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Gonzalo Alberto Olivares Herane

ASSISTANT PROFESSOR

Universidad de Chile

SANTIAGO, Chile

Líneas de Investigación


- Adult stem cells differentiation in Drosophila - Alternative polyadenylation of transcripts during male germline differentiation in Drosophila - Quantitative genetics of complex traits (sleep) in Drosophila - Gene by environment interaction

Educación

  •  Ciencias Biológicas mención Biología Celular y Molecular, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2007
  •  Licenciatura en Bioquímica, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2001
  •  Bioquímico, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2005

Experiencia Académica

  •   ASSISTANT PROFESSOR Part Time

    UNIVERSIDAD DE CHILE

    FACULTAD DE MEDICINA

    SANTIAGO, Chile

    2018 - At present

  •   POSTDOC Full Time

    UNIVERSIDAD DE CHILE

    FACULTAD DE MEDICINA

    SANTIAGO, Chile

    2016 - 2018

  •   POSTDOC Full Time

    UNIVERSIDAD DE CHILE

    CIENCIAS

    SANTIAGO, Chile

    2015 - 2016

  •   POSTDOC Full Time

    STANFORD UNIVERSITY

    SCHOOL OF MEDICINE

    PALO ALTO, Estados Unidos

    2010 - 2015

  •   POSTDOC Full Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    CIENCIAS BIOLOGICAS

    SANTIAGO, Chile

    2008 - 2010

Formación de Capital Humano


Thesis Direction:
Students Names: Valentina Martínez Ruz – Rodrigo Neira Barrera
Thesis Title: “IDENTIFICACIÓN DE GENES QUE BRINDAN SUSCEPTIBILIDAD AL DESARROLLO DE FENOTIPOS PARKINSONIANOS EN EL ESTUDIO DE GEOTAXIS Y SOBREVIDA EN DROSOPHILA FRENTE A LA EXPOSICIÓN A ROTENONA”
Institution: Universidad San Sebastián
Degree: Licenciado en Tecnología Médica mención Morfofisiopatología y Citodiagnóstico

Student Name: Franco Daniel Núñez Villegas
Thesis Title: “Identificación de redes génicas de Drosophila melanogaster involucradas en la arquitectura del sueño y el efecto de condiciones nutricionales durante el desarrollo prenatal”
Institution: Universidad de Chile
Degree: Título profesional Bioquímico

Student Name: NOEMI CANDIA GONZÁLEZ
Thesis Title: “Identificación de redes de genes que subyacen a la susceptibilidad de desarrollar fenotipos parkinsonianos en respuesta a la exposición a rotenona en Drosophila melanogaster”
Institution: Universidad de Chile
Degree: MAGISTER EN GENÉTICA


Premios y Distinciones

  •   Gonzalo Olivares

    PEW LATIN AMERICAN FELLOWS PROGRAM IN BIOMEDICAL SCIENCES

    Estados Unidos, 2010

    Pew Latin American Fellowship, The Pew Latin American Fellows for postdoctoral training at Dr. Margaret Fuller laboratory Department of Developmental Biology, Stanford University

  •   Gonzalo Olivares

    American Heart Association (AHA)

    Chile, 2012

    WSA Postdoctoral Fellowship, American Heart Association (AHA) for postdoctoral training at Dr. Margaret Fuller laboratory, Department of Developmental Biology, Stanford University

  •   Gonzalo Olivares

    STANFORD UNIVERSITY

    Chile, 2010

    Dean’s Postdoctoral Fellowship, Stanford University School of Medicine for postdoctoral training at Dr. Margaret Fuller laboratory, Department of Developmental Biology, Stanford University.


 

Article (16)

Early-life nutrition interacts with developmental genes to shape the brain and sleep behavior in Drosophila melanogaster

Olivares, Gonzalo H.; Nunez-Villegas, Franco; Candia, Noemi; Orostica, Karen; Gonzalez-Ramirez, M. Constanza; Vega-Macaya, Franco; Zuniga, Nolberto; Molina, Cristian; Oliva, Carlos; Mackay, Trudy F. C.; Verdugo, Ricardo A.; Olguin, Patricio

Article ISI
SLEEP  (2023)

Identification of <i>atlastin</i> genetic modifiers in a model of hereditary spastic paraplegia in <i>Drosophila</i>

Candia, Noemi; Ibacache, Andres; Medina-Yanez, Ignacio; Olivares, Gonzalo H.; Ramirez, Mauricio; Vega-Macaya, Franco; Couve, Andres; Sierralta, Jimena; Olguin, Patricio

Article ISI
HUMAN GENETICS  (2023)

Low-nutrient diet in <i>Drosophila</i> larvae stage causes enhancement in dopamine modulation in adult brain due epigenetic imprinting

