Man

Jose Luis Eduardo Vega Pizarro

Profesor Asociado

Universidad de Antofagasta

Antofagasta, Chile

Líneas de Investigación


My line of research is focused on understanding the role of gap junction proteins in parasitic diseases caused by protozoa of global importance with an emphasis on endemic diseases in Latin America such as Chagas disease.

Educación

  •  Tecnólogo Médico, UNIVERSIDAD DE ANTOFAGASTA. Chile, 2004
  •  Magister en Ciencias Biológicas mención Ciencias Fisiológicas, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2008
  •  Doctor en Ciencias Biológicas mención Ciencias Fisiológicas, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2010

Experiencia Académica

  •   Profesor Asociado Full Time

    UNIVERSIDAD DE ANTOFAGASTA

    Facultad Ciencias de la Salud

    Antofagasta, Chile

    2010 - At present

  •   Visiting research Full Time

    UNIVERSITY OF BRITISH COLUMBIA

    Faculty of Medicine

    Vancouver, Canada

    2012 - 2013

  •   postdoctorante Full Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Ciencias biologicas

    Chile

    2011 - 2012

Experiencia Profesional

  •   tecnologo medico Full Time

    Clinica Davila

    Santiago, Chile

    2003 - 2003

Formación de Capital Humano


MENTOR OF GRADUATE THESIS
1. Ivan Barria. Ph.D. Ciencias Biológicas, Universidad de Antofagasta, Chile. (2019)
2. Juan Güiza. Ph.D. Ciencias Biológicas, Universidad de Antofagasta, Chile (2020, currently in his last year of thesis)

MENTOR OF GRADUATE THESIS
1. Paula Ceardi Universidad de Antofagasta, Chile. (2020, currently in his last year of thesis)
2. Constanza Aravena Universidad de Antofagasta, Chile. (2020, currently in his last year of thesis)
3. Anibal Garcia, Universidad de Antofagasta, Chile. (2019)
4. Sergio Ossandon, Universidad de Antofagasta, Chile. (2019)
5. Nicolas Morales, Universidad de Antofagasta, Chile. (2019)
6. Mayerline Narvaez, Universidad de Antofagasta, Chile. (2018)
7. Constansa Cortes, Universidad de Antofagasta, Chile. (2018)
8. Siomara Vargas, Universidad de Antofagasta, Chile. (2018)
9. Silvestre Claudio, Universidad de Antofagasta, Chile. (2015)
10. Moraga Claudio, Universidad de Antofagasta, Chile. (2015)
11. Lagos David, Universidad de Antofagasta, Chile. (2015)
12. Moreno Daniela, Universidad de Antofagasta, Chile. (2010)
13. Pizarro Nicol, Universidad de Antofagasta, Chile. (2010)


Difusión y Transferencia


1. School fair organizer: Feria cientifica colegio San Jose, Octubre 2019, Antofagasta.
2. Workshop school organizer: Quimica de plantas del desierto, Escuela Basica Rural San Antonio De Padua, Ollagüe.
3. School scientific advisor:
- Escuela D-136, Antofagasta.
- Escuela E-67, Antofagasta.
- Liceo Bicentenario Agropecuario Likan Antai, San Pedro de Atacama.
- Colegio Inglés San José, Antofagasta.
4. Participation in "1000 científicos, 1000 aulas":
- 2018, Evidencias científicas de los efectos del consumo de marihuana dictada en NEW HEAVEN HIGH SCHOOL, Antofagasta.
- 2018, Evidencias científicas de los efectos del Yoga dicatada en THE ANTOFAGASTA BAPTIST COLLEGE, Antofagasta.
- 2018, Evidencias científicas de los efectos del consumo de marihuana dictada en COLEGIO BAUTISTA LOIS HART, Antofagasta.


Premios y Distinciones

  •   Hrvastka Skola Distinguished Ex-Alumni

    Hrvatska Skola

    Chile, 2010

    Recognition for alumni of the college who stand out in their profession.

  •   Workshop Travel Award

    Fundación Universitaria San Pablo CEU

    España, 2009

    Workshop Travel Award grande by the Fundación Universitaria San Pablo CEU, Madrid, Spain.

