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Francisco Espinoza Villegas

Profesor Asistente

Universidad de los Andes

Santiago, Chile

- Biomarcadores en fluido salival para la evaluación de la actividad y progresión de la Artritis Reumatoide - AR Temprana (ERA) - Terapia regenerativa / celular para la Osteoartritis de rodilla - Terapia celular en Lupus Eritematoso sistemico

Médico Cirujano, Universidad de los Andes. Chile, 2006
Especialista en Medicina Interna, Universidad de los Andes. Chile, 2010
Subespecialista en Reumatología, Université de Montpellier. Francia, 2010

Profesor Asistente Full Time

Universidad de los Andes

Medicina

Santiago, Chile

2010 - At present

Profesor Asistente Full Time

Universidad de los Andes

Santiago, Chile

2010 - At present
Research Fellowship Full Time

University of California San Diego (UCSD), RAI Division, School of Medicine

San Diego, Estados Unidos

2015 - 2015
Director Unidad de Artritis Reumatoide Temprana (UART) Part Time

CRS Peñalolen

Santiago, Chile

2015 - At present
Mèdico Staff Full Time

Clinica Universidad de los Andes

Santiago, Chile

2015 - At present
Jefe Servicio de Medicina Full Time

Clinica Universidad de los Andes

Santiago, Chile

2020 - At present

Premio Antonio Reginato

SOCIEDAD CHILENA DE REUMATOLOGIA

Chile, 2017

Premio al Mejor trabajo científico del congreso chileno de reumatología 2017, titulado: "Terapia Celular Alogènica basada en células mesenquimales de cordón umbilical en osteoartritis de rodilla: Ensayo fase I/II, controlado, doble ciego"


Soluble neuropilin-1 in gingival crevicular fluid is associated with rheumatoid arthritis: An exploratory case-control study Prieto, Diego; Gonzalez, Camila; Weber, Laura; Realini, Ornella; Pino-Lagos, Karina; Bendek, Maria José; Retamal, Ignacio; Beltrán, Víctor; Riedemann, Juan Pablo; Espinoza, Francisco; Chaparro, Alejandra Article Journal of Oral Biology and Craniofacial Research (2021)
Mesenchymal Stem Cells Improve Rheumatoid Arthritis Progression by Controlling Memory T Cell Response Luque-Campos, Noymar; Contreras-Lopez, Rafael A.; Jose Paredes-Martinez, Maria; Jose Torres, Maria; Bahraoui, Sarah; Wei, Mingxing; Espinoza, Francisco; Djouad, Farida; Javier Elizondo-Vega, Roberto; Luz-Crawford, Patricia Article ISI SCOPUS FRONTIERS IN IMMUNOLOGY (2019)
Umbilical Cord-Derived Mesenchymal Stromal Cells (MSCs) for Knee Osteoarthritis: Repeated MSC Dosing Is Superior to a Single MSC Dose and to Hyaluronic Acid in a Controlled Randomized Phase I/II Trial Matas, Jose; Orrego, Mario; Amenabar, Diego; Infante, Catalina; Tapia-Limonchi, Rafael; Ignacia Cadiz, Maria; Alcayaga-Miranda, Francisca; Gonzalez, Paz L.; Muse, Emilio; Khoury, Maroun; Figueroa, Fernando E.; Espinoza, Francisco Article ISI SCOPUS STEM CELLS TRANSLATIONAL MEDICINE (2019)
[Implementation of an early rheumatoid athritis unit for the early recognition and treatment of the disease]. Espinoza, Francisco; Monckeberg, Gustavo; Hassi, Isabel; Queirolo, Alejandra; Chicao, Fernando; Sandoval, Ximena; Jorquera, Evelyn; Badilla, Alejandro Article Revista medica de Chile (2018)
Implementation of an early rheumatoid arthritis unit for the early recognition and treatment of the disease Espinoza F.; monckeberg, g; Hassi, I; Queirolo, A; Chicao, F; Sandoval, X; Jorquera, E; Badilla, A Article REVISTA MEDICA DE CHILE (2018)
Injection of Adipose-Derived Stromal Cells in the Knee of Patients with Severe Osteoarthritis has a Systemic Effect and Promotes an Anti-Inflammatory Phenotype of Circulating Immune Cells. Pers, Yves-Marie; Quentin, Julie; Feirreira, Rosanna; Espinoza, Francisco; Abdellaoui, Naoill; Erkilic, Nejla; Cren, Maïlys; Dufourcq-Lopez, Emilie; Pullig, Oliver; Nöth, Ulrich; Jorgensen, Christian; Louis-Plence, Pascale Article Theranostics (2018)
Secreted alpha-Klotho maintains cartilage tissue homeostasis by repressing NOS2 and ZIP8-MMP13 catabolic axis Chuchana, Paul; Mausset-Bonnefont, Anne-Laure; Mathieu, Marc; Espinoza, Francisco; Teigell, Marisa; Toupet, Karine; Ripoll, Chantal; Djouad, Farida; Noel, Daniele; Jorgensen, Christian; Brondello, Jean-Marc Article ISI AGING-US (2018)
Biologic Disease-modifying Antirheumatic Drug (bDMARD)-induced Neutropenia: A Registry from a Retrospective Cohort of Patients with Rheumatic Diseases Treated with 3 Classes of Intravenous bDMARD Espinoza F.; Le Blay P.; Combe B. Article ISI SCOPUS JOURNAL OF RHEUMATOLOGY (2017)
Handgrip strength measured by a dynamometer connected to a smartphone: a new applied health technology solution for the self-assessment of rheumatoid arthritis disease activity Pers, Yves-Marie; Lieu, Sylvain; Espinoza, Francisco; Munro, Janet; Coulon, Denis; Jorgensen, Christian; Le Blay, Pierre Article ISI RHEUMATOLOGY (2016)
Efficacy of Tocilizumab in the treatment of Eosinophilic fasciitis: Report of one case Pers, Yves-Marie; Jorgensen, Christian; Espinoza, Francisco Article ISI JOINT BONE SPINE (2015)
p16(INK4a) and its regulator miR-24 link senescence and chondrocyte terminal differentiation-associated matrix remodeling in osteoarthritis Philipot, Didier; Guerit, David; Platano, Daniela; Chuchana, Paul; Olivotto, Eleonora; Espinoza, Francisco; Dorandeu, Anne; Pers, Yves-Marie; Piette, Jacques; Borzi, Rosa Maria; Jorgensen, Christian; Noel, Daniele; Brondello, Jean-Marc Article ISI ARTHRITIS RESEARCH & THERAPY (2014)
Embarazos exitosos en hemodiálisis crónica: experiencia de un único centro Francisco Espinoza; Romina Romeo; Marcela Ursu; Augusto Tapia; Antonio Vukusich Article SCIELO SCOPUS REVISTA MEDICA DE CHILE (2013)
Pregnancy during dialysis. Experience in six patients Espinoza F.; Romeo, R; Ursu, M; Tapia, A; Vukusich A. Article ISI REVISTA MEDICA DE CHILE (2013)
Assesment of arterial damage by noninvasive peripheral arterial tonometry in non-diabetic hemodialysis patients Espinoza F.; Kunstmann, S; Urzúa, A; Michea, L.; Marusic, ET; Vukusich A. Article ISI REVISTA MEDICA DE CHILE (2012)
Daño arterial asociado a la enfermedad renal crónica: evaluación mediante técnicas de laboratorio no invasivo en pacientes hemodializados Espinoza F.; Kunstmann, S; Urzúa, A; Michea, L.; Marusic E.T.; Vukusich A. Article SCIELO SCOPUS REVISTA MEDICA DE CHILE (2012)
Na+-K+-2Cl(-) cotransporter is implicated in gender differences in the response of the rat aorta to phenylephrine Palacios J.; Espinoza F.; Munita C.; Cifuentes F.; Michea, L. Article ISI SCOPUS BRITISH JOURNAL OF PHARMACOLOGY (2006)


