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Maria Soledad Matus Montero

Principal Investigator

Fundacion Ciencia & Vida

Santiago, Chile

Líneas de Investigación


Estudiamos la contribución de la respuesta integrada al estrés (REI) al proceso neurodegenerativo y al envejecimiento. Utilizando herramientas genéticas y farmacológicas, estudiamos las consecuencias de modular la REI en el envejecimiento y las enf

Educación

  •  Cellular and Molecular Biology, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2007
  •  Biochemist, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2001
  •  Biochemistry, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2000

Experiencia Académica

  •   Post Doctoral Full Time

    UNIVERSIDAD DE CHILE

    Medicine

    Santiago, Chile

    2008 - 2009

  •   Young Investigator Full Time

    UNIVERSIDAD DE CHILE

    Medicine

    Santiago, Chile

    2010 - 2012

  •   Principal Investigator Full Time

    FUNDACION BIOMEDICA NEUROUNION

    Santiago, Chile

    2013 - 2016

  •   Investigador Principal Full Time

    FUNDACION CIENCIA & VIDA

    Santiago, Chile

    2017 - A la fecha

  •   Profesor Part Time

    UNIVERSIDAD SAN SEBASTIAN

    Ciencia y Medicina

    Santiago, Chile

    2019 - A la fecha

Experiencia Profesional

  •   Principal Investigator Full Time

    Fundacion Biomedica Neurounion

    Santiago, Chile

    2013 - 2016

  •   Director Other

    Fundacion Biomedica Neurounion

    Santiago, Chile

    2017 - A la fecha

Formación de Capital Humano


ADVISOR OF THESES AND RESEARCH UNITS.
-Director Undergraduate Thesis of Felipe Gómez, titled “The role of the activating transcription factor 4 (ATF4) in A Beta induced sinaptotoxicity”. Universidad Andrés Bello. February 2020– April 2021, currently on course.
-Director Undergraduate Thesis of Juan Francsico Roa, titled “The role of Nutrient Sensor GCN2 in oligodendrocytes function in a mouse model of amyotrophic lateral sclerosis” Universidad Técnica Metropolitana. July 2020, currently on course.
-Director Undergraduate Thesis of Marcela Escandón, titled “The role of Nutrient Sensor GCN2 in cognitive impairment associated to aging “. Universidad Mayor. September 2018–March 2021.
-Director Undergraduate Thesis of Alvaro Brito, titled “Nutrient Sensor GCN2 in myelination and re-myelination “. Universidad Técnica Metropolitana. March 2019–June 2020, currently on course.
-Director of PhD Thesis of the student Luis Osorio at the PhD Program in Biomedical Sciences, at Universidad de Chile titled “Study of the Impact of PERK-ATF4 signaling pathway in a model of amyotrophic lateral sclerosis” March 2015-September 2019.
-Co-Director of PhD Thesis of the student Vicente Valenzuela at the PhD Program in Biomedical Sciences, at Universidad de Chile titled “Study of the Impact of overexpression of the transcription factor XBP1s in the central nervous system in a model of amyotrophic lateral sclerosis” March 2012-September 2017.
-Co-Director Magister Thesis of Leslie Ann Bargsted Elgueda, titled “Impact of ERp57 expression in a Transgenic Mouse Model of Amyotrophic Lateral Sclerosis“. Magister Program in Biological Science, Faculty of Sciences at Universidad de Chile. March 2015–September 2016.
-Co-Director Undergraduate Thesis of Leslie Ann Bargsted Elgueda, titled “Characterization of a New Transgenic Mouse Model of Amyotrophic Lateral Sclerosis: TDP43A315T“. March 2012–September 2014.

ADVISOR OF POSTDOCTORAL INVESTIGATORS.
-Sponsoring of Dr. Nicolás Martinez Alarcón in the Postdoctoral Project titled “Synapse degeneration associated to Alzheimer’s Disease is promoted by local synaptic PKR activation” funded by FONDECYT (N° 3200932) at Fundación Ciencia & Vida.
-Sponsoring of Dr. Paulina Falcon Urrutia in the Postdoctoral Project titled “Defining the differential contribution of ER stress to oligodendrocytes and motoneurons survival on a model of c9orf72 repeat expansion pathogenesis”, funded by FONDECYT (N° 3180189) at Fundación Ciencia & Vida.


