Man

Susana Angelica Sanchez Donoso

Assistant Professor

Universidad de Concepcion

Concepcion, Chile

Líneas de Investigación


-Methods in Confocal and 2-Photon Microscopy (FCS, FLIM,GP) -Fluorescence Spectroscopy Methods (polarization, lifetimes etc) -Lipid-Protein interactions. Lipid-Lipid Interactions -Membrane Fluidity .Membrane lateral segregation and lipid domains

Educación

  •  Chemistry, PONTIFICIA UNIVERSIDAD CATOLICA DE VALPARAISO. Chile, 1997

Experiencia Académica

  •   Assistant professor Full Time

    UNIVERSIDAD DE CONCEPCION

    Ciencias Quimicas

    Concepcion, Chile

    2013 - A la fecha

  •   Staff Scientist in Biophysics Full Time

    CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CNIC

    Madrid, España

    2011 - 2013

  •   Research Scientist and LFD User Coordinator Full Time

    UNIVERSITY OF CALIFORNIA AT IRVINE

    Irvine, California, Estados Unidos

    2006 - 2011

  •   Research Physicist and LFD user Coordinator Full Time

    UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN

    Urbana, Illinois, Estados Unidos

    2000 - 2006

Formación de Capital Humano


(2013- today) QUI-530023 Introduction to Chemistry for Engineering (Universidad de Concepción)
(2013 - today) QUI 530-028 Chemistry I forNatural Resourses Engineering (Universidad de Concepción)
(2013 - today) QUI531-454 Biological Chemistry for Chemist

Co-director tesis Pregrado=2
Co-Director Tesis Postgrado=2
Miembro de Comision de Tesis de pregrado=4
Miembro de comision de Tesis de Postgrado= 1

COURSES (Graduate and undergraduate 1-2 weeks duration). Teacher and Instructor.
- Programa ACERCATE (2011 and 2012). Fundación-CNIC Carlos III (Centro Nacional de Investigaciones Cardiovasculares). Madrid. Spain.
- LFD Workshop in Advanced Fluorescence Imaging and Dynamics (LFD)(2006, 2007, 2008,2009, 2010, 2011, 2012, 2013) . Laboratory for Fluorescence Dynamics. University of California, USA.
- Fluoro 2009 workshop. School of Sciences & Technology. University of New England, Armidale, Australia.
- 2009 MCSB Bio Bootcamp Program. MCSB Graduate Program. University of California at Irvine, USA
- 2009 Introductory Course in Fluorescence Techniques, Spectroscopy and Microscopy. Center of Complex Biological Systems and LFD. U. of California at Irvine,USA.
-South-American Workshop on New trends in Advanced Fluorescence Techniques.
2007 Universidad de Buenos Aires Ciudad de Buenos Aires, Argentina. 2009. Universidad Federal de Rio de Janeiro, Rio de Janeiro, Brasil. 2011 Universidad de Buenos Aires. Ciudad de Buenos Aires, Argentina.



 

Article (62)

