Jimena Alejandra Sierralta Jara
Full Professor
Faculty of Medicine, Universidad de Chile
Santiago, Chile
Research lines, A Scaffold proteins in synaptic function and plasticity. B Genes involved in neuronal morphogenesis C Neuronal-Glia energetic relationship D Blood-Brain barrier. Collaborations LF Barros; Maldonado PE; Olguín P; Oliva C,
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biochemistry, Pontificia Universidad Católica de Chile. Chile, 1988
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Sciences, BIology, UNIVERSIDAD DE CHILE. Chile, 1996
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Biochemist, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 1988
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Associate Professor Full Time
UNIVERSIDAD DE CHILE
Faculty of Medicine
Santiago, Chile
2004 - At present
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Assistant Professor Full Time
UNIVERSIDAD DE CHILE
Faculty of Medicine
Santiago, Chile
1998 - 2004
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Full Professor Full Time
UNIVERSIDAD DE CHILE
Medicina
Santiago, Chile
2017 - At present
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Full Professor Full Time
Universidad de Chile
Santiago, Chile
1998 - At present
Undergraduate thesis
Mrs Gabriela Lafferte (2001), Biochemistry thesis, Universidad de Chile; Mrs. Ximena Martínez, Veterinary thesis (2001), Universidad de Chile; Mrs. Mirna Cruz Engineer in Biotechnology thesis (2003), Universidad de Chile; Mrs. Romina Barría, Biochemistry thesis(2004), Mrs Valeria Albornoz (2004), Biochemistry thesis, Mr. Francisco Urra, Biochemistry thesis, (2005) Mr. Pablo Majóo, Biochemistry thesis (2006), Mr. Gabriel Pavez Biochemistry thesis (2014), Mrs Gabriela Insunza Veterinary thesis (2008), Hector Pacheco, Veterinary thesis (2009). Mr Orlando Chávez (2009) Informatic Engineer, Universidad de Talca, Mrs Pía Escobedo (2010), Biochemistry thesis Faculty of Sciences, Pontificia Universidad Católica de Valparaíso, Mauricio Ramírez (2011) Biology, Pontificia Universidad Católica de Valparaíso, Guillermo Moya (2012), Biochemistry thesis Universidad de Santiago, Diego Villegas, P.Universidad Católica de Chile, (2019) Biochemistry thesis
Graduate thesis
Carolina Mendoza PhD (2003-2006), Carlos Oliva PhD thesis (2007-2010), César Astorga Ph.D. thesis (2010-2014), José Cánovas, Co-advisor Ph.D. thesis (2009-2014), MGraciela Delgado Ph.D. thesis (2012-1015), Cristian de Gregorio, Co-advisor PhD Thesis (2012-2015) Francisca Bertín PhD Thesis (2017-2020), Javiera Gallardo (2018-2020) co-advisor, Andrés Kohler (2018-2021). Ximena Martínez Ms Thesis (2007-2008), Claudia Molina Ms Thesis (2009-2010), Giovanna Otarola Ms Thesis (2009-2010), Ignacio Herrera co-advisor MsThesis in Neuroscience (2014-2015), Francisca Bertín (2014-2015) MsThesis in Neuroscience.Andrés Ibacahe (2017-2018) Ms thesis in genetics.
Current PhD students: Aline Ovalle, co advisor; Andrés Ibacache, co-advisor.
Current Ms students: Liliana Spindola Ms in Neuroscience
Current Undergraduate: Rocío Verdugo , Diego Manque
Postdocs
Dr. Alvaro Glavic (2005-2006)
Dr. Diego Rojas (2013-2015)
Dr. Carlos Oliva (2014-2016)
Dr. Esteban Contreras (2015-2019)
Dr. Andrés González (2016-2020)
Teaching Graduate: Lectures in the following courses for PhD students, Cellular Biology (2000-2004), Molecular Endocrinology (2000-2003), Cellular Physiology (2000-2007), Advance Molecular Biology (2004-to-now), Introduction to Neuroscience (2004-to now), Advance Neuroscience (2001-to now) all of the Biomedical Science Program of the Faculty of Medicine. Organizer and teacher at the course Invertebrate Neurobiology (2006-)
International Workshops / Courses
Lectures in IBRO International School of Neuroscience, 2004 and 2006; Neurobiology of Drosophila (Organizer), 2003. Invited to the International Practical Course Neural Development, Montevideo, Uruguay
International Course Small Brains Big Ideas: Biomedical Insight from Invertebrate Research (Co-Organizer); www.smallbrains.org, 2010, 2012, 2014, 2016, 2019, 2022, 2024.
