Man

Marina Gaínza Lein

Académico Investigador

Universidad Austral de Chile

Valdivia, Chile

Líneas de Investigación


Pediatric neurologist specialized in Lifestyle Medicine. I research how lifestyle habits interact with the gut microbiota and how this, in turn, influences the brain in children. I also continue my previous line of research in pediatric epilepsy.

Educación

  •  Neuróloga Infantil, UNIVERSIDAD DE CHILE. Chile, 2024
  •  Lifestyle Medicine Physician, International Board of Lifestyle Medicine. Estados Unidos, 2020
  •  Médico Cirujano, UNIVERSIDAD AUSTRAL DE CHILE. Chile, 2018
  •   Applied Biostatistics , HARVARD UNIVERSITY. Estados Unidos, 2016
  •  Research Fellowship, HARVARD UNIVERSITY. Chile, 2017

Experiencia Académica

  •   Académico Investigador Part Time

    UNIVERSIDAD AUSTRAL DE CHILE

    Medicina

    Valdivia, Chile

    2019 - A la fecha

  •   Docente Diplomado Estilos de Vida Saludable Other

    UNIVERSIDAD DE LOS ANDES

    Chile

    2021 - A la fecha

  •   Directora Diplomado en Medicina del Estilo de Vida Infantil Part Time

    Sembrando Salud

    Valdivia, Chile

    2021 - A la fecha

  •   Vice Directora Sociedad Chilena de Medicina y Nutrición Preventiva Part Time

    SOCHIMENUP

    Chile

    2021 - 2024

  •   Comite Investigacion Part Time

    Sociedad Chilena de Medicina del Estilo de Vida

    Chile

    2023 - A la fecha

Experiencia Profesional

  •   Neuróloga Infantil Part Time

    Clinica Alemana Valdivia

    Chile

    2023 - A la fecha


 

Article (36)

Assessment of Seizure Action Plans in Pediatric Convulsive Status Epilepticus: Focus on Benzodiazepine-Responsive and Resistant Cases

Stredny, Coral M.; Rostamian, Sahar; Sheehan, Theodore Alexander; Gainza-Lein, Marina; Carey, Shannon; Lewis, Samuel; Clark, Justice; Bucciarelli, Bethany; Chiujdea, Madeline; Antonetty, Annalee; et al.

Article ISI
NEUROLOGY-CLINICAL PRACTICE  (2025)

Evolution in the prescription and cost of non-intravenous rescue benzodiazepines for the treatment of seizure emergencies

Fernandez, Ivan Sanchez; Amengual-Gual, Marta; Aguilar, Cristina Barcia; Khan, Taha Fathima; Gainza-Lein, Marina; Torres, Alcy; Rinat, Jonas; Douglass, Laurie

Article ISI
EPILEPSIA  (2025)

Foundations of Pediatric Lifestyle Medicine



Article ISI
CHILDREN-BASEL  (2025)

Early Clinical Variables Associated With Refractory Convulsive Status Epilepticus in Children

Peariso, Katrina; Arya, Ravindra S.; Glauser, Tracy; Abend, Nicholas; Aguilar, Cristina Barcia; Amengual-Gual, Marta L.; Anderson, Anne; Appavu, Brian; Brenton, J. Nicholas E.; Carpenter, Jessica; et al.

Article ISI
NEUROLOGY  (2023)

Evolution of antiseizure medication use and cost in the United States of America 2006-2021

Fernandez, Ivan Sanchez; Gainza-Lein, Marina; Amengual-Gual, Marta; Aguilar, Cristina Barcia; Romeu, Amanda; Torres, Alcy; Jonas, Rinat; Douglass, Laurie M.