A Proposal for Assessing Systemic Lupus Erythematosus Activity By a Multimodal Instrument That Includes Clinical Variables, Physician Assessment and Modification of Treatment Espinoza F.; Kalunian, K Abstract ISI ARTHRITIS & RHEUMATOLOGY (2015)
REPRESSION OF WOLF-HISCHHORN SYNDROME CANDIDATE-1 (WHSC1) CONTRIBUTES TO OSTEOARTHRITIS-INDUCING CARTILAGE LOSS OF FUNCTIONS Espinoza F.; Pers, YM; Chuchana P.; Brondello, JM; Jorgensen C. Abstract ISI ANNALS OF THE RHEUMATIC DISEASES (2014)
Self-Assessment Tool of Rheumatoid Arthritis Disease Activity: Handgrip Strength Measured By a Smartphone Connected to a Dynamometer Espinoza F.; Pers, YM; LeBlay, P; Jorgensen C. Abstract ISI ARTHRITIS & RHEUMATOLOGY (2014)


Púrpura trombocitopénico trombótico con respuesta exitosa a vincristina Espinoza, Francisco; LEAL, JOSÉ LUIS; Arenas, Guillermo CaseReport SCIELO REVISTA MEDICA DE CHILE (2007)


Método de obtención de una composición que contiene una población específica de células mesenquimales de cordón umbilical y sus usos Khoury, Maroun; Figueroa, Fernando; Espinoza, Francisco; Bartolucci, Jorge; Castro, Diego; Gonzalez, Paz Patent PCT, solicitud de patente


Association between chronic periodontitis and rheumatoid arthritis. A systematic review Schilin Wen; Víctor Beltrán; Alejandra Chaparro; Francisco Espinoza; Juan Pablo Riedemann Review ISI SCIELO SCOPUS REVISTA MEDICA DE CHILE (2019)
Overview and perspectives of mesenchymal stem cell therapy in intensive care medicine Francisco Espinoza; Felipe Aliaga; Patricia Luz Crawford Review ISI SCIELO SCOPUS REVISTA MEDICA DE CHILE (2016)
Remission-induction therapies for early rheumatoid arthritis: evidence to date and clinical implications Espinoza, F; Fabre, S; Pers, YM Review ISI SCOPUS Therapeutic Advances in Musculoskeletal Disease (2016)