Man

JUAN PABLO RODRIGUEZ VIVES

FULL PROFESSOR

INTA, UNIVERSIDAD DE CHILE

SANTIAGO, Chile

Líneas de Investigación


The research interest of our laboratory has been focused on determining the role played by mesenchymal stem cells (MSCs) in the pathogenesis of postmenopausal osteoporosis.

Educación

  •  CIENCIAS, BIOLOGIA, UNIVERSIDAD DE CHILE. Chile, 1991

Experiencia Académica

  •   FULL PROFESSOR Full Time

    UNIVERSIDAD DE CHILE

    INTA

    Santiago, Chile

    1981 - A la fecha

  •   Full Profesor Full Time

    UNIVERSIDAD DE CHILE

    INTA

    Santiago, Chile

    1981 - A la fecha

Experiencia Profesional

  •   FULL PROFESSOR Full Time

    INTA, UNIVERSIDAD DE CHILE

    SANTIAGO, Chile

    1981 - A la fecha

Formación de Capital Humano


Tutor of Postgraduate students (Thesis):
Carolina Figueroa A. Magister en Nutrición y Alimentos, m / Alimentos Saludables. INTA. U. de Chile
Melissa Miranda. Doctorado en Nutrición y Alimentos. Programa Interfacultades. U de Chile
Constanza Martínez. Doctorado en Ciencias, Mención Biología Celular, Molecular y Neurociencias. Fac. de Ciencias. U. de Chile
Pablo Astudillo. Magíster en Ciencias Biológicas. Facultad de Ciencias. U de Chile

Tutor of Undergraduate students (Thesis)
Consuelo Balanda. Odontología, Facultad de Odontología, Universidad de Chile
Celeste Avalos. Ingeniería en Biotecnología Molecular, Facultad de Ciencias. Universidad de Chile
César Navea. Bioquímica, USACH
Oscar Donoso. Bioquímica, Universidad Católica de Valparaíso
Andrea Flores. Ingeniería en Biotecnología Molecular, Facultad de Ciencias. Universidad de Chile.
Pablo Astudillo. Ingeniería en Biotecnología Molecular, Facultad de Ciencias.



 

Article (31)