Article ISI
SEIZURE-EUROPEAN JOURNAL OF EPILEPSY  (2023)

Health care resource utilization and costs before and after epilepsy surgery

Fernandez, Ivan Sanchez; Amengual-Gual, Marta; Aguilar, Cristina Barcia; Romeu, Amanda; Jonas, Rinat; Torres, Alcy; Gainza-Lein, Marina; Douglass, Laurie

Article ISI
SEIZURE-EUROPEAN JOURNAL OF EPILEPSY  (2023)

Temporal trends in the cost and use of first-line treatments for infantile epileptic spasms syndrome

Fernandez, Ivan Sanchez; Amengual-Gual, Marta; Aguilar, Cristina Barcia; Romeu, Amanda; Sheikh, Tahir; Torres, Alcy; Chao, Jessica; Jonas, Rinat; Gainza-Lein, Marina; Harini, Chellamani; et al.

Article ISI
EPILEPSIA  (2023)

Prevalence and Predictors of Seizure Clusters in Pediatric Patients With Epilepsy: The Harvard-Yale Pediatric Seizure Cluster Study

Jafarpour, Saba; Fong, Michael W. K.; Detyniecki, Kamil; Khan, Ambar; Jackson-Shaheed, Ebony; Wang, Xiaofan; Lewis, Samuel; Benjamin, Robert; Gainza-Lein, Marina; O'Bryan, Jane; et al.

Article ISI
PEDIATRIC NEUROLOGY  (2022)

Benzodiazepine administration patterns before escalation to second-line medications in pediatric refractory convulsive status epilepticus

Sheehan, Theodore; Amengual-Gual, Marta; Vasquez, Alejandra; Abend, Nicholas S.; Anderson, Anne; Appavu, Brian; Arya, Ravindra; Aguilar, Cristina Barcia; Brenton, J. Nicholas; Carpenter, Jessica L.; et al.

Article ISI
EPILEPSIA  (2021)

Clinical presentation of new onset refractory status epilepticus in children (the pSERG cohort)

Sculier, Claudine; Barcia Aguilar, Cristina; Gaspard, Nicolas; Gainza-Lein, Marina; Sanchez Fernandez, Ivan; Amengual-Gual, Marta; Anderson, Anne; Arya, Ravindra; Burrows, Brian T.; Brenton, James N.; et al.

Article ISI
EPILEPSIA  (2021)

Cost-effectiveness of adrenocorticotropic hormone versus oral steroids for infantile spasms

Sanchez Fernandez, Ivan; Amengual-Gual, Marta; Gainza-Lein, Marina; Barcia Aguilar, Cristina; Bergin, Ann Marie; Yuskaitis, Christopher J.; Harini, Chellamani

Article ISI
EPILEPSIA  (2021)

Descriptive epidemiology and health resource utilization for status epilepticus in the emergency department in the United States of America

Fernandez, Ivan Sanchez; Amengual-Gual, Marta; Barcia Aguilar, Cristina; Gainza-Lein, Marina

Article ISI
SEIZURE-EUROPEAN JOURNAL OF EPILEPSY  (2021)

Factors associated with long-term outcomes in pediatric refractory status epilepticus

Gainza-Lein, Marina; Barcia Aguilar, Cristina; Piantino, Juan; Chapman, Kevin E.; Sanchez Fernandez, Ivan; Amengual-Gual, Marta; Anderson, Anne; Appavu, Brian; Arya, Ravindra; Brenton, James Nicholas; et al.

Article ISI
EPILEPSIA  (2021)

Time to Treatment in Pediatric Convulsive Refractory Status Epilepticus: The Weekend Effect

Aguilar, Cristina Barcia; Amengual-Gual, Marta; Fernandez, Ivan Sanchez; Abend, Nicholas S.; Anderson, Anne; Appavu, Brian; Arya, Ravindra; Brenton, J. Nicholas; Carpenter, Jessica L.; Chapman, Kevin E.; et al.

Article ISI
PEDIATRIC NEUROLOGY  (2021)

Association of guideline publication and delays to treatment in pediatric status epilepticus

Sanchez Fernandez, Ivan; Abend, Nicholas S.; Amengual-Gual, Marta; Anderson, Anne; Arya, Ravindra; Barcia Aguilar, Cristina; Brenton, James Nicholas; Carpenter, Jessica L.; Chapman, Kevin E.; Clark, Justice; et al.

