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Pablo Andrés Alarcón Uribe

Profesor a honorarios

CFT Santo Tomas

valdivia, Chile

farmacologia molecular; inmunologia; biologia celular

Doctorado en Ciencias Mención Biología Celular y Molecular, UNIVERSIDAD AUSTRAL DE CHILE. Chile, 2017

Asistente de investigación, FONDECYT 1090401 Full Time

Universidad Austral de Chile

Chile

2009 - 2010
Personal de apoyo en laboratorio de biología molecular Full Time

AQUAGESTION S.A.

Puerto Montt, Chile

2009 - 2009
Tesista de Pregrado, FONDEF D04I1240 Full Time

Universidad Austral de Chile

Valdivia, Chile

2008 - 2009
Profesor a honorarios Part Time

CFT Santo Tomas

Valdivia, Chile

2015 - 2018
Tesista de Doctorado, Fondecyt 1120718 Full Time

Universidad Austral de Chile

Valdivia, Chile

2013 - 2016
Investigador Postdoctoral Full Time

Universidad Austral de Chile

Valdivia, Chile

2017 - 2020
Profesor Ad honorem Part Time

Universidad Austral de Chile

Valdivia, Chile

2017 - At present


Equine bone marrow-derived mesenchymal stromal cells inhibit reactive oxygen species production by neutrophils Espinosa G.; Plaza A.; Schenffeldt A.; AlarcÃ³n P.; Gajardo G.; Uberti B.; MorÃ¡n G.; HenrÃquez C. Article ISI SCOPUS (2020)
Glycolysis and mitochondrial function regulate the radical oxygen species production induced by platelet-activating factor in bovine polymorphonuclear leukocytes Quiroga, John; Alarcón, Pablo; Manosalva, Carolina; Taubert, Anja; Hermosilla, Carlos; Hidalgo, María Angélica; Carretta, María Daniella; Burgos, Rafael Agustín Article Veterinary Immunology and Immunopathology (2020)
Oleic and Linoleic Acids Induce the Release of Neutrophil Extracellular Traps via Pannexin 1-Dependent ATP Release and P2X1 Receptor Activation Alarcón, Pablo; Manosalva, Carolina; Quiroga, John; Belmar, Isidora; Álvarez, Karina; Díaz, Gustavo; Taubert, Anja; Hermosilla, Carlos; Carretta, María D.; Burgos, Rafael A.; Hidalgo, María A. Article FRONTIERS IN VETERINARY SCIENCE (2020)
Searching for Drug Synergy Against Cancer Through Polyamine Metabolism Impairment: Insight Into the Metabolic Effect of Indomethacin on Lung Cancer Cells LÃ³pez-Contreras F.; MuÃ±oz-Uribe M.; PÃ©rez-Laines J.; Ascencio-Leal L.; Rivera-Dictter A.; Martin-Martin A.; Burgos R.A.; Alarcon P.; LÃ³pez-MuÃ±oz R. Article ISI SCOPUS FRONTIERS IN PHARMACOLOGY (2020)
Vincristine, carboplatin and cisplatin increase oxidative burst induced by PAF in canine neutrophils Mendez N.; AlarcÃ³n P.; MillÃ¡n C.; Burgos R.A.; Morera F.J.; Ojeda J. Article ISI SCOPUS (2020)
Docosahexaenoic acid and TUG-891 activate free fatty acid-4 receptor in bovine neutrophils Olmo I.; Teuber S.; Larrazabal C.; Alarcon P.; Raipane F.; burgos R.A.; Hidalgo M. A. Article ISI SCOPUS VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY (2019)
Functional expression of the free fatty acids receptor-1 and-4 (FFA1/GPR40 and FFA4/GPR120) in bovine endometrial cells Valenzuela, Pamela; Teuber, Stefanie; Manosalva, Carolina; Alarcón, Pablo; Figueroa, Carlos D.; Ratto, Marcelo; Burgos, Rafael A.; Hidalgo, Maria A. Article ISI SCOPUS VETERINARY RESEARCH COMMUNICATIONS (2019)