  •   New investigador travel award

    Canadian Institute of Health Research

    Canada, 2007

    Travel Award granted by Canadian Institute of Health Research, Canada.


 

Article (19)

Unnexins: Homologs of innexin proteins in Trypanosomatidae parasites

Guiza, J; Garcia, A.; Arriagada, J; Gutíerrez, C; Gonzalez, J; Marquez-Miranda, V; Alegria-Arcos M.; Duarte, Y; Rojas M.; Gonzalez-Nilo, F; Sáez, JC; Vega, JL

Article
JOURNAL OF CELLULAR PHYSIOLOGY  (2022)

A physiologic rise in cytoplasmic calcium ion signal increases pannexin1 channel activity via a C-terminus

Lopez, X; Palacios-Prado, N; Guiza, J; Escamilla, R; Fernández P.; Vega, JL; Rojas M.; Marquez-Miranda, V; Chamorro, E.; Cardenas, AM; Maldifassi, MC; Martinez, AD; Duarte, Y; Gonzalez-Nilo, F; Sáez JC

Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA  (2021)

Anti-parasitic drugs modulate the non-selective channels formed by connexins or pannexins

Guiza, J; Arriagada, J; Rodriguez, L; Gutierrez, C; Duarte, Y; Sáez, JC; Vega, JL

Article
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE  (2021)

Chitosan coating of BaTiO3@ZnO:Yb heterostructures: synthesis and properties

Fuentes, S.; Leon, J.; Vega, J. L.; Zenteno, S.

Article ISI
JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY  (2020)

Ascorbate Attenuates Oxidative Stress and Increased Blood Pressure Induced by 2-(4-Hydroxyphenyl) Amino-1,4-naphthoquinone in Rats

Palacios, Javier; Miguel Fonseca, Jose; Ayavire, Fernando; Salas, Felipe; Ortiz, Mirko; Marcelo Sandoval, Juan; Benites, Julio; Nwokocha, Chukwuemeka R.; Zavala, Ewaldo; Paredes, Adrian; Barria, Ivan; Luis Vega, Jose; Cifuentes, Fredi

Article ISI SCOPUS
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY  (2018)

Innexins: Expression, Regulation, and Functions.

Guiza, J; Barria, I; Sáez JC; Vega, JL

Article
FRONTIERS IN PHYSIOLOGY  (2018)

Trypanosoma cruzi Infection Induces Pannexin-1 Channel Opening in Cardiac Myocytes

Barria, Ivan; Guiza, Juan; Cifuentes, Fredi; Zamorano, Pedro; Saez, Juan C; Gonzalez, Jorge; Vega, Jose L.

Article ISI SCOPUS
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE  (2018)

Decreased cruzipain and gp85/trans-sialidase family protein expression contributes to loss of Trypanosoma cruzi trypomastigote virulence

San Francisco J, Barría I, Gutiérrez B, Neira I, Muñoz C, Sagua H, Araya JE, Andrade JC, Zailberger A, Catalán A, Remonsellez F, Vega JL, González J.

Article ISI SCOPUS
MICROBES AND INFECTION  (2017)

Regulation of gap junction channels and hemichannels by phosphorylation

Pogoda, K; Kameritsch, P; Retamal, MA; Vega, JL

Article ISI SCOPUS
BMC CELL BIOLOGY  (2016)

Pannexin channels mediate the acquisition of myogenic commitment in C2C12 reserve cells promoted by P2 receptor activation

Riquelme, Manuel A.; Cea, Luis A.; Vega, José L.; Puebla, Carlos; Vargas, Aníbal A.; Shoji, Kenji F.; Subiabre, Mario; Sáez, Juan C.

Article
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY  (2015)

Gap Junction Intercellular Communication Mediated by Connexin43 in Astrocytes Is Essential for Their Resistance to Oxidative Stress

Le H.T.; Sin W.C.; Lozinsky, S; Bechberger, J; Vega, J. L.; Guo X.Q.; Sáez, J.C.; Naus C.C.

