Man

LUIS FELIPE AGUILAR CAVALLO

PROFESOR ADJUNTO

PONTIFICIA UNIVERSIDAD CATOLICA DE VALPARAISO

VALPARAISO, Chile

Líneas de Investigación


Healthy Food; Cinética enzimática; Propiedades Fisicoquimicas de Bicapas lipidicas, Interaccion lipido-proteina; Tecnologias Fisicas de Conservacion de Alimentos; Diseño y analisis estructura-funcion de peptidos.

Educación

  •  Dr. en Ciencias con Mención en Química, PONTIFICIA UNIVERSIDAD CATOLICA DE VALPARAISO. Chile, 1999
  •  Químico, PONTIFICIA UNIVERSIDAD CATOLICA DE VALPARAISO. Chile, 1994

Experiencia Académica

  •   PROFESOR ADJUNTO Full Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE VALPARAISO

    FACULTAD DE CIENCIAS

    VALPARAÍSO, Chile

    2008 - At present

  •   JEFE DE CARRERA. INGENIERÍA EN BIOTECNOLOGÍA Full Time

    UNIVERSIDAD DE VIÑA DEL MAR

    VIÑA DEL MAR, Chile

    2004 - 2007

Experiencia Profesional

  •   PROFESOR CIVIL Part Time

    ESCUELA NAVAL ARTURO PRAT

    Valparaíso, Chile

    2002 - 2003


 

Article (48)

Combined 3D-QSAR and docking analysis for the design and synthesis of chalcones as potent and selective monoamine oxidase B inhibitors

Mella, Jaime; Aguilar, Luis F.

Article ISI
BIOORGANIC CHEMISTRY  (2021)

Evaluation of endemic Chilean plant-basedChanarextract (Geoffroea decorticans) as an inhibitor of corrosion for A36 steel under a saline environment

Chacon, Alexandra; Aguilar, Luis F.

Article ISI
MATERIALS AND CORROSION-WERKSTOFFE UND KORROSION  (2021)

Synthesis, Crystal Structure, and Photophysical Properties of 4-(4-(Dimethylamino)phenyl)-6-phenylpyrimidin-2-amine

Fuentealba, Mauricio; Bravo, Manuel A.; Aguilar, Luis F.

Article ISI
JOURNAL OF MOLECULAR STRUCTURE  (2021)

An in vitro study on the interaction of the anti-Alzheimer drug rivastigmine with human erythrocytes

Aguilar L.F.

Article ISI SCOPUS
 (2020)

Characterization of a new molecule capable of inhibiting several steps of the amyloid cascade in Alzheimer's disease

Peters, Christian; Burgos, Carlos F.; Elena Tarnok, Maria; Felipe Aguilar, Luis

Article ISI
NEUROBIOLOGY OF DISEASE  (2020)

Deltamethrin determination in natural water samples via photochemically-induced fluorescence coupled to third-order multivariate calibration

Veneciano, Rodrigo, I; Sonnia Parra, V; Quiroz, Waldo; Fuentes, Edwar; Aguilar, Luis F.; Bravo, Manuel A.

Article ISI
MICROCHEMICAL JOURNAL  (2020)

Systematic study of the fluorescent properties of cinnamaldehyde phenylhydrazone and its interactions with metals: Synthesis and photophysical evaluation

Aguilar, Luis F.; Bravo, Manuel A.

Article ISI
JOURNAL OF MOLECULAR STRUCTURE  (2020)

Toxic effects of the anticancer drug epirubicin in vitro assayed in human erythrocytes

Aguilar, Luis F.; Strzalka, Kazimierz

Article ISI
TOXICOLOGY IN VITRO  (2020)

An in vitro study of the protective effect of caffeic acid on human erythrocytes

Suwalsky, Mario; Aguilar, Luis F.; Strzalka, Kazimierz

Article ISI SCOPUS
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS  (2019)

In vitro antioxidant and antiproliferative effect of the extracts of Ephedra chilensis K Presl aerial parts

Soto, Mauricio; Godoy, Patricio; Aguilar, Luis F.