Real-Time H2O2 Measurements in Bone Marrow Mesenchymal Stem Cells (MSCs) Show Increased Antioxidant Capacity in Cells From Osteoporotic Women
Unsaturation Level Decreased in Bone Marrow Fat of Postmenopausal Women with Low Bone Density Using High Resolution Magic Angle Spinning (HRMAS) 1H-NMR Spectroscopy
Characterization of fatty acid composition in bone marrow fluid from postmenopausal women: Modification after hip fracture
Osseointegration properties of titanium dental implants modified with a nanostructured coating based on ordered porous silica and bioactive glass nanoparticles.
Qualitative Aspects of Bone Marrow Adiposity in Osteoporosis
Osteoporosis-associated alteration in the signalling status of BMP-2 in human MSCs under adipogenic conditions.
The Effect of the Nanoscale Structure of Nanobioceramics on their In Vitro Bioactivity and Cell Differentiation Properties.
Synthesis of nanostructured porous silica coatings on titanium and their cell-adhesive and osteogenic differentiation properties
In Osteoporosis, differentiation of mesenchymal stem cells (MSCs) improves bone marrow adipogenesis
Matrix IGF-1 maintains bone mass by activation of mTOR in mesenchymal stem cells
RELACION ENTRE GRASA Y EL HUESO: MECANISMO CLAVE EN LA OSTEOPOROSIS
Sonic Hedgehog stimulates Proliferation of Human Periodontal Stem Cells
Concentration of adipogenic and pro inflammatory cytokines in the bone marrow supernatant fluid of osteoporotic women
Multiple myeloma bone marrow stromal cells characterize by increased expression of receptor activator of nuclear -B ligand (RANKL) which is inhibited by the bisphosphonate ibandronate
Adipogenesis and osteoporosis Adipogénesis y osteoporosis
Marrow Fat and the Bone Micro-Environment: Developmental, Functional and Pathological Implications
Increased adipogénesis of osteoporotic human-msenchymal stem cells (MSCs) characterizes by impaired leptin action
Aromatase activity of human mesenchymal stem cells is stimulated by early differentiation, vitamin D and leptin
High affinity leptin receptors are present in human mesenchymal stem cells (MSCs) derived from control and osteoporotic donors
CYTOSKELETAL ORGANIZATION OF HUMAN MESENCHYMAL STEM CELLS (MSC) CHANGES DURING THEIR OSTEOGENIC DIFFERENTIATION
DIFFERENTIAL ACTIVATION OF ERK1,2 MAP KINASE SIGNALING PATHWAY IN MESENCHYMAL STEM CELL FROM CONTROL AND OSTEOPOROTIC POSTMENOPAUSAL WOMEN
Modulation of the proliferation and differentiation of human stem cell s by copper
Effects of zinc on cell proliferation and proteoglycan characteristics of epiphyseal chondrocytes
Sodium fluoride induce changes on proteoglycans synthesized by avian osteoblasts in culture
Mesenchymal stem cells from osteoporotic patients produce a type I collagen-deficient extracellular matrix favoring the adipogenic differentiation
Abnormal osteogenesis in osteoporotic patients is reflected by altered Mesenchymal Stem Cells dynamics.
SOLUBLE FACTORS SECRETED BY PC-3 CELLS INDUCE STRUCTURAL CHANGES IN PROTEOGLYCANS PRODUCED BY FETAL RAT OSTEOBLASTS
Dermatan sulfate proteoglycans from the mineralized matrix of the avian eggshell
Cellular basis of bone tissue development Bases celulares del desarrollo del tejido óseo
Molecular aspects of osteogenic phenomena Aspectos moleculares del fenómeno osteogénico
The avian eggshell extracellular matrix as a model for biomineralization

BookSection (1)

Mesenchymal Stem Cells (MSC) in Osteoporotic Patients

Proyecto (4)

Functional alterations in IGF-1, BMP-2 and Wnt signaling are distinctive of mesenchymal stem cells (MSCs) from the bone marrow of osteoporotic women
En la osteoporosis, los adipocitos de la médula ósea generan un microambiente que favorece la vía de diferenciación adipogénica.
Rol protector de la leptina en la osteoporosis: Efecto sobre las células progenitoras mesenquimáticas humanas (MSCs).
Disrupted relationship between the metabolic status and the differentiation potential in human osteoporotic mesenchymal stem cells (MSCs).

Review (3)

ADIPOGENESIS AND OSTEOPOROSIS
Adipogénesis y osteoporosis
Involvement of Adipogenic Potential of Human Bone Marrow Mesenchymal Stem Cells (MSCs) in Osteoporosis
39
JUAN RODRIGUEZ

FULL PROFESSOR

LABORATORY OF CELL BIOLOGY

INTA, UNIVERSIDAD DE CHILE

SANTIAGO, Chile

6
Ana Pino

Associated Professor

LABORATORY OF CELL BIOLOGY

UNIVERSIDAD DE CHILE, INSTITUTO DE NUTRICIÓN Y TECNOLOGÍA DE LOS ALIMENTOS (INTA)

Santiago, Chile

2
Jorge Martinez

Profesor Titular

Laboratorio de Biología Celular

INSTITUTO DE NUTRICIÓN Y TECNOLOGÍA DE ALIMENTOS (INTA), UNIVERSIDAD DE CHILE

Santiago, Chile

1
Omar Porras

Assistant professor

Lab. Biología Celular

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Jose Arias

Full Professor

Animal Biology

FACULTAD DE CIENCIAS VETERINARIAS, UNIVERSIDAD DE CHILE

Santiago, Chile

1
Karen Fuenzalida

Encargado de confirmación diagnóstica de Errores Innatos del Metabolismo (EIM) mediante técnicas GCMS y LCMSMS

Instituto de Nutrición y Tecnología de Alimentos

Universidad de Chile

Santiago, Chile