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Rafael Melo Freire

Academico Investigador

Universidad Central de Chile

Santiago, Chile

Nanomaterials; Nanostructured Materials; Magnetic Nanoparticles; Biomedical applications; Sensing

Chemistry, UNIVERSIDADE FEDERAL DO CEARA. Brasil, 2010
Chemistry, UNIVERSIDADE FEDERAL DO CEARA. Brasil, 2012
Chemistry, UNIVERSIDADE FEDERAL DO CEARA. Brasil

PhD Student Full Time

UNIVERSIDADE FEDERAL DO CEARA

Fortaleza, Brasil

2012 - 2016
Visiting Scholar Full Time

UNIVERSITY OF MASSACHUSETTS AMHERST

Amherst, Estados Unidos

2014 - 2015
Master Student Full Time

UNIVERSIDADE FEDERAL DO CEARA

Fortaleza, Brasil

2010 - 2012
Profesor Part Time

Universidad Autónoma de Chile

Instituto de Ciencias Químicas Aplicadas

Santiago, Chile

2020 - 2021

Investigador Joven Part Time

USACH/CEDENNA

Santiago, Chile

2019 - A la fecha
Investigador Full Time

Instituto de Investigaciones Agropecuarias

Santiago, Chile

2021 - 2023
Academico Investigador Full Time

Universidad Central de Chile

Chile

2023 - A la fecha


2-Aminopyrimidine derivatives as potential fluorescent chemosensors for trivalent cations: Structural characterization, photophysical properties, and live-cell imaging Covarrubias A.A.; Cerda D.; Coddou C.; Saldias, M; Villaman D.; Sánchez-González, R; Gonzalez-Diaz, J; Freire R.M.; Riquelme M.; Haase, A; et al. Article ISI (2026)
Bioactive glasses-Iron oxide nanocomposites: Synthesis, characterization and<i> in</i><i> vitro</i> biological performance Batista, Andreia; Valverde, Thalita M.; Silva, Carla C. M.; de Almeida, Katia J.; Mesquita, Aline M.; Andrade, Lidia M.; Costa, Guilherme M. J.; Freire, Rafael M.; Denardin, Juliano C.; Ferreira, Jose M. F.; et al. Article ISI CERAMICS INTERNATIONAL (2026)
Carbon-based nanopigments derived from açai seed residues with tunable optical properties and biofunctional performance de Carvalho, Claudio Jose Reis; Baracho, Pedro Hilton Lima; Carvalho, Francisco Dheyson de Quadro; Lima, Allysson Rocha; Leitao, Antonio Matheus Osterno; Taniguchi, Carlos Alberto Kenji; Mattos, Adriano Lincoln Albuquerque; Freire, Tiago Melo; Carneiro, Samuel Veloso; Santos-Oliveira, Ralph; et al. Article ISI DYES AND PIGMENTS (2026)
Mapping the morphology and thermal stability of AgCo nanoalloys: Composition-driven phase segregation and functional implications Freire, Rafael M.; Rojas, Sebastian; Vermale, Alice; Khelladi, Lilian; Valencia, Felipe J.; Plaza-Alcafuz, Nicolas; Jara, Maryoris; Lisoni, Judit; Rojas-Nunez, Javier; Baltazar, Samuel E. Article ISI JOURNAL OF ALLOYS AND COMPOUNDS (2026)
Tunable hydrogen evolution reaction activity of FeCu nanoalloys controlled by composition da Costa, Victor Moreira; Agostinho, Felipe Ferreira; da Silva Casciano, Paulo Naftali; Freire, Tiago Melo; Ayala, Alejandro Pedro; de Araujo Paschoal, Carlos William; Santos-Oliveira, Ralph; Freire, Rafael Melo; Denardin, Juliano Casagrande; Andrade Neto, Davino Machado; et al. Article JOURNAL OF ALLOYS AND COMPOUNDS (2026)
Core-shell or Janus-like Fe 0.5 Ni 0.5 nanostructures: A theoretical and experimental study Rojas-Nunez J.; Freire, R. M.; Elias, A. L.; Fujisawa K.; Troncoso, L.; Denardin, J. C.; Plaza-Alcafuz, N.; Baltazar, S. E. Article ISI SCOPUS Journal of Materials Research and Technology (2025)
Evaluation of the effect on antimicrobial properties, color, roughness and curing time of glass ionomer cement incorporated with silver and copper nanoparticles Lima L.A.; Regis, WFM; Lima, FRL; Noronha V.T.; de Paula, AJ; Sousa, FF; Silva, PGB; Freire R.M.; Rodrigues, LKA Article ISI SCOPUS Discover Materials (2025)
Multifunctional sensing of cobalt ions and methylcobalamin using doped Carbon Quantum Dots Oliveira, CMP; Lima, FEH; Lopes G.S.; Matos W.O.; Antunes R.A.; Neto M.L.A.; Moura T.A.; Paschoal A.R.; Cesar, CL; Carvalho, HF; et al. Article ISI SCOPUS Microchemical Journal (2025)