Difusión y Transferencia


INVITED CONFERENCES and SEMINARIES.
-Matus S. “Nutrient Sensing And Redox Balance: GCN2 As a New Integrator In Aging” at the “Cellular and Molecular Aspects of Neurodegenerative Pathologies” at the XVI Annual Meeting of the Chilean Neuroscience Society. November, 9 al 13, 2020 Online.

-Matus S. “The Integrated Stress Response in health and in ALS” Baylor College of Medicine. April 24, 2019.

-Matus S. “The Integrated Stress Response in Neurodegeneration” XXXIV Annual Meeting of the Argentine Society for Research in Neuroscience. Cordova, Argentina. 3-5 October, 2019.

-Matus S. “The Integrated Stress Response in amyotrophic lateral sclerosis” ” XXXIV Annual Meeting of the Argentine Society for Research in Neuroscience. Cordova, Argentina. 3-5 October, 2019.

-Osorio L., Mallucci G., Hetz C. and Matus S. 2018 “Integrated Stress Response in Neurodegeneration” Chilean Society for Cell Biology XXXIII Annual Meeting. Puerto Varas, Chile. 22-26 October. 2018.

CONFERENCES and SEMINARIES.

2020
Matus S. “Nutrient Sensing And Redox Balance: GCN2 As a New Integrator In Aging” at the “Cellular and Molecular Aspects of Neurodegenerative Pathologies” at the XVI Annual Meeting of the Chilean Neuroscience Society. November, 9 al 13, Online.

2019
-Falcón P., Brito A., Escandón M. and Matus S. “GCN2-induced eIF2aphosphorylation is necessary for remyelination”. Chilean Society for Cell Biology XXXIII Annual Meeting. November 25-29, 2019, Puerto Varas –Chile. ORAL PRESENTATION
-Escandón M., Falcón P. and Matus S. “Low Protein diets activates the integrated stress response and protects against aging”. Chilean Society for Cell Biology XXXIII Annual Meeting. November 25-29, 2019, Puerto Varas –Chile. POSTER PRESENTATION
Osorio L., Jerez C., Mallucci G., Hetz C. and Matus S. “Modulation of the integrated stress response in a murine model of amyotrophic lateral sclerosis”. Chilean Society for Cell Biology XXXIII Annual Meeting. November 25-29, 2019, Puerto Varas –Chile. ORAL PRESENTATION
-Brito A., Falcón P., Escandón M., Jerez C., Marambio Y. and Matus S. “The nutrient stress sensor GCN2 is important in the central nervous system in mouse”. Chilean Society for Cell Biology XXXIII Annual Meeting. November 25-29, 2019, Puerto Varas –Chile. POSTER PRESENTATION
Brito A., Falcón P., Escandón M., Jerez C., Marambio Y. and Matus S. “GCN2 plays a protective role in a pharmacological demyelination model”. Neuroscience. 19-23 October, 2019. Chicago, IL, EEUU. POSTER PRESENTATION
Martínez N., Matus S. and Alfaro I. “Local Synaptic PKR activation is involved in amiloyd-beta oligomer induced synapse degeneration”. Neuroscience. 19-23 October, 2019. Chicago, IL, EEUU. POSTER PRESENTATION
Martínez N., Osorio L. and Matus S. “The Integrated Stress Response in Neurodegeneration” Sociedad Argentina de Neurociencias. 3-5 October, 2019. Villa Carlos Paz, Córdova, Argentina. ORAL PRESENTATION (S. Matus)
María-José Barrera, Sergio Aguilera, Patricia Carvajal, Isabel Castro, Daniela Jara, Sergio González, Claudio Molina, Soledad Matus and María-Julieta González “Decreased Autophagy In Salivary Glands Of Primary Sjögren’s Syndrome Patients Could Be Associated With An Increased Expression Of Inflammatory Markers”. European Congress of Rheumatology. 12-15/06/2019. Madrid. España. POSTER PRESENTATION

