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Daniela Andrea Toro Ascuy

Profesor Asistente

Universidad Autonoma de Chile

Santiago, Chile

Virología; Biologia Molecular ; Inmunología

DOCTORADO EN MICROBIOLOGIA, UNIVERSIDAD DE SANTIAGO DE CHILE. Chile, 2015

Profesor Instructor I Part Time

UNIVERSIDAD DE SANTIAGO DE CHILE

SANTIAGO, Chile

2013 - 2015
Profesor Asistente Full Time

UNIVERSIDAD AUTONOMA DE CHILE

ciencias de la salud

SANTIAGO, Chile

2019 - At present
Profesor Asistente Full Time

UNIVERSIDAD DE CHILE

de Ciencias

Santiago, Chile

2023 - At present

Profesor Instructor I

Universidad Iberoamericana de Ciencia y Tecnologia

Chile

2010 - 2011
Post-Doc Full Time

Universidad de Chile

SANTIAGO, Chile

2015 - 2018

2019 at present - Nicolas Badilla Zambrano, Biochemistry, Universidad de Concepción
2018 - Alvaro Thadani Acosta, Molecular Biotechnology Enginner. Universidad de Chile.
2018 - Alejandra Leyva Gutierrez, Molecular Biotechnology Enginner. Universidad de Chile.
2014 - Diego Paine Cabrera, Biochemistry, Universidad de Santiago de Chile.
2014 - Alvaro Santibañez Vargas, Biochemistry, Universidad de Santiago de Chile.
2013 - Carolina Tambley Zamorano, Biochemistry, Universidad de Santiago de Chile.

