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Alexander Fernández de la Torre

Profesor Asistente

Universidad de Concepción

Concepción, Chile

Síntesis asimétrica de productos naturales por reacciones multicomponentes y/o organocatalisadas.; Síntesis y evaluación biológica de derivados de péptidos y peptidomiméticos.; Aplicación de reacciones en flujo continuo para la síntesis de moléculas bioactivas.

LICENCIADO EN QUÍMICA, FACULTAD DE QUIMICA. Cuba, 2006
MAESTRIA EN QUIMICA, UNIVERSIDAD DE LA HABANA. Cuba, 2010
DOCTOR EN CIENCIAS, UNIVERSIDADE FEDERAL DE SAO CARLOS. Brasil, 2015
LICENCIADO EN QUÍMICA, UNIVERSIDAD DE LA HABANA. Cuba, 2006

Asistente Full Time

UNIVERSIDAD DE CONCEPCION

Ciencias Químicas

Concepción , Chile

2017 - At present

Profesor Instructor

UNIVERSIDAD DE LA HABANA, FACULTAD DE QUIMICA

Cuba

2006 - 2007
Profesor Instructor

SEDE UNIVERSITARIA MUNICIPAL DE CIENCIAS MEDICAS

Cuba

2007 - 2009
Profesor Asistente Full Time

Universidad de Concepción

Concepción, Chile

2017 - At present

PREMIO NACIONAL DE LA ACADEMIA DE CIENCIAS DE CUBA

UNIVERSIDAD DE LA HABANA

Cuba, 2016

Impacto de trabajo; “Aplicaciones sintéticas de las reacciones multicomponentes de cicloadición y órgano-catalíticas”
PREMIO UNIVERSIDAD DE LA HABANA

UNIVERSIDAD DE LA HABANA

Chile, 2016

Al mejor artículo en ciencias Naturales y Exactas; “Highly Stereoselective synthesis of natural-product-like hybrids by an Organocatalytic/Multicomponent reaction sequence”.
PREMIO UNIVERSIDAD DE LA HABANA, CUBA

UNIVERSIDAD DE LA HABANA

Chile, 2016

Al resultado que refleje el avance científico técnico de mayor transcendencia y originalidad.


