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Paola Cecilia Casanello Toledo

Profesor Asociado

Pontificia Universidad Católica de Chile

Santiago, Chile

Programación cardiometabólica e inmune del feto asociado a la trayectoria de crecimiento fetal, hipoxia, obesidad materna y condiciones nutricionales de la madre.

Ciencias Fisiológicas, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2007
Ciencias Fisiológicas, UNIVERSIDAD DE CONCEPCION. Chile, 2003
Matrona, UNIVERSIDAD DE CONCEPCION. Chile, 1996
Perinatología, UNIVERSIDAD DE CONCEPCION. Chile, 2000

Profesor Asociado Full Time

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Medicina

Santiago, Chile

2014 - At present
Profesor Asociado Full Time

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Medicina

Santiago, Chile

2016 - At present
Instructor Full Time

UNIVERSIDAD DE CONCEPCION

Medicina

Concepción, Chile

1998 - 2001
Profesor Titular Full Time

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Medicina

Santiago, Chile

2022 - At present

Instructor Escuela de Medicina Part Time

Universidad de Concepción

Concepción, Chile

1998 - 2001
Profesor Asistente Escuela de Medicina Full Time

Universidad de Concepción

Concepción, Chile

2002 - 2003
Research Fellow Welcome Trust Full Time

Universidad de Chile

Santiago, Chile

2004 - 2005
Instructor Escuela de Medicina Full Time

Pontificia Universidad Católica de Chile

Santiago, Chile

2005 - 2007
Profesor Asistente Adjunto Escuela de Medicina Full Time

Pontificia Universidad Católica de Chile

Santiago, Chile

2007 - 2010
Profesor Asistente Escuela de Medicina Full Time

Pontificia Universidad Católica de Chile

Santiago, Chile

2010 - 2014

TESISTAS DE PREGRADO

Catalina Correa (2020)
Efecto del ácido docosahexaenoico en la expresión de genes pro-inflamatorios en células endoteliales de arterias de cordón umbilical de mujeres con obesidad
pre-gestacional.
Bioquímico, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile

Estefanía Peñaloza (2017)
Efecto de la hipoxia sobre de los niveles de los micro-RNAs miR-21 y miR-126 en células endoteliales de cordón umbilical humano y su relación con la regulación de la actividad de eNOS. (Co-Tutor, Tutor Dr. Bernardo Krause)
Bioquímico, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile

Amanda Silva (2013)
Regulación reciproca de eNOS y arginasa-2 en endotelio placentario de fetos con RCIU.
Licenciada en Biología, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile

Francisco Minaya (2010)
Regulación del transporte de adenosina por activación de purinoreceptores A2a y A1 en células endoteliales de vena umbilical humana.
Bioquímico, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile

Claudia Lavín (2010)
Participación de los aminoácidos L-citrulina y L-arginina en la vasodilatación mediada por óxido nítrico en arterias coriónicas de fetos con Restricción del Crecimiento Intrauterino.
Licenciada en Biología, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile

Carlos Puebla (2008)
Regulación transcripcional del promotor del gen SLC29A1 para el transportador equilibrativo de nucleósidos tipo 1 (hENT1) por D-glucosa en endotelio fetal humano
Bioquímico, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile

Catalina Prieto (2006)
Efecto de hipoxia sobre la expresión y actividad de eNOS y su regulación por arginasa en células endoteliales de vena umbilical humana.
Licenciada en Biología, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile

TESISTAS DE POSTGRADO

Viviana Arroyo (en desarrollo desde Mayo 2018)
Participación de la leptina en la programación de la función de las células T reguladoras en hijos de madres con obesidad pregestacional.
Doctorado en Nutrición y Alimentos, INTA, Universidad de Chile.

Erika Castaño (en desarrollo desde Abril 2018)
The altered lipid metabolism in offspring of women with pregestational obesity and with Folate/Vitamin B12 imbalance, is reverted by maternal DHA supplementation.
Doctorado en Nutrición y Alimentos, INTA, Universidad de Chile.

Ángela Jaramillo (Mayo 2020)
Cantidad y calidad de la grasa corporal al nacimiento y a los 4 meses de edad en hijos de madres con obesidad pregestacional y suplementación con DHA durante la gestación.
Doctorado en Nutrición y Alimentos, INTA, Universidad de Chile.

Ivo Carrasco (Junio 2019)
Epigenetic programming of Nrf2?dependent genes in human umbilical artery endothelium in macrosomic babies from obese mothers.
Doctorado en Ciencias Biológicas, mención Biología Celular y Molecular, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile.

