Man

Pablo Andrés Alarcón Uribe

Profesor a honorarios

CFT Santo Tomas

valdivia, Chile

Líneas de Investigación


farmacologia molecular; inmunologia; biologia celular

Educación

  •  Doctorado en Ciencias Mención Biología Celular y Molecular, UNIVERSIDAD AUSTRAL DE CHILE. Chile, 2017

Experiencia Profesional

  •   Asistente de investigación, FONDECYT 1090401 Full Time

    Universidad Austral de Chile

    Chile

    2009 - 2010

  •   Personal de apoyo en laboratorio de biología molecular Full Time

    AQUAGESTION S.A.

    Puerto Montt, Chile

    2009 - 2009

  •   Tesista de Pregrado, FONDEF D04I1240 Full Time

    Universidad Austral de Chile

    Valdivia, Chile

    2008 - 2009

  •   Profesor a honorarios Part Time

    CFT Santo Tomas

    Valdivia, Chile

    2015 - 2018

  •   Tesista de Doctorado, Fondecyt 1120718 Full Time

    Universidad Austral de Chile

    Valdivia, Chile

    2013 - 2016

  •   Investigador Postdoctoral Full Time

    Universidad Austral de Chile

    Valdivia, Chile

    2017 - 2020

  •   Profesor Ad honorem Part Time

    Universidad Austral de Chile

    Valdivia, Chile

    2017 - A la fecha


 

Article (17)

Equine bone marrow-derived mesenchymal stromal cells inhibit reactive oxygen species production by neutrophils
Glycolysis and mitochondrial function regulate the radical oxygen species production induced by platelet-activating factor in bovine polymorphonuclear leukocytes
Oleic and Linoleic Acids Induce the Release of Neutrophil Extracellular Traps via Pannexin 1-Dependent ATP Release and P2X1 Receptor Activation
Searching for Drug Synergy Against Cancer Through Polyamine Metabolism Impairment: Insight Into the Metabolic Effect of Indomethacin on Lung Cancer Cells
Vincristine, carboplatin and cisplatin increase oxidative burst induced by PAF in canine neutrophils
Docosahexaenoic acid and TUG-891 activate free fatty acid-4 receptor in bovine neutrophils
Functional expression of the free fatty acids receptor-1 and-4 (FFA1/GPR40 and FFA4/GPR120) in bovine endometrial cells
Metabolic disturbances in synovial fluid are involved in the onset of synovitis in heifers with acute ruminal acidosis
Pro-inflammatory mediators and neutrophils are increased in synovial fluid from heifers with acute ruminal acidosis
D(-) Lactic Acid-Induced Adhesion of Bovine Neutrophils onto Endothelial Cells Is Dependent on Neutrophils Extracellular Traps Formation and CD11b Expression
Application of a real-time PCR assay to detect BK potassium channel expression in samples from Atlantic salmon (Salmo salar) and Rainbow trout (Oncorhynchus mykiss) acclimated to freshwater
Eimeria bovis-triggered neutrophil extracellular trap formation is CD11b-, ERK 1/2-, p38 MAP kinase- and SOCE-dependent
Oxidative response of neutrophils to platelet-activating factor is altered during acute ruminal acidosis induced by oligofructose in heifers
2-Aminoethoxydiphenyl borate (2-APB) reduces alkaline phosphatase release, CD63 expression, F-actin polymerization and chemotaxis without affecting the phagocytosis activity in bovine neutrophils
2-Aminoethoxydiphenyl borate (2-APB) reduces respiratory burst, MMP-9 release and CD11b expression, and increases l-selectin shedding in bovine neutrophils.
D-lactic acid interferes with the effects of platelet activating factor on bovine neutrophils.
Andrographolide reduces IL-2 production in T-cells by interfering with NFAT and MAPK activation

Proyecto (11)