2018
-Falcón P., Brito A., Escandón M., Matus S. “GCN2 plays a protective role in Cuprizone induced demyelination” Cold Spring Harbor Asia. Novel Insights into Glial Function & Dysfunction. December 3-7, 2018. Suzhou, China. POSTER PRESENTATION
-Osorio L., Jerez C., Mallucci G., Hetz C. and Matus S. “Modulation of the integrated stress response protects against amyotrophic lateral sclerosis in a murine model of the disease” Chilean Society for Cell Biology XXXII Annual Meeting. October 22-26, 2018, Puerto Varas –Chile. POSTER PRESENTATION
-Falcón P., Brito A., and Matus S. “GCN2 plays a protective role in a pharmacological demyelination model” Chilean Society for Cell Biology XXXII Annual Meeting. October 22-26, 2018, Puerto Varas –Chile. POSTER PRESENTATION
-Osorio L., Jerez C., Mallucci G., Hetz C. and Matus S. “Integrated Stress Response in Neurodegeneration” Symposium “Integrated Stress Response in health and disease“. Chilean Society for Cell Biology XXXII Annual Meeting. October 22-26, 2018, Puerto Varas –Chile. ORAL PRESENTATION (S. Matus)
-Falcon P, Brito A. and Matus S. “Nutrient Sensor GCN2 in myelination and re-myelination”. FASEB Conference: Nutrient Sensing and Metabolic Signaling. 5/8/2018- 10/8/2018 Snowmass, Colorado. United States. POSTER PRESENTATION (S. Matus)
-María-José Barrera, Sergio Aguilera, Patricia Carvajal, Isabel Castro, Daniela Jara, Sergio González, Claudio Molina, Soledad Matus and María-Julieta González “Decreased Autophagy In Salivary Glands Of Primary Sjögren’s Syndrome Patients Could Be Associated With An Increased Expression Of Inflammatory Markers”. European Congress of Rheumatology. 12-15/06/2019. Madrid. España. POSTER PRESENTATION

2017
Bargsted L., Budini M., Muñoz N., Osorio L., Hetz C. and Matus S. “Impaired stress responses and misfolding of TDP-43 in a mouse model of FTD-ALS”. EMBO Meeting. “Impaired stress responses and misfolding of TDP-43 in a mouse model of FTD-ALS” June 14-17, 2017. Heidelbeg. Germany. POSTER PRESENTATION
Bargsted L., Budini M., Muñoz N., Osorio L., Hetz C. and Matus S. “Neurodegeneration and Impaired stress responses in a TDP-43 mouse model of FTD-ALS”. Gordon Research Conference: Amyotrophic Lateral Sclerosis (ALS) & Related Motor Neuron Diseases. July, 23-28, 2017. Stoweflake Conference Center. Stowe. Vermont. United States. POSTER PRESENTATION
Bargsted L., Osorio L., and Matus S. 2017 “Integrated Stress Response in Neurodegeneration” Chilean Neuroscience Society Meeting. Castro, Chile. 29 Sept -2 October. 2017. ORAL PRESENTATION
Bargsted L., Budini M., Muñoz N., Osorio L., Hetz C. and Matus S. “Impaired stress responses and misfolding of TDP-43 in a mouse model of FTD-ALS”. EMBO. EMBL Symposium: Mechanisms of Neurodegeneration. 14/06/17 –17/06/17. Heidelbeg. Germany. POSTER PRESENTATION

2016
Bargsted L., Muñoz N., Hetz C. and Matus S. 2015. “Protein (mis) folding in ALS.” Gordon Conference “Stress Proteins in Growth, Development & Disease”. July 5-10. Tuscany Il Ciocco, Italy. (Speaker).

Matus S., Valenzuela V., Nasiff M and Hetz C. 2014 ”Disturbances of ER proteostasis in ALS”. The Milton Safenowitz Post Doctoral Fellowship Workshop (Sponsored by the Greater New York Chapter of The ALS Association), June 19-20. New York, EEUU.

Vicente Valenzuela, Melissa Nassif, Leslie Bargsted, Yerko Fuentealba Claudio Hetz and Soledad Matus. “Functional Contribution of the Transcription Factor ATF4 to the Pathogenesis of Amyotrophic Lateral Sclerosis (ALS)” Chilean Society for Cell Biology XXVIII Annual Meeting. October 23-27, 2013, Puerto Varas –Chile.

M. Calegaro, S. Matus, P. Thielen, L. Glimcher and C. Hetz C. 2008. XBP-1 deficiency protects against Amyotrophic Lateral Sclerosis due to increased autophagy. I Congress IBRO/LARC of Neurosciences for Latin America, Caribbean and Iberian Peninsula. September 1-4. Buzios, RJ, Brazil.

C. Hetz, P. Thielen, S. Matus, M. Nassif, R.H. Brown and L. Glimcher. 2008. XBP-1 deficiency in neurons protects against amyotrophic lateral sclerosis by increasing autophagy. Sporadic Neurodegeneration: Genes, Environment and Therapeutic Strategies. july 31-august 01 . Boston, USA.

Matus S. “Geroscience” at “Envejecer, un desafió y una oportunidad”. Department of Cognitive Neurology and Dementia. September 1, 2017.
Matus S. Talk at FONDAP Geroscience Center for Brain Health and Metabolism. May 25th 2017 Faculty of Sciences. Universidad de Chile.

PARTICIPATION AS EDITOR
- Scientific Report, Editorial Board Member (2018).
- Frontiers in Neuroscience, Guest Editor (2019).

OUTREACH ACTIVITIES

NON SCIENTIFIC (SOCIETY) ACTIVITIES.

- Speaker at “Encuentros El Mercurio”. “Ayuno Intermitente ¿Moda o Hábito Saludable?” September 30, 2020. Virtual Conference.
-Talk at “Protagonistas 2030”. 29 August 2018. Casa Piedra, Santiago, Chile. “Muévete por tu salud: ciencia, alimentación y deporte”. “Encuentros El Mercurio”.
-Talk at “Encuentros El Mercurio”. "LA REVOLUCIÓN DE LA TENDENCIA LOW CARB" 28 March 2018. Centro Cívico Vitacura.
-Talk at “Festival Puerto Ideas”. Auditorium Colegio San Luis. Antofagasta, Chile. April 8th, 2017. Aging Pannel.

PARTICIPATION IN BOARDS
-From December 2018 part of “Puerto de Ideas” Scientific Advisory Board.
-From August 2019 part of “Instituto de Neuroprotección Infantil (INPI)” Scientific Advisory Board.

2018
-Interview at "Exploradores" - Miércoles 28 de noviembre 2018. 24 horas.
-Interview at "Futuro 360", CNN Chile, capítulo 21: Prolongación de la vida 27-11-2018
-Talk at Protagonistas 2030. 29 de agosto de 2018, Casa Piedra, Santiago, Chile. “Muévete por tu salud: ciencia, alimentación y deporte”
-Talk at “Encuentros El Mercurio”. "LA REVOLUCIÓN DE LA TENDENCIA LOW CARB" 28/03/2018 Centro Cívico Vitacura

2017
Talk at “Festival Puerto Ideas”. Auditorium Colegio San Luis. Antofagasta, Chile. April 8th, 2017. Aging Pannel.
Seminar to students and Professors of the Psychology Faculty at Universidad Santo Tomás, Antofagasta. April 7th, 2017.
Talk at FONDAP Geroscience Center for Brain Health and Metabolism. May 25th 2017 Faculty of Sciences. Universidad de Chile.
TV Interview at news Program TVN, about Aging and Science.
Participation as host of the TV Program “Patria Científica” by VTR CHILE, May Edition.
Radio Interview in “Radio Oasis”. “Intensamente” Program. May 15th 2017.
Radio Interview in “Radio La Clave”. “Pensar es Clave” Program. April 4th 2017.
Radio Interview in “Radio Bio-Bio Norte”. “MaderoFM” Program. April 20th 2017.
Interview at YA magazine “El Mercurio”. April 4th 2017.
Interview at Paula.cl “To age with another eyes” March 27th 2017.
2016
TV Interview: TV Interview at news Program TVN, about our research in ALS field and open to the community our progression and contribution in this pathology. March 27th 2016.
2105
News Paper Interview, “La Tercera” about the research in ALS we develop at the laboratory. November 2015.



 

Article (23)