CONICYT Doctoral fellowship

COMISION NACIONAL DE INVESTIGACION CIENTIFICA Y TECNOLOGICA

Chile, 2011

CONICYT Doctoral fellowship


Comparison of the First and Second Wave of Infections by SARS-CoV-2: A Retrospective and Longitudinal Study From a Primary Health Care Center in Santiago of Chile Acuña-Castillo, C; Inostroza-Molina, A; Castro, SA; Molina-Cabrera, S; Leiva-Salcedo, E.; Riquelme, D; Luraschi, R; Barrera-Avalos, C; Vallejos-Vidal, E; Mella-Torres, A; Mella-Torres, A; Valdés, D; Torres, C; Maisey, K; Escobar, A; Reyes-Cerpa, S; Toro-Ascuy, D; Imarai, M; Reyes-Lopez, FE; Sandino, AM Article FRONTIERS IN PUBLIC HEALTH (2022)
Epitranscriptomic regulation of HIV-1 full-length RNA packaging Pereira-Montecinos, Camila; Toro-Ascuy, Daniela; Ananias-Saez, Catarina; Gaete-Argel, Aracelly; Rojas-Fuentes, Cecilia; Riquelme-Barrios, Sebastian; Rojas-Araya, Barbara; Garcia-de-Gracia, Francisco; Aguilera-Cortes, Paulina; Chnaiderman, Jonas; Acevedo, Monica L.; Valiente-Echeverria, Fernando; Soto-Rifo, Ricardo Article ISI NUCLEIC ACIDS RESEARCH (2022)
Factors Influencing the Acceptance of COVID-19 Vaccines in a Country with a High Vaccination Rate Toro-Ascuy, Daniela; Cifuentes-Munoz, Nicolás; Avaria, Andrea; Pereira-Montecinos, Camila; Cruzat, Gilena; Peralta-Arancibia, Katherine; Zorondo-Rodríguez, Francisco Article VACCINES (2022)
Overnutrition, Nasopharyngeal Pathogenic Bacteria and Proinflammatory Cytokines in Infants with Viral Lower Respiratory Tract Infections Arias-Bravo, Guisselle; Valderrama, Gustavo; Inostroza, Jaime; Tapia, Cecilia; Toro-Ascuy, Daniela; Ramilo, Octavio; Orellana, Paz; Cifuentes-Munoz, Nicolás; Zorondo-Rodriguez, Francisco; Mejías, Asunción; Fuenzalida, Loreto F. Article International Journal of Environmental Research and Public Health (2022)
CBP80/20-dependent translation initiation factor (CTIF) inhibits HIV-1 Gag synthesis by targeting the function of the viral protein Rev Garcia-de-Gracia, Francisco; Gaete-Argel, Aracelly; Riquelme-Barrios, Sebastian; Pereira-Montecinos, Camila; Rojas-Araya, Barbara; Aguilera, Paulina; Oyarzun-Arrau, Aaron; Rojas-Fuentes, Cecilia; Acevedo, Monica L.; Chnaiderman, Jonas; Valiente-Echeverria, Fernando; Toro-Ascuy, Daniela; Soto-Rifo, Ricardo Article ISI RNA BIOLOGY (2021)
The Landscape of IFN/ISG Signaling in HIV-1-Infected Macrophages and Its Possible Role in the HIV-1 Latency Rojas, Masyelly; Luz-Crawford, Patricia; Soto-Rifo, Ricardo; Reyes-Cerpa, Sebastian; Toro-Ascuy, Daniela Article ISI CELLS (2021)
Bacterial Synthesis of Ternary CdSAg Quantum Dots through Cation Exchange: Tuning the Composition and Properties of Biological Nanoparticles for Bioimaging and Photovoltaic Applications Órdenes-Aenishanslins, Nicolás; Anziani-Ostuni, Giovanna; Monrás, Juan Pablo; Tello, Alejandra; Bravo, Denisse; Toro-Ascuy, Daniela; Soto-Rifo, Ricardo; Prasad, Paras N.; Pérez-Donoso, José Manuel Article Microorganisms (2020)
Development of an Isavirus minigenome system to study the function of the pocket RNA-binding domain of the viral nucleoprotein (NP) in salmon cells Toro-Ascuy D.; SantibaÃ±ez A.; PeÃ±a V.; Beltran-Pavez C.; Cottet L.; Molina C.; Montoya M.; Sandoval N.; VÃ¡squez-MartÃnez Y.; Mascayano C.; Cortez-San MartÃn M. Article ISI SCOPUS JOURNAL OF FISH DISEASES (2020)
Non-Specific Antibodies Induce Lysosomal Activation in Atlantic Salmon Macrophages Infected by Piscirickettsia salmonis Perez-Stuardo, Diego; Espinoza, Allison; Tapia, Sebastian; Morales-Reyes, Jonathan; Barrientos, Claudio; Vallejos-Vidal, Eva; Sandino, Ana M.; Spencer, Eugenio; Toro-Ascuy, Daniela; Rivas-Pardo, J. Andres; Reyes-Lopez, Felipe E.; Reyes-Cerpa, Sebastian Article ISI FRONTIERS IN IMMUNOLOGY (2020)
A Rev–CBP80–eIF4AI complex drives Gag synthesis from the HIV-1 unspliced mRNA Toro-Ascuy, Daniela; Rojas-Araya, Bárbara; García-de-Gracia, Francisco; Rojas-Fuentes, Cecilia; Pereira-Montecinos, Camila; Gaete-Argel, Aracelly; Valiente-Echeverría, Fernando; Ohlmann, Théophile; Soto-Rifo, Ricardo Article ISI SCOPUS Nucleic Acids Research (2018)
Rescue of Infectious Salmon Anemia Virus (ISAV) from Cloned cDNA. Toro-Ascuy, Daniela; Martín, Marcelo Cortez-San Article Methods in molecular biology (Clifton, N.J.) (2017)
Avian Influenza Virus H5 Strain with North American and Eurasian Lineage Genes in an Antarctic Penguin. Barriga, Gonzalo P; Boric-Bargetto, Dusan; San Martin, Marcelo Cortez; Neira, Víctor; van Bakel, Harm; Thompsom, Michele; Tapia, Rodrigo; Toro-Ascuy, Daniela; Moreno, Lucila; Vasquez, Yesseny; Sallaberry, Michel; Torres-Pérez, Fernando; González-Acuña, Daniel; Medina, Rafael A Article Emerging infectious diseases (2016)
DEAD-box RNA helicase DDX3 connects CRM1-dependent nuclear export and translation of the HIV-1 unspliced mRNA through its N-terminal domain. Fröhlich, Alvaro; Rojas-Araya, Bárbara; Pereira-Montecinos, Camila; Dellarossa, Alessandra; Toro-Ascuy, Daniela; Prades-Pérez, Yara; García-de-Gracia, Francisco; Garcés-Alday, Andrea; Rubilar, Paulina S; Valiente-Echeverría, Fernando; Ohlmann, Théophile; Soto-Rifo, Ricardo Article Biochimica et biophysica acta (2016)
Interactions between the HIV-1 Unspliced mRNA and Host mRNA Decay Machineries. Toro-Ascuy, Daniela; Rojas-Araya, Bárbara; Valiente-Echeverría, Fernando; Soto-Rifo, Ricardo Article Viruses (2016)
Isolation and characterization of salmonid CD4+ T cells Maisey K, Montero R.; Corripio-Miyar Y., Toro-Ascuy D.; Valenzuela B., Reyes-Cerpa S.; María Sandino A., Zou J.; Wang, T.; Secombes C.J., Imarai Article Journal of Immunology (2016)
Predominant bacteria associated with black rockcod (Notothenia coriiceps, Richardson 1844) from King George Island, Antarctica Avendano-Herrera, R; Irgang, R; Poblete-Morales, M; Vasquez-Martinez, Y; Robles, C; Toro-Ascuy, D; Cortez-San Martin, M Article Bulletin of the European Association of Fish Pathologists (2016)
Development of a reverse genetic system for infectious salmon anemia virus=> rescue of recombinant fluorescent virus by using salmon internal transcribed spacer region 1 as a novel promoter. Toro-Ascuy, Daniela; Tambley, Carolina; Beltran, Carolina; Mascayano, Carolina; Sandoval, Nicolas; Olivares, Eduardo; Medina, Rafael A; Spencer, Eugenio; Cortez-San Martín, Marcelo Article Applied and environmental microbiology (2015)
Development of plaque assay for Chilean infectious salmon anaemia virus, application for virus purification and titration in salmon ASK cells. Castillo-Cerda, M T; Cottet, L; Toro-Ascuy, D; Spencer, E; Cortez-San Martín, M Article Journal of fish diseases (2014)
Induction of anti-inflammatory cytokine expression by IPNV in persistent infection Reyes-Cerpa S.; Reyes-Lopez F.; Toro-Ascuy D.; Montero R.; Maisey K.; Acuna-Castillo C.; Sunyer J.O.; Parra, D; Sandino A.M.; Imarai M. Article FISH & SHELLFISH IMMUNOLOGY (2014)
IPNV modulation of pro and anti-inflammatory cytokine expression in Atlantic salmon might help the establishment of infection and persistence. Reyes-Cerpa, Sebastián; Reyes-López, Felipe E; Toro-Ascuy, Daniela; Ibañez, Jorge; Maisey, Kevin; Sandino, Ana María; Imarai, Mónica Article Fish & shellfish immunology (2012)
Identification of CD3e, CD4, CD8b splice variants of Atlantic salmon Maisey, Kevin;; Toro-Ascuy, Daniela;; Montero, Ruth;; Reyes-López, Felipe; ; Imarai, Monica; Article Fish and Shellfish immunology (2011)