Metabolic disturbances in synovial fluid are involved in the onset of synovitis in heifers with acute ruminal acidosis Alarcon, Pablo; Hidalgo, Alejandra, I; Manosalva, Carolina; Cristi, Raul; Teuber, Stefanie; Hidalgo, Maria A.; Burgos, Rafael A. Article ISI SCOPUS SCIENTIFIC REPORTS (2019)
Pro-inflammatory mediators and neutrophils are increased in synovial fluid from heifers with acute ruminal acidosis Hidalgo A.I.; Carretta M.D.; AlarcÃ³n P.; Manosalva C.; MÃ¼ller A.; Navarro M.; Hidalgo M.A.; Kaehne T.; Taubert A.; Hermosilla C.R.; Burgos R.A. Article ISI SCOPUS BMC VETERINARY RESEARCH (2019)
D(-) Lactic Acid-Induced Adhesion of Bovine Neutrophils onto Endothelial Cells Is Dependent on Neutrophils Extracellular Traps Formation and CD11b Expression Alarcón P.; Manosalva C.; Conejeros I.; Carretta M.D.; Muñoz-Caro T.; Silva L.M.R.; Taubert A.; Hermosilla C.; Hidalgo M.A.; Burgos R.A. Article ISI SCOPUS FRONTIERS IN IMMUNOLOGY (2017)
Application of a real-time PCR assay to detect BK potassium channel expression in samples from Atlantic salmon (Salmo salar) and Rainbow trout (Oncorhynchus mykiss) acclimated to freshwater Loncoman, CA; Gutierrez, L; Strobel, P; Alarcon, P; Contreras, C.; Conejeros, I; Morera, FJ Article Archivos de medicina veterinaria (2015)
Eimeria bovis-triggered neutrophil extracellular trap formation is CD11b-, ERK 1/2-, p38 MAP kinase- and SOCE-dependent Muñoz-Caro, Tamara; Mena Huertas, Sandra Jaqueline; Conejeros, Ivan; Alarcón, Pablo; Hidalgo, María A; Burgos, Rafael A.; Hermosilla, Carlos; Taubert, Anja Article ISI VETERINARY RESEARCH (2015)
Oxidative response of neutrophils to platelet-activating factor is altered during acute ruminal acidosis induced by oligofructose in heifers Concha, Claudia; Carretta, María Daniella; Alarcón, Pablo; Conejeros, Ivan; Gallardo, Diego; Hidalgo, Alejandra Isabel; Tadich, Nestor; Cáceres, Dante Daniel; Hidalgo, María Angélica; Burgos, Rafael Agustín Article ISI SCOPUS JOURNAL OF VETERINARY SCIENCE (2014)
2-Aminoethoxydiphenyl borate (2-APB) reduces alkaline phosphatase release, CD63 expression, F-actin polymerization and chemotaxis without affecting the phagocytosis activity in bovine neutrophils Conejeros, I; Velasquez Z.D.; Carretta, M.D.; Alarcon, P; Hidalgo, M.A; Burgos, R.A. Article VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY (2012)
2-Aminoethoxydiphenyl borate (2-APB) reduces respiratory burst, MMP-9 release and CD11b expression, and increases l-selectin shedding in bovine neutrophils. Conejeros, I; Jara, E; Carretta, M D; Alarcón, P; Hidalgo, M A; Burgos, R A Article Research in veterinary science (2012)
D-lactic acid interferes with the effects of platelet activating factor on bovine neutrophils. Alarcón, P; Conejeros, I; Carretta, M D; Concha, C; Jara, E; Tadich, N; Hidalgo, M A; Burgos, R A Article Veterinary immunology and immunopathology (2011)
Andrographolide reduces IL-2 production in T-cells by interfering with NFAT and MAPK activation Carretta, MD; Alarcon, P; Jara, E; Solis, L; Hancke JL; Concha, II; Hidalgo, MA; Burgos, RA Article EUROPEAN JOURNAL OF PHARMACOLOGY (2009)