Article ISI SCOPUS
BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE  (2019)

In vitro effects of the antitumor drug miltefosine on human erythrocytes and molecular models of its membrane

Petit, Karla; Suwalsky, Mario; Colina, Jose R.; Aguilar, Luis F.; Strzalka, Kazimierz

Article ISI SCOPUS
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES  (2019)

Protective effect of epigallocatechin gallate on human erythrocytes

Suwalsky, Mario; Aguilar, Luis F.; Strzalka, Kazimierz

Article ISI SCOPUS
COLLOIDS AND SURFACES B-BIOINTERFACES  (2019)

The acetylcholinesterase (AChE) inhibitor and anti-Alzheimer drug donepezil interacts with human erythrocytes

Zambrano P.; Sepúlveda B.

Article ISI SCOPUS
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES  (2019)

Understanding the antimicrobial properties/activity of an 11-residue Lys homopeptide by alanine and proline scan

Álvarez, C. A.; Aguilar, L. F.; Marshall, S. H.

Article ISI SCOPUS
AMINO ACIDS  (2018)

EFFECT OF HYDRATION AND PACKING ORDER ON LARGE UNILAMELLAR VESICLE FUSION: THE ROLE OF CHOLESTEROL

FRANCISCO J. CUEVAS; CAROLINA A. VALLE; LUIS F. AGUILAR

Article ISI SCIELO SCOPUS
Journal of the Chilean Chemical Society  (2017)

Evaluation of cloud point extraction coupled with fluorescence spectroscopy and multivariate curve resolution-alternating least squares for tributyltin determination in sediment samples

Alarcón F; Bustamante, R; Quiroz W.

Article ISI SCOPUS
MICROCHEMICAL JOURNAL  (2016)

Inhibitory effect of short cationic homopeptides against Gram-negative bacteria

Aróstica M.; Marshall S.H.; Albericio, F.; Ojeda, C; Aguilar L.F.; Guzman F

Article ISI SCOPUS
AMINO ACIDS  (2016)

Pentavalent antimony uptake pathway through erythrocyte membranes: molecular and atomic fluorescence approaches

Barrera C.; López S.; Aguilar, L; Mercado L.; Bravo M.; Quiroz W.

Article ISI SCOPUS
ANALYTICAL AND BIOANALYTICAL CHEMISTRY  (2016)

Evaluation of cloud point extraction coupled with fluorescence spectroscopy and multivariate curve resolution-alternating least squares for Tributyltin determination in sediment samples

Francis Alarcón, Roxana Bustamante, Waldo Quiroz, Luis F. Aguilar, Manuel A. Bravo

Article
MICROCHEMICAL JOURNAL  (2015)

A novel application of nylon membranes for tributyltin determination in complex environmental samples by fluorescence spectroscopy and multivariate calibration

Olivieri, AC; Bardin, E; Quiroz W.

Article ISI SCOPUS
Chemometrics and Intelligent Laboratory Systems  (2015)

Inactivation of Escherichia coli in goat milk using pulsed ultraviolet light

Kasahara I.; Carrasco, V.; Aguilar, L

Article ISI SCOPUS
JOURNAL OF FOOD ENGINEERING  (2015)

Low concentrations of ethanol protect against synaptotoxicity induced by A beta in hippocampal neurons

Muñoz, G; Burgos, C. F.; Silva, V.; Aguilar, F.; Sama M.; Opazo C.; Aguayo, L. G.

Article ISI SCOPUS
NEUROBIOLOGY OF AGING  (2015)

Sb(V) Reactivity with Human Blood Components: Redox Effects

López S.; Aguilar, L; Mercado L.; Bravo M.; Quiroz W.

