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Jaime Andrés Rivas Pardo

Profesor Asociado

Universidad Mayor

Santiago, Chile

Mechanobiology of bacterial adhesion Physiology and mechanics of sarcomeric proteins Mechanobiochemistry at the single molecule level Protein structure, relation between structure and function

Molecular Biology-Structural Biology-, UNIVERSIDAD DE CHILE. Chile, 2012
Biochemistry-Enzimology, UNIVERSIDAD DE SANTIAGO DE CHILE. Chile, 2005
Biochemist, UNIVERSIDAD DE SANTIAGO DE CHILE. Chile, 2004

Postdoctoral Researcher Full Time

COLUMBIA UNIVERSITY

New York, Estados Unidos

2012 - 2017
Associate Research Scientiest Full Time

COLUMBIA UNIVERSITY

New York, Estados Unidos

2017 - 2018
Investigador Asociado Full Time

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

2018 - 2019
Profesor Asistente Full Time

Universidad Mayor

Santiago, Chile

2019 - 2023
Profesor Asociado Full Time

UNIVERSIDAD MAYOR

Chile

2023 - At present

Technician Full Time

Universidad de Santiago de Chile

Santiago, Chile

2005 - 2007

Mejor Trabajo de Incorporación 2018

Sociedad Bioquímica y Biología Molecular

Chile, 2018

Mejor Trabajo Incorporación, reunión anual de la sociedad de Bioquímica y Biología Molecular 2018.
Best Poster Presentation

NEXOS USA Chile

Estados Unidos, 2016

Mejor presentación poster, reunión NEXOS US-Chile 2016 Philadelphia
Best Presentation

FASEB Science Research Conference

Chile, 2016

Mejor presentación, reunion FASEB Functional Disulfide Bonds in Health and Disease. Steamboat Springs, Colorado.


