Man

Francisco Javier Morera Galleguillos

Assistant Professor

Pontificia Universidad Católica de Chile

Santiago, Chile

Líneas de Investigación


1) Molecular markers of smoltification in Atlantic salmon 2) Salmon physiology and biotechnology 3) Biotechnological applications in veterinary sciences

Educación

  •  Cellular and Molecular Biology, UNIVERSIDAD AUSTRAL DE CHILE. Chile, 2008

Experiencia Académica

  •   Assistant Professor Full Time

    UNIVERSIDAD AUSTRAL DE CHILE

    Veterinary Sciences

    Valdivia, Chile

    2011 - 2016

  •   Associate Professor Full Time

    UNIVERSIDAD AUSTRAL DE CHILE

    Veterinary Sciences

    Valdivia, Chile

    2016 - 2023

  •   Assistant Professor Full Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Facultad de Medicina

    Santiago, Chile

    2023 - At present

Experiencia Profesional

  •   Postdoctoral Researcher Full Time

    University of California, Los Angeles

    Los Angeles, Estados Unidos

    2009 - 2011

  •   Postdoctoral Researcher Full Time

    Centro de Neurociencia de Valparaiso

    Valparaiso, Chile

    2008 - 2009

Formación de Capital Humano


Carlos Loncoman Pardo (2013) Expresion del canal de K+ activado por calcio de alta conductancia (BK) en tejids de trucha arcoiris O. mykiss y salmon del atlantico salmo salar. Undergraduate Thesis Direction, Universidad Austral de Chile.

MARCELO IVÁN SALDIVIA BARRÍA (2014) Construcción de un plásmido lentiviral para el marcaje de células madre embrionarias de ratón mediante la expresión del gen reportero que codifica para la proteina fluorescente roja. Undergraduate Thesis Direction, Universidad Austral de Chile.

ANÍBAL ALFONSO ARAVENA GARCÍA and CARLOS EDUARDO ARAYA SALDÍAS (2014) La pertinencia de la enseñanza de la farmacología dentro de la formación profesional del profesor de educación física, deportes y recreación de la Universidad Austral de Chile. Undergraduate Thesis Direction, Universidad Austral de Chile.

Litto Gutierrez (2014) Memoria de Titulo Tecnologia Medica, Universidad Austral de Chile.

ROMINA YASMINE WALKER VERGARA (2015) Detección Molecular de Mycoplasmas Hemotrópicos en Felinos domésticos de sur de Chile. Master thesis co-Direction, Universidad Austral de Chile.

Antonia Virginia Francisco Pedro (2017) Variacion de la expresion genica en la respuesta oxidativa hepatica y muscular de Salmo salarbante infeccion por P. salmonis" Master thesis Direction, Universidad Austral de Chile.

Atenea Servat (2019) "Modulación de la citotoxicidad dopaminérgica por esteroides sexuales: Revisión bibliográfica". Memoria de titulo de Medicina Veterinaria, Universidad Austral de Chile.

Rodrigo Andrés Moran Figueroa (2021) Análisis de cambios de expresión transcripcional durante la Smoltificación del salmón del Atlántico (Salmo salar) mediante herramientas bioinformáticas. Memoria de Titulo Bioquímico, Universidad de Chile.

Jorge Rodrigo Chavez Oyarzun (2023) Caracterización del efecto del tiempo de cultivo y de la estacionalidad sobre la expresión de las subunidades ?1a y ?1b de la Na + , K + -ATPasa (NKA) en cultivo de explantes branquiales de Trucha Arcoíris (Oncorhynchus mykiss). Tesis de Grado para el titulo de Biólogo Marino. Universidad Austral de Chile.

Cristóbal Jiménez (2023) “Monitoreo de la expresión diferencial de posibles nuevos marcadores en la esmoltificación de Salmo salar”. Tesis de Grado para el titulo de Biólogo Marino. Universidad Austral de Chile

Diego Sebastián Garrido Stancic (2024) “REVISIÓN BIBLIOGRÁFICA: BASES BIOLÓGICAS DE LA ESMOLTIFICACIÓN DEL SALMÓN DEL ATLÁNTICO Y EFECTOS DE SUS PRINCIPALES MANEJOS PRODUCTIVOS”. Memoria de titulo de Medicina Veterinaria, Universidad Austral de Chile.


Difusión y Transferencia


Participación como Evaluador en el XV Congreso Escolar de Ciencia y Tecnología Explora de CONICYT- Los Ríos, realizada en el Centro de Ferias del Parque Saval los días 26, 27 y 28 de septiembre de 2018.

