Man

Jose Manuel Matamala Capponi

Assistant Professor of Neurology

University of Chile

Santiago, Chile

Líneas de Investigación


Motor neurone disease - ALS Clinical Neurophysiology Transcraneal Magnetic Stimulation (TMS) Nerve Excitability Biomarkes in neurological diseases

Educación

  •  Medical Doctor (MD), UNIVERSIDAD DE CHILE. Chile, 2009
  •  Neurologist , UNIVERSIDAD DE CHILE. Chile, 2015
  •  PhD Medical Science, UNIVERSIDAD DE CHILE. Chile, 2015
  •  Master in Clinical Neurophysiology, UNIVERSIDAD DE BARCELONA. España, 2015

Experiencia Académica

  •   Assistant Professor Part Time

    UNIVERSIDAD DE CHILE

    Faculty of Medicine

    Santiago, Chile

    2015 - A la fecha

  •   Staff Neurologist and Clinical Neurophysiologist Other

    CLINICA ALEMANA

    Santiago, Chile

    2015 - A la fecha

Experiencia Profesional

  •   Postdoctoral fellow in Clinical Neurophysiology and Motor Neurone Disease Full Time

    University of Sydney

    Sydey, Australia

    2016 - 2017

  •   Training in Intraoperative Neurophysiological Monitoring (IOM) Other

    Massachusett General Hospital / Harvard University

    Boston, Estados Unidos

    2017 - 2018

Formación de Capital Humano


Training of medical students and residents of Neurology, Department of Neurological Science, Faculty of Medicine, University of Chile. Hospital del Salvador.

Co-tutor PhD in Medical Science: Rodrigo Fernandez (MD).


Premios y Distinciones

  •   Fellowship of Medical Science PhD and clinical neurology program, University of Chile

    UNIVERSIDAD DE CHILE

    Chile, 2009

    Fellowship of Medical science PhD and clinical neurology program, University of Chile.


 

Article (58)