KLF17 is an important regulatory component of the transcriptomic response of Atlantic salmon macrophages to <i>Piscirickettsia salmonis</i> infection Perez-Stuardo, Diego; Frazao, Mateus; Ibaceta, Valentina; Brianson, Bernardo; Sanchez, Evelyn; Rivas-Pardo, J. Andres; Vallejos-Vidal, Eva; Reyes-Lopez, Felipe E.; Toro-Ascuy, Daniela; Vidal, Elena A.; Reyes-Cerpa, Sebastian Article ISI FRONTIERS IN IMMUNOLOGY (2023)
Phylogenomic analysis of the <i>Porphyromonas gingivalis-Porphyromonas gulae</i> duo: approaches to the origin of periodontitis Morales-Olavarria, Mauricio; Nunez-Belmar, Josefa; Gonzalez, Damariz; Vicencio, Emiliano; Rivas-Pardo, Jaime Andres; Cortez, Cristian; Cardenas, Juan P. Article ISI FRONTIERS IN MICROBIOLOGY (2023)
Anaerobic RSH-dependent tellurite reduction contributes to Escherichia coli tolerance against tellurite Munoz-Diaz, P.; Jimenez, K.; Luraschi, R.; Cornejo, F.; Figueroa, M.; Vera, C.; Rivas-Pardo, A.; Sandoval, J. M.; Vasquez, C.; Arenas, F. Article ISI SCIELO BIOLOGICAL RESEARCH (2022)
A HaloTag-TEV genetic cassette for mechanical phenotyping of proteins from tissues Rivas-Pardo, Jaime Andrés; Li, Yong; Mártonfalvi, Zsolt; Tapia-Rojo, Rafael; Unger, Andreas; Fernández-Trasancos, Ángel; Herrero-Galán, Elías; Velázquez-Carreras, Diana; Fernández, Julio M.; Linke, Wolfgang A.; Alegre-Cebollada, Jorge Article NATURE COMMUNICATIONS (2020)
Non-Specific Antibodies Induce Lysosomal Activation in Atlantic Salmon Macrophages Infected by Piscirickettsia salmonis Perez-Stuardo, Diego; Espinoza, Allison; Tapia, Sebastian; Morales-Reyes, Jonathan; Barrientos, Claudio; Vallejos-Vidal, Eva; Sandino, Ana M.; Spencer, Eugenio; Toro-Ascuy, Daniela; Rivas-Pardo, J. Andres; Reyes-Lopez, Felipe E.; Reyes-Cerpa, Sebastian Article ISI FRONTIERS IN IMMUNOLOGY (2020)
Single-Nucleotide Polymorphisms (SNP) Mining and Their Effect on the Tridimensional Protein Structure Prediction in a Set of Immunity-Related Expressed Sequence Tags (EST) in Atlantic Salmon (Salmo salar) Vallejos-Vidal E.; Reyes-Cerpa S.; Rivas-Pardo J.A.; Maisey K.; YÃ¡Ã±ez J.M.; Valenzuela H.; Cea P.A.; Castro-Fernandez V.; Tort L.; Sandino A.M.; Imarai M.; Reyes-LÃ³pez F.E. Article ISI SCOPUS FRONTIERS IN GENETICS (2020)
Understanding gold toxicity in aerobically-grown Escherichia coli Munoz-Villagran, C.; Contreras, F.; Cornejo, F.; Figueroa, M.; Valenzuela-Bezanilla, D.; Luraschi, R.; Reinoso, C.; Rivas-Pardo, J.; Vasquez, C.; Castro, M.; Arenas, F. Article ISI SCIELO BIOLOGICAL RESEARCH (2020)
The Mechanical Power of Titin Folding Eckels, Edward C.; Haldar, Shubhasis; Tapia-Rojo, Rafael; Rivas-Pardo, Jaime Andrés; Fernández, Julio M. Article CELL REPORTS (2019)
Molecular strategy for blocking isopeptide bond formation in nascent pilin proteins Rivas-Pardo, Jaime Andres; Badilla, Carmen L.; Tapia-Rojo, Rafael; Alonso-Caballero, Alvaro; Fernandez, Julio M. Article ISI PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
The power of the force: mechano-physiology of the giant titin Rivas-Pardo, Jaime Andrés Article Emerging Topics in Life Sciences (2018)
The Work of Titin Protein Folding as a Major Driver in Muscle Contraction Julius, D; Rivas-Pardo, Jamie Andres; Eckels, Edward C.; Fernandez, Julio M.; Tapia-Rojo, Rafael Article ISI ANNUAL REVIEW OF PHYSIOLOGY, VOL 80 (2018)
Mechanical Deformation Accelerates Protein Ageing Fernandez, Julio M.; Popa, Ionel; Valle-Orero, Jessica; Echelman, Daniel J.; Tapia-Rojo, Rafael; Haldar, Shubhasis; Rivas-Pardo, Jaime Andres Article ISI ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)
Multidomain proteins under force Valle-Orero, Jessica; Rivas-Pardo, Jaime Andres; Popa, Ionel Article ISI NANOTECHNOLOGY (2017)
Proteins Breaking Bad: A Free Energy Perspective Valle-Orero, Jessica; Tapia-Rojo, Rafael; Eckels, Edward C.; Rivas-Pardo, Jaime Andres; Popa, Ionel; Fernandez, Julio M. Article ISI JOURNAL OF PHYSICAL CHEMISTRY LETTERS (2017)
A HaloTag Anchored Ruler for Week-Long Studies of Protein Dynamics Popa, Ionel; Rivas-Pardo, Jaime Andres; Eckels, Edward C.; Echelman, Daniel J.; Badilla, Carmen L.; Valle-Orero, Jessica; Fernandez, Julio M. Article ISI JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2016)
Work Done by Titin Protein Folding Assists Muscle Contraction Fernandez, Julio M.; Kosuri, Pallav; Rivas-Pardo, Jaime Andres; Linke, Wolfgang A.; Popa, Ionel; Eckels, Edward C. Article ISI CELL REPORTS (2016)
Dissecting the functional roles of the conserved NXXE and HXE motifs of the ADP-dependent glucokinase from Thermococcus litoralis Abarca-Lagunas, MJ; Rivas-Pardo, JA; Ramirez-Sarmiento, CA; Guixe, V Article ISI SCOPUS FEBS Letters (2015)
Identifying Sequential Substrate Binding at the Single-Molecule Level by Enzyme Mechanical Stabilization Rivas-Pardo, JA; Alegre-Cebollada, J; Ramirez-Sarmiento, CA; Fernandez, JM; Guixe, V Article ISI SCOPUS ACS Nano (2015)
S-Glutathionylation of Cryptic Cysteines Enhances Titin Elasticity by Blocking Protein Folding Fernandez, Julio M.; Hamdani, Nazha; Alegre-Cebollada, Jorge; Warren, Chad M.; Giganti, David; Solaro, R. John; Rivas-Pardo, Jaime Andres; Linke, Wolfgang A.; Eckels, Edward; Kosuri, Pallav Article ISI CELL (2014)
Crystal Structure, SAXS and Kinetic Mechanism of Hyperthermophilic ADP-Dependent Glucokinase from Thermococcus litoralis Reveal a Conserved Mechanism for Catalysis Rivas-Pardo, JA; Herrera-Morande, A; Castro-Fernandez, V; Fernandez, FJ; Vega, MC; Guixe, V Article ISI SCOPUS PLOS ONE (2013)
Nanomechanics of HaloTag Tethers Popa, Ionel; Berkovich, Ronen; Alegre-Cebollada, Jorge; Badilla, Carmen L.; Rivas-Pardo, Jaime Andrés; Taniguchi, Yukinori; Kawakami, Masaru; Fernandez, Julio M. Article JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2013)
Catalytic and regulatory roles of divalent metal cations on the phosphoryl-transfer mechanism of ADP-dependent sugar kinases from hyperthermophilic archaea Merino F.; Rivas-Pardo, J.A.; Caniuguir, A; Garcia, I; Guixe, V Article ISI SCOPUS Biochimie (2012)
Direct observation of disulfide isomerization in a single protein Alegre-Cebollada, J; Kosuri, P; Rivas-Pardo, JA; Fernandez, JM Article ISI SCOPUS Nature Chemistry (2011)
Divalent metal cation requirements of phosphofructokinase-2 from E. coli. Evidence for a high affinity binding site for Mn2+ Rivas-Pardo, JA; Caniuguir, A; Wilson, CAM; Babul, J.; Guixe, V Article ISI SCOPUS Archives of Biochemistry and Biophysics (2011)
Site-directed mutagenesis study of the microenvironment characteristics of Lys(213) of Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase Yevenes A.; Espinoza, R.; Rivas-Pardo, JA; Villarreal, JM; Gonzalez-Nilo, FD; Cardemil, E Article ISI SCOPUS BIOCHIMIE (2006)


