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Rajendran Satheeshkumar

Postdoctoral Fellow

Pontificia Universidad Católica de Chile

Pontificia Universidad Católica de Chile, Santiago, Chile, Chile

Organic synthesis, Heterocyclic Chemistry, Catalysis, Medicinal Chemistry, Computational Chemistry, Organometallics and Metal sensing applications

Organic Chemistry, Bharathiar University. India, 2017


Experimental and theoretical physicochemical study of a new dispirocompound: 4 '-(4-fluorophenyl)-2 ',7-dimethyl-1,4-dihydro-3H-dispiro[cyclopent[b]indol-2,5 '-[1,2]oxazinan-6 ' 3 ''-indolin]-2 '',3-dione Satheeshkumar, Rajendran; Montecinos, Rodrigo; Vera, Ariesny; Prasad, Karnam Jayarampillai Rajendra; Kaminsky, Werner; Salas, Cristian O. Article ISI JOURNAL OF MOLECULAR STRUCTURE (2021)
Small interfering RNA for cancer treatment: overcoming hurdles in delivery Charbe, Nitin Bharat; Amnerkar, Nikhil D.; Ramesh, B.; Tambuwala, Murtaza M.; Bakshi, Hamid A.; Aljabali, Alaa A. A.; Khadse, Saurabh C.; Satheeshkumar, Rajendran; Satija, Saurabh; Metha, Meenu; Chellappan, Dinesh Kumar; Shrivastava, Garima; Gupta, Gaurav; Negi, Poonam; Dua, Kamal; Zacconi, Flavia C. Article ISI ACTA PHARMACEUTICA SINICA B (2020)
Water mediated synthesis of 6-amino-5-cyano-2-oxo-N-(pyridin-2-yl)-4-(p-tolyl)-2H-[1,2?-bipyridine]-3-carboxamide and 6-amino-5-cyano-4-(4-fluorophenyl)-2-oxo-N-(pyridin-2-yl)-2H-[1,2?-bipyridine]-3-carboxamide – An experimental and computational studies with non-linear optical (NLO) and molecular docking analyses Jayarajan R.; Satheeshkumar R.; Kottha T.; Subbaramanian S.; Sayin K.; Vasuki G. Article ISI SCOPUS (2020)
Synthesis of Novel Quin[1,2-b]Acridines: In Vitro Cytotoxicity and Molecular Docking Studies Satheeshkumar R.; Edatt L.; Muthusankar A.; Sameer Kumar V.B.; Rajendra Prasad K.J. Article SCOPUS POLYCYCLIC AROMATIC COMPOUNDS (2019)
An expedient synthesis of isoxazolo - and pyrazolo-[3,4-a]acridines with molecular docking studies R. Satheeshkumar, K. Praveenkumar; P. Shanmughavel, K. J. Rajendra Prasad Article Indian Journal of Chemistry Section B, 57B(3), 345-354.2018. (2018)
Synthesis of heteroannulated cyclopent[b]indoles=> Exploration of in vitro cytotoxicity and molecular docking studies R. Satheeshkumar, A. Muthushankar; L. Edatt, V. B. Sameer Kumar; Hazel. A. Sparkes, K. J. Rajendra Prasad Article Synthetic Communications, 48(4), 447-461, 2018. (2018)
Synthesis, spectroscopic, in vitro cytotoxicity and crystal structures of novel fluorinated dispiroheterocycles=> DFT approach R. Satheeshkumar, K. Sayin; W. Kaminsky, K. J. Rajendra Prasad Article Monatshefte für Chemie - Chemical Monthly, 149(1) 141-147, 2018 (2018)
A Facile Regioselective Synthesis of New Class of Cyclopent[b]indole dispiro heterocycles via1,3‐Dipolar Cycloaddition protocol and in vitro Cytotoxic studies R. Satheeshkumar, L. Edatt; V. B. Sameer Kumar, K. J. Rajendra Prasad Article ChemistrySelect, 2(9), 2626-2633, 2017 (2017)
Efficient novel synthesis of pyrano[3,2-a]- and pyrazolo[4,3-a]-acridines R. Satheeshkumar, W. Kaminsky Article Synthetic Communications, 47(3), 245-255, 2017 (2017)
Indium triflate and ionic liquid-mediated Friedländer synthesis of 2-acylquinolines R. Satheeshkumar, K. Sayin; W. Kaminsky, K. J. Rajendra Prasad Article Synthetic Communications, 47(21), 1940-1954, 2017 (2017)
Solvent-free synthesis of dibenzo[b,j][1,10]phenanthroline derivatives using Eaton’s reagent as catalyst R. Satheeshkumar, K. J. Rajendra Prasad Article Synthetic Communications, 47(10), 990- 998, 2017. (2017)
Synthesis, spectral analysis and quantum chemical studies on molecular geometry, chemical reactivity of 7-chloro-9-(2′-chlorophenyl)-2,3-dihydroacridin-4(1H)-one and 7-chloro-9-(2′-fluorophenyl)-2,3-dihydroacridin-4(1H)-one R. Satheeshkumar, K. Sayin; W. Kaminsky, K. J. Rajendra Prasad Article Journal of Molecular Structure, 1128, 279-289, 2017 (2017)
DABCO prompted tandem and multicomponent synthetic protocol of pyrano[2,3-a]acridines R. Satheeshkumar, W. Kaminsky Article Indian Journal of Chemistry Section B, 55B(2), 220-230, 2016 (2016)
Novel Synthetic and Mechanistic Approach of TFA Catalysed Friedländer Synthesis of 2‐Acylquinolines from Symmetrical and Unsymmetrical 1,2‐Diketones with o‐Aminoarylketones R. Satheeshkumar, R. Shankar; Werner Kaminsky, K. J. Rajendra Prasad Article ChemistrySelect, 1(21), 6823-6829, 2016 (2016)
Theoretical and experimental investigations on molecular structure of 7-Chloro-9-phenyl-2,3-dihydroacridin-4(1H)-one with cytotoxic studies R. Satheeshkumar, R. Shankar; W. Kaminsky, S. Kalaiselvi; V. Vijaya Padma, K. J. Rajendra Prasad Article Journal of Molecular Structure, 1109, 247-257, 2016. (2016)
Efficient Protocol for Synthesis of Pyrazolo[3,4-a]acridines R. Satheeshkumar, W. Kaminsky; H. A. Sparkes, K. J. Rajendra Prasad Article Synthetic Communications, 45, 2203-2215, 2015 (2015)
Quinoline alkaloids – Synthesis, molecular docking studies of atanine, 2-isopropylfuro [2,3-b] quinolines and 3,4-dihydro-2,2-dimethyl-2H-pyrano [2,3-b]quinolines R. Satheeshkumar, C. Kavitha; A. Muthusankar, P. Shanmughavel Article Indian Journal of Chemistry Section B, 54B(8), 988-998, 2015 (2015)
A facile regioselective 1,3-dipolar cycloaddition protocol for the synthesis of new class of quinolinyl dispiro heterocycles G. Senthil Kumar, R. Satheeshkumar; W. Kaminsky, J. Platts Article Tetrahedron Lett. 55, 5475-5480, 2014 (2014)

