Daniel Jordi Hachim Diaz
Assistant Professor
Pontificia Universidad Católica de Chile
Santiago, Chile
- Functional Biomaterials - Drug delivery - Tissue engineering - Organ-on-a-chip
-
Tissue Engineering and Regenerative Medicine, UNIVERSITY OF PITTSBURGH. Estados Unidos, 2017
-
Pharmaceutical Sciences, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2010
-
Assistant Professor Full Time
PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE
Química y de Farmacia
Chile
2023 - A la fecha
-
Postdoctoral Research Associate Full Time
IMPERIAL COLLEGE LONDON
Engineering
London, Reino Unido
2018 - 2022
-
PhD Student Full Time
University of Pittsburgh
Estados Unidos
2012 - 2017
-
Investigador Asistente Part Time
PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE
Química y de Farmacia
Chile
2010 - 2012
-
Profesor Instructor Part Time
PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE
Química y de Farmacia
Chile
2010 - 2012
-
Assistant Professor Full Time
Pontificia Universidad Catolica de Chile
Santiago, Chile
2023 - A la fecha
-
Research Assistant Part Time
Pontificia Universidad Catolica de Chile
Chile
2010 - 2012
-
Instructor Professor Part Time
Pontificia Universidad Catolica de Chile
Chile
2010 - 2011
- Pontificia Universidad Católica de Chile: I am Director of three undergraduate thesis and co-director of three PhD. Students.
- Imperial College London: I have mentored and co-supervised the Theses of seven graduated Master Students and 2 PhD students (not graduated yet)
- McGowan Institute for Regenerative Medicine. I have mentored six students and one Visiting Scholar in laboratory skills and research study design. Two of my students have won awards (Best Poster in undergraduate category) for the research done under my supervision.
Patents and Disclosures:
1. Hachim D, Brown BN. Layer by Layer Coated Mesh for Local Release of Bio-active Proteins. US20170266352A1. (2016).
2. Hachim D, Ebensperger R. Method for selective targeting of nanoencapsulated cells on target tissue or organs. WO2013106944 A3. (2013).
3. Hachim D, Ghurman H, Modo M, Brown BN. Labeling Methods of Extracellular Matrix- Derived Scaffolds for Research and Clinical Monitoring. Invention disclosure in progress. Pitt Ref 04308. (2017).
Conferences:
1. Hachim D*, Foote J, Herna?ndez O, Delahaye M, Ouyang L, Wang R, Harding SE, Stevens MM. Glycosaminoglycan-PEDOT conductive hydrogels for iPSC-derived cardiomyocyte implantation and electrical coupling. 7th International Bioelectronics Conference 2022. Tirol, Austria.
2. Hachim D*, Zhao J, Bhankaria J, Nun?ez-Toldra R, Brito L, Seong H, Becce M, Grigsby C, Terracciano C, Stevens MM. Polysaccharide-polyplex ultrathin coatings for nanoneedle-based gene delivery. Tissue Engineering and Regenerative Medicine International Society (TERMIS) - World Conference 2021 (Podium presentation). Maastricht, Netherlands.
3. Hachim D*, Mylonaki I, Dondi C, Stuckey D, Brito L, Harding SE, Stevens MM. Injectable memory-shape cryogels for minimally invasive delivery of cardiac progenitors into the heart. 11th World Biomaterials Congress (Podium presentation). December 2020. Glasgow, Scotland, United Kingdom.
4. Hachim D, Mylonaki I*, Dondi C, Stuckey D, Brito L, Harding SE, Stevens MM. An injectable shape-memory cell-laden hydrogel patch for cell delivery on the heart. Cardiovascular Biology and Vascular Tissue Engineering Conference. June 2019. Zurich, Switzerland.
5. Hachim D*, LoPresti ST, Brown BN. Unveiling macrophage populations and mechanisms driving the better remodeling outcomes associated with shifting phenotype in the host response against biomaterials (Podium and poster presentation). Regenerative Medicine Workshop, March 2017. Hilton Head Island, SC, United States.
6. Hachim D*, LoPresti ST, Brown BN. IL-4 Eluting Nano-layered Coating Promotes Better Implant Integration into the Host Tissue via Macrophage Modulation (Podium presentation). Tissue Engineering and Regenerative Medicine Society (TERMIS) 2016, December 2016. San Diego, CA, United States.
7. Hachim D*, LoPresti ST, Mani D, Brown BN. Improvements in the resolution of the foreign body reaction by the modulation of macrophage polarization towards an M2 phenotype at the tissue-implant interface by local release of IL-4 from layer by layer coated polypropylene meshes (Podium presentation). Front. Bioeng. Biotechnol. Conference Abstract: 10th World Biomaterials Congress, May 2016. Montreal, Canada.