Phenol and chromone compounds for in silico inhibition of nsP2 and nsP3 of Chikungunya virus Oliveira Lima; J.P.; Alexandre Roberto; C.H.; da Rocha; M.; Moreira de Oliveira; V.; Freire; R.M.; Santos-Oliveira; R.; Marinho; E.S.; de Lima Neto; P.; Almeida Fechine; P.-B. Article SCOPUS Pharmaceutical Science Advances (2025)
Tunable dielectric and microwave properties of epoxy composites with cofe2o4 and mgfe2o4 spinel ferrites Araújo, EV; Campos, RVB; Silva, MAS; Sombra A.S.B.; Alencar L.M.R.; de Menezes, AS; Santos-Oliveira R.; Gomes, DG; Denardin J.C.; Freire R.M.; et al. Article ISI SCOPUS Applied Physics A: Materials Science and Processing (2025)
Advances in surface design and biomedical applications of magnetic nanoparticles Araujo, E. V.; Neto, D. M. A.; Freire, T. M.; Costa, V. M.; Clemente, C. S.; dos Santos, J. C. S.; Rocha, Janaina S. Article ISI SCOPUS Advances in Colloid and Interface Science (2024)
Carbon quantum dots with ultra-high quantum yield for versatile turn-on sensor of gluten and cyanide Ions Oliveira J.J.P.; Carneiro S.V.; Carvalho, EF; Rodrigues V.S.F.; Lima, FEH; Matos W.O.; Fechine L.M.U.D.; Antunes R.A.; Neto M.L.A.; Campos, ATP; et al. Article ISI SCOPUS Dyes and Pigments (2024)
FeCo@hydrochar nanocomposites as efficient peroxymonosulfate activator for organic pollutant degradation de Menezes; F.L.; Freire; T.M.; do Nascimento; C.P.G.; Fechine; L.M.U.D.; da Costa; V.M.; Freire; R.M.; Longhinotti; E.; O Nascimento; J.H.O.; Denardin; J.C.; Fechine; et al. Article SCOPUS Environmental Science and Pollution Research (2024)
L-cysteine-coated magnetite nanoparticles as a platform for enzymes immobilization: Amplifying biocatalytic activity of Candida antarctica Lipase A de Menezes F.L.; Freire T.M.; Monteiro, RRD; Antunes R.A.; Melo, RLF; Freire R.M.; dos Santos J.C.S.; Fechine P.B.A. Article ISI SCOPUS Materials Research Bulletin (2024)
Multichannel Sensor for Detection of Molybdenum Ions Based on Nitrogen-Doped Carbon Quantum Dot Ensembles Cruz A.A.C.; Souza, NDG; de Souza, JPB; Carneiro S.V.; Clemente C.S.; Sousa, JS; Fechine L.M.U.D.; Michea S.; Fechine P.B.A.; Freire R.M. Article ISI SCOPUS C-Journal of Carbon Research (2024)
Determination of Co2+ ions in blood samples: A multi-way sensing based on NH2-rich carbon quantum dots Antunes, R. A.; Neto, M. L. A.; Cesar, C. L.; Carvalho, H. F.; Lopes, G. S. Article ISI SCOPUS Dyes and Pigments (2023)
Straightforward synthesis of monodisperse Co/Zn-based nanoparticles and their antifungal activities on Botrytis cinerea Freire, Rafael M. M.; Infante, Claudia D. D.; Denardin, Juliano C. C.; Michea, Sebastian Article ISI SCOPUS AIP Advances (2023)
Graphene and its derivatives: understanding the main chemical and medicinal chemistry roles for biomedical applications Magne, Tais Monteiro; de Oliveira Vieira, Thamires; Alencar, Luciana Magalhaes Rebelo; Maia Junior, Francisco Francine; Gemini-Piperni, Sara; Carneiro, Samuel V.; Golokhvast, Kirill; Metrangolo, Pierangelo; Santos-Oliveira, Ralph Article ISI SCOPUS Journal of Nanostructure in Chemistry (2022)
Magnetic FeM (M = Ag, Co, Cu, and Ni) nanocrystals as electrocatalysts for hydrogen evolution reaction Melo Freire, Rafael; Oliveira, F. G.S.; Casciano, P. N.S.; Fechine, Pierre B.A. Article SCOPUS Materials Today Sustainability (2022)
Silica Nanoparticles Modified with Fluorescent Dyes as Probes for in Situ Characterization of Natural Rubber Coatings Oliveira, Naiara C.; Paula, Amauri J.; Maia, Marcella T.; Noronha, Victor T.; Alves, Ana C.; Filho, Antonio G. Souza; Faria, Andreia F.; do Nascimento, Rodney M. Article ISI SCOPUS ACS Applied Nano Materials (2022)
A novel amino phosphonate-coated magnetic nanoparticle as MRI contrast agent Neto, Davino M. A.; da Costa, Luelc S.; de Menezes, Fernando L.; Banobre-Lopez, Manuel; Vasconcelos, Igor F.; Ribeiro, Thiago S.; Leal, Luzia Kalyne A. M.; de Sousa, Joao A. C.; Gallo, Juan Article ISI SCOPUS APPLIED SURFACE SCIENCE (2021)
