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Juan Cristóbal Maass Oñate

Asistan Professor

universidad de chile

Santiago, Chile

Líneas de Investigación


Inner ear regeneration and development Hearing loss genetics and genomics Otolaryngology Otology and Neuro-otology Sudden deafness Artificial Intelligence-aided diagnosis

Educación

  •  Doctor en Ciencias Medicas mencion en otorrinolaringologia, Universidad de Chile. Chile, 2010
  •  Medico cirujano, Universidad de Chile. Chile, 2001
  •  Otorrinolaringologia, Universidad de Chile. Chile, 2005

Experiencia Académica

  •   Assistant Professor Part Time

    Universidad de Chile

    Medicina

    Santiago, Chile

    2013 - At present

  •   Assistant Professor Part Time

    UNIVERSIDAD DE CHILE

    Medicina

    Santiago, Chile

    2005 - At present

  •   Postdoctoral associate Full Time

    BAYLOR COLLEGE OF MEDICINE

    Houston, Estados Unidos

    2010 - 2012

Experiencia Profesional

  •   Assistant Professor Part Time

    University of Chile

    Santiago, Chile

    2005 - At present

  •   Otolaryngologist Part Time

    Clinica Alemana-Universidad del Desarrollo

    Santiago, Chile

    2008 - At present

  •   Otolaryngologist Part Time

    Hospital Clínico Universidad de Chile

    Santiago, Chile

    2005 - At present

Formación de Capital Humano


Undergraduate education
Tesis seminar: Validación de la expresión espacio-temporal de genes del oído interno en ratón postnatal y su posible uso con fin terapéutico, Silvia Cantelllano 2014
Graduate Education
MD PhD Tesis: Disminución de la expresión génica de Notch1 como aproximaciòn para la regeneración de células ciliadas y eventual tratamiento para la hipoacusia. Francisca Leon 2019


Premios y Distinciones

  •   Mejor trabajo cientifico congreso

    SOCIEDAD CHILENA DE OTORRINOLARINGOLOGIA

    Chile, 2018

    Best Podium presentation at the LXXV Otolaryngology, Head and Neck Chilean Congress. Santa Cruz, Chile.

  •   Mejor trabajo cientifico congreso

    SOCIEDAD CHILENA DE OTORRINOLARINGOLOGIA

    Chile, 2010

    Best Podium presentation at the LVII Otolaryngology, Head and Neck Chilean Congress. Valdivia, Chile


 

Article (14)

Computer-aided diagnosis of external and middle ear conditions: A machine learning approach
Preventing presbycusis in mice with enhanced medial olivocochlear feedback
Reduced suprathreshold auditory nerve responses are associated with slower processing speed and thinner temporal and parietal cortex in presbycusis
p27(Kip1) down-regulation as achieved by two clinically feasible means did not induce proliferation of supporting cells in the rat neonatal cochlea in vivo
SFPQ associates to LSD1 and regulates the migration of newborn pyramidal neurons in the developing cerebral cortex
Transcriptomic Analysis of Mouse Cochlear Supporting Cell Maturation Reveals Large-Scale Changes in Notch Responsiveness Prior to the Onset of Hearing
Changes in the regulation of the Notch signaling pathway are temporally correlated with regenerative failure in the mouse cochlea
The Specification of Cortical Subcerebral Projection Neurons Depends on the Direct Repression of TBR1 by CTIP1/BCL11a
SÍNTOMAS LARÍNGEOS Y LARINGITIS POSTERIOR: ¿SIEMPRE ES SECUNDARIO A REFLUJO GASTROESOFÁGICO?
Analysis of FGF-Dependent and FGF-Independent Pathways in Otic Placode Induction
p27Kip1 Knockdown Induces Proliferation in the Organ of Corti in Culture after Efficient shRNA Lentiviral Transduction
CoREST represses the heat shock response mediated by HSF1
Estudio morfológico del oído medio e interno de la Chinchilla laniger
Efecto del factor de crecimiento endotelio vascular (VEGF) sobre perforaciones timpánicas en ratas Long-Evans

BookSection (1)

Hair Cell Regeneration

Proyecto (14)

IDENTIFYING MUTATIONS THAT CAUSE CONGENITAL DEAFNESS IN CHILE
Efferent neural dynamics from auditory cortex to the cochlear receptor during selective attention paradigms in tinnitus patients and chinchillas
EFFERENT NEURAL DYNAMICS FROM AUDITORY CORTEX TO THE COCHLEAR RECEPTOR DURING SELECTIVE ATTENTION PARADIGMS IN TINNITUS PATIENTS AND CHINCHILLAS
International network for Auditory and Cognition Center (Chile-Argentina)
From presbycusis to dementia: a basic and clinical approach
“Otobanco=> Banco de muestras de DNA de pacientes con enfermedades otorrinolaringológicas infrecuentes u origen genético”
“Predisposición genética en la respuesta a cortico-esteroides y su asociación con el resultado auditivo final en pacientes con hipoacusia súbita”
Supporting cell next generation gene expression profile in the purse of an inducible and sequential proliferation-transdifferentiation approach for a more efficient and stable cochlear regenerative response in vivo
Supporting cell next generation gene expression profile in the pursuit of an inducible and sequencial proliferation-transdifferentiation approach for a more efficient and stable cochlear regenerative esponse in vivo
Treating combat hearing loss with Atoh1 Gene Therapy
Interferencia en la expression de genes en el oído interno como herramienta molecular para regenerar células ciliadas (apoyo tesis doctoral)
Molecular interference as tool for Inner Ear Regeneration
Interferencia en la expression de genes en el oido interno como herramienta molecular para regenerar células ciliadas
Identification of mutations causing genetic deafness in Chile

Review (1)

Terapia génica como herramienta molecular para regenerar células ciliadas
23
Juan Maass

Asistan Professor

universidad de chile

Santiago, Chile

3
Paul Delano

Associate Professor

1.Otolaryngology/2. Physiology and Biophysics

UNIVERSIDAD DE CHILE

Santiago, Chile

2
María Andrés

Full Professor

Cellular and Molecular Biology

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Gonzalo Terreros

Assistant Professor

Instituto de Ciencias de la Salud

Universidad de O'Higgins

Rancagua, Chile

1
Michelle Viscaino

PhD (c)

Departamento de electrónica

Universidad Técnica Federico Santa María

Valparaíso, Chile

1
Fernando Auat

Associate Professor

DEPARTAMENTO DE ELECTRÓNICA, UNIVERSIDAD TÉCNICA FEDERICO SANTA MARÍA

Valparaiso, Chile

1
CAROLINA DELGADO

ASSOCIATE PROFESSOR

NEUROLOGÍA y neurocirugía

HOSPITAL CLINICO UNIVERSIDAD DE CHILE

SANTIAGO, Chile

1
Andrea Gómez

Investigador Postdoctoral

Fisiología

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Carlos Oliva

Profesor Asociado

Biología Celular y Molecular

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Rodrigo Aguilar

Assistant Professor

Institute for Biomedical Sciences

Universidad Andrés Bello

Santiago, Chile

1
Jimena Sierralta

Full Professor

Neuroscience

Faculty of Medicine, Universidad de Chile

Santiago, Chile

1
Martín Montecino

Director

Institute of Biomedical Sciences

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

1
Katherine Saud

Lab Manager

Terapia Celular

Bioscell S.A.

Santiago, Chile

1
Rodrigo Vergara

Investigador

Psicología

Universidad San Sebastián

Valdivia, Chile