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FIDEL OVIDIO CASTRO REBOREDO

DIRECTOR LABORATORIO

UNIVERSIDAD DE CONCEPCIÓN

Chillan, Chile

BIOTECNOLOGIA ANIMAL, CELULAS MADRE, TERAPIAS REGENERATIVAS, REPRODUCCION ASISTIDA, EXOSOMAS

Ciencias Veterinarias, UNIVERSIDAD DE LA HABANA. Cuba, 1993
CIENCIAS AGRICOLAS, ACADEMIA AGRICOLA DE BIELORUSIA. Bielorrusia, 1986
INGENIERO ZOOTECNISTA, ACADEMIA AGRICOLA DE BIELORUSIA. Chile, 1984

PROFESOR TITULAR Full Time

Universidad de Concepción

CIENCIAS VETERINARIAS

Chillán, Chile

2004 - A la fecha
DIRECTOR DEPARTAMENTO BIOTECNOLOGIA ANIMAL Full Time

CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIA

LA HABANA, Cuba

1986 - 2004

DIRECTOR DEPARTAMENTO BIOTECNOLOGIA ANIMAL Full Time

CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIA

LA HABANA, Cuba

1986 - 2004
PROFESOR TITULAR Full Time

UNIVERSIDAD DE CONCEPCION

Chillan, Chile

2004 - A la fecha

Ha sido profesor guía de 8 tesis de doctorado. Patrocinante de 3 FOndecyt Post-doctorados y de 3 COncursos VIU-FONDEF