Correlated flickering of erythrocytes membrane observed with dual time resolved membrane fluctuation spectroscopy under different d-glucose concentrations
LAURDAN since Weber: the quest for visualizing membrane heterogeneity
CAPRYDAA, an anthracene dye analog to LAURDAN: a comparative study using cuvette and microscopy
Magnetic methacrylated gelatin-g-polyelectrolyte for methylene blue sorption
Pluronic-coated nanoparticles for enhanced spatial distribution and increased softness of nanocomposite hydrogels
Alkyl-mannoside derivatives: Glycolipids able to form big size aggregates
Curvophilic-curvophobic balance of monoalkyl-mannosides determines the magnitude of disturbance promoted in synthetic bilayers
Folding and Misfolding of Human Membrane Proteins in Health and Disease: From Single Molecules to Cellular Proteostasis
OSCILLATORY STRAIN SWEEPS OF HYDROGELS FROM METHACRYLATED ALGINATE MACROMONOMERS: ASSESSMENT OF SYNTHESIS AND ACQUISITION VARIABLES
Effect of Cholesterol on Membrane Fluidity and Association of A beta Oligomers and Subsequent Neuronal Damage: A Double-Edged Sword
Fluorescent nanotubes in PHEMA hydrogels: Visualizing aggregation and distribution by confocal fluorescence microscopy
Kinetic Study of Chiral Intermolecular Interactions by Moment Analysis Based on Affinity Capillary Electrophoresis
Photophysical characterization of hydroxy and ethoxy phenalenone derivatives
Scanning fluorescence correlation spectroscopy comes full circle
Study of rabbit erythrocytes membrane solubilization by sucrose monomyristate using laurdan and phasor analysis
Hybrid photoluminescent materials containing a benzobisthiazole core for liquid crystal and gel applications
Learning from Synthetic Models of Extracellular Matrix; Differential Binding of Wild Type and Amyloidogenic Human Apolipoprotein A-I to Hydrogels Formed from Molecules Having Charges Similar to Those Found in Natural GAGs
Rhodamine-loaded surface modified mesoporous silica particles embedded into a thermoresponsive composite hydrogel for prolonged release
Teaching Polymer Science in the Department of Polymers at the University of Concepcion, Chile: A Brief History
Understanding the interaction of concanavalin a with mannosyl glycoliposomes: A surface plasmon resonance and fluorescence study
Columnar liquid crystalline tris-(ether)triazines with pendant 1,3,4-thiadiazole groups: synthesis, mesomorphic, luminescence, solvatofluorochromic and electrochemical properties
Soft amphiphilic polyesters obtained from PEGs and silicon fatty compounds: Structural characterizations and self-assembly studies
Synthesis, Physicochemical and Photophysical Characterization of 4-(1-Pyrenyl)-butyl-alpha-D-mannopyranoside
Rac1 Nucleocytoplasmic Shuttling Drives Nuclear Shape Changes and Tumor Invasion
Structuration in the Interface of Direct and Reversed Micelles of Sucrose Esters, Studied by Fluorescent Techniques
Nonlinear optical 3-dimensional method for quantifying atherosclerosis burden
Role of plasma membrane lipid composition on cellular homeostasis: learning from cell line models expressing fatty acid desaturases
A major role for RCAN1 in atherosclerosis progression
Differential Dynamic and Structural Behavior of Lipid-Cholesterol Domains in Model Membranes
Laurdan generalized polarization fluctuations measures membrane packing micro-heterogeneity in vivo
Studies on the Dissociation and Urea-Induced Unfolding of FtsZ Support the Dimer Nucleus Polymerization Mechanism
Alpha Hemolysin Induces an Increase of Erythrocytes Calcium: A FLIM 2-Photon Phasor Analysis Approach
Factors Determining the Superior Performance of Lipid/DNA/Protammine Nanoparticles over Lipoplexes
Human Apolipoprotein A-I-Derived Amyloid: Its Association with Atherosclerosis
Major translocation of calcium upon epidermal barrier insult: imaging and quantification via FLIM/Fourier vector analysis
Methyl-beta-Cyclodextrins Preferentially Remove Cholesterol from the Liquid Disordered Phase in Giant Unilamellar Vesicles
Role of temperature-independent lipoplex-cell membrane interactions in the efficiency boost of multicomponent lipoplexes
Sucrose Monoester Micelles Size Determined by Fluorescence Correlation Spectroscopy (FCS)
Lipid packing determines protein-membrane interactions: Challenges for apolipoprotein A-I and high density lipoproteins
Membrane Organization and Regulation of Cellular Cholesterol Homeostasis
The Epidermal Ca2+ Gradient: Measurement Using the Phasor Representation of Fluorescent Lifetime Imaging
Efficient Escape from Endosomes Determines the Superior Efficiency of Multicomponent Lipoplexes
Solubilization of lipid bilayers by myristyl sucrose ester: effect of cholesterol and phospholipid head group size
Visualization and analysis of lipopolysaccharide distribution in binary phospholipid bilayers
Genetically encoded probe for fluorescence lifetime imaging of CaMKII activity
Yeast ribosomal stalk heterogeneity in vivo shown by two-photon FCS and molecular brightness analysis
Interaction of high density lipoprotein particles with membranes containing cholesterol
Visualizing association of N-Ras in lipid microdomains: Influence of domain structure and interfacial adsorption
Interaction of human apolipoprotein A-I with model membranes exhibiting lipid domains
Lipid-protein interactions revealed by two-photon microscopy and fluorescence correlation spectroscopy
Visualization and analysis of apolipoprotein A-I interaction with binary phospholipid bilayers
Tubulin equilibrium unfolding followed by time-resolved fluorescence and fluorescence correlation spectroscopy
A two-photon view of an enzyme at work: Crotalus atrox venom PLA(2) interaction with single-lipid and mixed-lipid giant unilamellar vesicles
Interaction of Apolipoprotein A-I in three different conformations with palmitoyl oleoyl phosphatidylcholine vesicles
Arrangement of apolipoprotein A-I in reconstituted high-density lipoprotein disks: An alternative model based on fluorescence resonance energy transfer experiments
Mechanisms by which intracellular calcium induces susceptibility to secretory phospholipase A(2) in human erythrocytes
Solution and interface aggregation states of Crotalus atrox venom phospholipase A(2) by two-photon excitation fluorescence correlation spectroscopy
Characterization of apolipoprotein A-I structure using a cysteine-specific fluorescence probe
Aggregation states of mitochondrial malate dehydrogenase
ELECTRON-TRANSPORT IN BIOLOGICAL PROCESSES .2. ELECTROCHEMICAL-BEHAVIOR OF Q(10) IMMERSED IN A PHOSPHOLIPIDIC MATRIX ADDED ON A PYROLITIC GRAPHITE ELECTRODE
INHIBITION OF THE OMEGA-CONOTOXIN-SENSITIVE CALCIUM CURRENT BY DISTINCT G-PROTEINS
ELECTRON-TRANSPORT IN BIOLOGICAL PROCESSES - ELECTROCHEMICAL-BEHAVIOR OF UBIQUINONE Q,10 ADSORBED ON A PYROLYTIC-GRAPHITE ELECTRODE