Article ISI
JOURNAL OF BIOLOGICAL CHEMISTRY  (2014)

Mutations of Cx43 that affect B cell spreading in response to BCR signaling

Falk, L; Dang-Lawson, M; Vega, JL; Pournia, F; Choi, K; Jang, C; Naus, CC; Matsuuchi, L

Article ISI SCOPUS
BIOLOGY OPEN  (2014)

Cerebral ischemic injury is enhanced in a model of oculodentodigital dysplasia

Kozoriz MG, Lai S; Vega JL, Sáez JC; Sin WC, Bechberger JF

Article
Neuropharmacology  (2013)

Cerebral ischemic injury is enhanced in a model of oculodentodigital dysplasia.

Kozoriz M.G.; Lai S.; Vega, JL; Sáez JC; Sin, WC; Bechberger, J; Naus, C

Article
NEUROPHARMACOLOGY  (2013)

Effect of phenylephrine and endothelium on vasomotion in rat aorta involves potassium uptake

Palacios J.; Vega, JL; Paredes A.; Cifuentes F.

Article ISI SCOPUS
Journal of Physiological Sciences  (2013)

The ATP required for potentiation of skeletal muscle contraction is released via pannexin hemichannels

Riquelme MA, Cea LA; Vega JL, Boric MP; Monyer H, Bennett MV; Frank M, Willecke K

Article
Neuropharmacology  (2013)

Equilibrative nucleoside transporters in fetal endothelial dysfunction in diabetes mellitus and hyperglycaemia.

Westermeier, Francisco; Puebla, Carlos; Vega, José Luis; Farías, Marcelo; Escudero, Carlos; Casanello, Paola; Sobrevia, Luis

Article
Current vascular pharmacology  (2009)

TGF-beta 1 inhibits expression and activity of hENT1 in a nitric oxide-dependent manner in human umbilical vein endothelium

Vega, JL; Puebla, C; Vasquez R.; Farias M.; Alarcon J.; Pastor-Anglada, M; Krause, B; Casanello, P; Sobrevia L.

Article ISI SCOPUS
CARDIOVASCULAR RESEARCH  (2009)

D-Glucose stimulation of L-arginine transport and nitric oxicle synthesis results from activation of mitogen-activated protein kinases p42/44 and smad2 requiring functional type II TGF-beta receptors in human umbilical vein endothelium

Vaquez, R; Farias M.; Vega, JL; Martin, RS; Vecchiola, A; Casanello, P; Sobrevia L.

Article ISI SCOPUS
JOURNAL OF CELLULAR PHYSIOLOGY  (2007)

BookSection (3)

Possible Role of Gap Junction Channels and Non-Junctional Channels in the Infection Caused by Trypanosoma cruzi

Vega, JL; Juyumaya C; Rodríguez L.; Guiza, J; Gutierrez C.; Barria, I; Sáez JC

BookSection
 (2019)

Involvement of gap junction proteins in infectious diseases caused by parasites

Vega, JL; Barria, I; Guiza, J; Gonzalez, J; Sáez JC

BookSection
 (2017)

Virulence factors and immune evasion in Trypanosoma cruzi

Gonzalez, J; Gutierrez B.; Vega, JL; Araya J.

BookSection
 (2017)

Proyecto (3)

Adaptations in polyextreme environments: from the molecule to humans

Dorador C.; Vega, JL

Proyecto
 (2017)

Role of cardiac hemichannels in Trypanosoma cruzi infection

Vega, JL

Proyecto Fondecyt Initiation
 (2013)

Regulation of connexin-43 hemichannels properties by PKC, PKA and MAP kinase

Vega, JL

Proyecto Fondecyt Postdoctoral
 (2012)

Review (4)

Innexins: Expression, Regulation, and Functions

Guiza, J; Barria, I; Saez, JC; Vega, JL

Review ISI SCOPUS
FRONTIERS IN PHYSIOLOGY  (2018)

Role of Gap Junctions and Hemichannels in Parasitic Infections

Vega, JL; Subiabre, M; Figueroa F.; Schalper, KA; Osorio, L; Gonzalez, J; Sáez JC

Review ISI SCOPUS
BioMed Research International  (2013)

Connexin- and Pannexin-Based Channels in Normal Skeletal Muscles and Their Possible Role in Muscle Atrophy

Cea L.A.; Riquelme, M. A.; Cisterna B.A.; Puebla, C; Vega, J. L.; Rovegno M.; Sáez, J.C.

