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MARIANO WALTER PERTINO

Profesor conferenciante

UNIVERSIDAD DE TALCA, INSTITUTO DE QUÍMICA DE RECURSOS NATURALES

TALCA, Chile

Líneas de Investigación


Biological activity of naturally occurring and synthetic compounds; Action mechanisms of bioactive compounds in human cell cultures; Cytotoxicity and antiproliferative activity in human cell cultures; Natural Products Chemistry; Biological activity of  naturally occurring compounds and semisynthetic derivatives; Ethnopharmacology; Structure-activity relationships in bioactive compounds; Semisynthesis; Natural products

Educación

  •  DOCTOR EN CIENCIAS, UNIVERSIDAD DE TALCA. Chile, 2006
  •  LICENCIADO EN QUÍMICA, UNIVERSIDAD NACIONAL DEL SUR. Argentina, 2002

Experiencia Académica

  •   Profesor conferenciante Full Time

    Universidad de Talca

    Instituto de Química de Recursos Naturales

    Talca, Chile

    2011 - At present

Experiencia Profesional

  •   Profesor conferenciante Full Time

    Universidad de Talca

    Talca, Chile

    2011 - At present


 

Article (29)

Isolation, Gastroprotective Effects and Untargeted Metabolomics Analysis of Lycium Minutifolium J. Remy (Solanaceae)
Synthesis and Cytotoxic Analysis of Novel Myrtenyl Grafted Pseudo-Peptides Revealed Potential Candidates for Anticancer Therapy
Synthesis, trypanocidal and anti-Leishmania activity of new triazole-lapachol and norlapachol hybrids
Inhibition of key enzymes in the inflammatory pathway by hybrid molecules of terpenes and synthetic drugs=> In vitro and in silico studies
An efficient cyclization of lapachol to new benzo[h]chromene hybrid compounds=> a stepwise vs. one-pot esterification-click (CuAAC) study
Synthesis, Antiviral and Cytotoxic Activity of Novel Terpenyl Hybrid Molecules Prepared by Click Chemistry
Antiprotozoal Activity of Triazole Derivatives of Dehydroabietic Acid and Oleanolic Acid
Natural and semisynthetic diterpenoids with antiviral and immunomodulatory activities block the ERK signaling pathway
Synthesis, antiproliferative and antifungal activities of 1,2,3-triazole-substituted carnosic Acid and carnosol derivatives.
Topical Anti-inflammatory Activity of New Hybrid Molecules of Terpenes and Synthetic Drugs.
Gastroprotective Mechanisms of Action of Semisynthetic Carnosic Acid Derivatives in Human Cells
Synthesis and antiproliferative activity of some novel triazole derivatives from dehydroabietic acid.
1,2,3-triazole-substituted oleanolic Acid derivatives: synthesis and antiproliferative activity.
Dimeric labdane diterpenes: synthesis and antiproliferative effects.
Diterpenylquinone hybrids: synthesis and assessment of gastroprotective mechanisms of action in human cells.
Absolute Configuration and H-1 NMR Characterization of Rosmaridiphenol Diacetate
New Gastroprotective Labdeneamides from (4S, 9R, 10R) Methyl 18-carboxy-labda-8,13(E)-diene-15-oate
Potential Gastroprotective Effect of Novel Cyperenoic Acid/Quinone Derivatives in Human Cell Cultures
Gastroprotective Effect and Cytotoxicity of Carnosic Acid Derivatives
Synthesis and pharmacological activity of diterpenylnaphthoquinone derivatives.
Gastroprotective effect of carnosic acid gamma-lactone derivatives.
Synthesis, gastroprotective effect and cytotoxicity of new amino acid diterpene monoamides and diamides.
The corrected structure of rosmaridiphenol, a bioactive diterpene from Rosmarinus officinalis.
Antiproliferative Activity of the Diterpenes Jatrophone and Jatropholone and Their Derivatives
A new antifungal and antiprotozoal depside from the Andean lichen Protousnea poeppigii
Biotransformation of jatrophone by Aspergillus niger ATCC 16404
Gastroprotective effect and cytotoxicity of semisynthetic jatropholone derivatives
Gastroprotective effect and cytotoxicity of terpenes from the Paraguayan crude drug yagua rova" (Jatropha isabelli)"
Gastroprotective activity and cytotoxic effect of cyperenoic acid derivatives

Proyecto (4)

DISEÑO, SÍNTESIS Y EVALUACIÓN ANTI-CANCERÍGENA DE NUEVOS HÍBRIDOS DERIVADOS DEL MONOTERPENO MIRTENAL (MIR).
SYNTHESIS AND BIOLOGICAL ACTIVITY OF NOVEL NAPHTHOQUINONE-TRIAZOLE DERIVATIVES PREPARED BY CLICK CHEMISTRY
NOVEL HYBRID TERPENE-NAPHTHOQUINONE GASTROPROTECTIVE COMPOUNDS=> SYNTHESIS AND ASSESSMENT OF ACTION MECHANISMS USING HUMAN CELL CULTURE MODELS.
SYNTHESIS OF CYTOTOXIC TERPENES=> A CLICK CHEMISTRY APPROACH
15
MARIANO PERTINO

Profesor conferenciante

UNIVERSIDAD DE TALCA, INSTITUTO DE QUÍMICA DE RECURSOS NATURALES

TALCA, Chile

2
Guillermo Schmeda

Profesor Titular

UNIVERSIDAD DE TALCA

Talca, Chile

1
LEONARDO SILVA

PROFESOR TITULAR

UNIVERSIDAD DE TALCA

TALCA, Chile

1
Veronica Olate

INVESTIGADOR ASISTENTE

Departamento de Investigaciones Interdisciplinarias

Universidad de Talca

TALCA, Chile

1
Marcelo Muñoz

Profesor Auxiliar

Instituto de Ciencias Químicas

Universidad Austral de Chile

Valdivia, Chile

1
Daniel Droguett

Profesor Conferenciante

Estomatología

Universidad de Talca

Talca, Chile