2023 Vice-president of the Biomedical Neuroscience (BNI) Institute Corporation
2021-2023 President Chilean Society of Biology
2022 President of the Biomedical Neuroscience Institute Corporation
2018-2021Deputy director of the Biomedical Neuroscience Institute
2018 to date Director of the Education (www.mentestranformadoras.cl) and dissemination (www.loligo.cl) Program at BNI
2017 Invited reviewer for the Canadian Grant competition
2015 Invited Member in the adjudication panel Canadian-Israel Program Grants
2009-2013 Member of the national committee for the selection of candidates to the Pew Latin American Fellowship. 2012-2013, President of the national committee.
2009-2021 President of the committee of the Master in Neuroscience Program, Faculty of Medicine, U. de Chile
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Pew Latinamerican Fellowship
PEW LATIN AMERICAN FELLOWS PROGRAM IN BIOMEDICAL SCIENCES
Estados Unidos, 1996
Fellowship to do a postdoctoral training. I did 2 years at the laboratory of Dr. Charles ZUker at UCSD, La Jolla
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Conicyt Fellowship
CONSEJO NACIONAL PARA INVESTIGACIONES CIENTIFICAS Y TECNOLOGICAS
Chile, 1989
Fellowship to carry out a PhD Program, at the Universidad de Chile
How doth the little busy bee: unexpected metabolism |
Presynaptic calcium signal in glutamatergic synapses=> role of scaffold proteins in its modulation. |
Role of the putative monocarboxylate transporter CG3409 (chaski) on the adaptive response of Drosophila melanogaster to nutritional restriction during development |
Biomedical Neuroscience Institute (BNI) |
Drosophila Ring in Developmental Adaptations to Nutritional Stress (DRiDANS) |
Drosophila Ring in developmental adaptations to nutritional stress |
The cell biology of hereditary spastic paraplegias using Drosophila as a model organism |
FINE TUNNING OF THE UPR=> FUNCTIONAL ANALYSIS OF THE IRE1ALPHA INTERACTOME |
Instituto de Neurociencia Biomédica |
MECHANISMS OF CELL ADAPTATION TO INTER-TISSUE MECHANICAL STRESS DURING MORPHOGENESIS, THE ROLE OF DROSOPHILA FILAMIN(JITTERBUG) AND CHASCON. |
ROLE OF THE DROSOPHILA MAGUK PROTEIN DLGS97 IN LEARNING AND MEMORY |
Núcleo de Morfogénesis Neuronal. |
ROLE OF DROSOPHILA DLG IN SYNAPTIC PLASTICITY |
ROLE OF REST/NRSF, COREST AND MIR124A DURING NEUROGENESIS AND NEURONAL DIFFERENTIATION IN VIVO |
Centro para el análisis de la función génica en el desarrollo neural. |
ESTUDIO DE LA FUNCION DEL GEN DE DROSOPHILA D-AXUD1 COMO SUPRESOR TUMORAL Y EN EL MANTENIMIENTO DE LA INTEGRIDAD EPITELIAL, Y DE SUS INTERACCIONES CON LA RUTAS DE SENALIZACION TGF-BETA Y WNT. |
PAPEL DE CANALES DE CALCIO EN EL ESTABLECIMIENTO DEL PATRON DORSOVENTRAL EN EL EMBRION DE XENOPUS LAEVIS. |
PAPEL DE PRODUCTOS DE DLG EN LA DIVISION ASIMETRICA DE NEUROBLASTOS EN DROSOPHILIA |
PAPEL DE PRODUCTOS DE DLG EN LA DIVISION ASIMETRICA DE NEUROBLASTOS EN DROSOPHILIA |
PAPEL DE PRODUCTOS DE DLG EN LA DIVISION ASIMETRICA DE NEUROBLASTOS EN DROSOPHILIA |
PAPEL DE DlgB EN LA LOCALIZACION DE INAD Y EL COMPLEJO DE FOTOTRANSDUCCION DE DROSOPHILA MELANOGASTER |
ACTIVACION DE CANALES DE LIBERACION DE CA2+ SENSIBLES A RYANODINA FOTOLISIS DE COMPUESTOS ENJAULADOS. ACOPLAMIENTO CITOSOL-LUMEN Y MODOS DE ACTIVACION DE CONDICIONES DE ALTA RESOLUCION TEMPORAL |
CARACTERIZACION BIOQUIMICA Y ELECTROFISIOLOGICA DE LOS CANALES DE LIBERACION DE CALCIO PRESENTES EN EL RETICULO ENDOPLASMICO DE LAS NEURONAS DE HIPOCAMPO. |
SINTESIS Y DEGRADACION DE INOSITOL TRISFOSFATO EN MUSCULO ESQUELITICO |