Article ISI SCOPUS
PLOS ONE  (2015)

Speciation analysis of organotin compounds in human urine by headspace solid-phase micro-extraction and gas chromatography with pulsed flame photometric detection

Valenzuela A.; Lespes, G; Quiroz W.

Article ISI SCOPUS
TALANTA  (2014)

Determination of tributyltin at parts-per-trillion levels in natural waters by second-order multivariate calibration and fluorescence spectroscopy

Bravo M.; Quiroz W.; Olivieri, AC

Article ISI SCOPUS
Microchemical Journal  (2013)

Effect of cholesterol content on the structural and dynamic membrane properties of DMPC/DSPC large unilamellar bilayers

Soto-Arriaza, MA; Olivares-Ortega, C; Quina, FH; Sotomayor, CP

Article ISI SCOPUS
Biochimica et Biophysica Acta - Biomembranes  (2013)

Sb(V) and Sb(III) distribution in human erythrocytes: Speciation methodology and the influence of temperature, time and anticoagulants

Quiroz W.; Aguilar, L; Barria, M.; Veneciano, J; Martinez, D.; Bravo M.; Mercado L.

Article ISI SCOPUS
Talanta  (2013)

Differential Dynamic and Structural Behavior of Lipid-Cholesterol Domains in Model Membranes

Aguilar L.F.; Sánchez S.

Article ISI SCOPUS
PLOS ONE  (2012)

Effects of an antimalarial quinazoline derivative on human erythrocytes and on cell membrane molecular models

Rojas-Aguirre Y.; Hernandez-Luis, F; Mendoza-Martinez C.; Aguilar L.F.; Villena, F; Castillo I.; Suwalsky, M

Article ISI SCOPUS
Biochimica et Biophysica Acta - Biomembranes  (2012)

Human erythrocytes and neuroblastoma cells are in vitro affected by sodium orthovanadate

Suwalsky, M; Fierro, P; Villena, F; Aguilar L.F.; Jemiola-Rzeminska, M; Strzalka, K; Gul-Hinc, S; Ronowska, A; Szutowicz, A

Article ISI SCOPUS
Biochimica et Biophysica Acta - Biomembranes  (2012)

Effects of phenylpropanolamine (PPA) on in vitro human erythrocyte membranes and molecular models

Suwalsky, M; Zambrano P.; Mennickent S.; Villena, F; Sotomayor, CP; Bolognin, S

Article ISI SCOPUS
Biochemical and Biophysical Research Communications  (2011)

Human erythrocytes and neuroblastoma cells are affected in vitro by Au(III) ions

Suwalsky, M; González R.; Villena, F; Sotomayor, CP; Bolognin, S; Zatta, P

Article ISI SCOPUS
Biochemical and Biophysical Research Communications  (2010)

Structural effects of Zn2+ on cell membranes and molecular models

Suwalsky, M; Novoa V; Villena, F; Sotomayor, CP; Ronowska, A; Szutowicz, A

Article ISI SCOPUS
JOURNAL OF INORGANIC BIOCHEMISTRY  (2009)

Development of a non-thermal accelerated pulsed UV photolysis assisted digestion method for fresh and dried food samples

Solís C.; Lagunas-Solar, MC; Perley, BP; Pina, C; Flocchini, RG

Article ISI
NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS  (2002)

A procedure for the joint evaluation of substrate partitioning and kinetic parameters for reactions catalyzed by enzymes in reverse micellar solutions: I. Hydrolysis of 2-naphthyl acetate catalyzed by lipase in sodium 1,4-bis(2-ethylhexyl) sulfosuccinate (AOT)/buffer/heptane

Abuin E.; Lissi E.

Article ISI SCOPUS
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS  (2001)

Modulation of pig kidney Na+/K+-ATPase activity by cholesterol: Role of hydration

Sotomayor, CP; Cuevas, FJ; Helms, MK; Jameson DM

Article ISI
BIOCHEMISTRY  (2000)

The Anticancer Drug Adriamycin Interacts with the Human Erythrocyte Membrane



Article
ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES  (1999)

Cu2+ ions interact with cell membranes

Suwalsky, M; Ungerer, B; Quevedo, L.; Aguilar, F.

