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Clemente Javier Palacios Díez

Académico

Universidad Arturo Prat

Iquique, Chile

Líneas de Investigación


Efecto vascular y cardiovascular de extractos de plantas medicinales y sus metabolitos. Estudio de los mecanismos fisiológicos involucrados y rol del estrés oxidativo.

Educación

  •  Ciencias Ph.D., Universidad de Navarra. España, 2001
  •  Bioquímico, UNIVERSIDAD COMPLUTENSE DE MADRID. España, 1987

Experiencia Académica

  •   académico e investigador Part Time

    UNIVERSIDAD DE LOS ANDES

    Medicina

    Santiago, Chile

    1997 - 2004

  •   académico e investigador Part Time

    UNIVERSIDAD CATOLICA DEL NORTE

    Ciencias

    Antofagasta, Chile

    2004 - 2008

  •   Profesor Asociado Full Time

    Universidad del Mar

    Iquique, Chile

    2009 - 2012

  •   Profesor Titular Full Time

    UNIVERSIDAD ARTURO PRAT

    Facultad Ciencias de la Salud

    Iquique, Chile

    2013 - At present

Experiencia Profesional

  •   Académico Full Time

    Universidad Arturo Prat

    IQUIQUE, Chile

    2013 - At present


 

Article (31)

A hydroalcoholic extract of Senecio nutans SCh. Bip (Asteraceae); its effects on cardiac function and chemical characterization
Alterations of the Oestrous Cycle and Increase in the Blood Pressure in Normotensive Female Rats by Continuous Exposure to Light
Chemical Fingerprinting, Aorta Endothelium Relaxation Effect, and Enzymatic Inhibition of Canelo (Drimys winteri J. R. Forst. & G. Forst, (D.C) A. Gray, Family Winteraceae) Fruits
UHPLC-MS Phenolic Fingerprinting, Aorta Endothelium Relaxation Effect, Antioxidant, and Enzyme Inhibition Activities of Azara dentata Ruiz & Pav Berries
Artocarpus Altilis (Breadfruit) could Reverse Myocardial Infarction Through the Normalization of the Oxygen Haemoglobin Dissociation Curve
Lepidium meyenii Walp (red maca) Supplementation Prevents Acrylamide-Induced Oxidative Stress and Liver Toxicity in Rats: Phytochemical Composition by UHPLC-ESI-MS/MS
Novel Oxime Synthesized from a Natural Product of Senecio nutans SCh. Bip. (Asteraceae) Enhances Vascular Relaxation in Rats by an Endothelium-Independent Mechanism
Phenolic Fingerprinting and Bioactivity Profiling of Extracts and Isolated Compounds from Gypothamnium pinifolium Phil.
High-Performance Thin-Layer Chromatography for Rutin, Chlorogenic Acid, Caffeic Acid, Ursolic Acid, and Stigmasterol Analysis in Periploca aphylla Extracts
Impact of the Potential Antitumor Agent 2-(4-Hydroxyphenyl) Amino-1,4-Naphthoquinone (Q7) on Vasomotion Is Mediated by the Vascular Endothelium, But Not Vascular Smooth Muscle Cell Metabolism
Maca extracts and estrogen replacement therapy in ovariectomized rats exposed at high altitude
Blood pressure-reducing activity of Gongronema latifolium Benth. (Apocynaeceae) and the identification of its main phytochemicals by UHPLC Q-Orbitrap mass spectrometry
Chemical Fingerprinting, Isolation and Characterization of Polyphenol Compounds fromHeliotropium taltalense(Phil.) IM Johnst and Its Endothelium-Dependent Vascular Relaxation Effect in Rat Aorta
Fast Isolation of Flavonoids from the Endemic Species Nolana ramosissima IM Johnst and Its Endothelium-Independent Relaxation Effect in Rat Aorta
Hypotensive and antihypertensive effects of an aqueous extract from Guinep fruit (Melicoccus bijugatus Jacq) in rats
Metabolomic Profiling of Mango (Mangifera indica Linn) Leaf Extract and Its Intestinal Protective Effect and Antioxidant Activity in Different Biological Models
Protective effects of apocynin against cadmium toxicity and serum parameters; evidence of a cardio-protective influence
Polyphenolic Composition and Hypotensive Effects of Parastrephia quadrangularis (Meyen) Cabrera in Rat
8-Oxo-9-Dihydromakomakine Isolated from Aristotelia chilensis Induces Vasodilation in Rat Aorta: Role of the Extracellular Calcium Influx
Ascorbate Attenuates Oxidative Stress and Increased Blood Pressure Induced by 2-(4-Hydroxyphenyl) Amino-1,4-naphthoquinone in Rats
Vasodilator and hypotensive effects of pure compounds and hydroalcoholic extract of Xenophyllum poposum (Phil) V.A Funk (Compositae) on rats
Aqueous extract from leaf of Artocarpus altilis provides cardio-protection from isoproterenol induced myocardial damage in rats: Negative chronotropic and inotropic effects
Hydroalcoholic extract and pure compounds from Senecio nutans Sch Bip (Compositae) induce vasodilation in rat aorta through endothelium-dependent and independent mechanisms
Hypotensive and antihypertensive effects of a hydroalcoholic extract from Senecio nutans Sch Bip. (Compositae) in mice: Chronotropic and negative inotropic effect, a nifedipine-like action
Modulatory Effect of 2-(4-Hydroxyphenyl)amino-1,4-naphthoquinone on Endothelial Vasodilation in Rat Aorta
Synchronization in the Heart Rate and the Vasomotion in Rat Aorta: Effect of Arsenic Trioxide
Effect of phenylephrine and endothelium on vasomotion in rat aorta involves potassium uptake
Exposure to Low Level of Arsenic and Lead in Drinking Water from Antofagasta City Induces Gender Differences in Glucose Homeostasis in Rats
Chronic Exposure to Arsenic in Tap Water Reduces Acetylcholine-induced Relaxation in the Aorta and Increases Oxidative Stress in Female Rats
Na+-K+-2Cl(-) cotransporter is implicated in gender differences in the response of the rat aorta to phenylephrine
Estradiol-induced expression of Na+-K+-ATPase catalytic isoforms in rat arteries: gender differences in activity mediated by nitric oxide donors