Asesor Científico del Proyecto de Club de Ciencias Seleccionado por Explora Los Rios 2014 cuyas actividades se realizaron desde Marzo 205 hasta septiembre 2015:
“Club de ciencias Mawenko – agua de lluvia” (Colegio Nuestra Señora del Carmen de Valdivia)

Participación en PROGRAMA “ABRAMOS NUESTROS LABORATORIOS A LA INVESTIGACIÓN CIENTÍFICA ESCOLAR 2014” (primer semestre).

Presentación de resultados en XI CONGRESO REGIONAL ESCOLAR DE CIENCIA y TECNOLOGÍA EXPLORA CONICYT:
Villa, Y., Carrillo, C.1; Vargas, J.1 ; Leal, P1; Vásquez, M.1; Manosalva, C..3 y Morera F.J.2 (2014) “Efecto de productos derivados del maqui sobre la cicatrización en un modelo celular” 1Colegio Nuestra Señora del Carmen Valdivia; 2Facultad de Ciencias Veterinarias y 3 Facultad de Ciencias, Universidad Austral de Chile;



 

Article (51)

Interleukin 3 Inhibits Glutamate-Cytotoxicity in Neuroblastoma Cell Line
<i>Piscine</i><i> orthoreovirus</i> 3a detected from farmed coho salmon with jaundice syndrome displays positive selection and polymorphisms in S1 and M2 viral segment
Discovery of BbX transcription factor in the patagonian blennie: Exploring expression changes following combined bacterial and thermal stress exposure
How Many Sirtuin Genes Are Out There? Evolution of Sirtuin Genes in Vertebrates With a Description of a New Family Member
Revealing the <i>Salmo salar</i> NLRP3 Inflammasome: Insights from Structural Modeling and Transcriptome Analysis
Identification of multiple TAR DNA binding protein retropseudogene lineages during the evolution of primates
Immune response of Salmo salar (exotic fish) and Eleginops maclovinus (native fish) during Francisella noatunensis horizontal transference
Metabolic changes induced by DNA damage in Ramos cells: exploring the role of mTORC1 complex
Dynamics of BK channel expression in gills during smoltification of Atlantic Salmon under farm conditions
Independent duplications of the Golgi phosphoprotein 3 oncogene in birds
Piscirickettsia salmonis-Triggered Extracellular Traps Formation as an Innate Immune Response of Atlantic Salmon-Derived Polymorphonuclear Neutrophils
The biological basis of smoltification in Atlantic salmon
Francisella noatunensis subsp. noatunensis triggers calcium metabolism gene modulation in Eleginops maclovinus
Intermediary metabolic response and gene transcription modulation on the Sub-Antarctic notothenioid Eleginops maclovinus (Valenciennes, 1930) injected with two strains of Piscirickettsia salmonis
Molecular Detection ofGurltia paralysansby Semi-Nested PCR in Cerebrospinal Fluid and Serum Samples from Domestic Cats (Felis catus)
Stocking density affects the growth performance, intermediary metabolism, osmoregulation, and response to stress in Patagonian blennie Eleginops maclovinus
Vincristine, carboplatin and cisplatin increase oxidative burst induced by PAF in canine neutrophils
Early differential gene expression in beef Longissimus thoracis muscles from carcasses with normal (< 5.8) and high (> 5.9) ultimate pH
Modulation of the Expression of Immune-related Gene in Atlantic and Coho Salmon during Infestation with the Sea lice Caligus rogercresseyi
Neuroendocrine stress response in Atlantic salmon (Salmo salar) and Coho salmon (Oncorynchus kisutch) during sea lice infestation
The expression pattern of calcium signaling-related genes during smoltification of Salmo salar in productive conditions
Transcriptional activation of genes involved in oxidative stress in Salmo salar challenged with Piscirickettsia salmonis
BK potassium channel mRNA level changes in gills of Atlantic salmon after brackish water transfer
Effects of acclimation to high environmental temperatures on intermediary metabolism and osmoregulation in the sub-Antarctic notothenioid Eleginops maclovinus
Intestinal incomplete process on the osmoregulation system during Salmo salar smoltification in a productive conditions
Delphinidin Reduces Glucose Uptake in Mice Jejunal Tissue and Human Intestinal Cells Lines through FFA1/GPR40
Ectoparasite Caligus rogercresseyi modifies the lactate response in Atlantic salmon (Salmo salar) and Coho salmon (Oncorhynchus kisutch)
Ectoparasite Caligus rogercresseyi modifies the lactate response in Atlantic salmon (Salmo salar) and Coho salmon (Oncorhynchus kisutch)
Natural recombination in alphaherpesviruses=> Insights into viral evolution through full genome sequencing and sequence analysis
Atlantic salmon (Salmo salar) and Coho salmon (Oncorhynchus kisutch) display differential metabolic changes in response to infestation by the ectoparasite Caligus rogercresseyi
Atlantic salmon (Salmo salar) and Coho salmon (Oncorhynchus kisutch) display differential metabolic changes in response to infestation by the ectoparasite Caligus rogercresseyi
Identification and expressional analysis of NLRC5 inflammasome gene in smolting Atlantic salmon (Salmo salar)
Prevalence, risk factor analysis, and hematological findings of hemoplasma infection in domestic cats from Valdivia, Southern Chile
Application of a real- time PCR assay to detect BK potassium channels expression in samples from Atlantic salmon (Salmo salar) and Rainbow trout (Oncorhynchus mykiss) acclimated to freshwater.
Application of a real-time PCR assay to detect BK potassium channel expression in samples from Atlantic salmon (Salmo salar) and Rainbow trout (Oncorhynchus mykiss) acclimated to freshwater
VOLTAGE-DEPENDENT BK AND Hv1 CHANNELS EXPRESSED IN NON-EXCITABLE TISSUES: NEW THERAPEUTICS OPPORTUNITIES AS TARGETS IN HUMAN DISEASES
Voltage-dependent BK and Hv1 channels expressed in non-excitable tissues: New therapeutics opportunities as targets in human diseases
Voltage-gated proton (H(v)1) channels, a singular voltage sensing domain
Voltage-Gated Proton (Hv1) Channels, a Singular Voltage Sensing Domain
The first transmembrane domain (TM1) of beta 2-subunit binds to the transmembrane domain S1 of alpha-subunit in BK potassium channels
The first transmembrane domain (TM1) of beta2-subunit binds to the transmembrane domain S1 of alpha-subunit in BK potassium channels
Allosteric interactions and the modular nature of the voltage- and Ca2+-activated (BK) channel
Allosteric interactions and the modular nature of the voltage- and Ca2+-activated (BK) channel
Cell volume and membrane stretch independently control K+ channel activity
Cell volume and membrane stretch independently control K+ channel activity
A marriage of convenience: beta-subunits and voltage-dependent K+ channels.
Ion-channel reconstitution.
S3b amino acid residues do not shuttle across the bilayer in voltage-dependent Shaker K+ channels
S3b amino acid residues do not shuttle across the bilayer in voltage-dependent Shaker K+ channels
External copper inhibits the activity of the large-conductance calcium- and voltage-sensitive potassium channel from skeletal muscle
External copper inhibits the activity of the large-conductance calcium- and voltage-sensitive potassium channel from skeletal muscle