Estefanía Muñoz (Marzo 2018)
Los fetos grandes para la edad gestacional presentan alteraciones en la función vascular placentaria y umbilical asociadas a niveles elevados de adiponectina en el plasma.
Doctorado en Nutrición y Alimentos, INTA, Universidad de Chile.

Ivo Carrasco (Enero 2015).
MicroRNAs en plasma como marcadores epigenéticos de disfunción metabólica temprana en niños prepuberales.
Magister en Ciencias Médicas, Mención Biología Celular y Molecular. Escuela de Medicina. Universidad de Valparaíso.

Ernesto Muñoz (Diciembre 2013)
Participación del estrés oxidativo en la disfunción placentaria observada en Restricción del Crecimiento Fetal.
Magister en Ciencias Biológicas, mención Ciencias Fisiológicas, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile.

Bernardo Krause (Noviembre 2012)
Mecanismos epigenéticos implicados en la programación de la función endotelial en fetos con Restricción del Crecimiento Intrauterino.
Doctorado en Ciencias Biológicas, mención Ciencias Fisiológicas, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile.

Catalina Prieto (Marzo 2012)
Determinación de la expresión y regulación funcional de Arginasa II y eNOS en células endoteliales de la vena umbilical humana en hipoxia.
Doctorado en Ciencias Biológicas, mención Ciencias Fisiológicas, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile.

Carlos Puebla (Octubre 2011)
Papel del transporte y metabolismo de D-glucosa en la expresión y actividad del transportador equilibrativo de nucleosidos 1 (hENT1) en endotelio de vena umbilical humana.
Doctorado en Ciencias Biológicas, mención Ciencias Fisiológicas, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile.

Victoria Gallardo (Enero 2008)
Regulación de la actividad de la ruta L-arginina /óxido nítrico por heme oxigenasa-1 en el endotelio fetal humano.
Magister en Bioquímica, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile

Solicitud de Patente 2014-02403, PCT/CL2015/050035 Chile. (11/09/2014) "Procedimiento para la síntesis enantioselectiva y purificación del ácido 2(S)-Amino-6-Boronohexanoico (ABH) e intermedios claves sintéticos." Preite Marcelo, Manríquez Juan, Correa Jordán, Iturriaga Rodrigo, Casanello Paola, Krause Bernardo.

Solicitud de Patente 2016-02951, PCT/CL2016/050062 Chile. (18/11/2016) “Combinación farmacéutica para el tratamiento y prevención de la hipertensión arterial y disfunción vascular” Preite Marcelo, Del Río Rodrigo, Iturriaga Rodrigo, Casanello Paola, Krause Bernardo.

Mejor Investigador Junior 2012 de la Escuela de Medicina de la Pontificia Universidad Católica de Chile

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Chile, 2013

Premio al mejor investigador joven en la Escuela de Medicina de la Pontificia Universidad Católica el año 2012. Es una distinción importante y competitiva dentro de la carrera académica de la Escuela de Medicina.
Best poster presentation in DOHaD World Congress

DOHaD International Society

Singapur, 2013

El trabajo presentado en proteoma de endotelio placentario de fetos con restricción de crecimiento vs fetos con trayectorias de crecimiento normal ganó el premio a uno de los mejores 10 trabajos presentados (de cerca de 600) en este congreso, que se celebra cada dos años. Este trabajo fue luego publicado en la revista de la especialidad Placenta.
Ex-alumna distinguida

UNIVERSIDAD DE CONCEPCION

Chile, 2019

Exalumna distinguida, invitada a dictar la conferencia central de la ceremonia de conmemoración de 95 años de la Facultad de Medicina, Universidad de Concepción
Expositora en Congreso del Futuro, Comisión del Senado, Chile

CONGRESO NACIONAL

Chile, 2017

Expositora en Congreso del Futuro, Comisión del Senado, Chile
Invitación reunión expertos OMS

ORGANIZACION MUNDIAL DE LA SALUD

Suiza, 2016

Invitación a “Expert meeting on avoidable Early Environmental Exposures” de la Organización Mundial de la Salud, 13-14 de Junio, Ginebra, Suiza.
DOHaD Directive Council member

UNIVERSITY OF SOUTHAMPTON

Reino Unido

Nombrada Miembro del Consejo Directivo Internacional de DOHaD, representando a las Ciencias Biomédicas (activa entre 2013 y 2017).
Ciencia de Frontera

ACADEMIA CHILENA DE CIENCIAS

Chile, 2012

Miembro del Programa “Ciencia de Frontera 2012-2014” de la Academia Chilena de Ciencias
DOHaD Recognized Health Educator Award