Rajendran Satheeshkumar

Postdoctoral Fellow

Organic Chemistry

Pontificia Universidad Católica de Chile

Pontificia Universidad Católica de Chile, Santiago, Chile, Chile

Ariesny Vera

Flavia Zacconi

Associate Professor

Organic Chemistry

Pontificia Universidad Católica de Chile

Santiago, Chile

Rajendran Satheeshkumar

Líneas de Investigación

Educación

Organic Chemistry, Bharathiar University. India, 2017

Article (18)

Experimental and theoretical physicochemical study of a new dispirocompound: 4 '-(4-fluorophenyl)-2 ',7-dimethyl-1,4-dihydro-3H-dispiro[cyclopent[b]indol-2,5 '-[1,2]oxazinan-6 ' 3 ''-indolin]-2 '',3-dione

Small interfering RNA for cancer treatment: overcoming hurdles in delivery

Synthesis of Novel Quin[1,2-b]Acridines: In Vitro Cytotoxicity and Molecular Docking Studies

An expedient synthesis of isoxazolo - and pyrazolo-[3,4-a]acridines with molecular docking studies

Synthesis of heteroannulated cyclopent[b]indoles=> Exploration of in vitro cytotoxicity and molecular docking studies

Synthesis, spectroscopic, in vitro cytotoxicity and crystal structures of novel fluorinated dispiroheterocycles=> DFT approach

A Facile Regioselective Synthesis of New Class of Cyclopent[b]indole dispiro heterocycles via1,3‐Dipolar Cycloaddition protocol and in vitro Cytotoxic studies

Efficient novel synthesis of pyrano[3,2-a]- and pyrazolo[4,3-a]-acridines

Indium triflate and ionic liquid-mediated Friedländer synthesis of 2-acylquinolines

Solvent-free synthesis of dibenzo[b,j][1,10]phenanthroline derivatives using Eaton’s reagent as catalyst

Synthesis, spectral analysis and quantum chemical studies on molecular geometry, chemical reactivity of 7-chloro-9-(2′-chlorophenyl)-2,3-dihydroacridin-4(1H)-one and 7-chloro-9-(2′-fluorophenyl)-2,3-dihydroacridin-4(1H)-one

DABCO prompted tandem and multicomponent synthetic protocol of pyrano[2,3-a]acridines

Novel Synthetic and Mechanistic Approach of TFA Catalysed Friedländer Synthesis of 2‐Acylquinolines from Symmetrical and Unsymmetrical 1,2‐Diketones with o‐Aminoarylketones

Theoretical and experimental investigations on molecular structure of 7-Chloro-9-phenyl-2,3-dihydroacridin-4(1H)-one with cytotoxic studies

Efficient Protocol for Synthesis of Pyrazolo[3,4-a]acridines

Quinoline alkaloids – Synthesis, molecular docking studies of atanine, 2-isopropylfuro [2,3-b] quinolines and 3,4-dihydro-2,2-dimethyl-2H-pyrano [2,3-b]quinolines

A facile regioselective 1,3-dipolar cycloaddition protocol for the synthesis of new class of quinolinyl dispiro heterocycles

Rajendran Satheeshkumar

Ariesny Vera

Flavia Zacconi