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Aline . Carvalho da Silva Xavier

Assistant Professor

Universidad de Santiago de Chile

Región metropolitana, Chile

My research is with medical equipment that produces images to help diagnose diseases (ex. Mammography, Magnetic Resonance, Ultrasound). Research keywords: Biomedical Engineering; Medical Images; Radiology; Magnetic Resonance; Ultrasound.

PhD in Engineering Sciences. Speciality: Biomedical Engineering (Nuclear Magnetic Resonance), PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2020
Master in Energy and Nuclear Tecnologies. Speciality: Image Quality and Dosimetry (Digital Mammography) , Universidade Federal de Pernambuco . Brasil, 2015
Biomedical Engineering, Universidade Federal de Pernambuco . Brasil, 2013

Tutora en Diplomado de Resonancia Magnetica Other

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Chile

2019 - 2020
Profesora Other

Universidad de O'Higgins

Chile

2020 - 2021
Assistent Professor Full Time

UNIVERSIDAD DE SANTIAGO DE CHILE

Faculty of Engineering

Chile

2022 - A la fecha

Service Provider (1 year and 3 months) Part Time

Laboratório de Metrologia das Radiacões Ionizantes

Brasil

2014 - 2015
Professional Internship (6 months) Full Time

Centre Hospitalier Sainte Anne

Francia

2012 - 2012
Professional Internship (5 months) Part Time

Empresa Brasileira de Engenharia Médica

Brasil

2011 - 2011
Research Student (two and a half years) Part Time

Centro Regional de Ciencias Nucleares

Brasil

2009 - 2011
Postdoctoral Researcher Full Time

Universidad de O'Higgins

Chile

2020 - 2022

1 alumna de magister y dos de pregrado

He participado regularmente en las actividades de difusión y presentación de avances durante la ejecución del CONICYT-PIA Anillo ACT 141, Núcleo Milenio Cardio MR y actualmente del Instituto IHealth. También participé activamente en actividades de difusión de la ciencia a la comunidad, realizando seminarios a alumnos de 4to. Medio invitados a conocer la relación que hay entre Ingeniería, Medicina y Ciencias Biológicas.
Actualmente tengo videos en YouTube de mi investigación y contribuyo con contenido para instragram de los proyectos. Además, soy la representante de ingenieria biomédica (coordinadora) en el comité de vinculación con el medio de la USACH.

First place banner presentation

FACIPE

Brasil, 2014

III encontro científico de radiologia
First place in master selection

Universidade Federal de Pernambuco

Brasil, 2013

Before start the master in the universidade federal de pernambuco they make a selection of students and I earned the first palce
Research Student Scholarship CNPq 117571&119253

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Brasil, 2009

During two and a half years I had a scholarship from CNPq to perform research at Centro Regional de Ciencias Nucleares. 20h per week (01/2019 untill 07/2011).
CAPES/BRAFITEC 3121\11-9 (Internship in France)

CAPES\BRAFITEC

Brasil, 2011

INTERNSHIP I earned a scholarship to study in France for one year (Université de Technologie de Compiègne)
FACEPE IBPG-0045-3.09\12 (Master degree)

Fundação de Amparo a Ciência e Tecnologia de PE (FACEPE)

Brasil, 2013

Scholarship to do a Master at Federal University of Pernambuco (UFPE)
CONICYT folio 21160835

COMISION NACIONAL DE INVESTIGACION CIENTIFICA Y TECNOLOGICA

Chile, 2016

Scholarship to do the PhD at Pontificia Universidad Catolica de Chile
FONDECYT PostDoc