8. Hachim D, Mani D, LoPresti ST, Brown BN*. Effects of Aging upon the Host Response to Polypropylene Mesh (Podium presentation). AUGS 36th Annual Meeting, October 2016. Seattle, WA, United States.
9. Hachim D, Mani D, LoPresti ST, Brown BN*. Promoting Tissue Integration via Release of IL-4 from the Surface of Polypropylene Mesh (Podium presentation). AUGS 36th Annual Meeting, October 2016. Seattle, WA, United States.
10.Hachim D*, LoPresti ST, Mani D, Brown BN. Modulation of Macrophage Polarization at the Tissue-Implant Interface by Local Release of IL-4 from a Nanometer Thickness Coating on Polypropylene Meshes. Biomedical Engineering Society (Podium presentation), October 2015. Tampa, FL, United States.
11.Hachim D*, LoPresti ST, Mani D, Brown BN. Modulation of Macrophage Polarization at the Tissue Implant Interface by Local Release of IL-4 from a Nanometer Thickness Coating on Polypropylene Meshes. Regenerative Medicine Workshop (Poster), May 2015. Hilton Head, NC, United States.
12.Hachim D*, LoPresti ST, Mani D, Brown BN. Pro-remodeling Macrophage Polarization at the Tissue-Implant Interface by Local Release of IL-4 from Coated Polypropylene Meshes. TERMIS Word Conference (Poster), September 2015. Boston, MA, United States.
13. Hachim D*, LoPresti ST, Brown BN. Development of a Cytokine-Loaded Layer by Layer Coating on Polypropylene Meshes to Modulate Macrophage Polarization at the Tissue-Implant Interface. Society for Biomaterials (Podium presentation), April 2015. Charlotte, NC, United States.
14. Hachim D*, Ebensperger R. Polycation influence on cell viability in nanoencapsulation of human adipose derived mesenchymal stem cells (Poster presentation). XXIV Annual congress of the Chilean Society of Cell Biology, November 2010. Puco?n, Chile.
Organization of Events at International Conferences:
- Exploring options after your degree. Panel discussion at the Society for Biomaterials Conference, April 2018, Atlanta. Role: Session organizer.
Leadership and Outreach:
- 2022. Stevens Group exhibition committee. Great Exhibition Road Festival, London, United Kingdom.
- 2018, 2019. Volunteer exhibitor. London International Young Science Forum (LIYSF).
- 2017 - 2018. President, Society for Biomaterials (SFB) United States National Student Council.
- 2016 - 2017. President-elect, Society for Biomaterials (SFB) United States National Student Council.
- 2015 - 2018. Student Representative and Webmaster, Society for Biomaterials, Drug Delivery SIG.
- 2015 - 2017. Newsletter Chair, Biomedical Engineering Society Chapter (BMES), University of Pittsburgh.
-
3rd Place for Best Poster Presentation
Congreso Ingeniería en Tejidos y Medicina Regenerativa 2024
Chile, 2024
3rd Place for Best Poster Presentation
-
1st Prize Award for Best Poster Presentation
IMPERIAL COLLEGE LONDON
Reino Unido, 2018
1st Prize Award for Best Poster Presentation at the 8th Annual Department of Materials Postdoc Symposium 2018, Imperial College, London, UK.
-
Seal of Excellence
EUROPEAN UNION
Chile, 2018
Horizon 2020’s Marie Sklodowska - Curie Actions. Seal of Excellence for proposal “Conformally coated nanoneedles (CoNad) for sustained and sequential drug delivery for cardiac ischaemia-reperfusion injury”.
-
2nd place in 2016 TERMIS-AM Business Competition
TERMIS
Estados Unidos, 2017
2nd place in 2016 TERMIS-AM Business Competition, December 11th - 14th, San Diego, CA.
-
2nd place in the Wells Healthcare Business Competition
UNIVERSITY OF PITTSBURGH
Chile, 2016
2nd place in the Wells Healthcare Business Competition (US$ 10,000), Pittsburgh, PA.
-
NSF I-Corps Program Award
UNIVERSITY OF PITTSBURGH
Chile, 2016
NSF I-Corps Program Award (US$3,000) for “Layer-Up”. University of Pittsburgh, PA.
-
Finalist. Round-1 Pilot Funding Program
UNIVERSITY OF PITTSBURGH
Chile, 2016
Finalist. Round-1 Pilot Funding Program, Pittsburgh's Center for Medical Innovation (CMI).
-
Fulbright Fellowship
COMISION FULBRIGHT-CHILE
Chile, 2012
Fulbright Fellowship for Doctoral Studies
Daniel Hachim
Assistant Professor
Química y de Farmacia
Pontificia Universidad Católica de Chile
Santiago, Chile