Article
JOURNAL OF INORGANIC BIOCHEMISTRY  (1998)

Ethanol affects the function of a neurotransmitter receptor protein without altering the membrane lipid phase

Tapia, J.C.; Aguayo, L. G.; Aguilar L.F.

Article
EUROPEAN JOURNAL OF PHARMACOLOGY  (1998)

The organochlorine pesticide lindane interacts with the human erythrocyte membrane

Suwalsky, M; Rodri?guez, C; Villena, F; Aguilar, F.

Article
PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY  (1998)

Effect of polyunsaturated fatty acid deficiency on dipole relaxation in the membrane interface of rat liver microsomes

Garda H.A.; Bernasconi A.M.; Brenner R.R.; Aguilar, F.; Soto, M. A.

Article
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES  (1997)

Laurdan properties in glycosphingolipid-phospholipid mixtures: A comparative fluorescence and calorimetric study

Maggio, B; Fidelio G.D.; Aguilar, F.

Article
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES  (1997)

The organochlorine pesticide heptachlor disrupts the structure of model and cell membranes

Suwalsky, M; Benites, M; Villena, F; Aguilar, F.

Article
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES  (1997)

Interaction of 2,4-dichlorophenoxyacetic acid (2,4-D) with cell and model membranes

Suwalsky, M; Benites, M; Villena, F; Aguilar, F.

Article
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES  (1996)

Interaction of Zn 2+ Ions with Phospholipid Multilayers



Article
International Journal of Polymeric Materials  (1996)

Main phase transition depression by incorporation of alkanols in DPPC vesicles in the gel state: Influence of the solute topology



Article
Colloids and Surfaces A: Physicochemical and Engineering Aspects  (1996)

Influence of cholesterol on the lateral mobility of Na+/K-ATPase reconstituted on giant unilamelar vesicles

Carlos Sotomayor; Francisco Cuevas; Luis Aguilar; Marco Soto; Susana Sánchez

Article
Biophys J.  (0)

Structural effects of tetrachloroauric acid on cell membranes and molecular models

Mario Suwalsky; Raquel González; Fernando Villena; Luis F. Aguilar; Carlos P. Sotomayor; Silvia Bolognin; Paolo Zatta

Article
Coordination Chemistry Reviews  (0)

Patent (1)

SISTEMA PARA APLICAR LUZ LASER ULTRAVIOLETA PULSADA A ALIMENTOS LIQUIDOS PARA CONSEGUIR LA DESINFECCION DE LOS ALIMENTOS LIQUIDOS, EN DONDE EL SISTEMA COMPRENDE CONTROLES AUTOMATICOS DE LA DOSIS DE RADIACION ULTRAVIOLETA Y DEL CAUDAL DEL LIQUIDO

Kasahara, Ismael M.; Bronstein, Fredy H.; Herrera, Hector F.; Salinas, Ricardo A.

Patent
 (2013)

Proyecto (13)

Analytical developments for the evaluation of toxicity pathways of Sb(V) and Sb(III) in eukaryotic cells

FONDECYT (1150528)

Proyecto
2015-2017
Coinvestigador(a)

Study about the interaction between CdTe quantum dots (QDs) and free radicals. Quenching of QDs's luminescence as a potential application for designing of QDs-based luminescent probes for free radical sensor.

FONDECYT (1150775)

Proyecto
2015-2018
Coinvestigador(a)

INTERACTIONS OF CELL PENETRATING PEPTIDES WITH MODEL MEMBRANES=> ROLE OF THE LIPID PHASE PHYSICAL PROPERTIES.