Abstract (6)

Photophysical Characterization and Microscopy Application of an Anthracene Analogous of Laurdan
Using Laurdan and Spectral Phasor Analysis to Study Erythrocytes Membrane Solubilization
Lactose Glicolipids and their Capabilities to form Giant Vesicles and Tubules
Membrane Heterogeneity in Erythrocytes Studied by Laurdan GP and Flim-Phasor
The nucleation of FtsZ polymerization and its 3-state unfolding are explained by the presence of mainly dimers under the critical concentration
Interaction of rHDL particles with membranes containing cholesterol in different lipid packing.

BookWhole (1)

New fluorescence microscopy approaches to explore the influence of sphingolipids on lateral organization of biomembranes: From artificial systems to cellular membranes

Proyecto (12)

MOLECULAR DETERMINANTS FOR NEUROTOXIC ACTIONS OF ABETA PEPTIDE
OPTIMIZING CHOLESTEROL REMOVAL BY HDL NANODISCS=> A TWO-PHONTON MICROSCOPY APPROACH
SUBSIDIO DE COLABORACIÓN ENTRE GRUPOS LOCALES Y EXTRANJEROS
SUPRAMOLECULAR SYSTEMS OF SUCROSE GLYCERATE DEVATIVES STUDIED BY MEANS OF FLUORESCENT TECHNIQUES
DINÁMICA DE NANOSEGUNDOS EN NA,K-ATPASA=> ROL DE DOMINIOS LIPÍDICOS SEGREGADOS EN SU FLEXIBILIDAD CONFORMACIONAL Y FUNCION.
FLUORESCENCE CHARACTERIZATION OF PLASMA MEMBRANE LATERAL HETEROGENEITY BY TWO-PHOTON EXCITATION FLUORESCENCE MICROSCOPY.
INTERACCIÓN DE PROTEÍNAS NATIVAMENTE DESPLEGADAS CON MICRO DOMINIOS DE MEMBRANA PLASMÁTICAS DE DISTINTAS CÉLULAS.
PHYSICAL CHEMICAL CHARACTERIZATION OF PURE SUCROSE MONOESTERS REVERSES MICELLES BY MEANS OF FLUORESCENT TECHNIQUES.
DINÁMICA DE NANOSEGUNDOS EN NA,K-ATPASA=> ROL DE DOMINIOS LIPÍDICOS SEGREGADOS EN SU FLEXIBILIDAD CONFORMACIONAL Y FUNCION
LABORATORY FOR FLUORESCENCE DYNAMICS
LABORATORY FOR FLUORESCENCE DYNAMICS
ESTUDIO DE LA DISOCIACION DE MALATO DESHIDROGENASA MITOCONDRIAL MEDIANTE TECNICAS FLUORESCENTES
69
Susana Sanchez