Universidad de O'Higgins

Chile, 2021

Proyecto de PostDoc 2021-2024 FONDECYT ANID 3210458


Characterization of hepatic fatty acids using magnetic resonance spectroscopy for the assessment of treatment response to metformin in an eNOS(-/-) mouse model of metabolic nonalcoholic fatty liver disease/nonalcoholic steatohepatitis Lavin, Begona; Eykyn, Thomas R.; Phinikaridou, Alkystis; Xavier, Aline; Kumar, Shravan; Buque, Xabier; Aspichueta, Patricia; Sing-Long, Carlos; Arrese, Marco; Botnar, Rene M.; Andia, Marcelo E. Article ISI NMR IN BIOMEDICINE (2023)
Characterization of hepatic fatty acids using magnetic resonance spectroscopy for the assessment of treatment response to metformin in an eNOS−/− mouse model of metabolic nonalcoholic fatty liver disease/nonalcoholic steatohepatitis Lavin, B., Eykyn, T. R., Phinikaridou, A., Xavier, A., Kumar, S., Buqué, X., ... & Andia, M. E. Article ISI https://doi.org/10.1002/nbm.4932 NMR IN BIOMEDICINE (2023)
Characterization of Direct Localization Algorithms for Ultrasound Super-Resolution Imaging in a Multibubble Environment: A Numerical and Experimental Study Xavier, Aline; Alarcon, Hector; Espindola, David Article ISI IEEE ACCESS (2022)
Assessment of hepatic fatty acids during non-alcoholic steatohepatitis progression using magnetic resonance spectroscopy Xavier, Aline; Zacconi, Flavia; Santana-Romo, Fabian; Eykyn, Thomas R.; Lavin, Begona; Phinikaridou, Alkystis; Botnar, Rene; Uribe, Sergio; Esteban Oyarzun, Juan; Cabrera, Daniel; Arrese, Marco; Andia, Marcelo E. Article ISI ANNALS OF HEPATOLOGY (2021)
Comparison of localization methods in super-resolution imaging Xavier, Aline; Pinton, Gianmarco; Espindola, David; IEEE Article ISI 2021 IEEE UFFC LATIN AMERICA ULTRASONICS SYMPOSIUM (LAUS) (2021)
Lipoprotein receptor SR-B1 deficiency enhances adipose tissue inflammation and reduces susceptibility to hepatic steatosis during diet-induced obesity in mice Rivera, Katherine; Quiñones, Verónica; Amigo, Ludwig; Santander, Nicolás; Salas-Pérez, Francisca; Xavier, Aline; Fernández-Galilea, Marta; Carrasco, Gonzalo; Cabrera, Daniel; Arrese, Marco; Busso, Dolores; Andia, Marcelo E; Rigotti, Attilio Article Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids (2021)
Metabolite cycled liver H-1 MRS on a 7 T parallel transmit system Xavier, Aline; de Castro, Catalina Arteaga; Andia, Marcelo E; Luijten, Peter R.; Klomp, Dennis W.; Fillmer, Ariane; Prompers, Jeanine J. Article ISI NMR IN BIOMEDICINE (2020)
ESMRMB 2019, 36th Annual Scientific Meeting, Rotterdam, NL, October 3-October 5: Abstracts, Thursday [Anonymous] Article ISI MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE (2019)
Intrahepatic fatty acids composition as a biomarker of NAFLD progression from steatosis to NASH by using H-1-MRS Xavier A.; Zacconi F.; Gainza C.; Cabrera D.; Arrese M.; Uribe S.; Sing-Long C.; Andia M.E. Article ISI SCOPUS RSC ADVANCES (2019)
Study on patient dosimetry and image quality in digital mammography Xavier, Aline Carvalho da Silva; Andrade, Marcos Ely Almeida; Pinto, Beatriz Villa-Chan Cantalupo; Barros, Vinícius Saito Monteiro de; Kramer, Richard; Khoury, Helen Jamil Article ISI Research on Biomedical Engineering (2017)
Dosimetric evaluation of X-ray examinations of paranasal sinuses in pediatric patients [Avaliação dosimétrica de pacientes pediátricos submetidos a exames radiográficos de seios paranasais] Cantalupo B.L.V.-C.; Xavier A.C.S.; da Silva C.M.L.; Andrade M.E.A.; de Barros V.S.M.; Khoury H.J. Article ISI SCOPUS Radiologia Brasileira (2016)
Metodologia para calibração do detector de NaI(Tl) 3 x3 para medições in vivo em pacientes submetidos a radioiodoterapia e indivíduos ocupacionalmente expostos ao 131I. Xavier, Aline; Lacerda, Isabelle; Oliveira, Mércia; Lima, Fabiana; Lima, Fernando. Article Scientia Plena (2012)
Monitoração in vivo dos indivíduos ocupacionalmente expostos na produção de 18FDG no CRCN/NE Lacerda, Isabelle; Xavier, Aline; Oliveira, Mércia; Lima, Fabiana; Lima, Fernando. Article Scientia Plena (2012)