Development of eco-friendly polyurethane foams based on Lesquerella fendleri (A. Grey) oil-based polyol Contreras, Jorge; Valdés, Oscar; Mirabal-Gallardo, Yaneris; de la Torre, Alexander F.; Navarrete, José; Lisperguer, Justo; Durán-Lara, Esteban F.; Santos, Leonardo S.; Nachtigall, Fabiane M.; Cabrera-Barjas, Gustavo; Abril, Diana Article ISI SCOPUS European Polymer Journal (2020)
Facile Synthesis, Spectral (IR, Mass, UV-Vis, NMR), Linear and Nonlinear Investigation of the Novel Phosphonate Compounds: A Combined Experimental and Simulation Study Khalid M.; Ali A.; De la Torre A.F.; Marrugo K.P.; Concepcion O.; Kamal G.M.; Muhammad S.; Al-Sehemi A.G. Article ISI SCOPUS CHEMISTRYSELECT (2020)
One-pot organocatalytic/multicomponent approach for the preparation of novel enantioenriched non-natural selenium-based peptoids and peptide-peptoid conjugates de la Torre, AF; Ali, A; Galetto, FZ; Braga, AL; Delgado, JAC; Paixao, MW Article ISI MOLECULAR DIVERSITY (2020)
Spectroscopic and DFT/TDDFT insights of the novel phosphonate imine compounds Ali A.; Khalid M.; Marrugo K.P.; Kamal G.M.; Saleem M.; Khan M.U.; ConcepciÃ³n O.; de la Torre A.F. Article ISI SCOPUS (2020)
Synthesis and Cytotoxic Analysis of Novel Myrtenyl Grafted Pseudo-Peptides Revealed Potential Candidates for Anticancer Therapy Concepcion, Odette; Belmar, Julio; de la Torre, Alexander F.; Muniz, Francisco M.; Pertino, MarianoW.; Alarcon, Barbara; Ormazabal, Valeska; Nova-Lamperti, Estefania; Zuniga, Felipe A.; Jimenez, Claudio A. Article ISI MOLECULES (2020)
A stereoselective sequential organocascade and multicomponent approach for the preparation of tetrahydropyridines and chimeric derivatives Echemendia, R; da Silva, GP; Kawamura, MY; de la Torre, AF; Correa, AG; Ferreira, MAB; Rivera, DG; Paixao, MW Article ISI SCOPUS CHEMICAL COMMUNICATIONS (2019)
One-pot organocatalytic/multicomponent approach for the preparation of novel enantioenriched non-natural selenium-based peptoids and peptidepeptoid conjugates de la Torre A.F.; Ali A.; Galetto F.Z.; Braga A.L.; Delgado J.A.C.; PaixÃ£o M.W. Article SCOPUS Molecular Diversity (2019)
Rationalizing the stability and interactions of 2,4-diamino-5-(4-chlorophenyl)-6-ethylpyrimidin-1-ium 2-hydroxy-3,5-dinitrobenzoate salt Tahir, Muhammad Nawaz; Ashfaq, Muhammad; de la Torre, Alexander E.; Caballero, Julio; Hernandez-Rodriguez, Erix W.; Ali, Akbar Article ISI SCOPUS JOURNAL OF MOLECULAR STRUCTURE (2019)
Synthesis of diN-Substituted Glycyl-Phenylalanine Derivatives by Using Ugi Four Component Reaction and Their Potential as Acetylcholinesterase Inhibitors Prent-Penaloza, L; de la Torre, AF; Velazquez-Libera, JL; Gutierrez, M; Caballero, J Article ISI SCOPUS MOLECULES (2019)
Ugi reaction-derived prolyl peptide catalysts grafted on the renewable polymer polyfurfuryl alcohol for applications in heterogeneous enamine catalysis de la Torre, Alexander F; Scatena, Gabriel S; Valdés, Oscar; Rivera, Daniel G; Paixão, Márcio W Article ISI SCOPUS BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY (2019)
An efficient cyclization of lapachol to new benzo[h]chromene hybrid compounds: a stepwise vs. one-pot esterification-click (CuAAC) study de La Torre A.F.; Ali A.; Westermann B.; Schmeda-Hirschmann G.; Walter Pertino M. Article ISI SCOPUS (2018)
Preparation of renewable bio-polyols from two species of Colliguaja for Rigid polyurethane foams Abril-MilÃ¡n D.; ValdÃ©s O.; Mirabal-Gallardo Y.; de La Torre A.F. ; Bustamante C.; Contreras J. Article ISI SCOPUS Materials (2018)
Multicomponent Synthesis of Cyclic Depsipeptide Mimics by Ugi Reaction Including Cyclic Hemiacetals Derived from Asymmetric Organocatalysis de la Torre, Alexander F.; Rivera, Daniel G.; Concepcion, Odette; Echemendia, Radell; Correa, Arlene G.; Paixao, Marcio W. Article ISI Journal of Organic Chemistry (2016)
Highly Stereoselective Synthesis of Natural-Product-Like Hybrids by an Organocatalytic/Multicomponent Reaction Sequence Echemendia, Radell; de La Torre, Alexander F.; Monteiro, Julia L.; Pila, Michel; Correa, Arlene G.; Westermann, Bernhard; Rivera, Daniel G.; Paixao, Marcio W. Article ISI ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2015)
Multicomponent Approach to Silica-Grafted Peptide Catalysts: A 3D Continuous-Flow Organocatalytic System with On-line Monitoring of Conversion and Stereoselectivity Scatena, Gabriel S.; de la Torre, Alexander F.; Cass, Quezia B.; Rivera, Daniel G.; Paixao, Marcio W. Article ISI CHEMCATCHEM (2014)
Polyethylene glycol (PEG) as a reusable solvent medium for an asymmetric organocatalytic Michael addition. Application to the synthesis of bioactive compounds Feu, Karla S.; de la Torre, Alexander F.; Silva, Sandrina; de Moraes Junior, Marco A. F.; Correa, Arlene G.; Paixao, Marcio W. Article ISI GREEN CHEMISTRY (2014)
Basic-functionalized recyclable ionic liquid catalyst: A solvent-free approach for Michael addition of 1,3-dicarbonyl compounds to nitroalkenes under ultrasound irradiation Narayanaperumal, Senthil; da Silva, Rodrigo Cesar; Feu, Karla Santos; de la Torre, Alexander Fernandez; Correa, Arlene G.; Paixao, Marcio Weber Article ISI ULTRASONICS SONOCHEMISTRY (2013)
Multicomponent Combinatorial Development and Conformational Analysis of Prolyl Peptide-Peptoid Hybrid Catalysts: Application in the Direct Asymmetric Michael Addition de la Torre, Alexander F.; Rivera, Daniel G.; Ferreira, Marco A. B.; Correa, Arlene G.; Paixao, Marcio W. Article ISI Journal of Organic Chemistry (2013)
Estudio fitoquímico preliminar y actividad fungicida de corteza de maytenus urquiolae mory (celastraceae) de la torre, Alexander F; Nogueiras, Clara; Romeu, Carlos; Palacios, Jorge Roberto; Naranjo, Enoc; Marbot, Rolando; Urquiola, Armando Article Fitosanidad (2010)


DISEÑO, SÍNTESIS POR REACCIONES MULTICOMPONENTES BASADAS EN ISONITRILOS Y EVALUACIÓN BIOLÓGICA DE UNA NUEVA LIBRERÍA DE COMPUESTOS FOSFONO-PEPTIDOMIMÉTICOS COMO INHIBIDORES DE LA ENZIMA PSEUDOMONA ELASTASA (LASB) FONDECYT (3170003) Proyecto 2017-2020 Inv. Responsable
SYNTHESIS AND BIOLOGICAL ACTIVITY OF NOVEL NAPHTHOQUINONE-TRIAZOLE DERIVATIVES PREPARED BY CLICK CHEMISTRY FONDECYT (1161092) Proyecto 2016-2019 Personal técnico y/o de apoyo
Síntese de Bio-Moléculas Contendo Selênio e Nitrogênio=> Compostos Potencialmente Bioativos e/ou Ligantes Quirais Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) (403846/2014-5 -) Proyecto 2015-2016 Inv. Principal