild-type zebrafish population and identifies underpinning molecular differences in brain function
Effects of chronic cortisol administration on global expression of GR and the liver transcriptome in Sparus aurata.
Use of an immune-specific microarray for identifying transcriptome profiles associated to the infection of VHSV or to the protection mechanisms induced by a DNA vaccine encoding the G glycoprotein in turbot (Scophthalmus maximus)
Divergent responses to peptidoglycans derived from different E. coli serotypes influence inflammatory outcome in trout, Oncorhynchus mykiss, macrophages
Gene expression and TNF-alpha secretion profile in rainbow trout macrophages following exposures to copper and bacterial lipopolysaccharide
PAMPs, PRRs and the genomics of gram negative bacterial recognition in fish
RNA-Seq Reveals an Integrated Immune Response in Nucleated Erythrocytes
Peptidoglycan, not endotoxin, is the key mediator of cytokine gene expression induced in rainbow trout macrophages by crude LPS☆
Testing the abundant-centre hypothesis using intertidal porcelain crabs along the Chilean coast: linking abundance and life-history variation
Characterization and expression of NADPH oxidase in LPS-, poly(I:C)- and zymosan-stimulated trout (Oncorhynchus mykiss W.) macrophages
Fish can Early developmental stages of crustacean decapods associated with floating seaweed in fiord and channels from southern chileshow emotional fever: stress-induced hyperthermia in zebrafish
Geographic distribution and description of four pelagic barnacles along the south east Pacific coast of Chile - a zoogeographical approximation
Presence of sporophylls in floating kelp rafts of Macrocystis spp. (Phaeophyceae) along the Chilean Pacific Coast
Associations between two species of snapping shrimp, Alpheus inca and Alpheopsis chilensis (Decapoda : Caridea : Alpheidae)

BookSection (3)

Immune system and immune responses in rainbow trout
Developments in genomics relevant to disease control in aquaculture
Infectious disease in aquaculture

Proyecto (16)

Plataforma de análisis toxicológicos “ATOXBIO”: generación de capacidades regionales para la detección de disruptores endocrinos y otros contaminantes bioactivos con efecto en salud humana y ambiente.
To be hot or not: the underlying regulation of the immuneresponse during behavioural fever
Beyond proteins, genes and mutations=> the hidden non-coding nature of the drug resistance in sea lice
BEYOND THE GENOME=> IMPACT OF MICROBIAL COMMUNITIES FOR ADAPTATION TO NEW ENVIRONMENTS IN FISH
Challenging the stress response paradigm in fish=> role of cortisol membrane-initiated signaling in metabolic adaptations of skeletal muscle
SOME LIKE IT HOT=> THE IMPACT OF THERMAL CHOICE ON DISEASE SUSCEPTIBILITY IN FISH
UNCOVERING THE ROLE OF MICRORNAS BY DEEP SEQUENCING DURING THE ONTOGENETIC DEVELOPMENT OF THE SALMON LOUSE CALIGUS ROGERCRESSEYI
Mining microarrays for development of innovative tools for fish health in aquaculture
Interdisciplinary Center for Aquaculture Research (INCAR)
An integrated approach to understand the effects of enteral immunostimulation upon mucosal and systemic immunity and disease resistance across cultured finfish specie
Improvement of Aquaculture production by the use of biotechnological tools. (Mejora de la producción en acuicultura mediante herramientas de biotecnología) (Aquagenomics)
Regulation of Head-Kidney cells in fish
Understanding of the basic mechanisms involved in coping strategies of fish towards improvement of welfare
Immune-depression and stress in seabream (Saparus aurata)
Improving Immunity in aquaculture animals (IMAQUANIM)
Distribution and dispersal of benthic macrofauna with direct development=> the link between benthic and pelagic peracarid assemblages from macroalgae
50
Sebastian Boltana

Profesor Asociado

Occeanografia

Universidad de Concepcion

Concpecion, Chile

10
Cristian Gallardo

Profesor Asociado

Departamento de Oceanografía

Universidad de Concepción

Concepcion, Chile

4
Martin Thiel

Profesor Titular

Biologia Marina

Universidad Católica del Norte

Coquimbo, Chile

4
Juan Valdés

Head lab

Ciencias Biologicas

UNIVERSIDAD ANDRÉS BELLO

Santiago, Chile

3
Jorge Aedo

Asistente de Investigación

Ciencias Biológicas

Universidad Andrés Bello

Santiago, Chile

3
Luis Mercado

Profesor Titular

Instituto de Biología

Pontificia Universidad Católica de Valparaíso

Valparaíso, Chile

3
Nelson Valdivia

Associate Professor

Universidad Austral de Chile

Valdivia, Chile

3
Gustavo Núñez

Investigador Postdoctoral

Vicerrectoría de Investigación y Desarrollo

Universidad de Concepción

Concepción, Chile

2
Gabriel Arriagada

Profesor Asistente

Instituto de Ciencias Agroalimentarias, Animales y Ambientales (ICA3)

Universidad de O'Higgins

San Fernando, Chile

2
Claudio Meneses

Profesor Titular

Facultad de Ciencias de la Vida

UNIVERSIDAD ANDRÉS BELLO

Santiago, Chile

2
Nelson Valdivia

Assistant Professor

Instituto de Ciencias Marinas y Limnologicas

INSTITUTO DE CIENCIAS MARINAS Y LIMNOLÓGICAS (ICML), UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

2
Andrea Donoso

Investigadora y encargada de Gestión Tecnológica

Centro de Biotecnología

Universidad de Concepción

concepcion, Chile

2
Erasmo Macaya

Profesor Asociado

Departamento de Oceanografía

UNIVERSIDAD DE CONCEPCIÓN

Concepción, Chile

1
Jose Yañez

Profesor Asistente

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Ivan Hinojosa

Profesor Asistente

Ecología

Universidad Católica de la Santisima Concepción

Concepcion, Chile

1
DORIS SOTO

Investigador Principal

Oceanografia

Universidad de Concepcion

Puerto Montt, Chile

1
JONATHAN MALDONADO

Postdoc CONICYT

Dpto. Genética Molecular y Microbiología

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Adolfo Henríquez

Colaborador Académico

Departamento de Química Analítica e Inorgánica

Universidad de Concepción

Concepción, Chile

1
David Contreras

Full professor

Analitycal and Inorganic Chemistry

UNIVERSIDAD DE CONCEPCION

Concepción, Chile

1
Juan Manuel Vega

Investigador Asociado

Biología Marina

Universidad Católica del Norte

Coquimbo, Chile

1
Ana Goncalves

Investigador

Centro de Biotecnologia

Universidad de Concepción

ConcepciónConcepción, Chile

1
Estefanía Tarifeño

Assistant professor

Bioquímica y Biología Molecular

Universidad de Concepción

Concepción, Chile

1
Valentina Valenzuela

Investigador adjunto

Universidad de Concepcion

Concepción, Chile

1
Cristián Correa

Profesor Adjunto

Facultad de Ciencias Forestales y Recursos Naturales

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

1
Rodolfo Farlora

Full time professor

Instituto de Biología

Universidad de Valparaíso

Valparaiso, Chile

1
Patricio Hernáez

Investigador colaborador

Instituto de Biociências

Universidade Estadual de São Paulo Julio de Mesquita Filho

São Vicente, Brasil

1
Marcelo Rivadeneira

Senior Researcher

Centro de Estudios Avanzados en Zonas Aridas (CEAZA)

Coquimbo, Chile

1
Katherine Márquez

Researcher

Researcher

Centro de Estudios en Alimentos Procesados

Talca, Chile

1
Alejandro Buschmann

FULL PROFESSOR

UNIVERSIDAD DE LOS LAGOS

PUERTO MONTT, Chile

1
Felipe Reyes

Associate profesor - Head of UAB Fish transcriptomics platform

Universitat Autònoma de Barcelona

Barcelona, España

1
Carmen Imarai

Profesor Titular

Biología

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

1
Herman Silva

Professor

Departamento de Produccion Agricola

Universidad de Chile

Santiago, Chile