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Joel Gustavo Cabezas Salazar

Ph.D. in Veterinary Sciences

Universidad de Concepción

Chillan , Chile

Estudio de la inmunobiología de las células madre mesenquimales equinas derivadas de tejido adiposo, características biológicas en cultivo, expresión de marcadores, priming in vitro y secretoma asociado a fenotipo inmunomodulador

Médico Veterinario, UNIVERSIDAD DE CONCEPCION. Chile, 2015
Ciencias Veterinarias , UNIVERSIDAD DE CONCEPCION. Chile, 2018

Asistente de investigación Part Time

UNIVERSIDAD DE CONCEPCION

Medicina Veterinaria

Chillan , Chile

2012 - 2014
Asistente de Investigación Full Time

UNIVERSIDAD DE CONCEPCION

Medicina Veterinaria

Chillan , Chile

2014 - 2017
Ph.D en Ciencias Veterinarias Full Time

UNIVERSIDAD DE CONCEPCION

Ciencias Veterinarias

Chillan, Chile

2014 - 2018

Profesor de Cultivo celular y tejidos animales Part Time

UNIVERSIDAD CATÓLICA DEL MAULE

Talca, Chile

2015 - 2017
Profesor de Interacciones patogénicas en organismos superiores Part Time

UNIVERSIDAD CATÓLICA DEL MAULE

TAlca, Chile

2016 - 2017
Profesor de Reproducción de Animales Mayores Part Time

UNIVERSIDAD SANTO TOMAS

Concepción, Chile

2018 - 2018

Beca Erasmus

UNIVERSIDAD DE CORDOBA

España, 2017

Estancia en instalaciones del IMIBIC en Córdoba España, por un período de 3 meses, realizando labores de cultivo celular e investigación en células madre derivadas de médula ósea humana en Diabetes.
VIU (Valorización de la Investigación en la Universidad)

FONDEF

Chile, 2011

Gano concurso del primer VIU otorgado por Fondef en el año 2011, el cual lo desarrollo en establecer un nexo entre la investigación básica y la aplicación clínica de células madre mesenquimales en patologías veterinarias.


Assessment of the anti-inflammatory and engraftment potential of horse endometrial and adipose mesenchymal stem cells in an in vivo model of post breeding induced endometritis Article ISI Theriogenology (2020)
Complimentary diagnostic tools for endometrosis in biopsies of mares with clinical subfertility Rojas D.; Cabezas J.; RamÃƒÂrez G.; Saravia F.; Rodriguez-Ãlvarez L.; Castro F.O. Article ISI Acta Scientiae Veterinariae (2020)
Distinctive Cellular Transcriptomic Signature and MicroRNA Cargo of Extracellular Vesicles of Horse Adipose and Endometrial Mesenchymal Stem Cells from the Same Donors Yat Sen Wong; Riadi, Gonzalo; Daniela Rojas Mansilla; Rodriguez, Lleretny; Castro, Fidel O. Article CELLULAR REPROGRAMMING (2020)
Edition of Prostaglandin E2 Receptors EP2 and EP4 by CRISPR/Cas9 Technology in Equine Adipose Mesenchymal Stem Cells Article ISI Animals (2020)
Genomic Evaluation of Primiparous High-Producing Dairy Cows: Inbreeding Effects on Genotypic and Phenotypic Production–Reproductive Traits Miguel Gutierrez Reinoso; Manuel Garcia-Herreros Article Animals (2020)
In vitro preconditioning of equine adipose mesenchymal stem cells with prostaglandin E2, substance P and their combination changes the cellular protein secretomics and improves their immunomodulatory competence without compromising stemness Wong Y. Article ISI Veterinary Immunology and Immunopathology (2020)
Differentiation and multipotential characteristics of mesenchymal stem cells derived from adipose tissue of an endangered wild cat (Leopardus guigna) Diana M. Echeverry; Daniela M. Rojas; Constanza J. Aguilera; Daniel M. Veraguas; Joel G. Cabezas; Lleretny Rodríguez-Álvarez; Fidel O. Castro Article ISI SCIELO SCOPUS AUSTRAL JOURNAL OF VETERINARY SCIENCES (2019)
Extracellular vesicles secreted during blastulation show viability of bovine embryos Briones M.A. Article ISI SCOPUS REPRODUCTION (2019)
The expression level of SOX2 at the blastocyst stage regulates the developmental capacity of bovine embryos up to day-13 of in vitro culture ManrÃquez J.; RodrÃguez-Alvarez L.L. Article ISI SCOPUS ZYGOTE (2019)
Equine mesenchymal stem cells derived from endometrial or adipose tissue share significant biological properties, but have distinctive pattern of surface markers and migration Article ISI SCOPUS Theriogenology (2018)
A Case of Complete Resealing of Patent Foramen Ovale in a Cloned Red Angus Calf Cofre S.; VelÃ¡squez A.E.; Torres A.; Cabezas J.; Cox, JF Article . Journal Stem Cell Research Transplantation (2017)
Endometritis and In Vitro PGE(2) Challenge Modify Properties of Cattle Endometrial Mesenchymal Stem Cells and Their Transcriptomic Profile Cabezas, Joel; Rivera, Nathaly; Pacha, Paulina; Rodriguez-Alvarez, Lleretny Article ISI SCOPUS Stem Cells International (2017)
Identification and characteristics of extracellular vesicles from bovine blastocysts produced in vitro Mellisho E.A.; Cabezas J.G.; Cueto J.A.; Fader C. Article ISI SCOPUS PLOS ONE (2017)
Combined use of platelet rich plasma and vitamin C positively affects differentiation in vitro to mesodermal lineage of adult adipose equine mesenchymal stem cells Torres A.; Cabezas J.; Rodriguez-Alvarez L.L. Article ISI RESEARCH IN VETERINARY SCIENCE (2014)
The Endometrium of Cycling Cows Contains Populations of Putative Mesenchymal Progenitor Cells Cabezas J.; Lara E.; Pacha, P; Rojas D.; Veraguas D.; Saravia F.; Rodriguez-Ãlvarez L. Article ISI SCOPUS REPRODUCTION IN DOMESTIC ANIMALS (2014)