Evaluation of autonomic function: Standards needed are now available
Motor cortical excitability predicts cognitive phenotypes in amyotrophic lateral sclerosis
A proposal for new diagnostic criteria for ALS
Cortical inexcitability defines an adverse clinical profile in amyotrophic lateral sclerosis
Early focality and spread of cortical dysfunction in amyotrophic lateral sclerosis: A regional study across the motor cortices
Epidemiology of chronic inflammatory demyelinating polyneuropathy in the South-Eastern area of Santiago, Chile
Interrogating interneurone function using threshold tracking of the H reflex in healthy subjects and patients with motor neurone disease
NOTCH3 Gene Mutation in a Chilean Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy Family
Amyotrophic lateral sclerosis diagnostic index Toward a personalized diagnosis of ALS
Network approach identifies Pacer as an autophagy protein involved in ALS pathogenesis
Relationship between infarct size and serum uric acid levels during the acute phase of stroke
The effect of coil type and limb dominance in the assessment of lower-limb motor cortex excitability using TMS
[Neuropathy and Fabry's disease. Report of five cases].
[O6-methylguanine-DNA-methyltransferase (MGMT) expression in patients with glioblastoma multiforme].
A unified model of the excitability of mouse sensory and motor axons
Comparison of cross-sectional areas and distal-proximal nerve ratios in amyotrophic lateral sclerosis
Ectopic impulse generation in peripheral nerve hyperexcitability syndromes and amyotrophic lateral sclerosis
Excitability of sensory axons in amyotrophic lateral sclerosis
Expresión de O6-metilguanina-ADN-metiltransferasa (MGMT) en pacientes chilenos con glioblastoma multiforme
Genome-wide circulating microRNA expression profiling reveals potential biomarkers for amyotrophic lateral sclerosis
Genome-wide circulating microRNA expression profiling reveals potential biomarkers for amyotrophic lateral sclerosis.
In vivo evidence for reduced ion channel expression in motor axons of patients with amyotrophic lateral sclerosis
Inter-session reliability of short-interval intracortical inhibition measured by threshold tracking TMS
Inter-session reliability of short-interval intracortical inhibition measured by threshold tracking TMS.
Primary lateral sclerosis and the amyotrophic lateral sclerosis-frontotemporal dementia spectrum
[Acute polyradiculoneuropathy associated with human Herpes Virus 7 in an immunocompetent patient. Case report].
Cortical function and corticomotoneuronal adaptation in monomelic amyotrophy
Detection of fasciculations in amyotrophic lateral sclerosis: The optimal ultrasound scan time
Differentiating lower motor neuron syndromes
Dynamic muscle ultrasound identifies upper motor neuron involvement in amyotrophic lateral sclerosis
Landmark Papers in Neurology
Laterality of motor cortical function measured by transcranial magnetic stimulation threshold tracking
Natural history and the dawning of a new era for familial ALS
Natural history and the dawning of a new era for familial ALS.
Prognostic factors in C9orf72 amyotrophic lateral sclerosis
Quantitative muscle ultrasound as a biomarker in Charcot-Marie-Tooth neuropathy
[Pontine reversible leucopathy in an AIDS patient associated with highly active antiretroviral therapy (HAART)=> Report of one case].
Treatment approaches in motor neurone disease
Vitamin B-12 treatment of asymptomatic, deficient, elderly Chileans improves conductivity in myelinated peripheral nerves, but high serum folate impairs vitamin B-12 status response assessed by the combined indicator of vitamin B-12 status
ER stress signaling and neurodegeneration: At the intersection between Alzheimer's disease and Prion-related disorders
The Protein-disulfide Isomerase ERp57 Regulates the Steady-state Levels of the Prion Protein
The Protein-disulfide Isomerase ERp57 Regulates the Steady-state Levels of the Prion Protein.
[Overlapping features of frontotemporal dementia and amyotrophic lateral sclerosis].
Novel therapeutic strategies for traumatic brain injury: acute antioxidant reinforcement
Vitamin B12 status does not influence central motor conduction time in asymptomatic elderly people: A transcranial magnetic stimulation study
[Bifrontal cerebritis and brain abscess caused by Sreptococcus anginosus group=> report of one case].
Bifrontal cerebritis and brain abscess caused by Sreptococcus anginosus group. Report of one case
Delayed recurrent stroke in a young patient with acute posterior multifocal placoid pigment epitheliopathy
Motor evoked potentials by transcranial magnetic stimulation in healthy elderly people
Oxidative stress and pathophysiology of ischemic stroke: Novel therapeutic opportunities
Oxidative stress and pathophysiology of ischemic stroke=> novel therapeutic opportunities.
Vitamin B12 status does not influence central motor conduction time in asymptomatic elderly people: A transcranial magnetic stimulation study.
Altered Prion Protein Expression Pattern in CSF as a Biomarker for Creutzfeldt-Jakob Disease
Central pontine myelinolysis after liver transplantation. Report of five cases
Central pontine myelinolysis after liver transplantation: Report of five cases.
Neuro-otological findings in tinnitus patients with normal hearing
Association of GST M1 null polymorphism with Parkinson's disease in a Chilean population with a strong Amerindian genetic component
Manifestaciones neuropsiquiátricas y cognitivas en demencia frontotemporal y esclerosis lateral amiotrófica: dos polos de una entidad común

Abstract (2)

Bci is a new component of the autophagy pathway
Correlation of lactate dehydrogenase activity and 14-3-3 protein in cerebrospinal fluid from patients with Creutzfeldt-Jakob disease

CaseReport (3)

Compromiso neuropático y autonómico en Enfermedad de Fabry: presentación de casos clínicos
Polirradiculoneuritis aguda asociada a infección por Virus Herpes Humano 7 en un paciente adulto inmunocompetente
Leucopatía reversible de la protuberancia: en paciente con SIDA y tratamiento retroviral

Editorial (2)

Clinical neurophysiology standards of EMG instrumentation: Twenty years of changes
Single fiber EMG guidelines: Moving towards a "single" methodological consensus

Letter (3)

Cerebral ring enhancing lesion with diffusion restriction in a South American patient
O-6-methylguanine-DNA-methyltransferase immunostaining intensity in glioblastoma
Prevalence of body dysmorphic disorder in Chilean dermatological patients

Proyecto (8)

Instituto Milenio de Neurociencia Biomédica (BNI)
SOCIAL COGNITION IN THE AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEMENTIA CONTINUUM
Polimorfismos de HLA-A y HLA-B como factores de riesgo genético a reacciones cutáneas de hipersensibilidad a carbamazepina.
Diagnostic criteria for neuropathic pain of central and peripheral origen, A prospective clinical, electrophysiological and inmunopathological study.
Neuronal network initiative=> Understanding selective neuronal vulnerability in neurodegenerative diseases.
Perfil de expresion de microRNAs circulantes como biomarcador de esclerosis lateral amiotrofica (ELA).
Potenciales evocados motores mediante estimulación magnética transcraneal en sujetos con déficit subclinico de vitamina B12.
Impacto Funcional de la Deficiencia Subclínica de Vitamina B12 sobre las Esferas Cognitiva y de Neuroconducción en adultos mayores. Evaluación Controlada de un Programa de Suplementación.