BookSection (2)

Voltage-Dependent K+ Channels
Ion-Channel Reconstitution

JournalWhole (1)

Identification and expressional analysis of NLRC5 inflammasome gene in smolting Atlantic salmon (Salmo salar)

Patent (1)

MÉTODO PARA LA DETECCIÓN DE LA ESMOLTIFICACIÓN EN SALMO SALAR, OLIGONUCLEÓTIDOS Y KIT UTILIZADOS/ METHOD FOR THE DETECTION OF THE ENMOLTIFICATION IN SALMO SALAR, OLIGONUCLEÓTIDOS AND KIT USED.

Proyecto (12)

CHARACTERIZATION OF THE SIDE-EFFECTS OF THE MOST COMMONLY USED ANTIBIOTICS FOR FARMING SALMO SALAR AND ONCORHYNCHUS KISUTCH ON FISH PHYSIOLOGY AND EVALUATION OF TWO STRATEGIES FOR MINIMIZING THESE SIDE-EFFECTS: TREATMENT FREQUENCY AND DIET ADDITIVES."
Improving accuracy in the timing of smolt transfer and their performance in seawater=> A comparative study of several molecular markers expressed in gills of Atlantic salmon through real-time PCR.
“Improving accuracy in the timing of smolt transfer and their performance in seawater: A comparative study of several molecular markers expresed in gills of Atlantic salmon by real-time PCR.”
Programa Tecnológico Corfo "Desarrollo Integral del cultivo de bacalao de profundidad para el escalamiento sustentable y el fortalecimiento de la competitividad del Clúster Acuícola chileno"
Transmission of P. salmonis and Francisella sp from farmed salmon to native fish species and vice-versa=> Possible new routes of spreading high risk pathogens for aquaculture
“Transmission of P. salmonis and Francisella sp from farmed salmon to native fish species and vice-versa: Possible new routes of spreading high risk pathogens for aquaculture”
“Programa de Cultivo de Bacalao de Profundidad”
EXPRESSION OF HIGH-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM (BK) CHANNELS IN GILLS OF SALMO SALAR DURING ACCLIMATION TO SEAWATER=> TOWARD A NEW MOLECULAR MARKER OF SMOLTIFICATION
Expression of high-conductance calcium-activated potassium (BK) channels in gills of Salmo salarduring acclimation to seawater: Toward a new molecular marker of smoltification
“DESARROLLO DE UN KIT DE PCR EN TIEMPO REAL PARA LA DETERMINACIÓN DE LA SMOLTIFICACIÓN EN SALMO SALAR”
Busqueda del canal BK en salmonidos=> hacia un posible marcador molecular de la adaptacion a aumentos de la salinidad.
Investigacion aplicada de un extracto de fruto de maqui para el control de la glicemia en pacientes con Diabetes tipo II.