207 Editing of prostaglandin E2 gene receptors EP2 and EP4 by CRISPR/Cas9 technology in equine adipose mesenchymal stem cells Furlanetto Ana Carolina; Daniela Rojas Mansilla ConferencePoster (2020)
52 Blocking of embryonic development by nanoparticles derived from endometrial and oviductal cells isolated with an Amicon filter system Daniela Rojas Mansilla; Pedro Silva; Gutierrez, Miguel ConferencePoster (2020)
79 MicroRNAs of extracellular vesicles secreted by embryos as an early biomarker of competence Bárbara Melo-Baez; Yat Sen Wong; Constanza Aguilera ConferencePoster (2020)
185 Overexpression or CRISPr/Cas9-mediated inhibition of prostaglandin E2 receptors EP2 and EP4 in equine adipose mesenchymal stem cells: implications for cell migration and cellular therapies Furlanetto Ana Carolina; Francisca Telleria ConferencePoster (2019)
DYNAMIC CHANGES IN BOVINE ENDOMETRIAL STEM CELLS THROUGHOUT ESTRUS CYCLE AND POSTPARTURITION Lara, Evelyn; Nathaly Rivera ConferencePoster (2018)
Seed oil from Pinus radiate promotes beneficial morphological and inflammatory changes in visceral adipose tissue from high-fat diet-induced obese mice Daniela Rojas Mansilla; Duran Sandoval, Daniel Andres ConferencePoster (2018)
La presencia y funcionalidad de células madre mesenquimales endometriales bovinas varia a lo largo del ciclo estral Nathaly Rivera; Lara, Evelyn ConferencePoster (2017)
Uma técnica simples para quantificar a apoptose de oócitos maturados in vitro em vacas VelÃ¡squez A.E.; Mellisho, E; Cabezas J. ConferencePoster (2016)
Correlation between secreted prostaglandin E2 and prostaglandin E synthetase mRNA expression in equine adipose-derived mesenchymal stem cells Manriquez J.; Silva P.; Cabezas J. ConferencePoster (2015)
Evaluation of surface markers on equine adipose MSC by flow cytometry Cabezas J.; Rojas D.; Gallegos P.; Saravia F. ConferencePoster (2015)
Signature of mesenchymal stem cells markers in human gingival cells Cabezas J.; Rojas D.; Gallegos P.; Arriagada V.; Sanchez G. ConferencePoster (2015)
Treatment of tendon injury in sport horses using adipose derived MSC and PRP Cabezas J. ConferencePoster (2015)
Validation of a method for isolating homogeneous populations of cat adipose-derived stem cells (AMSC) Paula Gallegos; Daniela Rojas Mansilla ConferencePoster (2015)
Evaluación de marcadores génicos de pluripotencia e inflamación en endometrio de vacas ciclando Cabezas J.; Torres A.; Veraguas D.; Saravia F.; Rodriguez -Alvarez LL ConferencePoster (2013)
The endometrium of cows as a source of mesenchymal stem cells Cabezas J.; Torres A.; Pacha, P; Rojas D.; Saravia F. ConferencePoster (2013)
Bovine endometrial cells express markers of pluripotence and display osteogenic and chondrogenic differentiation potential in vitro Cabezas J.; Torres A.; Veraguas D.; Rodriguez -Alvarez LL ConferencePoster (2012)
El endometrio uterino de vacas contiene células madre capaces de diferenciarse in vitro a linaje mesodérmico Torres A.; Cabezas J.; Saravia F.; Rojas D.; Pacha, P; Rodriguez -Alvarez LL ConferencePoster (2012)
Un caso de cerrado complete de foramen oval persistente en una ternera clonada de la raza angus Cofre S.; Torres A.; Cabezas J. ConferencePoster (2012)
Mesenchymal stem cells isolated from subcutaneuos fat of a mare display chondrogenic, osteogenic and adipogenic potential Torres A.; Cabezas J.; Rodriguez -Alvarez LL ConferencePoster (2011)


Sistema no invasivo para la predicción de calidad y el diagnóstico genético pre-implantaorio para embriones producidos in vitro Mellisho, E; Cabezas J. Patent (2017)
Procedimiento de preacondicionamiento celular in vitro para la obtención de células madre mesenquimales (MSCs) con características inmunomoduladoras Cabezas J.; Saravia F. Patent


Endometrial stem cells in farm animals: Potential role in uterine physiology and pathology Navarrete F.; RodrÃguez-Alvarez L.; Castro F.O. Review SCOPUS Bioengineering (2018)