PDI - Resultado de Búsqueda

Francisco Javier Sáez Orellana

Investigador asistente

Universidad de Concepción

Concepción, Chile

Neuroscience, Metabolic control, PPAR, Fatty acid metabolism, Alzheimer's disease, neurodegeneration

Cellular and Molecular Biology, UNIVERSIDAD DE CONCEPCION. Chile, 2015
Biochemistry, Universidad de Concepción. Chile, 2010

Postdoctoral Researcher Full Time

UNIVERSITE CATHOLIQUE DE LOUVAIN

Institute of Neuroscience

Brussels, Bélgica

2018 - 2020

Research assistant Part Time

Universidad de Concepción

Concepción, Chile

2021 - A la fecha
Teaching Assitant Part Time

Universidad de Concepción

Chile

2022 - A la fecha
Lecturer Part Time

Universidad San Sebastian

Concepción, Chile

2022 - 2022
Teaching assistant Part Time

Universidad de Concepción

Concepción, Chile

2015 - 2017

Becas Chile Postdoctorado en el Extranjero

CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS Y TECNOLOGICAS

Chile, 2018

Beca para la realización de postdoctorado en el extranjero
Henri Nestlé

NESTLE CHILE S.A.

Chile, 2012

Versión Científica-Nutrición, por el artículo Synaptic silencing and plasma membrane dyshomeostasis induced by amyloid-? peptide are prevented by Aristotelia chilensis enriched extract


Microglial Activation Modulated by P2X4R in Ischemia and Repercussions in Alzheimer's Disease Castillo, Carolina; Saez-Orellana, Francisco; Godoy, Pamela A.; Fuentealba, Jorge Article SCOPUS FRONTIERS IN PHYSIOLOGY (2022)
Regulation of PPAR alpha by APP in Alzheimer disease affects the pharmacological modulation of synaptic activity Saez-Orellana, Francisco; Leroy, Thomas; Ribeiro, Floriane; Kreis, Anna; Leroy, Karelle; Lalloyer, Fanny; Bauge, Eric; Staels, Bart; Duyckaerts, Charles; Brion, Jean-Pierre; Gailly, Philippe; Octave, Jean-Noel; Pierrot, Nathalie Article ISI JCI INSIGHT (2021)
Alzheimer's Disease, a Lipid Story: Involvement of Peroxisome Proliferator-Activated Receptor alpha Saez-Orellana, Francisco; Octave, Jean-Noel; Pierrot, Nathalie Article ISI CELLS (2020)
A Natural Benzofuran from the Patagonic Aleurodiscus vitellinus Fungus has Potent Neuroprotective Properties on a Cellular Model of Amyloid-beta Peptide Toxicity Mariela González-Ramírez, Javiera Gavilán; Tiare Silva-Grecchi, Daniel Cajas-Madriaga; Sergio Triviño, José Becerra; Francisco Saez-Orellana, Claudia Pérez Article Journal of Alzheimer's Disease (2018)
P2X receptor overexpression induced by soluble oligomers of amyloid beta peptide potentiates synaptic failure and neuronal dyshomeostasis in cellular models of Alzheimer's disease Francisco Saez-Orellana, Maria C. Fuentes-Fuentes; Pamela A. Godoy, Tiare Silva-Grecchi; Jessica D. Panes , Leonardo Guzmán; Gonzalo E. Yévenes, Javiera Gavilán; Terrance M. Egan, Luis G. Aguayo Article Neuropharmacology (2018)
ATP leakage induces P2XR activation and contributes to acute synaptic excitotoxiciw induced by soluble oligomers of beta-amyloid peptide in hippocampal neurons Saez-Orellana, F; Godoy PA; Bastidas, CY; Silva-Grecchi, T; Guzman, L; Aguayo, LG; Fuentealba, J Article ISI SCOPUS NEUROPHARMACOLOGY (2016)
Modulation of Neuronal Nicotinic Receptor by Quinolizidine Alkaloids Causes Neuroprotection on a Cellular Alzheimer Model Araya, Juan A; Ramírez, Alejandra E.; Figueroa-Aroca, Daniela F; Sotes, Gaston J.; Perez, Caudia; Becerra, Jose; Saez-Orellana, Francisco; Guzman, Leonardo; Aguayo, LG; Fuentealba, Jorge P Article ISI SCOPUS JOURNAL OF ALZHEIMERS DISEASE (2014)
Synaptic Silencing and Plasma Membrane Dyshomeostasis Induced by Amyloid-beta Peptide are Prevented by Aristotelia chilensis Enriched Extract Fuentealba, J; Dibarrart A; Saez-Orellana, F; Fuentes-Fuentes M C; Oyanedel, C N; Guzmán J; Pérez, C.; Becerra, J. ; Aguayo, L. G. Article ISI SCOPUS Journal of Alzheimer's Disease (2012)
Synaptic Failure and Adenosine Triphosphate Imbalance Induced by Amyloid-beta Aggregates Are Prevented by Blueberry-Enriched Polyphenols Extract Fuentealba, J; Dibarrart, AJ; Fuentes-Fuentes, MC; Saez-Orellana, F; Quinones, K; Guzman, L; Pérez, C.; Becerra, J. ; Aguayo, LG Article ISI SCOPUS Journal of Neuroscience Research (2011)


Neuroactive alkaloids that modulate the neuronal nicotinic receptor and provide neuroprotection in an Alzheimer's disease model: the case of Teline monspessulana Fuentealba, J; Saez-Orellana, F EditorialMaterial ISI SCOPUS NEURAL REGENERATION RESEARCH (2014)


Modulation of the neuronal network activity by P2X receptors and their involvement in neurological disorders Saez-Orellana, F; Godoy PA; Silva-Grecchi, T; Barra, KM; Fuentealba, J Review ISI SCOPUS Pharmacological Research (2015)

9

Francisco Sáez

Investigador asistente

Fisiología

Universidad de Concepción

Concepción, Chile

6

JORGE FUENTEALBA

Dean

Physiology

UNIVERISDAD DE CONCEPCION

Concepcion, Chile

4

JOSE GUZMAN

Full professor

Fisiología

Universidad de Concepción

Concepcion, Chile

3

Claudia Perez

Academic

Botany

University of Concepción

Concepción, Chile

3

Luis Aguayo

Full Professor

Department of Physiology

Universidad de Concepcion

Concepcion, Chile

2

JOSE BECERRA

Professor

Botany Department

UNIVERSIDAD DE CONCEPCIÓN

Concepción, Chile

2

Pamela Godoy

Colaboradora académica

Fisiología

Universidad de Concepción

Concepcion, Chile

1

Camila Bastidas

Docente

Universidad de Concepción

Concepción, Chile

1

Juan Araya

Instructor

Análisis Instrumental

Universidad de Concepción

Concepción, Chile

1

Carlos Oyanedel

Research Assistant

Institute of Medical Psychology and Behavioral Neurobiology

Eberhard Karl University of Tübingen

Tübingen, Alemania