ANTIHYPERTENSIVE AND HYPOGLYCEMIC THERAPY REDUCES BODY AND LIVER FAT DEPOSITION IN A MURINE MODEL OF NON-ALCOHOLIC FATTY LIVER DISEASE (NAFLD) Lavin-Plaza, B; Andia, M; Eykyn, T; Phinikaridou, A; Xavier, A; Botnar, R Abstract ISI ATHEROSCLEROSIS (2019)


Liver fatty acids show gender-specific changes during MAFLD progression in eNOS KO mice. Manjarrés, L.Xavier, A.; Gonzalez, L., Garrido, C., Rivera, K., Zacconi, F.; Sing-Long, C.; Andia, ME ConferencePaper (2023)
Cálculo de los tiempos de relajación de metabolitos hepáticos utilizando espectroscopia por resonancia magnética de 9.4 Tesla Castro, N., Carceres, S., Andia, ME., Xavier, A ConferencePaper (2023)
Cálculo de velocidad de flujo sanguíneo en microvasos a partir de imágenes de super-resolución de placentas ex – vivo Corral, M., Ortiz, V., Krause, B., Espíndola, D. Xavier, A. ConferencePaper (2023)
Magnetic resonance spectroscopy detects the progression of the MAFLD in eNOS KO mice, and it has a gender difference. Manjarrés, L.Xavier, A.; Gonzalez, L., Garrido, C., Rivera, K., Zacconi, F.; Sing-Long, C.; Andia, ME ConferencePaper (2023)
A clustering method to classify stages of NAFLD based on the metabolites results obtained in two mouse models with MRS Xavier, Aline; Gainza, Constanza; Zacconi, Flavia; Cabrera, Daniel; Arrese, Marco; Sing-Long, Carlos; Andia, Marcelo ConferencePaper (2022)
Classifying healthy versus NAFLD mice from liver fatty acids’ 1H- MRS at 9.4 T using SVMs Izquierdo, Pedro; Xavier, Aline; Andia, Marcelo.; Sing-Long, Carlos ConferencePaper (2022)
Super-Resolution Ultrasound Imaging: a Comparison Between Localization Methods Xavier, Aline; Maurera, Gabriel; Krause, Bernardo; Espíndola, David ConferencePaper (2022)
Fatty acids and cholesterol peaks found in MRS are biomarkers of Niemann-Pick C disease diagnosis Xavier, Aline; Zacconi, Flavia; Oyarzun, Juan E.; Zalungo, Silvana; Andia, Marcelo E ConferencePaper (2020)
The use of magnetic resonance spectroscopy and principal component analysis in order to identify the progression of NAFLD Xavier, Aline; Zacconi, Flavia; Gainza, Constanza; Cabrera, Daniel; Arrese, Marco; Uribe, Sergio; Andia, Marcelo E ConferencePaper (2020)
Ex vivo quantification of hepatic fatty acid in mice fed with western-diet using magnetic resonance spectroscopy at 9.4 T Aline Xavier , Flavia Zacconi , Daniel Cabrera , Marco Arese , and Marcelo Andia ConferencePaper (2019)
Hepatic Fatty Acid Profile in Mice with Nonalcoholic Fatty Liver Disease Using Magnetic Resonance Spectroscopy Xavier A.; Zacconi F.; Cabrera D.; Fuenzalida K.; Andia M. ConferencePaper ISI SCOPUS XIV MEDITERRANEAN CONFERENCE ON MEDICAL AND BIOLOGICAL ENGINEERING AND COMPUTING 2016 (2019)
Implementation of metabolite cycled liver 1H MRS on a 7T parallel transmit system. Ariane Fillmer, Catalina Arteaga de Castro, Aline Xavier, Peter R. Luijten, Dennis W. Klomp, Jeanine J. Prompers ConferencePaper (2019)
In vivo and ex vivo quantification of hepatic fatty acid in mice fed with CDAA-diet using magnetic resonance spectroscopy at 9.4 T Xavier, Aline; Zacconi, Flavia; Eykyn, T; Plaza, Begoña; Phinikaridou, Alkystis; Andia, Marcelo. ConferencePaper ISI abstract 10.1007/s10334-019-00753-3 (2019)
In vivo liver pH in eNOS2/2 mice model fed with High Fat Diet may provide clues to understand their susceptible to develop NAFLD Xavier, Aline; Eykyn, T.; Plaza, Begoña; Phinikaridou, Alkystis, Andia, Marcelo. ConferencePaper (2019)
Lipids composition of visceral fat in overweight and obese patients using 1H NMR at 9.4T Xavier, Aline; Zacconi, Flavia; Morelli, Carla; Andia, Marcelo; Uribe, Sergio ConferencePaper (2019)
Towards glycoCEST in the liver at 7T with a multi-transmit system. Aline Xavier , Vitaliy Khlebnikov , Jeanine Prompers , Marcelo Andia , and Catalina Arteaga de Castro. ConferencePaper (2019)
Cholesterol peaks found in MRS are a biomarker of Niemann-Pick disease progression XAVIER, A.C.S; ZACCONI, F. ; ZANLUNGO, S. ; ANDIA, M. E. ConferencePaper (2018)
eNOS-/- mice fed with HFD develop progressive non-alcoholic fatty liver disease (NAFLD) which is partially reversible with antihypertensive and hypoglycemic therapy PLAZA, B. L. ; ANDIA, M. E. ; EYKYN, T. ; PHINIKARIDOU, A. ; Xavier, A. ; BOTNAR, R ConferencePaper (2018)
Fatty acids profile during Non Alcoholic Fat Liver Disease progression using Magnetic Resonance Spectroscopy A. Xavier, F. Zacconi, K. Fuenzalida, S. Uribe, M. Andia ConferencePaper (2017)
Liver Cholesterol is a biomarker of Niemann-pick diseases progression and liver damage and could be quantified with MRS A. Xavier, F. Zacconi, K. Fuenzalida, S. Zanlungo, M. Andia; ConferencePaper (2017)
Perfil de ácidos grasos en injertos hepáticos y renales en un modelo murino de muerte encefálica C. Moreli, R. Rebolledo, P.Achurra, F. Zacconi, A. Xavier, M.Santander, L. Vargas, A. Bruhn, J. Castillo, N. Jarufe. J. Castro ConferencePaper (2017)
Dosimetria de pacientes pediátricos submetidos a exames radiológicos de seios da face. CANTALUPO, B. V. ; XAVIER, A.C.S. ; ANDRADE, M. E. A. ; SILVA, C. M. L. ; MONTEIRO, V. S. ; KHOURY, H. J ConferencePaper (2015)
Patient dosimetry in digital mammography in brazil and costa rica XAVIER, A.C.S.; CANTALUPO, B. V. ; ANDRADE, M. E. A. ; ALVES, F. ; PIRES, S. ; MEDEIROS, R. B. ; MORA, P. ; MONTEIRO, V. S. ; KHOURY, H. J. ConferencePaper (2015)
Avaliação da dose glandular média em sistemas digitais e convencionais de mamografia XAVIER, A.C.S.; MONTEIRO, V. S.; KHOURY, H. J ConferencePaper (2014)
Dosimetria em exames de mamografia em Recife Aline Xavier, Edyelle Oliveira, Marcos Andrade ConferencePaper (2014)
Estimativa do produto erma no ar-area e do erma no ar na superfície de entrada da pele de pacientes pediátricos submetidos à radiografia do tórax CANTALUPO, B. V. ; XAVIER, A.C.S. ; KHOURY, H. J. ; ANDRADE, M. E. A. ; MONTEIRO, V. S ConferencePaper (2014)
Monitoraçlão in vivo dos Indivíduos Ocupacionalmente Expostos ao 18FDG no CRCN/NE Lacerda, IVB ; XAVIER, A.C.S. ; Oliveira, ML ; Lima, F. F. ; LIMA, F. A. ConferencePaper (2011)
Otimização da Metodologia de Monitoração Interna de 18F na Forma de 18FDG Desenvolvida no CRCN-NE. Lacerda, IVB ; OLIVEIRA, C. M. ; XAVIER, A.C.S. ; Lima, F. F. ; Oliveira, ML ; LIMA, F. A. ; SILVA, T. V. ; ALONSO, T. C. ; SILVA, T. A. ConferencePaper (2011)
Otimização da MetodoMetodologia para calibração do detector de NaI(TI) 3 x 3 para medições IN VIVO em pacientes submetidos a Iodoterapia e indivíduos ocupacionalmente expostos ao 131Ilogia de Monitoração Interna de 18F na Forma de 18FDG Desenvolvida no CRCN-NE. XAVIER, A.C.S.; Lacerda, IVB ; Oliveira, ML. ; Lima, F. F. ConferencePaper (2011)
Qualidade de imagem e dose para diferentes combinações tela-filme em mamografia Oliveira, ML; CARVALHO, A.; Lacerda, IVB ; Galindo, RS ; MENEZES, C. J. M . ConferencePaper (2009)


Redes capilares, desprendimiento de geles en prótesis y fractura en minería de roca desde el punto de vista del análisis matemático de problemas de discontinuidad libre Henao, Duvan; Xavier, Aline Proyecto (2023)
INSTITUTO MILENIO EN INGENIERÍA E INTELIGENCIA ARTIFICIAL PARA LA SALUD iHEALTH Prieto, Claudia; Andia, Marcelo Proyecto (2022)
Realidad de las mujeres en las ciencias de la ingeniería en la región de O'higgins Serey, Alejandra; Xavier, Aline Proyecto (2022)
Creacion de imagenes de super-resolucion ultrasonicas en placentas humanas ex vivo Espíndola, David; Xavier, Aline Proyecto (2021)
Optimizing microbubbles localization in ultrasound super-resolution imaging Aline Xavier Proyecto (2021)
NÚCLEO MILENIO DE RESONANCIA MAGNÉTICA CARDIOVASCULAR Sergio Uribe; Andia K, Marcelo Proyecto (2018)
Anillo ACT1416 “Magnetic Resonance Imaging for Aging Related Diseases: Brain, Heart and Vessels” Irarrázaval, Pablo Proyecto (2016)
FATTY ACIDS CHARACTERIZATION DURING NON-ALCOHOLIC FATTY LIVER DISEASE USING MAGNETIC RESONANCE SPECTROSCOPY Aline Xavier Proyecto BECA DOCTORADO NACIONAL CONICYT (2016)
Dosimetría y Calidad de Imagen en Mamografía Digital. FACEPE (Brasil) (Estudiante de Magister) Proyecto 2013-2015 Inv. Principal
Cálculo de la dosis para las pacientes con cáncer de tiroides a través de un estudio anatómico de la tiroides. CNPQ (Brasil) Proyecto 2010-2011 Investigador(a)
Control de la calidad en radiología convencional. CNPQ (Brasil) Proyecto 2009-2010 Investigador(a)

Aline Carvalho da Silva

Assistant Professor

Universidad de Santiago de Chile

Región metropolitana, Chile

Marcelo Andia

Associate Professor

Radiology

Pontificia Universidad Catolica de Chile

Santiago, Chile

Flavia Zacconi

Associate Professor

Organic Chemistry

Pontificia Universidad Católica de Chile

Santiago, Chile

Carlos Sing-Long

Assistant Professor

Instituto de Ingeniería Matemática y Computacional

Pontificia Universidad Católica de Chile

Santiago, Chile

Daniel Cabrera

Investigador Adjunto

Gastroenterología

Pontificia Universidad Catolica de Chile

santiago, Chile

Sergio Uribe

Associated professor

Radiology

PONTIFICIA UNIVERSIDAD CATÓLICA

Santiago, Chile

MARCO ARRESE

FULL PROFESSOR

GASTROENTEROLOGY

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Aline . Carvalho da Silva Xavier

Líneas de Investigación

Educación

PhD in Engineering Sciences. Speciality: Biomedical Engineering (Nuclear Magnetic Resonance), PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2020

Master in Energy and Nuclear Tecnologies. Speciality: Image Quality and Dosimetry (Digital Mammography) , Universidade Federal de Pernambuco . Brasil, 2015

Biomedical Engineering, Universidade Federal de Pernambuco . Brasil, 2013

Experiencia Académica

Tutora en Diplomado de Resonancia Magnetica Other

Profesora Other

Assistent Professor Full Time

Experiencia Profesional

Service Provider (1 year and 3 months) Part Time

Professional Internship (6 months) Full Time

Professional Internship (5 months) Part Time

Research Student (two and a half years) Part Time

Postdoctoral Researcher Full Time

Formación de Capital Humano

Difusión y Transferencia

Premios y Distinciones

First place banner presentation

First place in master selection

Research Student Scholarship CNPq 117571&119253

CAPES/BRAFITEC 3121\11-9 (Internship in France)

FACEPE IBPG-0045-3.09\12 (Master degree)

CONICYT folio 21160835

FONDECYT PostDoc

Article (13)

Abstract (1)

ConferencePaper (30)

Proyecto (11)

Dosimetría y Calidad de Imagen en Mamografía Digital.

Cálculo de la dosis para las pacientes con cáncer de tiroides a través de un estudio anatómico de la tiroides.

Control de la calidad en radiología convencional.