Assistant Professor

Polimeros

Universidad de Concepcion

Concepcion, Chile

12
GERMAN GUNTHER

PROFESOR Titular

Química Orgánica y Físico Química

UNIVERSIDAD DE CHILE

Santiago, Chile

5
Javier Morales

Académico - Profesor Asociado

Ciencias y Tecnología Farmacéuticas

UNIVERSIDAD DE CHILE

Santiago, Chile

4
Bruno Urbano

Profesor Asociado

Departamento de Polímeros

Universidad de Concepción

Concepción, Chile

3
Rosalba Lagos

Professor

Biología

UNIVERSIDAD DE CHILE, FACULTAD DE CIENCIAS, DEPARTAMENTO DE BIOLOGÍA

Santiago, Chile

3
Octavio Monasterio

Profesor Titular

Departamento de Biología

UNIVERSIDAD DE CHILE, FACULTAD DE CIENCIAS, DEPARTAMENTO DE BIOLOGÍA

Santiago, Chile

3
Nancy Pizarro

Associate professor

Ciencias Quimicas

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

2
Felipe Olate

Investigador Postdoctoral

Departamento de Ingeniería Química, Biotecnología y Materiales

Universidad de C

Santiago, Chile

2
Enzo Díaz

Docente

Química General

Universidad de Concepción

Concepción, Chile

1
Elizabeth Elgueta

Investigadora

Centro de Investigación de Polímeros Avanzados, CIPA

Concepción, Chile

1
Daniel Palacio

Profesor Asistente

Departamento de Polímeros

Universidad de Concepción

Concepción , Chile

1
Marco Soto

Profesor Asociado

Química Física

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Benjamin Vicente

Director de Departamento

Psiquiatría y Salud Mental

FACULTAD DE MEDICINA UNIVERSIDAD DE CONCEPCION

CONCEPCION, Chile

1
José Ulloa

COLABORADOR DOCENTE

DEPARTAMENTO DE QUÍMICA ORGÁNICA

Universidad de Concepción

CONCEPCIÓN, Chile

1
Yesid Tapiero

Docente partime de Química general II

Polímeros

Universidad de Concepción

Concepción, Chile

1
Eduardo Berrios

Profesor auxiliar

Instituto de Química y Bioquímica

UNIVERSIDAD DE VALPARAISO

Valparaíso, Chile

1
José Pino

Director de Departamento

Medicina

Universidad de Atacama

Copiapó, Chile

1
LUIS AGUILAR

PROFESOR ADJUNTO

FACULTAD DE CIENCIAS

PONTIFICIA UNIVERSIDAD CATOLICA DE VALPARAISO

VALPARAISO, Chile

1
Daniela Andrade

academico

Universidad Austral de Chile

puerto montt , Chile

1
Pilar Parada

Executive Director

Centre for Systems Biotechnology

Fraunhofer Chile Research

Santiago, Chile

1
Víctor Campos

Representante médico

Laboratorios Saval S.A.

Concepción, Chile

1
Juan Staforelli

Académico

Ciencias Físicas

Universidad de Concepción

concepción, Chile

1
Myleidi Vera

Profesor asistente

Departamento de Polímeros

Universidad de Concepción

Concepcion, Chile

1
Jorge Vergara

Profesor asistente

Química Orgánica

Universidad de Concepción

Concepción, Chile