FONDECYT (1140800)

Proyecto
2014-2017
Inv. Responsable

POLYPROLINE II ANTIMICROBIAL PEPTIDES. USING A SEQUENCE TEMPLATE AS A GUIDE TO ESTABLISH STRUCTURE-ACTIVITY RELATIONSHIP

FONDECYT (1140926)

Proyecto
2014-2017
Coinvestigador(a)

Development of an Analytical Methodology to Organotin Speciation Analysis in Human Samples by Using Multivariate Calibration and Fluorescence Spectroscopy

FONDECYT (1120541)

Proyecto
2012-2015
Coinvestigador(a)

Distribution and reactivity of Sb (V) and Sb (III) in human erythrocytes

FONDECYT (1120205)

Proyecto
2012-2015
Coinvestigador(a)

“Estudio de la Interacción de péptidos análogos al dominio N-terminal de SMAC/DIABLO con una proteína inhibidora de la apoptósis

Dirección de Investigación PUCV (DI 037.359/2011)

Proyecto
2011-2011
Inv. Principal

Pasteurización de vino mediante luz ultravioleta pulsada=> determinación del efecto de destrucción microbiana en las características químicas relevantes

Dirección de Investigación PUCV (DI 125.752/2010)

Proyecto
2010-2010
Inv. Principal

Aprovechamiento de Residuos Vitivinícolas para la Obtención de Antioxidantes Naturales

Programa de Cooperación Interuniversitaria e Investigación Científica de España (AECI Nº A/016164/08)

Proyecto
2008-2010
Investigador(a)

Dinámica de nanosegundos en Na,K-ATPasa=> rol de Dominios Lipídicos Segregados en su flexibilidad Conformacional y Función

FONDECYT (1070320)

Proyecto
2007-2010
Coinvestigador(a)

Desarrollo y Evaluación de una Tecnología no térmica para la Pasteurización de jugos Clarificados de Manzana

FONDEF (D01I1050)

Proyecto
2001-2005
Director(a)

Cinética de Reacciones Enzimáticas en Soluciones de Micelas y Vesículas Reversas

FONDECYT (3990008)

Proyecto
1999-2000
Inv. Principal

Influencia de las Propiedades de la fase Lipídica en la Función de Na,K-ATPasa

FONDECYT (2970023)

Proyecto
1997-1998
Inv. Principal

Review (1)

Structural effects of tetrachloroauric acid on cell membranes and molecular models

Suwalsky, M; González R.; Villena, F; Sotornayor, CP; Bolognin, S; Zatta, P

Review ISI SCOPUS
Coordination Chemistry Reviews  (2009)