International DOHaD Society

Estados Unidos

DOHaD Recognized Health Educator Award to attend DOHaD 7th Word Congress, Portland, Oregon, USA.
Distinción Máxima Tesis Doctoral

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Chile, 2007

Distinción Máxima Tesis Doctoral: “Caracterización de las vías de señalización involucradas en la disminución de la actividad de la ruta L-arginina/óxido nítrico endotelial en restricción del crecimiento intrauterino e hipoxia”
Travel Award

Physiological Society

Reino Unido, 2004

Beca Physiological Society para viaje y participación en Reunión conjunta Sociedad Chilena de Ciencias Fisiológicas y Physiological Society, UK (Diciembre 2004)
Research Visit Award

Wellcome Trust

Chile, 2003

Beca Wellcome Trust para Visita de Investigación al Kings College London, University of London, UK – Microarreglos de genes en endotelio de vena umbilical de fetos con RCF (Enero - Abril 2003)
Best presentation I Latin American Symposium on Maternal-Fetal interaction

I Latin American Symposium on Maternal-Fetal Interaction & Placenta (SLIMP)

Brasil, 2003

Premio al mejor trabajo presentado. I Simposio Latinoamericano sobre Interacción Materno-Fetal Placenta, Sao Paulo, Brasil.


Prevalence of filaggrin loss-of-function variants in Chilean population with and without atopic dermatitis Cardenas, Geovanna V.; Iturriaga, Carolina; Hernandez, Caroll D.; Tejos-Bravo, Macarena; Perez-Mateluna, Guillermo; Cabalin, Carolina; Urzua, Marcela; Venegas-Salas, Luis F.; Fraga, Juan P.; Rebolledo, Boris; Poli, Maria C.; Repetto, Gabriela M.; Casanello, Paola; Castro-Rodriguez, Jose A.; Borzutzky, Arturo Article ISI INTERNATIONAL JOURNAL OF DERMATOLOGY (2022)
Gestational diabesity and foetoplacental vascular dysfunction Cornejo, Marcelo; Fuentes, Gonzalo; Valero, Paola; Vega, Sofia; Grismaldo, Adriana; Toledo, Fernando; Pardo, Fabian; Moore-Carrasco, Rodrigo; Subiabre, Mario; Casanello, Paola; Faas, Marijke M.; van Goor, Harry; Sobrevia, Luis Article ISI ACTA PHYSIOLOGICA (2021)
Early origins of allergy and asthma (ARIES): study protocol for a prospective prenatal birth cohort in Chile Hernandez, Caroll D.; Casanello, Paola; Harris, Paul R; Castro-Rodriguez, Jose A.; Iturriaga, Carolina; Perez-Mateluna, Guillermo; Farias, Marcelo; Urzua, Marcela; Hernandez, Cherie; Serrano, Carolina; Sandoval, Mauricio; Hoyos-Bachiloglu, Rodrigo; Uauy, Ricardo; borzutzky, arturo Article ISI BMC PEDIATRICS (2020)
Effectiveness of a normative nutrition intervention in Chilean pregnant women on maternal and neonatal outcomes: the CHiMINCs study Garmendia ML, Corvalan C, Araya M, Casanello P, Kusanovic JP, Uauy R. Article WOS indexing In press (paper accepted) AMERICAN JOURNAL OF CLINICAL NUTRITION (2020)
Evaluation of the Stability of Fatty Acids in Erythrocytes from Human Umbilical Cord Jaramillo A.M.; Garmendia, M.L.; MuÃ±oz P.; Corbari A.; Valenzuela R.; Casanello P. Article ISI SCOPUS LIPIDS (2020)
Leptin in Cord Blood Associates with Asthma Risk at Age 3 in the Offspring of Women with Gestational Obesity Castro-Rodriguez, Jose A.; Forno, Erick; Casanello, Paola; Padilla, Oslando; Krause, Bernardo J.; Uauy, Ricardo Article ISI ANNALS OF THE AMERICAN THORACIC SOCIETY (2020)
Maternal obesity is associated with a sex-specific epigenetic programming in human neonatal monocytes Vega-Tapia, Fabian; Artigas, Rocio; Hernandez, Cherie; Uauy, Ricardo; Casanello, Paola; Krause, Bernardo J.; Castro-Rodriguez, Jose A. Article ISI EPIGENOMICS (2020)
Human umbilical artery endothelial cells from Large-for-Gestational-Age newborn have increased antioxidant efficiency and gene expression Carrasco-Wong, Ivo; Hernandez, Cherie; Jara-Gutierrez, Carlos; Porras, Omar; Casanello, Paola Article ISI SCOPUS JOURNAL OF CELLULAR PHYSIOLOGY (2019)