Coercivity dependence of cation distribution in Co-based spinel: correlating theory and experiments Article ISI SCOPUS Inorganic Chemistry Frontiers (2021)
Highly sensitive sensing of food additives based on fluorescent carbon quantum dots Carneiro, S., V; Holanda, M. H. B.; Cunha, H. O.; Oliveira, J. J. P.; Pontes, S. M. A.; Cruz, A. A. C.; Fechine, L. M. U. D.; Moura, T. A.; Paschoal, A. R.; Zambelli, R. A. Article ISI SCOPUS Journal of Photochemistry and Photobiology A: Chemistry (2021)
Hydroxyapatite-Based Magnetic Bionanocomposite as Pharmaceuticals Carriers in Chitosan Scaffolds Chaves, Anderson Valerio; Feitosa, Victor Pinheiro; Ricardo, Nagila Maria Pontes Silva Article ISI SCOPUS Journal of Composites Science (2021)
New nanocomposite made of cashew apple bagasse lignin and Fe3O4 for immobilizing of lipase B from Candida antarctica aiming at esterification Serpa, Juliana de Franca; Matias, Gabriel A. B.; da Costa, Victor M.; Goncalves, Luciana R. B.; de Macedo, Andre C.; Rocha, Maria V. P. Article ISI SCOPUS Journal of Chemical Technology and Biotechnology (2021)
Organophosphorus halloysite nanotubes as adsorbent for lead preconcentration in wine and grape juice Santana, Allan M.; da Silva, Francisco L. F.; Ramos, Lauren L.; Cavalcante, Giovanna R.; Vieira, Lais H. S.; Ferreira, Odair P.; Lopes, Gisele S.; Matos, Wladiana O. Article ISI SCOPUS Applied Clay Science (2021)
Starch-based magnetic nanocomposite for targeted delivery of hydrophilic bioactives as anticancer strategy Sousa, Alexandre C. C.; Almeida, Raimundo R.; Silva, Aierta C. C.; Fechine, Lillian M. U.; Brito, Debora H. A.; Pinheiro, Daniel P.; Silva, Larissa M. R.; Pessoa, Otilia D. L.; Pessoa, Claudia Article ISI SCOPUS Carbohydrate Polymers (2021)
Structural, morphological and magnetic properties of iron oxide thin films obtained by atomic layer deposition as a function of their thickness Celis, Freddy Article ISI SCOPUS JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS (2021)
From Magneto-Dielectric Biocomposite Films to Microstrip Antenna Devices de Menezes, Fernando Lima; Andrade Neto, Davino Machado; Rodrigues, Maria do Livramento Linhares; Lima, Helder Levi Silva; Paiva, Denis Valony Martins; da Silva, Marcelo Antônio Santos; Fechine, Lillian Maria Uchôa Dutra; Sombra, Antônio Sérgio Bezerra; Rosa, Morsyleide de Freitas; de Souza Filho, Men de Sá Moreira Article ISI SCOPUS Journal of Composites Science (2020)
Lipase FromRhizomucor mieheiImmobilized on Magnetic Nanoparticles: Performance in Fatty Acid Ethyl Ester (FAEE) Optimized Production by the Taguchi Method Moreira, Katerine S.; Rocha, Thays N.; Michea, Sebastian Article ISI SCOPUS Frontiers in Bioengineering and Biotechnology (2020)
Magnetic Porous Controlled Fe3O4-Chitosan Nanostructure: An Ecofriendly Adsorbent for Efficient Removal of Azo Dyes Queiroz, Danilo C.; Ricardo, Nagila M. P. S.; Rodrigues, Thaina N. B.; Gondim, Diego R.; Junior, Ivanildo J. S. Article ISI SCOPUS Nanomaterials (2020)
Natural arrangement of AgCu bimetallic nanostructures through Oleylamine reduction Freire, Rafael; Elías, Ana Laura; Fujisawa, Kazunori; Baltazar, Samuel E. Article ISI SCOPUS Inorganic Chemistry Frontiers (2020)
Fluorescence Based Platform to Discriminate Protein Using Carbon Quantum Dots Carneiro?Cruz, Antônio Alvernes; Freire, Rafael Melo; Froelich, Diese Beatiz; Alves?de?Lima, Ari Clesius; Muniz, André Rodrigues; Ferreira, Odair Pastor Article ISI SCOPUS CHEMISTRYSELECT (2019)
Probing the Defect-Induced Magnetocaloric Effect on Ferrite/Graphene Functional Nanocomposites and their Magnetic Hyperthermia Angel Gracia-Pinilla, Miguel; Vinicius-Araujo, Marcus; Bakuzis, Andris F. Article ISI SCOPUS JOURNAL OF PHYSICAL CHEMISTRY C (2019)
Sensing strategy based on Carbon Quantum Dots obtained from riboflavin for the identification of pesticides Carneiro S.V.; de Queiroz V.H.R.; Cruz A.A.C.; do Nascimento R.F. Article ISI SCOPUS SENSORS AND ACTUATORS B-CHEMICAL (2019)