Article ISI
NEUROLOGY  (2020)

Congenital anomalies and comorbidities in neonates with Down Syndrome

Nakousi Capurro, Nicole; Cares Basualto, Carolina; Alegria Olivos, Angelica; Gainza Lein, Marina; Lopez Aristizabal, Luis; Gayan Torrente, Alejandro; Ojeda Contreras, Valentina; Irarrazaval Montero, Maria Jose

Article ISI
REVISTA CHILENA DE PEDIATRIA  (2020)

First-line medication dosing in pediatric refractory status epilepticus

Vasquez, Alejandra; Gainza-Lein, Marina; Abend, Nicholas S.; Amengual-Gual, Marta; Anderson, Anne; Arya, Ravindra; Brenton, J. Nicholas; Carpenter, Jessica L.; Chapman, Kevin; Clark, Justice; et al.

Article ISI
NEUROLOGY  (2020)

The burden of decisional uncertainty in the treatment of status epilepticus

Sanchez Fernandez, Ivan; Gainza-Lein, Marina; Barcia Aguilar, Cristina; Amengual-Gual, Marta; Loddenkemper, Tobias

Article ISI
EPILEPSIA  (2020)

Diagnostic yield of genetic tests in epilepsy: A meta-analysis and cost-effectiveness study

Sheidley, BR; Poduri, A.

Article ISI SCOPUS
NEUROLOGY  (2019)

Electroencephalographic Reporting for Refractory Status Epilepticus

Carpenter J.L.; Williams K.L.; Pediatric Status Epilepticus Research Group (pSERG)

Article ISI SCOPUS
JOURNAL OF CLINICAL NEUROPHYSIOLOGY  (2019)

Meta-analysis and cost-effectiveness of second-line antiepileptic drugs for status epilepticus

Lamb N.

Article ISI SCOPUS
NEUROLOGY  (2019)

Severe acute respiratory infections (SARI) from influenza in adult patients in Chile: the experience of a sentinel hospital

Fasce, R.; Triantafilo V.; El Omeiri N.

Article ISI SCOPUS
REVISTA PANAMERICANA DE SALUD PUBLICA-PAN AMERICAN JOURNAL OF PUBLIC HEALTH  (2019)

The onset of pediatric refractory status epilepticus is not distributed uniformly during the day

Amengual-Gual M.; Carpenter J.L.; Farias-Moeller R.; Davis Gaillard W.; Guerriero R.M.; Hecox K.; Kossoff E.H.W.; Morgan L.A.; Novotny E.J.; Payne E.T.; et al.

Article ISI SCOPUS
SEIZURE-EUROPEAN JOURNAL OF EPILEPSY  (2019)

Association of Time to Treatment With Short-term Outcomes for Pediatric Patients With Refractory Convulsive Status Epilepticus

Jackson M.; Williams K.; Loddenkemper T.

Article ISI SCOPUS
JAMA NEUROLOGY  (2018)

Different as night and day: Patterns of isolated seizures, clusters, and status epilepticus

Goldenholz, DM; Rakesh, K; Hodgeman, R; Moss, R; Theodore, WH; Loddenkemper T.

Article ISI SCOPUS
EPILEPSIA  (2018)

Efficacy and safety of ketogenic diet for treatment of pediatric convulsive refractory status epilepticus

Harvey J.; Bergin, A; Burrows, BT; Lai, YC; Wilfong, AA; Williams K.; Loddenkemper T.

Article ISI SCOPUS
EPILEPSY RESEARCH  (2018)

Factors associated with treatment delays in pediatric refractory convulsive status epilepticus

Clark J.; Helseth, AR; Nayak A.; Riviello, JJ; Williams K.; Loddenkemper T.