Chronic Intermittent Hypoxia-Induced Vascular Dysfunction in Rats is Reverted by -Acetylcysteine Supplementation and Arginase Inhibition. Krause, Bernardo J; Casanello, Paola; Dias, Ana C; Arias, Paulina; Velarde, Victoria; Arenas, German A; Preite, Marcelo D; Iturriaga, Rodrigo Article Frontiers in physiology (2018)
Chronic Intermittent Hypoxia-Induced Vascular Dysfunction in Rats is Reverted by N-Acetylcysteine Supplementation and Arginase Inhibition Krause, BJ; Casanello, P; Dias, AC; Arias, P; Velarde, V; Arenas, GA; Preite, MD; Iturriaga, R Article ISI SCOPUS FRONTIERS IN PHYSIOLOGY (2018)
Effectiveness on maternal and offspring metabolic control of a home-based dietary counseling intervention and DHA supplementation in obese/overweight pregnant women (MIGHT study): A randomized controlled trial-Study protocol Garmendia, María Luisa; Corvalán, Camila; Casanello, Paola; Araya, Marcela; Flores, Marcela; Bravo, Alfredo; Kusanovic, Juan Pedro; Olmos, Pablo; Uauy, Ricardo Article ISI SCOPUS CONTEMPORARY CLINICAL TRIALS (2018)
LGA-newborn from patients with pregestational obesity present reduced adiponectin-mediated vascular relaxation and endothelial dysfunction in fetoplacental arteries Munoz-Munoz, E; Krause, BJ; Uauy, R; Casanello, P Article ISI SCOPUS JOURNAL OF CELLULAR PHYSIOLOGY (2018)
LGA-newborn from patients with pregestational obesity present reduced adiponectin-mediated vascular relaxation and endothelial dysfunction in fetoplacental arteries. Muñoz-Muñoz, Estefanía; Krause, Bernardo J; Uauy, Ricardo; Casanello, Paola Article Journal of cellular physiology (2018)
Expression of teneurins is associated with tumor differentiation and patient survival in ovarian cancer. Graumann, Rebecca; Di Capua, Gabriella A; Oyarzún, Juan E; Vásquez, Marcos A; Liao, Christine; Brañes, Jorge A; Roa, Iván; Casanello, Paola; Corvalán, Alejandro H; Owen, Gareth I; Delgado, Iris; Zangemeister-Wittke, Uwe; Ziegler, Annemarie Article PloS one (2017)
IL-10 expression in macrophages from neonates born from obese mothers is suppressed by IL-4 and LPS/INFÎ³. Cifuentes-Zúñiga, Francisca; Arroyo-Jousse, Viviana; Soto-Carrasco, Gustavo; Casanello, Paola; Uauy, Ricardo; Krause, Bernardo J; Castro-Rodríguez, José A Article Journal of cellular physiology (2017)
N-Acetylcysteine, a glutathione precursor, reverts vascular dysfunction and endothelial epigenetic programming in intrauterine growth restricted guinea pigs. Herrera, Emilio A; Cifuentes-Zúñiga, Francisca; Figueroa, Esteban; Villanueva, Cristian; Hernández, Cherie; Alegría, René; Arroyo-Jousse, Viviana; Peñaloza, Estefania; Farías, Marcelo; Uauy, Ricardo; Casanello, Paola; Krause, Bernardo J Article The Journal of physiology (2017)
Arginase-2 is cooperatively up-regulated by nitric oxide and histone deacetylase inhibition in human umbilical artery endothelial cells Krause, BJ; Hernandez C.; Caniuguir, A; Vasquez-Devaud, P; Carrasco-Wong, I; Uauy R.; Casanello, P Article ISI SCOPUS BIOCHEMICAL PHARMACOLOGY (2016)
Arginase-2 is cooperatively up-regulated by nitric oxide and histone deacetylase inhibition in human umbilical artery endothelial cells. Krause BJ, Hernandez C, Caniuguir A, Vasquez-Devaud P, Carrasco-Wong I, Uauy R, Casanello P. Article BIOCHEMICAL PHARMACOLOGY (2016)
Assessment of in vivo fetal growth and placental vascular function in a novel intrauterine growth restriction model of progressive uterine artery occlusion in guinea pigs Herrera, E. A.; Alegría R.; Farias M.; Díaz-López F.; Hernandez C.; Uauy R.; Regnault T.R.H.; Casanello, P; Krause, B. J. Article ISI SCOPUS JOURNAL OF PHYSIOLOGY-LONDON (2016)