Zuniga-Hernandez, J. M.; Olivares, Gonzalo H.; Olguin, Patricio; Glavic, Alvaro

Article ISI
OPEN BIOLOGY  (2023)

Phosphatidic acid increases Notch signalling by affecting Sanpodo trafficking during Drosophila sensory organ development

Medina-Yáñez, Ignacio; Olivares, Gonzalo H.; Vega-Macaya, Franco; Mlodzik, Marek; Olguín, Patricio

Article
SCIENTIFIC REPORTS  (2020)

DREF Genetically Counteracts Mi-2 and Caf1 to Regulate Adult Stem Cell Maintenance

Angulo, Benjamin; Srinivasan, Shrividhya; Bolival, Benjamin J.; Olivares, Gonzalo H.; Spence, Allyson C.; Fuller, Margaret T.

Article ISI SCOPUS
PLOS GENETICS  (2019)

Modeling Parkinson's Disease Heterogeneity to Accelerate Precision Medicine

Olivares, Gonzalo H.; Olguin, Patricio; Klein, Andres D.

Article ISI SCOPUS
TRENDS IN MOLECULAR MEDICINE  (2019)

Jitterbug/Filamin and Myosin-II form a complex in tendon cells required to maintain epithelial shape and polarity during musculoskeletal system development

Manieu, Catalina; Olivares, Gonzalo H.; Vega-Macaya, Franco; Valdivia, Mauricio; Olguín, Patricio

Article ISI SCOPUS
Mechanisms of Development  (2018)

A Self-Limiting Switch Based on Translational Control Regulates the Transition from Proliferation to Differentiation in an Adult Stem Cell Lineage

Insco, Megan L.; Bailey, Alexis S.; Kim, Jongmin; Olivares, Gonzalo H.; Wapinski, Orly L.; Tam, Cheuk Ho; Fuller, Margaret T.

Article ISI
CELL STEM CELL  (2012)

Expression of Transposable Elements in Neural Tissues during Xenopus Development

Faunes, Fernando; Sánchez, Natalia; Moreno, Mauricio; Olivares, Gonzalo H.; Lee-Liu, Dasfne; Almonacid,Leonardo.; Slater, Alex W.; Norambuena, Tomas; Taft, Ryan J.; Mattick, John S.; Melo, Francisco; Larrain, Juan; Veenstra, Gert Jan C.

Article ISI SCOPUS
PLOS ONE  (2011)

SHh activity and localization is regulated by perlecan

Palma, V; Carrasco H.; Reinchisi G; Olivares, G; Faunes F.; Larrain, J

Article ISI SCIELO SCOPUS
Biological Research  (2011)

Non-canonical Wnt Signaling Induces Ubiquitination and Degradation of Syndecan

Carvallo L; Munoz, R.; Bustos F.; Escobedo N; Carrasco H.; Olivares, G; Larrain, J

Article ISI SCOPUS
Journal of Biological Chemistry  (2010)

Syndecan-1 regulates BMP signaling and dorso-ventral patterning of the ectoderm during early Xenopus development

Olivares, GH; Carrasco H.; Aroca, F; Carvallo L; Segovia, F; Larrain, J

Article ISI SCOPUS
DEVELOPMENTAL BIOLOGY  (2009)

Heparan sulfate proteoglycans exert positive and negative effects in Shh activity

Carrasco H.; Olivares, GH; Faunes F.; Oliva, C; Larrain, J

Article ISI SCOPUS
JOURNAL OF CELLULAR BIOCHEMISTRY  (2005)

Wnt-3a overcomes ?-amyloid toxicity in rat hippocampal neurons

Alvarez, A.R.; Godoy, J.A.; Mullendorff, K; Olivares G.H.; Bronfman, M; Inestrosa, N. C.

Article SCOPUS
EXPERIMENTAL CELL RESEARCH  (2004)

Activation of Wnt signaling and behavioral impairments rescues neurodegeneration induced by beta-amyloid fibrils

De Ferrari, GV; Chacón MA; Barría MI; garrido, JL; Godoy JA; Olivares, G; Reyes, AE; Alvarez A.; Bronfman, M; Inestrosa, NC

Article ISI SCOPUS
MOLECULAR PSYCHIATRY  (2003)

Wnt signaling involvement in beta-amyloid-dependent neurodegeneration

Inestrosa, NC; De Ferrari, GV; garrido, JL; Alvarez, A; Olivares, GH; Barria, MI; Bronfman, M; Chacon, MA

Article ISI
NEUROCHEMISTRY INTERNATIONAL  (2002)

Abstract (1)

Proteoglycan synthesis and function during early development of the vertebrate embryo.