Review ISI SCOPUS
Journal of Membrane Biology  (2012)

Modulation of gap junction channels and hemichannels by growth factors

Schalper K.A.; Riquelme, M. A.; Branes M.C.; Martinez A.D.; Vega, J. L.; Berthoud V.M.; Bennett, M. V. L.; Sáez, J.C.

Review ISI SCOPUS
Molecular BioSystems  (2012)

26
Jose Luis Vega

Profesor Asociado

Biomedico

Universidad de Antofagasta

Antofagasta, Chile

7
Juan Saez

Professor

Instituto de Neurociencias

Universidad de Valparaiso

Valparaíso, Chile

4
Juan Sáez

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

4
Marcelo Farias

Assistant Professor

Division of Obstetrics and Gynecology

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE, DEPARTAMENTO DE OBSTETRICIA

Santiago, Chile

4
Iván Barría

Investigador Post doctoral

Centro Interdisciplinario de Neurociencia de Valparaíso

Valparaíso, Chile

3
Adrian Paredes

Academico

Química

UNIVERSIDAD DE ANTOFAGASTA

Antofagasta, Chile

2
Paola Casanello

Profesor Asociado

División de Obstetricia y Ginecología

Pontificia Universidad Católica de Chile

Santiago, Chile

2
Carlos Puebla

Assistant Professor

Universidad de O'Higgins

Santiago, Chile

2
Clemente Palacios

Académico

Química y Farmacia

Universidad Arturo Prat

Iquique, Chile

2
LUIS SOBREVIA

Professor

Division of Obstetrics and Gynaecology

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

SANTIAGO, Chile

2
Carlos Puebla

Profesor Asistente

Universidad de O'Higgins

Rancagua, Chile

1
Alejandro Catalán

Academico Jornada Completa

Tecnología Médica

Universidad de Antofagasta

Antofagasta, Chile

1
Luis Cea

Profesor programa teaching

Instituto de Ciencias Biomédicas

Universidad Autónoma de Chile

Santiago, Chile

1
PEDRO ZAMORANO

Profesor Asociado

Depto Biomédico

Universidad de Antofagasta

Antofagasta, Chile

1
FRANCISCO REMONSELLEZ

Professor

Ingenieria Química

UNIVERSIDAD CATÓLICA DEL NORTE

Antofagasta, Chile

1
Christian Muñoz

Profesor Asociado

Tecnología Médica

Universidad de Antofagasta

Antofagasta, Chile

1
Jorge Araya

Profesor Asociado

Departamento de Tecnología Médica

Universidad de Antofagasta

Antofagasta, Chile

1
Julio Benites

Profesor Titular

Química y Farmacia

Universidad Arturo Prat

Iquique, Chile

1
Mario Subiabre

1
Bessy Gutiérrez

PROFESORA

TECNOLOGÍA MÉDICA

Universidad de Antofagasta

Antofagasta, Chile

1
Jorge Gonzalez

Profesor Titular

Departamento de Tecnología Médica

UNIVERSIDAD DE ANTOFAGASTA

Antofagasta, Chile

1
Juan Sandoval

Profesor Asistente

UNIVERSIDAD ARTURO PRAT

Iquique, Chile

1
Sandra Fuentes

Docente

Ciencias Farmacéuticas

UNIVERSIDAD CTÓLICA DEL NORTE

Antofagasta, Chile

1
Agustin Martinez

Profesor Titular

Instituto de Neurociencia

UNIVERSIDAD DE VALPARAÍSO, CENTRO INTERDISCIPLINARIO DE NEUROCIENCIAS DE VALPARAÍSO

Valparaíso, Chile

1
Rody San Martín

Professor

Sciences Faculty

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

1
Bernardo Krause

Associate Professor

Insituto de Ciencias de la Salud

Universidad de O'Higgins

Rancagua, Chile

1
Julio Alarcón

Docente

Ciencias Básicas

UNIVERSIDAD DEL BÍO-BÍO

Chillan, Chile

1
Felipe Salas

Académico

Química y Farmacia

Universidad Arturo Prat

Iquique, Chile

1
Andrea Vecchiola

Profesor Asistente

Endocrinologia

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
IVAN NEIRA

Académico

Tecnología Médica

Universidad de Antofagasta

Antofagasta, Chile