Assessment of in vivo fetal growth and placental vascular function in a novel intrauterine growth restriction model of progressive uterine artery occlusion in guinea pigs. Herrera EA, Alegría R, Farias M, Díaz-López F, Hernández C, Uauy R, Regnault TR, Casanello P, Krause BJ. Article JOURNAL OF PHYSIOLOGY-LONDON (2016)
Epigenetics in allergic diseases and asthma Castro-Rodríguez JA, Krause BJ, Uauy R, Casanello P. Article Revista Chilena de Pediatria (2016)
General concepts of epigenetics: Projections in paediatrics Krause BJ, Castro-Rodríguez JA, Uauy R, Casanello P. Article Revista Chilena de Pediatria (2016)
Markers of early endothelial dysfunction in intrauterine growth restriction-derived human umbilical vein endothelial cells revealed by 2D-DIGE and mass spectrometry analyses Caniuguir, A; Krause, B. J.; Hernandez C.; Uauy R.; Casanello, P Article ISI SCOPUS PLACENTA (2016)
Markers of early endothelial dysfunction in intrauterine growth restriction-derived human umbilical vein endothelial cells revealed by 2D-DIGE and mass spectrometry analyses. Caniuguir A, Krause BJ, Hernandez C, Uauy R, Casanello P. Article PLACENTA (2016)
Placental epigenetic programming in intrauterine growth restriction (IUGR) Casanello P, Castro-Rodríguez JA, Uauy R, Krause BJ. Article Revista Chilena de Pediatria (2016)
Arginase-endothelial nitric oxide synthase imbalance contributes to endothelial dysfunction during chronic intermittent hypoxia Krause, B. J.; Del Rio R.; Moya E.A.; Marquez-Gutierrez M.; Casanello, P; Iturriaga R. Article ISI SCOPUS JOURNAL OF HYPERTENSION (2015)
Arginase-endothelial nitric oxide synthase imbalance contributes to endothelial dysfunction during chronic intermittent hypoxia. Krause BJ, Del Rio R, Moya EA, Marquez-Gutierrez M, Casanello P, Iturriaga R. Article JOURNAL OF HYPERTENSION (2015)
Effectiveness of a normative nutrition intervention (diet, physical activity and breastfeeding) on maternal nutrition and offspring growth: the Chilean maternal and infant nutrition cohort study (CHiMINCs) Garmendia, ML; Corvalán C.; Araya M.; Casanello, P; Kusanovic, JP; Uauy R. Article ISI SCOPUS BMC Pregnancy and Childbirth (2015)
Effectiveness of a normative nutrition intervention (diet, physical activity and breastfeeding) on maternal nutrition and offspring growth: the Chilean maternal and infant nutrition cohort study (CHiMINCs). Garmendia ML, Corvalan C, Araya M, Casanello P, Kusanovic JP, Uauy R. Article BMC Pregnancy and Childbirth (2015)
Fetal programming of chronic diseases: Current concepts and epigenetics Casanello P, Krause BJ, Castro-Rodriguez JA, Uauy R. Article Revista Chilena de Pediatria (2015)
Micro-RNAs Let7e and 126 in Plasma as Markers of Metabolic Dysfunction in 10 to 12 Years Old Children Krause, BJ; Carrasco-Wong, I; Dominguez A.; Arnaiz P.; Farias M.; Barja S.; Mardones F.; Casanello, P Article ISI SCOPUS PLOS ONE (2015)
Oxidative stress as common trait of endothelial dysfunction in chorionic arteries from fetuses with IUGR and LGA Schneider D.; Hernandez C.; Farias M.; Uauy R.; Krause, BJ; Casanello, P Article ISI SCOPUS Placenta (2015)
Oxidative stress as common trait of endothelial dysfunction in chorionic arteries from fetuses with IUGR and LGA. Schneider D, Hernández C, Farías M, Uauy R, Krause BJ, Casanello P. Article PLACENTA (2015)
Pre-gestational overweight in guinea pig sows induces fetal vascular dysfunction and increased rate of large and small fetuses. Krause BJ, Herrera EA, Díaz-López FA, Farías M, Uauy R, Casanello P. Article Journal of Developmental Origins of Health and Disease (2015)