ROL DE LOS RECEPTORES PURINÉRGICOS Y ATP EN LA ACTIVACIÓN DEL NEUTRÓFILO DE BOVINO INDUCIDO POR NEFAS FONDECYT (3170775) Proyecto 2017-2020 Inv. Responsable
LONG CHAIN FATTY ACIDS AS MODULATORS OF BOVINE INNATE IMMUNITY. ROLE OF FREE FATTY ACID (FFA)-1 AND FFA4 RECEPTORS. FONDECYT (1151047) Proyecto 2015-2018 Personal técnico y/o de apoyo
LONG CHAIN FATTY ACIDS AS MODULATORS OF BOVINE INNATE IMMUNITY. ROLE OF FREE FATTY ACID (FFA)-1 AND FFA4 RECEPTORS. FONDECYT (1151047) Proyecto 2015-2018 Personal técnico y/o de apoyo
CONSOLIDACIÓN E INTERNACIONALIZACIÓN DE LOS PROGRAMAS DE DOCTORADOS PARA AUMENTAR LA COMPETITIVIDAD Y PRODUCTIVIDAD DE LA UACH EN LAS ÁREAS ESTRATÉGICAS DE BIOCIENCIAS, BIOTECNOLOGÍA Y CIENCIAS VETERINARIAS , COMO BASES DEL DESARROLLO SOCIAL Y PRODUCTIVO MECESUP AUS 1203 (AUS 1203) Proyecto 2013-2013 Inv. Patrocinante
Ácido D-láctico modula la formación de NETs (Neutrophils extracellular Traps) y la adhesión del neutrófilo sobre el endotelio vascular. PFCHA (21110189) Proyecto 2013-2014 Inv. Responsable
D-LACTATAEMIA INCREASES THE BOVINE BLOOD NEUTROPHIL ACTIVITY AND IS ASSOCIATED WITH THE EARLY ONSET OF LAMINITIS IN HEIFER WITH ACUTE RUMINAL ACIDOSIS FONDECYT (1120718) Proyecto 2012-2014 Tesista
Inmunidad Innata=> Efecto de la temperatura sobre la función de Neutrófilos Bovinos EXPLORA (s/n) Proyecto 2012-2012 Coinvestigador(a)
D-Lactataemia Increases the Bovine Blood Neutrophil Activity and Is Associated with the Early Onset of Laminitis in Heifer with Acute Ruminal Acidosis FONDECYT (1120718) Proyecto 2011-2014 Tesista
ROLE OF NEUTROPHILS IN THE ONSET OF BOVINE LAMINITIS. STUDY OF ACIDOSIS AS NEUTROPHILS PRIMING INDUCER AGENT FONDECYT (1090401) Proyecto 2009-2012 Personal técnico y/o de apoyo
ROLE OF NEUTROPHILS IN THE ONSET OF BOVINE LAMINITIS. STUDY OF ACIDOSIS AS NEUTROPHILS PRIMING INDUCER AGENT FONDECYT (1090401) Proyecto 2009-2012 Personal técnico y/o de apoyo
EVALUACION DE LA EFICACIA INMUNOMODULADORA DE UNA COMPOSICION DE LABDANOS DITERPENICOS Y DESARROLLO DE NUEVOS ANALOGOS SINTETICOS FONDEF (D04I1240) Proyecto 2007-2008 Tesista


Fatty and hydroxycarboxylic acid receptors: The missing link of immune response and metabolism in cattle Alarcon, P; Manosalva C.; Carretta, MD; Hidalgo, AI; Figueroa, CD; Taubert, A; Herrnosilla, C; Hidalgo, MA; Burgos, RA Review ISI SCOPUS VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY (2018)