Ha participado en numerosas conferencias, charlas, notas de prensa etc

Premio Licenciamiento Patentes

UNIVERSIDAD DE CONCEPCION

Chile, 2019

PREMIO EN CL CONCURSO DE PATENTES INSITUCIONALES


Assessment of the anti-inflammatory and engraftment potential of horse endometrial and adipose mesenchymal stem cells in an in vivo model of post breeding induced endometritis Article ISI SCOPUS Theriogenology (2020)
Characterization of mesenchymal stem cells derived from adipose tissue of a cougar (Puma concolor) Maritza Echeverry, Diana; Alejandra Asenjo, Pamela; Michele Rojas, Daniela; Javiera Aguilera, Constanza Article ISI SCOPUS Animal Reproduction (2020)
Complimentary Diagnostic Tools for Endometrosis in Biopsies of Mares with Clinical Subfertility Saravia, Fernando E. Article WoS, ISI, SCOPUS ANIMAL REPRODUCTION (2020)
Edition of Prostaglandin E2 Receptors EP2 and EP4 by CRISPR/Cas9 Technology in Equine Adipose Mesenchymal Stem Cells Article ISI SCOPUS Animals (2020)
In vitro and in vivo development of domestic cat embryos generated by in vitro fertilization after eCG priming and oocyte in vitro maturation Article ISI SCOPUS Theriogenology (2020)
Differentiation and multipotential characteristics of mesenchymal stem cells derived from adipose tissue of an endangered wild cat (Leopardus guigna) Diana M. Echeverry; Daniela M. Rojas; Constanza J. Aguilera; Daniel M. Veraguas; Joel G. Cabezas; Lleretny Rodríguez-Álvarez; Fidel O. Castro Article ISI SCIELO SCOPUS AUSTRAL JOURNAL OF VETERINARY SCIENCES (2019)
Effect of BMP15 and/or AMH during in vitro maturation of oocytes from involuntarily culled dairy cows Mellisho, E Article ISI SCOPUS MOLECULAR REPRODUCTION AND DEVELOPMENT (2019)
Extracellular vesicles secreted during blastulation show viability of bovine embryos Briones M.A. Article ISI SCOPUS REPRODUCTION (2019)
The expression level of SOX2 at the blastocyst stage regulates the developmental capacity of bovine embryos up to day-13 of in vitro culture ManrÃquez J.; RodrÃguez-Alvarez L.L. Article ISI SCOPUS ZYGOTE (2019)
eCG stimulation in domestic cats increases the expression of gonadotrophin-induced genes improving oocyte competence during the non-breeding season Veraguas D.; Cuevas S.R.; Saez-Ruiz D.; Castro F.O. Article ISI SCOPUS Reproduction in Domestic Animals (2018)
Equine mesenchymal stem cells derived from endometrial or adipose tissue share significant biological properties, but have distinctive pattern of surface markers and migration Article ISI SCOPUS Theriogenology (2018)
TIEMPO A PRIMERA DIVISIÓN EMBRIONARIA IN VITRO PUEDE PREDECIR LA CAPACIDAD DE DESARROLLO A BLASTOCISTO EN BOVINOS Article SCIELO Spermova (2018)
Cell cycle synchronization and analysis of apoptosis-related gene in skin fibroblasts from domestic cat (Felis silvestris catus) and kodkod (Leopardus guigna) Gallegos P.F. Article ISI SCOPUS REPRODUCTION IN DOMESTIC ANIMALS (2017)
Characterization of mesenchymal stem cells in bovine endometrium during follicular phase of oestrous cycle Article ISI SCOPUS REPRODUCTION IN DOMESTIC ANIMALS (2017)
Embryo splitting affects the transcriptome during elongation stage of in vitro-produced bovine blastocysts Article ISI SCOPUS Theriogenology (2017)
Endometritis and In Vitro PGE(2) Challenge Modify Properties of Cattle Endometrial Mesenchymal Stem Cells and Their Transcriptomic Profile Cabezas, Joel; Rivera, Nathaly; Pacha, Paulina; Rodriguez-Alvarez, Lleretny Article ISI SCOPUS Stem Cells International (2017)
FSH stimulation of anestrous cats improves oocyte quality and development of parthenogenetic embryos Gallegos P.F. Article ISI SCOPUS Theriogenology (2017)
Identification and characteristics of extracellular vesicles from bovine blastocysts produced in vitro Mellisho E.A.; Cabezas J.G.; Cueto J.A.; Fader C. Article ISI SCOPUS PLOS ONE (2017)
Splitting of IVP bovine blastocyst affects morphology and gene expression of resulting demi-embryos during in vitro culture and in vivo elongation VelÃ¡squez A.E.; Veraguas D.; Cox, JF; Lara E.; Briones M.; Rodriguez-Ãlvarez L. Article ISI ZYGOTE (2016)
Transient Expression of Functional Glucocerebrosidase for Treatment of Gaucher's Disease in the Goat Mammary Gland Tavares K.C.S.; Dias, ACD; Lazzarotto, CR; Neto, SG; Carneiro, ID; Ongaratto, FL; Pinto, AFM; de Aguiar, LH; Calderon, CEM; Santos, DS; et al. Article ISI SCOPUS MOLECULAR BIOTECHNOLOGY (2016)
Clinical spectrum of chronic inflammatory demyelinating polyradiculoneuropathy (cidp) in a chilean pediatric cohort Vargas, C. P.; Castro F.; Varela, X; Ferrando, C. Article ISI JOURNAL OF THE NEUROLOGICAL SCIENCES (2015)
Combined use of platelet rich plasma and vitamin C positively affects differentiation in vitro to mesodermal lineage of adult adipose equine mesenchymal stem cells Torres A.; Cabezas J.; Rodriguez-Alvarez L.L. Article ISI RESEARCH IN VETERINARY SCIENCE (2014)
Prevalence and phylogenetic analysis of honey bee viruses in the Biobio Region of Chile and their association with other honey bee pathogens Rodriguez M.; Vargas M.; Antunez, K.; Gerding M.; Zapata N. Article ISI SCOPUS CHILEAN JOURNAL OF AGRICULTURAL RESEARCH (2014)
The Endometrium of Cycling Cows Contains Populations of Putative Mesenchymal Progenitor Cells Cabezas J.; Lara E.; Pacha, P; Rojas D.; Veraguas D.; Saravia F.; Rodriguez-Ãlvarez L. Article ISI SCOPUS REPRODUCTION IN DOMESTIC ANIMALS (2014)
Constitutive expression of the embryonic stem cell marker OCT4 in bovine somatic donor cells influences blastocysts rate and quality after nucleus transfer Rodriguez-Ãlvarez L.; Manriquez J.; VelÃ¡squez A. Article ISI SCOPUS In Vitro Cellular and Developmental Biology - Animal (2013)
Effect of zona pellucida removal on early development of in vitro produced bovine embryos VelÃ¡squez A.E.; Manríquez, JR; Rodriguez-Alvarez L.L. Article ISI SCIELO SCOPUS ARCHIVOS DE MEDICINA VETERINARIA (2013)
Feasibility of 3-Dimensional Sonographic Examination of the Fetal Secondary Palate During the Second-Trimester Anatomy Scan Sepulveda W.; Wong A.E.; Castro F.; Adiego B.; Martinez-Ten, P Article ISI SCOPUS Journal of Ultrasound in Medicine (2011)
All roads lead to milk: Transgenic and non-transgenic approaches for expression of recombinant proteins in the mammary gland Castro F.O.; Toledo J.R. Article SCOPUS Acta Scientiae Veterinariae (2010)
Changes in the expression of pluripotency-associated genes during preimplantation and pen-implantation stages in bovine cloned and in vitro produced embryos Rodriguez-Ãlvarez L.; Cox J.; Tovar, H; Einspanier, R Article ISI SCOPUS Zygote (2010)
Differential gene expression in bovine elongated (Day 17) embryos produced by somatic cell nucleus transfer and in vitro fertilization Rodriguez-Ãlvarez L.; Sharbati, J; Sharbati, S; Cox, JF; Einspanier, R Article ISI SCOPUS Theriogenology (2010)
Effect of nucleus transfer on gene expression in bovine embryos during early development Rodriguez-Ãlvarez L.; Castro F.O. Article Animal Reproduction (2010)
MicroRNA expression profiling of elongated cloned and in vitro-fertilized bovine embryos Sharbati, S; Rodriguez-Alvarez L.L.; Cox, JF; Hultschig, C; Einspanier, R Article ISI SCOPUS Theriogenology (2010)
The Impact of Conservation on the Status of the World's Vertebrates Hoffmann M.; Hilton-Taylor C.; Angulo A.; Böhm, M; Brooks T.M.; Butchart S.H.M.; Carpenter, KE; Chanson, J; Collen B.; Cox, NA; et al. Article ISI SCOPUS Science (2010)
The short peritoneal equilibration test in pediatric peritoneal dialysis Cano F.; SÃ¡nchez L.; Rebori, A; Quiroz L.; Delucchi A.; Delgado I.; Aguilar, MA; Azocar M.; Castro F.; Ibacache, MJ; et al. Article ISI SCOPUS Pediatric Nephrology (2010)
Elongation and gene expression in bovine cloned embryos transferred to temporary recipients Rodriguez-Ãlvarez L.; Cox J.; Navarrete F.; Valdés, C; Zamorano T.; Einspanier, R Article ISI SCOPUS ZYGOTE (2009)
Cold storage of biopsies from wild endangered native Chilean species in field conditions and subsequent isolation of primary culture cell lines Tovar, H; Navarrete F.; Rodriguez L.; Skewes O. Article ISI SCOPUS IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL (2008)
High developmental potential in vitro and in vivo of cattle embryos cloned without micromanipulators Rodriguez L.; Navarrete, FI; Tovar, H; Cox, JF Article ISI SCOPUS JOURNAL OF ASSISTED REPRODUCTION AND GENETICS (2008)
Cell confluency is as efficient as serum starvation for inducing arrest in the G0/G1 phase of the cell cycle in granulosa and fibroblast cells of cattle Hayes O.; Ramos B.; Rodriguez, LL; Aguilar A.; Badia, T Article ISI SCOPUS Animal Reproduction Science (2005)
Effect of cryopreservation on fusion efficiency and in vitro development into blastocysts of bovine cell lines used in somatic cell cloning Hayes O.; Rodriguez, LL; Gonzalez A.; Falcon, V; Aguilar A. Article ISI SCOPUS ZYGOTE (2005)