BookSection (1)

The Role of NADP(H) Oxidase Inhibition and Its Implications in Cardiovascular Disease Management Using Natural Plant Products

Review (1)

Oxidant-induced disruption of vascular K+ channel function: Implications for diabetic vasculopathy
1
Gareth Owen

Profesor Titular

Fisiologia

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

3
Mario Chiong

Profesor

Departamento de Bioquímica y Biología Molecular

Universidad de Chile

Santiago, Chile

33
Clemente Palacios

Académico

Química y Farmacia

Universidad Arturo Prat

Iquique, Chile

2
Jose Luis Vega

Profesor Asociado

Biomedico

Universidad de Antofagasta

Antofagasta, Chile

1
Elen Quispe

Académico

Facultad de Ciencias de la Salud

Universidad Arturo Prat

IQUIQUE, Chile

2
Julio Benites

Profesor Titular

Química y Farmacia

Universidad Arturo Prat

Iquique, Chile

2
Luis Michea

PROFESOR ASOCIADO

PROGRAMA FISIOLOGIA Y BIOFISICA

UNIVERSIDAD DE CHILE

Santiago, Chile

1
LUIS SOBREVIA

Professor

Division of Obstetrics and Gynaecology

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

SANTIAGO, Chile

1
Jovan Kuzmicic

Profesor Asistente

Departamento Salud

Universidad de Los Lagos

Osorno, Chile

1
Juan Sandoval

Profesor Asistente

UNIVERSIDAD ARTURO PRAT

Iquique, Chile

14
Adrian Paredes

Academico

Química

UNIVERSIDAD DE ANTOFAGASTA

Antofagasta, Chile

1
Javier Romero

Profesor Asistente

Departamento de Química Orgánica y Fisicoquímica

Universidad de Chile

Santiago, Chile

1
Carlos Lafourcade

Profesor Asociado

UNIVERSIDAD DE LOS ANDES

Chile

1
Pedro Buc

Profesor titular

Quimica y Farmacia

Universidad Arturo Prat

Iquique, Chile

2
Marcelo Catalan

Profesor Asociado

Facultad de Medicina

Universidad Austral de Chile

Valdivia, Chile

1
CLAUDIO PARRA

Profesor Asistente

Química Orgánica

Universidad de Concepción

Concepción, Chile

9
MARIO SIMIRGIOTIS

full professor

Facultad de Ciencias

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

1
Cristian Paz

Académico

Ciencias Químicas

Universidad de La Frontera

Temuco, Chile

1
Cristina Quispe

ACADEMICO

FACULTAD DE CIENCIAS DE LA SALUD

UNIVERSIDAD ARTURO PRAT

IQUIQUE, Chile

1
Felipe Salas

Académico

Química y Farmacia

Universidad Arturo Prat

Iquique, Chile

1
Francisco Espinoza

Profesor Asistente

Medicina Interna

Universidad de los Andes

Santiago, Chile

2
Jorge Borquez

Académico

Química

Universidad de Antofagasta

Antofagasta, Chile

1
Ignacio Norambuena

Postdoctorado

Universidad de Chile

Santiago, Chile

1
Iván Barría

Investigador Post doctoral

Centro Interdisciplinario de Neurociencia de Valparaíso

Valparaíso, Chile

4
Ruth Barrientos

Profesora Asistente

Química y Farmacia

Universidad San Sebastián

Puerto Montt, Chile