Larrain, J; Carrasco H.; Leschot, A; Guzman, JP; Olivares, G; Moreno, M.

Abstract ISI
DEVELOPMENTAL BIOLOGY  (2003)

BookWhole (1)

WNT Signaling in Health and Disease

Larraín, Juan; Olivares, Gonzalo; Larrain, J; Olivares G.H.

BookWhole
 (2018)

Proyecto (1)

Alternative polydenylation and the regulation of male germ cell differentiation

Fuller, Margaret; Olivares G.H.

Proyecto The results of the proposed studies will reveal how a novel mode of gene regulation, developmentally controlled shortening of the 3'tails of transcripts, regulates expression of sets of proteins at specific stages of germ cell differentiation during spermatogenesis. The mechanisms we discover will p
 (2014)

Review (2)

Regulation and function of alternative polyadenylation in development and differentiation

Gallicchio, Lorenzo; Olivares, Gonzalo H.; Berry, Cameron W.; Fuller, Margaret T.

Review ISI
RNA BIOLOGY  (2023)

Trolox and 17 beta-estradiol protect against amyloid beta-peptide neurotoxicity by a mechanism that involves modulation of the Wnt signaling pathway

Quintanilla, RA; Muñoz FJ.; Metcalfe MJ; Hitschfeld, M; Olivares, G; Godoy JA; Inestrosa, NC

Review ISI SCOPUS
JOURNAL OF BIOLOGICAL CHEMISTRY  (2005)

21
Gonzalo Olivares

ASSISTANT PROFESSOR

NEUROCIENCIA

Universidad de Chile

SANTIAGO, Chile

6
Juan Agustín Larraín

Profesor Titular

Biologia Celular y Molecular

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

3
Nibaldo Inestrosa

Full Professor

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

3
Fernando Faunes

Profesor Asistente

Universidad Andrés Bello

Viña del Mar, Chile

3
Juan Godoy

Investigador

Centro de Oncologia dePrecision

Santiago, Chile

2
Francisco Melo

Profesor Titular

Genetica Molecular y Microbiologia

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

2
Carlos Oliva

Profesor Asociado

Biología Celular y Molecular

Pontificia Universidad Católica de Chile

Santiago, Chile

2
Patricio Olguín

Assistant Professor

Facultad de Medicina, ICBM, Departamento de Neurociencia

Universidad de Chile

Santiago, Chile

2
Jose Garrido

Investigador asesor, part time

Universidad San Sebastián

Puerto Montt, Chile

1
Giancarlo De Ferrari

Full Professor

Biological Sciences

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

1
Dasfne Lee-Liu

Postdoctoral Researcher

Biology

Universidad de Chile

Santiago, Chile

1
Ariel Reyes

Director de Departamento

Ciencias Biológicas

UNIVERSIDAD ANDRÉS BELLO

Santiago, Chile

1
Noelia Escobedo

Profesor Asistente

Facultad de Ciencias de la Salud

Universidad Autónoma de Chile

Talca, Chile

1
Ricardo Verdugo

Asistant Professor

Facultad de Medicina

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Marcelo Chacon

Postdoc

Neurology

UTHealth

Houston, Estados Unidos

1
ANDRES KLEIN

Assistant Professor/Director (Head) Center for Genetics and Genomics; Director, PhD Program in Sciences and Innovation in Medicine

Centro de Genética y Genómica

Universidad del Desarrollo-Clínica Alemana

SANTIAGO, Chile

1
Alex Slater

Profesor Asistente

Escuela de Biotecnología

Universidad Mayor

Santiago, Chile

1
Francisco Bustos Velasquez

Postdoctoral research assistant

School of Life Sciences

University of Dundee

Dundee, Reino Unido

1
Rodrigo Quintanilla

Associate professor

Universidad Autónoma de Chile

Santiago, Chile

1
Maria Barria

Investigador, Associate Professor

Universidad San Sebastián

Puerto Montt, Chile

1
Verónica Palma

Associate Professor

Biology

Universidad de Chile

Santiago, Chile

1
Jorge Zúñiga

Posdoctoral Researcher

Departamento de Biología

Universidad de Chile

Santiago, Chile

1
Verónica Palma

Profesor Titular

Biología

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Karen Oróstica

Vigilancia genómica

Genética Molecular

Universidad de Tal

Santiago, Chile

1
Tomás Norambuena

Group Lead del equipo de Data Science y Bioinformática

Data Science y Bioinformática

Meristem SpA

Santiago, Chile

1
Rosana Muñoz

postdoctorante

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Jimena Sierralta

Full Professor

Neuroscience

Faculty of Medicine, Universidad de Chile

Santiago, Chile