ADENOVIRAL VECTOR-MEDIATED EXPRESSION OF RECOMBINANT HUMAN GLUCOCEREBROSIDASE IN THE MAMMARY GLAND OF RATS Tavares K.C.S.; Feltrin, C.; Carneiro, IS; Morais, AS; Medeiros, CD; SÃ¡nchez O.; Renard, G.; Dias, ACO; Chies, JM; Santos, DS; et al. Abstract ISI Reproduction, fertility, and development (2013)
Bovine endometrial cells express markers of pluripotence and display osteogenic and chondrogenic differentiation potential in vitro Torres A.; Veraguas D.; Rodriguez-Ãlvarez L. Abstract ISI REPRODUCTION IN DOMESTIC ANIMALS (2012)
The expression of pluripotency markers in donor cells increases gene expression variability in bovine cloned embryos Rodriguez-Ãlvarez L.; ManriAquez, J; VelÃ¡squez A. Abstract ISI REPRODUCTION IN DOMESTIC ANIMALS (2012)
CHANGES IN GENE EXPRESSION PATTERN DURING PRE- AND PERI-IMPLANTATION STAGES IN BOVINE CLONED EMBRYOS Rodriguez-Alvarez L.L.; Cox, JF; Einspanier, R Abstract ISI Reproduction, fertility, and development (2010)
REPROGRAMMING OF MICRO RNA IN BOVINE CLONED ELONGATED EMBRYOS Sharbati, S; Rodriguez-Alvarez L.L.; Cox, JF; Hultschig, C; Einspanier, R Abstract ISI Reproduction, fertility, and development (2010)


