Man

Carolina Marcela Manosalva Altamirano

Académico Asociado categoría 02

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

Líneas de Investigación


Farmacología Molecular; Bilogía Celular

Educación

  •  Doctorado en Ciencias Mención Biología Celular y Molecular, UNIVERSIDAD AUSTRAL DE CHILE. Chile, 2015

Experiencia Académica

  •   Académico Auxiliar categoría 03 Full Time

    UNIVERSIDAD AUSTRAL DE CHILE

    2005 - A la fecha

  •   Académico Full Time

    UNIVERSIDAD AUSTRAL DE CHILE

    Valdivia , Chile

    2008 - A la fecha

Experiencia Profesional

  •   Químico Farmacéutico

    Farmacias Cruz Verde

    Chile

    2005 - 2009

  •   Profesor Adjunto

    Universidad Austral de Chile

    Chile

    2005 - 2006

  •   Profesor adjunto

    Universidad Austral de Chile

    Chile

    2006 - 2006

  •   Profesor adjunto

    Universidad Austral de Chile

    Chile

    2007 - 2007

  •   Académico categoría 04

    Universidad Austral de Chile

    Chile

    2008 - A la fecha

  •   Estudiante de Doctorado

    Justus-Liebig-Universität Gießen

    Alemania

    2012 - 2012

  •   Estudiante de Doctorado

    University of Illinois at Chicago - UIC

    Estados Unidos

    2013 - 2014

  •   Académico Asociado categoría 02 Full Time

    Universidad Austral de Chile

    Valdivia , Chile

    2022 - A la fecha


 

Article (18)

Linoleic Acid Induces Metabolic Reprogramming and Inhibits Oxidative and Inflammatory Effects in Keratinocytes Exposed to UVB Radiation
Bovine tumor necrosis factor-alpha Increases IL-6, IL-8, and PGE2 in bovine fibroblast-like synoviocytes by metabolic reprogramming
D-lactate-induced ETosis in cattle polymorphonuclear leucocytes is dependent on the release of mitochondrial reactive oxygen species and the PI3K/Akt/HIF-1 and GSK-38 pathways
D-lactate-triggered extracellular trap formation in cattle polymorphonuclear leucocytes is glucose metabolism dependent
Role of Lactate in Inflammatory Processes: Friend or Foe
Hydrocortisone decreases metacognitive efficiency independent of perceived stress
Functional expression of the free fatty acids receptor-1 and-4 (FFA1/GPR40 and FFA4/GPR120) in bovine endometrial cells
Metabolic disturbances in synovial fluid are involved in the onset of synovitis in heifers with acute ruminal acidosis
Transcriptional analysis of flagellar and putative virulence genes of Arcobacter butzleri as an endocytobiont of Acanthamoeba castellanii
Fatty and hydroxycarboxylic acid receptors=> the missing link of immune response and metabolism in cattle
D(?) lactic acid-induced adhesion of bovine neutrophils onto endothelial cells is dependent on neutrophils extracellular traps formation and CD11b expression
Differential free fatty acid receptor-1 (FFAR1/GPR40) signalling is associated with gene expression or gelatinase granule release in bovine neutrophils.
Cloning, identification and functional characterization of bovine free fatty acid receptor-1 (FFAR1/GPR40) in neutrophils
Cloning, Identification and Functional Characterization of Bovine Free Fatty Acid Receptor-1 (FFAR1/GPR40) in Neutrophils
Linoleic acid increases adhesion, chemotaxis, granule release, intracellular calcium mobilisation, MAPK phosphorylation and gene expression in bovine neutrophils
Linoleic acid increases adhesion, chemotaxis, granule release, intracellular calcium mobilisation, MAPK phosphorylation and gene expression in bovine neutrophils
Oleic acid induces intracellular calcium mobilization, MAPK phosphorylation, superoxide production and granule release in bovine neutrophils
Oleic acid induces intracellular calcium mobilization, MAPK phosphorylation,superoxide production and granule release in bovine neutrophils

Proyecto (6)

Role of FFA1 receptor agonists on wound healing in aging
D (-) lactic acid triggers Fibroblast-Like Synoviocytes activity, a hallmark in the pathophysiology of neutrophilic polysynovitis in cattle with acute ruminal acidosis
MetaStress=> Mecanismo Hormonal regulador de la capacidad Metacognitiva
Rol de ácido linoleico sobre la producción de quimiocinas en queratinocitos humanos y su impacto en la fase inflamatoria durante la cicatrización de heridas
"Rol del receptor de ácidos grasos GPR40 en la liberación de MMP-9, migración y proliferación de queratinocitos estimulados con ácido oleico y ácido linoleico"
DIFFERENTIAL EFFECT OF NONESTERIFIED FATTY ACIDS SPECIES ON THEPOLYMORPHONUCLEAR LEUKOCYTE FUNCTION IN DAIRY HEIFERS

Review (2)

The D-lactate enigma: exploring the inflammatory influence of D-lactate in cattle
Fatty and hydroxycarboxylic acid receptors: The missing link of immune response and metabolism in cattle
6
MARIA HIDALGO

Associate professor

Pharmacology

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

1
CAROLA OTTH

profesor titular

microbiologia clinica

UNIVERSIDAD AUSTRAL DE CHILE. FACULTAD DE MEDICINA. INSTITUTO DE MICROBIOLOGIA CLINICA

VALDIVIA, Chile

9
Rafael Burgos

FULL PROFESSOR

PHARMACOLOGY AND MORPHOPHYSIOLOGY

UNIVERSIDAD AUSTRAL DE CHILE

VALDIVIA, Chile

1
Marcelo Ratto

Profesor titular

Ciencia Animal

Universidad Austral de Chile

Valdivia, Chile

1
Ivan Conejeros

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

2
Evelyn Jara

Docente/Investigador

Ciencias Básicas

Universidad Santo Tomás

Temuco, Chile

1
Sebastian Brauchi

Associate Professor

Physiology

Universidad Austral de Chile

Valdivia, Chile

2
María Carretta

Assistant Professor

Faculty of Veterinary Science

Universidad Austral de Chile

valdivia, Chile

15
Carolina Manosalva

Académico Asociado categoría 02

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

3
Pablo Alarcón

Profesor a honorarios

CFT Santo Tomas

valdivia, Chile

1
Ricardo Chihuailaf

Académico

Instituto de Ciencias Clínicas Veterinarias

Universidad Austral de Chile

Valdivia, Chile

1
Gabriel Reyes

Profesor Asistente

Psicología

Universidad del Desarrollo

Santiago, Chile

1
Franco Medina

Asistente de Investigación

Psicología

Universidad del Desarrollo

Santiago de Chile, Chile