Enforced dimerization between XBP1s and ATF6f enhances the protective effects of the UPR in models of neurodegeneration
Tofacitinib counteracts IL-6 overexpression induced by deficient autophagy: implications in Sjögren’s syndrome
Dopamine receptor D3 signalling in astrocytes promotes neuroinflammation
Network approach identifies Pacer as an autophagy protein involved in ALS pathogenesis.
Nutrient Sensing and Redox Balance: GCN2 as a New Integrator in Aging
Genome-wide circulating microRNA expression profiling reveals potential biomarkers for amyotrophic lateral sclerosis
Disulfide cross-linked multimers of TDP-43 and spinal motoneuron loss in a TDP-43(A315T) ALS/FTD mouse model
ALS-linked protein disulfide isomerase variants cause motor dysfunction
ER chaperones in neurodegenerative disease: Folding and beyond
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
The Protein-disulfide Isomerase ERp57 Regulates the Steady-state Levels of the Prion Protein
A new method to measure autophagy flux in the nervous system
Autophagy meets fused in sarcoma-positive stress granules
Pathogenic role of BECN1/Beclin 1 in the development of amyotrophic lateral sclerosis
Functional Contribution of the Transcription Factor ATF4 to the Pathogenesis of Amyotrophic Lateral Sclerosis
Measurement of autophagy flux in the nervous system in vivo
Trehalose delays the progression of amyotrophic lateral sclerosis by enhancing autophagy in motoneurons
Perk-dependent repression of miR-106b-25 cluster is required for ER stress-induced apoptosis
Protein folding stress in neurodegenerative diseases: a glimpse into the ER
Amyotrophic Lateral Sclerosis Pathogenesis: A Journey Through the Secretory Pathway
XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy
XBP-1 deficiency in the nervous system reveals a homeostatic switch to activate autophagy
Antiribosomal-P autoantibodies from psychiatric lupus target a novel neuronal surface protein causing calcium influx and apoptosis

Abstract (3)

Are unfolded protein response pathways modulated by inflammation in salivary glands of Sjogrens syndrome patients?
Autoantibodies against ribosomal P proteins recognize a novel surface protein in brain neurons
Blocking autoantibodies against the dopamine transporter in a SLE patient with psychosis

BookWhole (2)

Dual role of autophagy in neurodegenerative diseases: The case of amyotrophic lateral sclerosis
Targeting endoplasmic reticulum stress pathways to treat neurological disorders associated with protein misfolding

ConferencePoster (5)

Impaired stress responses and misfolding of TDP-43 in a mouse model of ALS/FTD.
Impaired stress responses and misfolding of TDP-43 in a mouse model of FTD-ALS.
Misfolding of TDP43 and Impaired Stress Responses in a Mouse Model of FTD-ALS.
"Protein Mis Folding in ALS"
Disturbances in ER Proteostasis in ALS

EditorialMaterial (2)

Common Ground: Stem Cell Approaches Find Shared Pathways Underlying ALS
Hormesis Protecting neurons against cellular stress in Parkinson disease

Note (1)

ERp57 in neurodegeneration and regeneration

Proyecto (10)

REVEALING THE ROLE OF THE PERK-ATF4 PATHWAY IN AMYOTROPHIC LATERAL SCLEROSIS AND ITS THERAPEUTIC POTENTIAL.
CONTROL OF DOPAMINERGIC NEURONAL SURVIVAL BY INSULIN GROWTH FACTOR 2 (IGF-2)=> A POSSIBLE ROLE IN PARKINSON´S DISEASE.
Neuronal network-based initiative (NBI): Understanding the causes of neuronal vulnerability in disease
“Gene therapy strategy to target the Unfolded Protein Response (UPR) in ALS”
UPRplus a new gene therapy for Parkinson`s disease treatment.
DEFINING THE CONTRIBUTION OF THE PROTEIN DISULFIDE ISOMERASE ERP57 TO ALS.
DEFINING THE CONTRIBUTION OF THE PROTEIN DISULFIDE ISOMERASE ERP57 TO ALS.
"Identification of the Role of the Unfolded Protein Response Signaling Pathway in the Development of Amyotrophic Lateral Sclerosis".
THE ROLE OF THE UNFOLDED PROTEIN RESPONSE ON NEURODEGENERATION IN AMYOTROPHIC LATERAL SCLEROSIS
THE ROLE OF THE UNFOLDED PROTEIN RESPONSE ON NEURODEGENERATION IN AMYOTROPHIC LATERAL SCLEROSIS.

Review (3)

Targeting autophagy in neurodegenerative diseases
ER dysfunction and protein folding stress in ALS
The stress rheostat: An interplay between the unfolded protein response (UPR) and autophagy in neurodegeneration
43
Maria Matus

Principal Investigator

Fundacion Ciencia & Vida

Santiago, Chile

9
Melissa Calegaro

Investigadora Principal

Centro de Biología Integrativa

Universidad Mayor

Santiago, Chile

5
Felipe Court

Full Professor and Director

Center for Integrative Biology

Universidad Mayor

Huechuraba, Chile

5
Karen Castillo

Investigadora

Laboratorio de Sensores Moleculares, Centro Interdisciplinario de Neurociencia de Valparaíso (CINV), Facultad de Ciencias, Universidad de Valparaíso