Endothelial heterogeneity in the umbilico-placental unit: DNA methylation as an innuendo of epigenetic diversity. Casanello P, Schneider D, Herrera EA, Uauy R, Krause BJ. Article Frontiers in Pharmacology (2014)
Long-term impact of early life events on physiology and behaviour. Boersma GJ, Bale TL, Casanello P, Lara HE, Lucion AB, Suchecki D, Tamashiro KL. Article JOURNAL OF NEUROENDOCRINOLOGY (2014)
The placental pursuit for an adequate oxidant balance between the mother and the fetus. Herrera EA1, Krause B, Ebensperger G, Reyes RV, Casanello P, Parra-Cordero M, Llanos AJ. Article Frontiers in Pharmacology (2014)
5 '-ectonucleotidase mediates multiple-drug resistance in glioblastoma multiforme cells Quezada C.; Garrido, W; Oyarzún C.; Fernández K.; Segura, R; Melo, R; Casanello, P; Sobrevia L.; San Martín R. Article ISI SCOPUS JOURNAL OF CELLULAR PHYSIOLOGY (2013)
Conceptual basis for prescriptive growth standards from conception to early childhood: present and future Uauy R.; Casanello, P; Krause, B; Kuzanovic, JP; Corvalán C. Article ISI SCOPUS BJOG: An International Journal of Obstetrics and Gynaecology (2013)
Endothelial eNOS/arginase imbalance contributes to vascular dysfunction in IUGR umbilical and placental vessels Krause, BJ; Carrasco-Wong, I; Caniuguir, A; Carvajal, J.; Farias M.; Casanello, P Article ISI SCOPUS Placenta (2013)
Role of DNA methyltransferase 1 on the altered eNOS expression in human umbilical endothelium from intrauterine growth restricted fetuses Krause, BJ; Costello, PM; Munoz-Urrutia, E; Lillycrop, KA; Hanson, MA; Casanello, P Article ISI SCOPUS Epigenetics (2013)
The International Fetal and Newborn Growth Consortium for the 21st Century (INTERGROWTH-21st). Conceptual basis for prescriptive growth standards from conception to early childhood: present and future. Uauy R, Casanello P, Krause B, Kuzanovic J, Corvalan C. Article British Journal of Obstetrics and Gynecology (2013)
Gestational Diabetes Reduces Adenosine Transport in Human Placental Microvascular Endothelium, an Effect Reversed by Insulin Salomon, C; Westermeier, F; Puebla, C; Arroyo, P; Guzman-Gutierrez, E; Pardo F.; Leiva A.; Casanello, P; Sobrevia L. Article ISI SCOPUS PLOS ONE (2012)
Role of arginase-2 and eNOS in the differential vascular reactivity and hypoxia-induced endothelial response in umbilical arteries and veins Krause, B. J.; Prieto C.P.; Munoz-Urrutia, E; San Martin, S; Sobrevia L.; Casanello, P Article ISI SCOPUS Placenta (2012)
Role of arginase-2 and eNOS in the differential vascular reactivity and hypoxia-induced endothelial response in umbilical arteries and veins. Krause BJ, Prieto CP, Muñoz-Urrutia E, San Martín S, Sobrevia L, Casanello P. Article PLACENTA (2012)
Fetoplacental Vascular Endothelial Dysfunction as an Early Phenomenon in the Programming of Human Adult Diseases in Subjects Born from Gestational Diabetes Mellitus or Obesity in Pregnancy Leiva, A; Pardo, F; Ramirez, MA; Farias, M; Casanello P.; Sobrevia, L Article EXPERIMENTAL DIABETES RESEARCH (2011)
Functional Link Between Adenosine and Insulin: A Hypothesis for Fetoplacental Vascular Endothelial Dysfunction in Gestational Diabetes Guzman-Gutierrez, E; Abarzua, F; Belmar C.; Nien JK; Ramirez, MA; Arroyo, P; Salomon, C; Westermeier, F; Puebla, C; Leiva A.; Casanello, P; Sobrevia L. Article ISI SCOPUS CURRENT VASCULAR PHARMACOLOGY (2011)
Functional Link Between Adenosine and Insulin: A Hypothesis for Fetoplacental Vascular Endothelial Dysfunction in Gestational Diabetes Guzman-Gutierrez, E; Abarzua, F; Belmar C.; Nien, JK; Ramirez, MA; Arroyo P.; Salomon, C; Westermeier, F; Puebla, C; Leiva, A; Casanello P.; Sobrevia, L Article CURRENT VASCULAR PHARMACOLOGY (2011)