Review (2)

Idiopathic inflammatory myopathies. A review
Overlapping features of frontotemporal dementia and amyotrophic lateral sclerosis
59
Jose Matamala

Assistant Professor of Neurology

Department of Neurological Science

University of Chile

Santiago, Chile

4
Ute Wohlbier

Associate Professor

Center for Integrative Biology

Universidad Mayor de Chile

Santiago, Chile

3
Hugo Sanchez

Asesor

Subdirección Medica

Servicio de Salud Metropolitano sur

SANTIAGO, Chile

3
Cecilia Albala

Director, full professor

INTA/U CHILE

Santiago, Chile

3
Rodrigo Fernández

Instructor Adjunto

Ciencias Neurológicas Oriente

Universidad de Chile

Santiago, Chile

2
Lydia Lera

Profesor Titular

INTA University of Chile

Santiago de Chile, Chile

2
Maria Matus

Principal Investigator

Fundacion Ciencia & Vida

Santiago, Chile

2
Melissa Calegaro

Investigadora Principal

Centro de Biología Integrativa

Universidad Mayor

Santiago, Chile

1
Carolina Sanchez

Assistant Professor, Faculty of Science; Principal Investigator of Advanced Genomics Laboratory; Head of DNA Sequencing Core of the Center for Genomics and Bioinformatics

Center for Genomics and Bioinformatics

Universidad Mayor

Santiago, Chile

1
Patricio Manque

VICE PRESIDENT FOR RESEARCH AND FULL PROFESSOR

UNIVERSIDAD MAYOR

Santiago, Chile

1
Vinicius Maracaja

Profesor Asistente

Advanced Center for Chronic Diseases - ACCDiS

Univesidad de Chile

Santiago, Chile

1
Ramón Rodrigo

PROFESOR TITULAR

INSTITUTO DE CIENCIAS BIOMÉDICAS

UNIVERSIDAD DE CHILE, FACULTAD DE MEDICINA, INSTITUTO DE CIENCIAS BIOMÉDICAS, PROGRAMA DE FARMACOLOGÍA MOLECULAR Y CLÍNICA

Santiago, Chile

1
Diego Rojas

Assistant Professor

Center for Integrative Biology

Universidad Mayor

Santiago, Chile

1
Camilo Sotomayor

Residente

Radiología

Hospital Clínico Universidad de Chile

Santiago, Chile

1
Beatriz Fonseca

ASESORA I+D

GENOMA MAYOR

Santiago, Chile

1
Agustin Ibañez

DIRECTOR

INCYT

CABA, Argentina

1
Catherine Andreu

Estudiante de Doctorado

Escuela de Psicología

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Claudio Hetz

Deputy Director

INSTITUTO DE CIENCIAS BIOMÉDICAS, FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

SANTIAGO, Chile

1
Marcelo Miranda

Neurólogo

Neurología

CLINICA LAS CONDES

Santiago, Chile

1
Andrea Slachevsky

Associate Professor

ICBM

UNIVERSIDAD DE CHILE

Chile, Chile

1
Agustin Ibanez

Profesor Titular

Psicologia

Universidad Adolfo Ibánez

Santiago, Chile

1
Patricia Lillo

Assistant professor

Neurología sur

Departamento de Neurología Sur. Facultad de Medicina. Universidad de Chile

Santiago, Chile

1
Renato Verdugo

Professor

Medicine

Clinica Alemana-Universidad del Desarrollo

Santiago, Chile

1
Pablo Rozas

Asistente de Investigación

Instituto de Neurociencia Biomédica

Universidad de Chile

Santiago, Chile

1
Danilo Bilches

Staff Scientist

Instituto de Neurociencia Biomedica

Santiago, Chile

1
RODRIGO CARRASCO

CLINICAL FELLOW

CARDIOLOGIA

UNIVERSITY OF TORONTO

Toronto, Canada

1
Luisa Herrera

Profesor Asociado

Incstituto de Ciencias Biomédicas, Programa de Genética Humana

UNIVERSIDAD DE CHILE, FACULTAD DE MEDICINA-ICBM

Santiago, Chile