Review (1)

A marriage of convenience: beta-subunits and voltage-dependent K+ channels
46
Francisco Morera

Assistant Professor

Pontificia Universidad Católica de Chile

Santiago, Chile

14
Luis Vargas

Full Professor

Universidad Austral de Chile

Valdivia, Chile

10
Ricardo Oyarzun

Investigador, apoyo en investigación científica

Instituto de Ciencias Marinas y Limnológicas

Universidad Austral de Chile

Valdivia, Chile

8
José Muñoz

investigador, academico

CENTRO I-MAR, UNIVERSIDAD DE LOS LAGOS

Puerto Montt, Chile

8
ramon latorre

Profesor

Instituto de Neurociencia

Universidad de Valparaíso

5, Chile

4
Margarita González

Docente investigador

Facultad de Ciencias de la Naturaleza

Universidad San Sebastián

Puerto Montt, Chile

4
Juan Pontigo

Academico-Investigador

Medicina Veterinaria

Universidad San Sebastián

Puerto Montt, Chile

3
GONZALO MARDONES

Associate Professor

Medicine

Universidad San Sebastián

Valdivia, Chile

2
Karen Castillo

Académica Investigadora

,Centro de Investigación de Estudios Avanzados del Maule (CIEAM)

Universidad Catolica del Maule

Talca, Chile

2
Carlos Loncoman

Profesor auxiliar

Instituto de Bioquimica y Microbiologia

Universidad Austral de Chile

Valdivia, Chile

2
Angara Zambrano

Assistant Professor

Biochemistry and Microbiology

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

1
Alfredo Ramírez

Profesor Asociado

Instituto de Ciencia Animal

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

1
Pablo Alarcón

Profesor a honorarios

CFT Santo Tomas

valdivia, Chile

1
Javier Ojeda

Docente instructor en el INstituto de Ciencias Clínicas Veterinarias.

Universidad Austral de Chile

Valdivia, Chile

1
Patricio Sánchez

Asistente de Investigación

Departamento de Biología

Centro de Estudios Científicos

Valdivia, Chile

1
Rafael Burgos

FULL PROFESSOR

PHARMACOLOGY AND MORPHOPHYSIOLOGY

UNIVERSIDAD AUSTRAL DE CHILE

VALDIVIA, Chile

1
Ingrid Carvacho

Assistant Professor

Medicina Traslacional

Universidad Católica del Maule

Talca, Chile

1
Alejandro Yanez

Full professor

Faculty of Science

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

1
Alan Neely

Pofesor

Instituto de Neurociencias

Universidad de Valparaíso

Valparaiso, Estados Unidos

1
Pablo Strobel

Prrofesional de laboratorio

Facultad Ciencias Veterinarias

Universidad Austral de Chile

Valdivia, Chile

1
Claudio Henríquez

Associate Professor

Farmacology and Morphophysiology

Universidad Austral de Chile

Valdivia, Chile

1
Manuel Moroni

Académico

Instituto de Patología Animal

Universidad Austral de Chile

Valdivia, Chile

1
Gerardo Acosta

Full Professor

INSTITUTO DE MEDICINA PREVENTIVA VETERINARIA, FACULTAD DE CIENCIAS VETERINARIAS, UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

1
Juan Opazo

Profesor Titular

Facultad de Medicina y Ciencia

Universidad San Sebastián

Valdivia, Chile

1
Agustin Martinez

Profesor Titular

Instituto de Neurociencia

UNIVERSIDAD DE VALPARAÍSO, CENTRO INTERDISCIPLINARIO DE NEUROCIENCIAS DE VALPARAÍSO

Valparaíso, Chile

1
PATRICIA BURGOS

Associate Professor Programa de Doctorado en Biología Celular y Biomedicina CEBICEM

UNIVERSIDAD SAN SEBASTIÁN

Santiago, Chile

1
Yennyfer Arancibia

Docente-Investigadora

Ciencias Biológicas y Químicas

Universidad San Sebastián

Puerto Montt, Chile

1
Cecilia Vergara

Profesor Asociado

Biología

DEPARTAMENTO BIOLOGIA, FACULTAD DE CIENCIAS, U. DE CHILE

Santiago, Chile