ROL DE LOS RECEPTORES PURINÉRGICOS Y ATP EN LA ACTIVACIÓN DEL NEUTRÓFILO DE BOVINO INDUCIDO POR NEFAS
LONG CHAIN FATTY ACIDS AS MODULATORS OF BOVINE INNATE IMMUNITY. ROLE OF FREE FATTY ACID (FFA)-1 AND FFA4 RECEPTORS.
LONG CHAIN FATTY ACIDS AS MODULATORS OF BOVINE INNATE IMMUNITY. ROLE OF FREE FATTY ACID (FFA)-1 AND FFA4 RECEPTORS.
CONSOLIDACIÓN E INTERNACIONALIZACIÓN DE LOS PROGRAMAS DE DOCTORADOS PARA AUMENTAR LA COMPETITIVIDAD Y PRODUCTIVIDAD DE LA UACH EN LAS ÁREAS ESTRATÉGICAS DE BIOCIENCIAS, BIOTECNOLOGÍA Y CIENCIAS VETERINARIAS , COMO BASES DEL DESARROLLO SOCIAL Y PRODUCTIVO
Ácido D-láctico modula la formación de NETs (Neutrophils extracellular Traps) y la adhesión del neutrófilo sobre el endotelio vascular.
D-LACTATAEMIA INCREASES THE BOVINE BLOOD NEUTROPHIL ACTIVITY AND IS ASSOCIATED WITH THE EARLY ONSET OF LAMINITIS IN HEIFER WITH ACUTE RUMINAL ACIDOSIS
Inmunidad Innata=> Efecto de la temperatura sobre la función de Neutrófilos Bovinos
D-Lactataemia Increases the Bovine Blood Neutrophil Activity and Is Associated with the Early Onset of Laminitis in Heifer with Acute Ruminal Acidosis
ROLE OF NEUTROPHILS IN THE ONSET OF BOVINE LAMINITIS. STUDY OF ACIDOSIS AS NEUTROPHILS PRIMING INDUCER AGENT
ROLE OF NEUTROPHILS IN THE ONSET OF BOVINE LAMINITIS. STUDY OF ACIDOSIS AS NEUTROPHILS PRIMING INDUCER AGENT
EVALUACION DE LA EFICACIA INMUNOMODULADORA DE UNA COMPOSICION DE LABDANOS DITERPENICOS Y DESARROLLO DE NUEVOS ANALOGOS SINTETICOS

Review (1)

Fatty and hydroxycarboxylic acid receptors: The missing link of immune response and metabolism in cattle
13
Pablo Alarcón

Profesor a honorarios

CFT Santo Tomas

valdivia, Chile

9
Rafael Burgos

FULL PROFESSOR

PHARMACOLOGY AND MORPHOPHYSIOLOGY

UNIVERSIDAD AUSTRAL DE CHILE

VALDIVIA, Chile

8
MARIA HIDALGO

Associate professor

Pharmacology

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

3
María Carretta

Assistant Professor

Faculty of Veterinary Science

Universidad Austral de Chile

valdivia, Chile

2
Carolina Manosalva

Académico Auxiliar categoría 03

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

1
Javier Ojeda

Docente instructor en el INstituto de Ciencias Clínicas Veterinarias.

Universidad Austral de Chile

Valdivia, Chile

1
Francisco Morera

Assistant Professor

Pharmacology

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

1
Anita Plaza

Investigador

Medicina

Universidad Austral de Chile

Valdivia, Chile

1
Ivan Conejeros

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

1
DANTE CACERES

Académico

Programa de Salud Ambiental

ESCUELA DE SALUD PUBLICA, FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

SANTIAGO, Chile

1
Claudio Henríquez

Associate Professor

Farmacology and Morphophysiology

Universidad Austral de Chile

Valdivia, Chile

1
BENJAMIN UBERTI

Assistant Professor

Facultad de Ciencias Veterinarias

Universidad Austral de Chile

Valdivia, Chile

1
Rodrigo Lopez

Profesor Asociado

Facultad de Ciencias Veterinarias

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile