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BARBARA MARIA FRANCISCA MORA LAGOS

Profesor Investigador

Universidad Autónoma de Chile

Temuco, Chile

Líneas de Investigación


Cancer, drug resistance, Cellular and Molecular Biology, epigenetics, Human papillomavirus (HPV)

Educación

  •  Dra. en Ciencias, mención Biología Celular y Molecular Aplicada, UNIVERSIDAD DE LA FRONTERA. Chile, 2020
  •  Biotecnólogo, UNIVERSIDAD DE LA FRONTERA. Chile, 2014

Experiencia Académica

  •   Profesor invitado curso Biotecnología y Biología Molecular (DIB-202) Other

    UNIVERSIDAD DE LA FRONTERA

    Ingeniería y Ciencias

    Temuco, Chile

    2020 - 2020

  •   Profesor invitado curso Genética Evolutiva (ICQ311) Other

    UNIVERSIDAD DE LA FRONTERA

    Ingeniería y Ciencias

    Temuco, Chile

    2018 - 2018

  •   Profesor invitado curso Técnicas de Análisis Avanzado en Biorecursos (BRN600) Other

    UNIVERSIDAD DE LA FRONTERA

    BIOREN

    Temuco, Chile

    2018 - 2018

Experiencia Profesional

  •   Asistente de Investigación Full Time

    Universidad Autónoma de Chile

    Temuco, Chile

    2019 - 2021


 

Article (8)

Resistance to platinum-based cancer drugs: a special focus on epigenetic mechanisms
Epigallocatechin Gallate Enhances MAL-PDT Cytotoxic Effect on PDT-Resistant Skin Cancer Squamous Cells
Functional and transcriptomic characterization of cisplatin-resistant AGS and MKN-28 gastric cancer cell lines
Phylogenetic dating analysis of HTLV-1 from Chile suggests transmissions events related to ancient migrations and contemporary expansion
Loss of ZNF516 protein expression is related with HR-HPV infection and cervical preneoplastic lesions
Gallic acid loaded PEO-core/zein-shell nanofibers for chemopreventive action on gallbladder cancer cells
High-resolution microbiome profiling uncovers Fusobacterium nucleatum, Lactobacillus gasseri/johnsonii, and Lactobacillus vaginalis associated to oral and oropharyngeal cancer in saliva from HPV positive and HPV negative patients treated with surgery and chemo-radiation
Frecuencia de Virus Papiloma Humano en Tumores no Ginecológicos de la Región de la Araucanía, Chile

ConferencePoster (19)

Combination of Poly-3-hydroxybutyrate-microfibers And Gelatin-nanofibers To Mimic The Natural Extracellular Matrix
Functional and transcriptomic characterization of cisplatin-resistant AGS and MKN-28 gastric cancer cell lines.
Establishment of new drug-resistant gastric cancer cell lines.
High-resolution microbiome profiling of 16SrRNA sequencing data, Microbiome Arrays and Expression Arrays identify differential bacterial communities in head and neck cancer patients treated with surgery, chemo-radiation and PD-1 checkpoint blockade therapy.
Characterization of a carboplatin resistance model in A2780 ovarian cancer cell line
Characterization of Long non-coding RNAs associated with drug resistance phenotype in gastric cancer cell lines: preliminary results
Efecto de la citoxicidad y producción de especies reactivas de oxígeno (ROS) de epigalocatequin-galato (EGCG) y gemcitabine (GEM) en líneas celulares de cáncer de vesícula biliar*.
EGCG-coaxial nanofibers for galbladder cancer therapy.
Establishment of a drug-resistant model for detection of down-regulated genes by DNA methylation in gastric cancer.
Finding Genetic markers for EBV classification
Gallic acid loaded PEO-core/ZEIN-shell nanofibers for chemopreventive action.
High-resolution microbiome profiling and genome wide arrays uncover bacteria driven alterations of oncogenic and immune pathways in head and neck cancer patients treated with surgery, chemo-radiation and PD-1 checkpoint blockade therapy.
Identification of differentially hypermethylated genes associated to metastasis in colorectal cancer*.
FKBP6 gene is involved in progression of cervical cancer
ZNF516 a potential tumor suppressor gene candidate is implied in tumor progression in cervical cancer
Determination of Effective Dose (ED50) of Epigallocatechin gallate and Gemcitabine on gallbladder cancer cell lines for their nanoencapsulation.
Epigallocatechin gallate-gemcitabine microcapsules as delivery system for gallbladder cancer treatment*.
FKBP6 gene is involved in viability and colony formation of cervical cancer cells.
Restored expression of ZNF516 in cervical cancer cells decrease cellular viability and colony formation.

Proyecto (5)

Role of the chemokine receptors CCR3 and CXCR2 in chemoresistant gastric cancer: a potential coadjuvant therapy in treatments based on cisplatin and 5-fluorouracil drugs
Nueva formulación farmacológica para el tratamiento de cáncer gástrico: una potencial alternativa en quimioresistencia
Electrospun nanofiber-based epigallocatechin gallate-gemcitabine delivery system
Identification of novel proteins down regulated by DNA methylation capable of been reactivated through ATFs=> An approach to coadjuvant treatment in drug resistant gastric cancer
Caracterización de los genes INTS1 y ZNF516 como oncogenes y potenciales biomarcadores para la detección temprana del cáncer cervicouterino
32
BARBARA MORA

Profesor Investigador

Facultad de Ciencias de la Salud

Universidad Autónoma de Chile

Temuco, Chile

3
Carmen Ili

Investigador y Docente

Scientific and technological Bioresource Nucleus (BIOREN)

UNIVERSIDAD DE LA FRONTERA

Temuco, Chile

2
Priscilla Brebi

Profesor Asociado

Departamento de Anatomía Patológica.

Universidad de La Frontera

Temuco, Chile

1
Mónica Rubilar

Profesor Titular C

Departamento de Ingeniería Química

Universidad de La Frontera

Temuco, Chile

1
Kurt Buchegger

Investigador Postdoctoral

Ciencias Básicas

Universidad de La Frontera

Temuco, Chile

1
Juan Roa

Chair

Pathology

Pontificia Universidad Catolica de Chile

santiago, Chile

1
Claudia Sanhueza

Investigador postdoctoral

Ciencias Básicas

Universidad de La Frontera

Temuco, Chile

1
Irma Fuentes

ACADÉMICO ASISTENTE

Universidad Autónoma de Chile

TEMUCO , Chile

1
Francisca Acevedo

Académico asociado

Ciencias Básicas

UNIVERSIDAD DE LA FRONTERA

Temuco, Chile

1
Jeyson Hermosilla

Asistente de Investigación

Ingeniería Quimica

Universidad de La Frontera

Temuco, Chile

1
Daniela León

Investigador Postdoctoral

Universidad de La Frontera

Temuco, Chile

1
Ismael Riquelme

Académico - Investigador

Ciencias de la Salud

UNIVERSIDAD AUTÓNOMA DE CHILE

Temuco, Chile