Article ISI SCOPUS
NEUROLOGY  (2018)

Hospital Emergency Treatment of Convulsive Status Epilepticus: Comparison of Pathways From Ten Pediatric Research Centers

Carpenter J.L.; Chapman K.; Clark J.; Goldstein J.; Nayak A.; Payne E.; Pediatric Status Epilepticus Research Group (pSERG)

Article ISI SCOPUS
Pediatric Neurology  (2018)

Long-term outcomes of status epilepticus: A critical assessment

Sculier, C; Loddenkemper T.

Article ISI SCOPUS
EPILEPSIA  (2018)

Machine Learning for Outcome Prediction in Electroencephalograph (EEG)-Monitored Children in the Intensive Care Unit

Loddenkemper T.

Article ISI SCOPUS
JOURNAL OF CHILD NEUROLOGY  (2018)

Time to continuous electroencephalogram in repeated admissions to the pediatric intensive care unit

Sansevere, AJ; Buraniqi, E; Loddenkemper T.

Article ISI SCOPUS
SEIZURE-EUROPEAN JOURNAL OF EPILEPSY  (2018)

Nonintravenous rescue medications for pediatric status epilepticus: A cost-effectiveness analysis

Sánchez Fernández I.; gaínza-lein M.

Article ISI SCOPUS
EPILEPSIA  (2017)

Novel clinical manifestations in patients with KCNA2 mutations

Sachdev, M; Tchapyjnikov, D; Jiang, YH

Article ISI SCOPUS
Seizure  (2017)

Refractory status epilepticus in children with and without prior epilepsy or status epilepticus

Fernández I.S.; Jackson M.C.; Abend N.S.; Arya R.; Brenton J.N.; Chapman K.E.; Gaillard W.D.; gaínza-lein M.; Glauser T.A.; Goldstein J.L.; et al.

Article ISI SCOPUS
NEUROLOGY  (2017)

Rescue Medications in Epilepsy Patients: A Family Perspective

Stredny, C; McGurl, M

Article ISI SCOPUS
Seizure  (2017)

Use of EEG in critically ill children and neonates in the United States of America

gaínza-lein M.; Sánchez Fernández I.

Article ISI SCOPUS
JOURNAL OF NEUROLOGY  (2017)

BookSection (1)

Medicina del Estilo de Vida Infantil: una propuesta ante nuevos desafíos en salud pediátrica

Marina Gaínza Lein; Lidia B. Giúdici

BookSection
 (2024)

Review (4)

Seizure cluster: Definition, prevalence, consequences, and management



Review ISI
SEIZURE-EUROPEAN JOURNAL OF EPILEPSY  (2019)

Timing in the treatment of status epilepticus: From basics to the clinic



Review ISI
SEIZURE-EUROPEAN JOURNAL OF EPILEPSY  (2019)

HHV-6 and seizure: A systematic review and meta-analysis

Mohammadpour Touserkani F.; gaínza-lein M.; Jafarpour S.; Brinegar K.; Kapur K.

Review ISI SCOPUS
JOURNAL OF MEDICAL VIROLOGY  (2017)

Automated seizure detection systems and their effectiveness for each type of seizure

Ulate-Campos, A; Coughlin, F; Pearl, PL

Review ISI SCOPUS
SEIZURE-EUROPEAN JOURNAL OF EPILEPSY  (2016)

1
Rodrigo Fasce

Jefe Subdepto. Enfermedades Virales

Biomédico

Instituto de Salud Pública

Santiago, Chile

1
Alberto Fica

Médico Infectólogo

Medicina

Hospital Base de Valdivia

Valdivia, Chile

1
Nicole Nakousi

Genetista Clínico

Pediatría

Hospital Carlos Van Buren

Valparaíso, Chile

1
ANDRES SOTO

Médico Infectólogo, Hospital del Salvador. Profesor Asistente, Facultad de Medicina, Universidad de Chile.

Medicina Interna Oriente

Universidad de Chile/Hospital del Salvador

Santiago, Chile

41
Marina Gaínza

Académico Investigador

Pediatría

Universidad Austral de Chile

Valdivia, Chile