1
Maria Gabriela Lobos

Professor Titular

Institute of Chemistry

UNIVERSIDAD DE VALPARAÍSO

Valparaiso, Chile

1
Sigrid Mennickent

PROFESOR ASOCIADO

UNIVERSIDAD DE CONCEPCIÓN

Concepción, Chile

1
David Contreras

Full professor

Analitycal and Inorganic Chemistry

UNIVERSIDAD DE CONCEPCION

Concepción, Chile

1
Mauricio Cuellar

UNIVERSIDAD DE VALPARAÍSO

Valparaíso, Chile

2
PATRICIO CARVAJAL

Profesor adjunto

PONTIFICIA UNIVERSIDAD CATOLICA DE VALPARAISO

Valparaiso, Chile

2
Marco Soto

Profesor Asociado

Química Física

Pontificia Universidad Católica de Chile

Santiago, Chile

2
Fanny Guzman

Investigador Senior

Núcleo de Biotecnología Curauma

Pontificia Universidad Católica de Valparaiso

Valparaiso, Chile

3
Manuel Bravo

Profesor Titular

Instituto de quimica

PONTIFICIA UNIVERSIDAD CATÓLICA DE VALPARAÍSO, FACULTAD DE CIENCIAS, INSTITUTO DE QUÍMICA

Valparaiso, Chile

1
Patricio Godoy

Director

Facultad de Medicina

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

1
Sergio Marshall

PROFESSOR

BIOLOGY INSTITUTE

PONTIFICIA UNIVERSIDAD CATÓLICA DE VALPARAÍSO

Valparaíso, Chile

1
Enrique Werner

Académico

Ciencias Básicas

UNIVERSIDAD DEL BIO-BIO

Chillán, Chile

1
Luis Aguayo

Full Professor

Department of Physiology

Universidad de Concepcion

Concepcion, Chile

1
Susana Sanchez

Assistant Professor

Polimeros

Universidad de Concepcion

Concepcion, Chile

4
Manuel Bravo

Pontificia Universidad Catolica de Valparaiso

Valparaiso, Chile

47
LUIS AGUILAR

PROFESOR ADJUNTO

FACULTAD DE CIENCIAS

PONTIFICIA UNIVERSIDAD CATOLICA DE VALPARAISO

VALPARAISO, Chile

2
Claudio Alvarez

Profesor Asistente y responsable de Laboratorio

Acuicultura

Universidad Católica del Norte

Coquimbo, Chile

4
Marco Mellado

Profesor / Investigador

Facultad de Medicina y Ciencias de la Salud

Universidad Central de Chile

Santiago, Chile

2
Carlos Burgos

Profesor Asistente

Fisiología

UNIVERSIDAD DE CONCEPCION

Concepción, Chile

2
Claudio Alvarez

Investigador Titular

Laboratorio FIGEMA

Centro de Estudios Avanzados en Zonas Aridas

Coquimbo, Chile

1
Vanessa Novoa

Investigador

Facultad de Educación y Humanidades

Universidad de Tarapacá

Concepción, Chile

1
JAIME MELLA

PROFESOR ADJUNTO

INSTITUTO DE QUIMICA Y BIOQUIMICA

UNIVERSIDAD DE VALPARAISO

VALPARAISO, Chile

1
Alejandro Madrid

Academico Asociado

Química

Universidad de Playa ancha

Valparaíso, Chile

2
LUIS MERCADO

Profesor Titular

Instituto de Biología

Pontificia Universidad Católica de Valparaíso

Valparaíso, Chile

8
Waldo Quiroz

Profesor Adjunto

Pontificia Universidad Católica de Valparaíso

Valparaíso, Chile

1
Ismael Kasahara

Docente

Escuela de Alimentos

Pontificia Universidad Católica de Valparaíso

Valparaíso, Chile

1
Carlos Jara

Profesor adjunto

Universidad de Valparaíso

Reñaca, Chile

1
VIVIANA SILVA

Investigadora Independiente

No afiliada

Villa alemana, Chile

3
José Colina

Docente

Ciencias Químicas

Universidad de Concepción

Concepción, Chile

3
Karla Petit

Tutor

Instituto CREAR

Universidad San Sebastian

Concepción, Chile

1
Andrés Díaz

Investigador Científico

Departamento de Ingeniería de Materiales

Universidad de Concepción

Concepción, Chile

1
José Pino

Jefe de Carrera Bioquímica

Ciencias

Universidad de Viña del Mar

Viña del Mar, Chile

1
María Tarnok

Profesor Agregado

Instituto de Química

Pontificia Universidad Católica de Valparaíso

Valparaíso, Chile

1
Rodrigo Sánchez

Profesor Part-time

Pontificia Universidad Católica de Valparaíso

Valparaíso, Chile

3
Pablo Zambrano

Postdoctoral Researcher

Cellular and Molecular Biophysics

Max Planck Institute for Biochemistry

Munich, Alemania

1
Benjamín Sepúlveda

Personal técnico

Química inorgánica

Universidad de Concepción

Concepcion, Chile

1
Francis Alarcón

Profesional

Nacional y de Referencia en Salud Ambiental

Instituto de Salud Pública de Chile

Santiago, Chile

1
Carolina Valle

Profesor

Química

Universidad Vina del Mar

VIÑA DEL MAR, Chile

1
Christian Peters

Postdoc

Max Planck Institute for Biological Intelligence

Martinsried, Alemania