Valparaiso, Chile

3
René Vidal

Profesor Asistente

Universidad Mayor

Santiago, Chile

3
Pablo Rozas

Asistente de Investigación

Instituto de Neurociencia Biomédica

Universidad de Chile

Santiago, Chile

3
Luis González

Full Professor

School of Medicine

Universidad San Sebastián

Santiago, Chile

2
Ute Wohlbier

Associate Professor

Center for Integrative Biology

Universidad Mayor de Chile

Santiago, Chile

2
Brigitte van Zundert

Full Professor

UNIVERSIDAD ANDRÉS BELLO, CENTRO DE INVESTIGACIONES BIOMÉDICAS

Santiago, Chile

2
Jose Matamala

Assistant Professor of Neurology

Department of Neurological Science

University of Chile

Santiago, Chile

2
Danilo Bilches

Staff Scientist

Instituto de Neurociencia Biomedica

Santiago, Chile

2
Catherine Andreu

Estudiante de Doctorado

Escuela de Psicología

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Vinicius Maracaja

Profesor Asistente

Advanced Center for Chronic Diseases - ACCDiS

Univesidad de Chile

Santiago, Chile

1
Fernando Bustos

Profesor Asistente

Facultad de Medicina

Universidad Andres Bello

Santiago, Chile

1
Diego Rojas

Assistant Professor

Center for Integrative Biology

Universidad Mayor

Santiago, Chile

1
Carolina Sanchez

Assistant Professor, Faculty of Science; Principal Investigator of Advanced Genomics Laboratory; Head of DNA Sequencing Core of the Center for Genomics and Bioinformatics

Center for Genomics and Bioinformatics

Universidad Mayor

Santiago, Chile

1
Jorge Ojeda

Académico investigador

Ciencias Básicas y Morfología

Universidad Católica de la Santisima Concepción

Concepción, Chile

1
Karina Palma

Postdoctorado

Instituto de Neurociencia Biomédica BNI

Universidad de Chile

Santiago, Chile

1
Valentina Valenzuela

Investigador adjunto

Universidad de Concepcion

Concepción, Chile

1
Alfredo Sagredo

Investigador Postdoctoral

ICBM

Universidad de Chile

Santiago, Chile

1
Maria Lisbona

Postdoctorado

Biología

Universidad de Chile

Santiago, Chile

1
Viviana Pérez

Investigador Postdoctoral

Facultad de Medicina

Universidad Andrés Bello

Santiago, Chile

1
Luis Barros

Principal Research

Laboratorio Biología Molecular

CENTRO DE ESTUDIOS CIENTÍFICOS

Valdivia, Chile

1
Claudio Hetz

Deputy Director

INSTITUTO DE CIENCIAS BIOMÉDICAS, FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

SANTIAGO, Chile

1
JUAN PABLO HENRIQUEZ

Associate Professor

Cell Biology

UNIVERSIDAD DE CONCEPCIÓN, FACULTAD DE CIENCIAS BIOLÓGICAS, DEPARTAMENTO DE BIOLOGÍA CELULAR

Concepción, Chile

1
Pablo Henny

Profesor Asociado

Anatomía Normal

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Ricardo Armisen

Associate Professor

Centro de Genética y Genómica

Universidad del Desarrollo

Santiago, Chile

1
Alicia Colombo

Profesor Asistente/Director Científico Biobanco de Tejidos y Fluidos de la Universidad de Chile

Departamento de Anatomía Patológica

Universidad de Chile

Santiago, Chile

1
Maria Bono

Profesor titular

Biologia

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Patricia Burgos

Associate Professor Programa de Doctorado en Biología Celular y Biomedicina CEBICEM

UNIVERSIDAD SAN SEBASTIÁN

Santiago, Chile

1
Ivan Alfaro

Associate Professor, Director of Innovation and Technology Development

Faculty of Medicine

Universidad del Desarrollo

Santiago, Chile

1
Rodrigo Pacheco

Associate Investigator; Head of the Laboratory of Neuroimmunology

Fundación Ciencia para la Vida

Santiago, Chile

1
Gonzalo Encina

Investigador

Family Gen

Santiago, Chile

1
Omar Porras

Assistant professor

Lab. Biología Celular

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Maria Massardo

Docente Investigador

Medicina

Universidad San Sebastián

Santiago, Chile