Man

Roberto Pablo Javier Henzi Miranda

Profesor Asistente

Universidad Católica de Temuco

Temuco, Chile

Líneas de Investigación


Neurociencia; Células Madre/progenitores neurales; Patologías del neurodesarrollo

Educación

  •  Doctorado en Ciencias Veterinarias, UNIVERSIDAD AUSTRAL DE CHILE. Chile, 2016
  •  Médico Veterinario, UNIVERSIDAD CATOLICA DE TEMUCO. Chile, 2010

Experiencia Académica

  •   Profesor Asistente Full Time

    UNIVERSIDAD CATOLICA DE TEMUCO

    Recursos Naturales

    Temuco, Chile

    2023 - At present

  •   Profesor/Investigador Part Time

    UNIVERSIDAD DE LA FRONTERA

    Medicina

    Temuco, Chile

    2021 - 2022

  •   Postdoctoral Fellow Full Time

    UNIVERSIDAD DE LOS ANDES

    Medicina

    Chile

    2016 - 2018

  •   Postdoctoral Fellow Full Time

    UNIVERSIDAD DE LOS ANDES

    Medicina

    Santiago, Chile

    2019 - 2021

Experiencia Profesional

  •   Postdoctorado Full Time

    Universidad de los Andes

    Santiago, Chile

    2019 - 2021

  •   Profesor Asistente Full Time

    Universidad Católica de Temuco

    Temuco, Chile

    2023 - At present

  •   Lab Manager Part Time

    Universidad de los Andes

    Santiago, Chile

    2018 - 2021

Difusión y Transferencia


- Henzi R, Bustamante F, Mendez-Ruette, M, Wyneken U and Batiz, LF. 2021. The M105I mutation of alpha-SNAP leads to increased levels of pAMPK affecting the mitochondrial homeostasis and the balance between selfrenewal/proliferation and differentiation of neural stem/progenitor cells. 11th International meeting on AMPK. Evian, France.
- Méndez-Ruette, Anllely Fernández, Karina Cordero, Roberto Henzi, Federico Batiz, Alejandro RojasFernández, Ursula Wyneken. 2019. SUMOylation determines the protein cargo of astrocyte-derived small extracellular vesicles. XXXIII Annual Meeting of Chilean society for cell biology. Puerto Varas, Chile.
- Sebastian Illanes, Lorena Abarzua-Catalan, Roberto Henzi, Ursula Wyneken, Federico Luis Batiz and Roberto Romero. Maternal brain-to-fetal brain communication mediated by small extracellular vesicles: A role in prenatal stress. ISPD 23rd International Conference on Prenatal Diagnosis and Therapy, Singapore.
- Luarte A, Henzi R, Ramírez JP, Masalleras Matías, Villalobos I, Varas M, Wyneken U. 2017. Astrocyte-derived exosomes interact with neurons decreasing neuritic branching. XXX Annual Meeting of Chilean Society for cell biology. Puerto Varas, Chile.
- Henzi R, Vío K, Guerra M., Herrera C., McAllister P., Johanson C., Rodríguez EM. 2015. Grafting of neuralstem cells to repair
the ventricular disruption in hydrocephalic HTx rats. IV ISCT south and central américa regional meeting y III Congreso de Terapia Celular y
Medicina Regenerativa. Santiago, Chile.
- Roberto Henzi, Karin Vío, Montserrat Guerra, Pat McAllister, Conrad Johanson, Esteban M. Rodríguez. Grafting of healthy neural stem cells to repair the ventricular zone disruption in hydrocephalic Htx rats. 59th Annual Meeting Society of Research into hydrocephalus and spina bifida (SRHSB). Málaga, España.
- Roberto Henzi, M Clara Jara, Montserrat Guerra, Karin Vío, Sara Rodríguez, Marjorie Jara, Conrad Johanson, Pat McAllister, Esteban M. 2014. Neural stem cell graftted into the ventricle of HTx rats move to the disrupted ventricular zone. 58th Annual Meeting of Society of Research into Hydrocephalus and Spina Bifida. Upsala, Suecia.
- Esteban M. Rodríguez, Roberto Henzi, Marjorie Jara, Paula Salazar, M Clara Jara, Karin Vío, Montserrat Guerra, Sara Rodríguez, Eduardo Ortega, Jaime Jaque, Pat McAllister, Conrad Johanson. 2014. In search for cell therapy of foetal onset hydrocephalus. 58th Annual Meeting of Society of Research into Hydrocephalus and Spina Bifida. Upsala, Suecia.
- Roberto Henzi, Nicole Lichtin, Montserrat Guerra, Alexander Orttlof , Francisca Castillo, Karin Vío, Esteban M. Rodríguez. 2013. A cell junction pathology of neural stem cells leads to the disruption of the ventricular zone in the pallium of the hydrocephalic HTx rat. 57th Annual Meeting of Society of Research into Hydrocephalus and Spina Bifida. Cologne, Alemania.