Journal of pharmacy & pharmacognosy research: For specialists working in the pharmaceutical and herbal fields Valdés X.G.; Vasallo A.; Suárez B.B.G.; De Chaves D.S.A.; Spegazzini E.; Chemat F.; Do Nascimento G.N.L.; Nadinic J.; Isaza-Martínez J.H.; Sepulveda-Arias, JC; et al. Editorial SCOPUS Journal of Pharmacy and Pharmacognosy Research (2017)


METHOD FOR THE PRODUCTION OF RECOMBINANT PROTEINS IN THE MAMMARY GLAND OF NON TRANSGENIC MAMMALS Toledo, Jorge Roberto; Rodriguez Molto P; Castro, Fidel O. Patent (2004)
PROCEDIMIENTO DE PREACONDICIONAMIENTO CELULAR IN VITRO PARA LA OBTENCION DE CELULAS MADRE MESENQUIMALES (MSC) CON CARACTERISTICAS INMUNOMODULADORAS Castro, Fidel O.; Manriquez J. Patent esta patente será licenciada a la OTL-UPI de la Universidad de Concepción para la producción masiva de células madre
Proceso in vitro de manipulación del eje Prostaglandina E2 y sus receptores EP2 y EP4 en células madre mesenquimales equinas (eMSC). Furlanetto Ana Carolina; Castro, Fidel O.; Manriquez J. Patent
SISTEMA NO INVASIVO PARA LA PREDICCION DE CALIDAD Y EL DIAGNOSTICO GENETICO PREIMPLANTATORIO PARA EMBRIONES PRODUCIDOS IN VITRO EDWIN MELLISHO; Castro, Fidel O. Patent


Endometrial stem cells in farm animals: Potential role in uterine physiology and pathology Navarrete F.; RodrÃguez-Alvarez L.; Castro F.O. Review SCOPUS Bioengineering (2018)