Interfering with the Folding of Group A Streptococcal pili 2 Proteins Contreras, Fernanda; Rivas-Pardo, Jaime Andrés; Proft, Thomas; Loh, Jacelyn M. S. BookSection NEISSERIA MENINGITIDIS (2020)
Real-time Detection of Thiol Chemistry in Single Proteins Eckels, Edward C.; Echelman, Daniel J.; Rivas-Pardo, Jaime Andrés; Fernandez, Julio M.; Feige, Matthias J. BookSection (2018)


MechanoPhysiology of Titin FONDECYT (11180705) Proyecto 2018-2021 Inv. Responsable
NANOMECHANICS OF BACTERIAL ADHESION NIH (GM116122) Proyecto 2015-2018 Postdoctorado
“Degradation of titin at the single molecular level” Columbia Global Center (1) Proyecto 2014-2015 Postdoctorado
High throughput single molecule AFM force-spectrometer NSF (NSF/DBI-1252857) Proyecto 2013-2016 Postdoctorado
SINGLE MOLECULE STUDIES OF TITIN ELASTICITY NIH (HL061228) Proyecto 2012-2018 Postdoctorado
EVOLUTION OF RIBOKINASE SUPERFAMILY ENZYMES=> STRUCTURE-FUNCTION RELATIONSHIPS THAT DETERMINE SUBSTRATE SPECIFICITY, METAL ASSISTED MECHANISM AND PROTEIN STABILITY. FONDECYT (1110137) Proyecto 2011-2015 Personal técnico y/o de apoyo
“Protein Domains Closure Triggered by Ligands and Transition State Analogs” Laboratório Nacional de Luz Síncrotron (LNLS), Campinas, Sao Paulo, Brazil. (D11A - SAXS1-9184) Proyecto 2010-2010 Coinvestigador(a)
“Effect of Ligands in the Protein Domain Closure Studied by SAXS Laboratório Nacional de Luz Síncrotron (LNLS), Campinas, Sao Paulo, Brazil. (D11A - SAXS1 - 9249) Proyecto 2009-2009 Coinvestigador(a)
FILOGENIA, MECANISMO CATALITICO Y ESPECIFICIDAD DE SUSTRATO EN ENZIMAS DE LA SUPERFAMILIA RIBOQUINASA. IMPLICACIONES PARA LA EVOLUCION DE LA SUPERFAMILIA. FONDECYT (1070111) Proyecto 2007-2011 Personal técnico y/o de apoyo
FILOGENIA, MECANISMO CATALITICO Y ESPECIFICIDAD DE SUSTRATO EN ENZIMAS DE LA SUPERFAMILIA RIBOQUINASA. IMPLICACIONES PARA LA EVOLUCION DE LA SUPERFAMILIA. FONDECYT (1070111) Proyecto 2007-2011 Tesista
ESTRUCTURA Y MECANISMO DE ACCION DE CARBOXIQUINASA FOSFOENOLPIRUVICA. FONDECYT (1030760) Proyecto 2003-2007 Personal técnico y/o de apoyo
ESTRUCTURA Y MECANISMO DE ACCION DE CARBOXIQUINASA FOSFOENOLPIRUVICA. FONDECYT (1030760) Proyecto 2003-2007 Tesista