 

Article (8)

Bulk serum extracellular vesicles from stressed mice show a distinct proteome and induce behavioral and molecular changes in naive mice
Alpha-SNAP (M105I) mutation promotes neuronal differentiation of neural stem/progenitor cells through overactivation of AMPK
Astrocyte-Derived Small Extracellular Vesicles Regulate Dendritic Complexity through miR-26a-5p Activity
Small Extracellular Vesicles in Rat Serum Contain Astrocyte-Derived Protein Biomarkers of Repetitive Stress
Neurospheres from neural stem/neural progenitor cells (NSPCs) of non-hydrocephalic HTx rats produce neurons, astrocytes and multiciliated ependyma: the cerebrospinal fluid of normal and hydrocephalic rats supports such a differentiation
Astrocytes at the hub of the stress response=> potential modulation of neurogenesis by miRNAs in astrocyte-derived exosomes.
The value of early and comprehensive diagnoses in a human fetus with hydrocephalus and progressive obliteration of the aqueduct of Sylvius: Case Report
Cell Junction Pathology of Neural Stem Cells Is Associated With Ventricular Zone Disruption, Hydrocephalus, and Abnormal Neurogenesis

Proyecto (4)

Efectos del estrés materno sobre el desarrollo neuronal en la progenie
“Exosomas liberados por células madre neurales y su posible efecto beneficioso para estimular la neurogénesis alterada de ratas sometidas a estrés crónico”
Novel Neurobiological Treatments for Hydrocephalus
DISRUPTION OF THE NEUROEPITHELIUM/EPENDYMA (VENTRICULAR ZONE) DURING DEVELOPMENT LEADS TO HYDROCEPHALUS, ABNORMAL BRAIN DEVELOPMENT AND IMPAIRED POSTNATAL NEUROGENESIS. STRATEGIES AIMED TO DIMINISH/REPAIR THE OUTCOMES OF VENTRICULAR ZONE DI

Review (1)

Astrocytes at the Hub of the Stress Response: Potential Modulation of Neurogenesis by miRNAs in Astrocyte-Derived Exosomes
5
Inge Wyneken

Full Professor

Medicina

UNIVERSIDAD DE LOS ANDES

Santiago, Chile

3
Maria Guerra

Profesor Asociado

INSTITUTO DE ANATOMÍA, HISTOLOGÍA Y PATOLOGÍA, FACULTAD DE MEDICINA, UNIVERSIDAD AUSTRAL DE CHILE

Universidad Austral de Chile

Valdivia , Chile

1
Alexander Ortloff

Académico

UNIVERIDAD CATÓLICA DE TEMUCO

Temuco, Chile

2
Luis Federico Batiz

Full Professor

Center for Biomedical Research and Innovation (CIIB)

Universidad de Los Andes

Santiago, Chile

2
MANUEL VARAS

Research Professor

UNIVERSIDAD SAN SEBASTIÁN

Santiago, Chile

1
Rodrigo Vergara

Investigador

Psicología

Universidad San Sebastián

Valdivia, Chile

1
Carlos Lafourcade

Profesor Asociado

UNIVERSIDAD DE LOS ANDES

Chile

8
Roberto Henzi

Profesor Asistente

Ciencias Veterinarias y Salud Pública

Universidad Católica de Temuco

Temuco, Chile

3
Alejandro Luarte

Profesor Investigador

Neurociencias

Universidad de Los Andes

santiago, Chile

1
Nicole Lichtin

Encargada genomica y genética de leguminosas de grano

Ciencia en Plantas

CGNA

Temuco, Chile

1
Rodrigo Herrera

Group Leader (staff member)

Combinatorial NeuroImaging Core Facility

Leibniz Institute for Neurobiology

Magdeburg, Alemania

2
César González

Profesor Asistente

Facultad de Medicina y Ciencias

Universidad San Sebastián

Puerto Montt, Chile

1
Fernando Hinostroza

Profesor part-time

Ciencias básicas

Universidad Católica del Maule

Talca, Chile

1
Ariel Caviedes

Postdoctorado

Escuela de psicología

Universidad Adolfo Ibánez

Santiago, Chile

1
Matías Pizarro

research assistant

Psicología

Latin American Brain Health Institute (BrainLat), Universidad Adolfo Ibáñez.

Santiago, Chile