Rol de los ARNs no codificantes (ARNnc) en la respuesta inflamatoria inducida por la replicación del VIH-1 en las células inmunes del sistema nervioso central Toro-Ascuy, Daniela; Fuenzalida, Loreto F. Proyecto (2022)
Role of m6A on lncRNAs involved in neuroinflammation induced in microglia infected by HIV-1 Pereira-Montecinos, Camila Proyecto (2022)
Unraveling the epitranscriptomic control of the inflammatory response induced by HIV1 replication in the central nervous system Toro-Ascuy, Daniela Proyecto (2018)
A landscape of the HIV-1 full-length unspliced mRNA nuclear export and translation initiation complexes FONDECYT (3160091) Proyecto 2016-2018 Inv. Principal
“Plataforma para la generación y producción de ISAV recombinante mediante un sistema de genética reversa=> Servicio para la producción de antígeno Viral. VIU segunda etapa FONDEF (14E025) Proyecto 2015-2016 Director(a)
sub-proyecto. “Aislamiento, genotipificación y desarrollo de vacuna tipo VLP de virus exóticos mediante la expresión de proteína recombinantes en sistema Baculovirus/células de insecto.” Corporación de Fomento de la Producción (CORFO 13CTI-21527) Proyecto 2014-2015 Investigador(a)
“Plataforma para la generación y producción de ISAV recombinante mediante un sistema de genética reversa=> Servicio para la producción de antígeno Viral. VIU primera etapa FONDEF (140025) Proyecto 2014-2014 Director(a)
Estudio de la diversidad viral y bacteriana en aguas y especies de peces antárticos=> búsqueda de reservorios naturales de patógenos de salmónidos FONDECYT (RT_08D13) Proyecto 2013-2015 Personal técnico y/o de apoyo
Generation of recombinant infectious salmon anemia virus (isav) by reverse genetic. FONDECYT (11110212) Proyecto 2012-2014 Tesista


New Challenges of HIV-1 Infection: How HIV-1 Attacks and Resides in the Central Nervous System Rojas-Celis, V; Valiente-Echeverria, F; Soto-Rifo, R; Toro-Ascuy, D Review ISI CELLS (2019)