Hypoxia-reduced nitric oxide synthase activity is partially explained by higher arginase-2 activity and cellular redistribution in human umbilical vein endothelium Prieto CP; Krause, BJ; Quezada C.; San Martín R.; Sobrevia L.; Casanello, P Article ISI SCOPUS Placenta (2011)
Hypoxia-reduced nitric oxide synthase activity is partially explained by higher arginase-2 activity and cellular redistribution in human umbilical vein endothelium. Prieto CP, Krause BJ, Quezada C, San Martin R, Sobrevia L, Casanello P. Article PLACENTA (2011)
Increased expression of the multidrug resistance-associated protein 1 (MRP1) in kidney glomeruli of streptozotocin-induced diabetic rats Quezada C.; Alarcon S.; Carcamo, JG; Yañez A.; Casanello, P; Sobrevia L.; San Martín R. Article ISI SCOPUS Biological Chemistry (2011)
Increased expression of the multidrug resistance-associated protein 1 (MRP1) in kidney glomeruli of streptozotocin-induced diabetic rats Quezada C.; Alarcon, S; Carcamo, JG; Yanez, A; Casanello P.; Sobrevia, L; San Martin R. Article BIOLOGICAL CHEMISTRY (2011)
Insulin Restores Gestational Diabetes Mellitus Reduced Adenosine Transport Involving Differential Expression of Insulin Receptor Isoforms in Human Umbilical Vein Endothelium Westermeier, F; Salomon, C; Gonzalez, M.; Puebla, C; Guzman-Gutierrez, E; Cifuentes F.; Leiva A.; Casanello, P; Sobrevia L. Article ISI SCOPUS DIABETES (2011)
Insulin Restores Gestational Diabetes Mellitus Reduced Adenosine Transport Involving Differential Expression of Insulin Receptor Isoforms in Human Umbilical Vein Endothelium Westermeier, F; Salomon, C; Gonzalez, M; Puebla, C; Guzman-Gutierrez, E; Cifuentes, F; Leiva, A; Casanello P.; Sobrevia, L Article DIABETES (2011)
Insulin-Stimulated L-Arginine Transport Requires SLC7A1 Gene Expression and Is Associated With Human Umbilical Vein Relaxation Gonzalez, M; Gallardo, V; Rodriguez, N; Salomon, C; Westermeier, F; Guzman-Gutierrez, E; Abarzua, F; Leiva, A; Casanello P.; Sobrevia, L Article JOURNAL OF CELLULAR PHYSIOLOGY (2011)
Insulin-Stimulated L-Arginine Transport Requires SLC7A1 Gene Expression and Is Associated With Human Umbilical Vein Relaxation Gonzalez, M.; Gallardo V.; Rodríguez N.; Salomon, C; Westermeier, F; Guzman-Gutierrez, E; Abarzua, F; Leiva A.; Casanello, P; Sobrevia L. Article ISI SCOPUS JOURNAL OF CELLULAR PHYSIOLOGY (2011)
Review: Differential placental macrovascular and microvascular endothelial dysfunction in gestational diabetes Sobrevia L.; Salomon, C; Westermeier, F; Puebla, C; Cifuentes F.; Guzman-Gutierrez, E; Leiva A.; Casanello, P; Abarzua, F; Nien, J. K. Article ISI SCOPUS Placenta (2011)
Role of Nitric Oxide in Placental Vascular Development and Function. Krause BJ, Hanson MA, Casanello P. Article PLACENTA (2011)
ACTIVITY AND EXPRESSION OF HUMAN EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 1 IS REGULATED BY D-GLUCOSE UPTAKE AND METABOLISM IN UMBILICAL VEIN ENDOTHELIUM Puebla, C; Casanello P.; Sobrevia, L Article PLACENTA (2010)
Antagonic Role of Adenosine A(2A) and A(2B) Receptors on L-Arginine/Nitric Oxide Pathway in Human Placental Microvascular Endothelial Cells from Pre-Eclampsia Escudero, C; Casanello P.; Sobrevia, L Article REPRODUCTIVE SCIENCES (2010)
DIFFERENTIAL MODULATION OF INSULIN RECEPTOR ISOFORMS EXPRESSION AND NOS ACTIVITY BY INSULIN IN HUMAN PLACENTA MICROVASCULAR ENDOTHELIAL CELLS FROM GESTATIONAL DIABETES Salomon, C; Westermeier, F; Casanello P.; Sobrevia, L Article PLACENTA (2010)
Expression and Activity of Human Equilibrative Nucleoside Transporter 1 Depends on D-Glucose Uptake in Umbilical Vein Endothelial Cells. Puebla, C; Sepulveda, CA; Casanello P.; Sobrevia, L Article REPRODUCTIVE SCIENCES (2010)
Functional evidences of fetal endothelial dysfunction as a programmed phenomenon in pregnancy diseases Sobrevia, L; Casanello P. Article FASEB JOURNAL (2010)
HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS EXHIBIT GLUTS-LIKE TRANSPORT ACTIVITY MODULATED BY INSULIN Sepulveda, C; Puebla, C; Casanello P.; Sobrevia, L Article PLACENTA (2010)
Hypoxia-Reduced eNOS Activity Could Be Explained by Higher Arginase II Activity and Cellular Redistribution in Human Umbilical Vein Endothelial Cells Prieto, CP; Krause, B; Sobrevia, L; Casanello P. Article REPRODUCTIVE SCIENCES (2010)
Nitric oxide reduces SLC29A1 promoter activity and adenosine transport involving transcription factor complex hCHOP-C/EBP alpha in human umbilical vein endothelial cells from gestational diabetes Farias, M; Puebla, C; Westermeier, F; Jo, MJ; Pastor-Anglada, M; Casanello P.; Sobrevia, L Article CARDIOVASCULAR RESEARCH (2010)
Nitric oxide reduces SLC29A1 promoter activity and adenosine transport involving transcription factor complex hCHOP-C/EBP alpha in human umbilical vein endothelial cells from gestational diabetes Farias M.; Puebla, C; Westermeier, F; Jo, MJ; Pastor-Anglada, M; Casanello, P; Sobrevia L. Article ISI SCOPUS CARDIOVASCULAR RESEARCH (2010)
Nitric oxide reduces SLC29A1 promoter activity and adenosine transport involving transcription factor complex hCHOP-C/EBP? in human umbilical vein endothelial cells from gestational diabetes Farias M.; Puebla, C; Westermeier, F; Jo M.J.; Casanello, P; Sobrevia L.; Pastor-Anglada, M Article CARDIOVASCULAR RESEARCH (2010)
PARTICIPATION OF ARGINASES IN THE VASCULAR TONE IN UMBILICAL VEIN FROM IUGR PLACENTAE: ROLE OF THE ENDOTHELIUM AND HYPOXIA Munoz, E; Krause, B; Prieto C.; Lavin C.; Sobrevia, L; Casanello P. Article PLACENTA (2010)
RHOA/ROCK SIGNALLING PATHWAY IS NOT IMPLICATED IN ENOS INACTIVATION BY HYPOXIA IN HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS Prieto, CP; Sobrevia, L; Casanello P. Article PLACENTA (2010)
Role of Arginase II in the Vascular Function of Umbilical Arteries and Veins: Effect of Hypoxia Krause, B; Prieto C.; Sobrevia, L; Casanello P. Article REPRODUCTIVE SCIENCES (2010)
THE REDUCED NOS-DEPENDENT VASODILATION IN IUGR CHORIONIC ARTERIES IS IMPROVED BY ARGINASE INHIBITION Krause, BJ; Munoz, E; Lavin C.; Sobrevia, L; Casanello P. Article PLACENTA (2010)
Adenosine A(2B) Receptors Are Involved in the Regulation of Nitric Oxide Synthesis in Placental Microvascular Endothelial Cells from Preeclamptic Pregnancies Escudero, C; Myatt, L; Casanello P.; Sobrevia, L Article REPRODUCTIVE SCIENCES (2009)
Brain natriuretic peptide (BNP) produced by the human chorioamnion may mediate pregnancy myometrial quiescence. Carvajal, Jorge A; Delpiano, Ana M; Cuello, Mauricio A; Poblete, Jose A; Casanello, Paola C; Sobrevia, Luis A; Weiner, Carl P Article Reproductive sciences (Thousand Oaks, Calif.) (2009)
Epigenetics: New Concepts of Old Phenomena in Vascular Physiology Krause, B; Sobrevia L.; Casanello, P Article ISI CURRENT VASCULAR PHARMACOLOGY (2009)
Epigenetics: New Concepts of Old Phenomena in Vascular Physiology Krause, B; Sobrevia, L; Casanello P. Article CURRENT VASCULAR PHARMACOLOGY (2009)
Epigenetics: new concepts of old phenomena in vascular physiology. Krause B, Sobrevia L, Casanello P. Article Current Vascular Pharmacology (2009)
Equilibrative Nucleoside Transporters in Fetal Endothelial Dysfunction in Diabetes Mellitus and Hyperglycaemia Westermeier, F; Puebla, C; Vega, JL; Farias, M; Escudero, C; Casanello P.; Sobrevia, L Article CURRENT VASCULAR PHARMACOLOGY (2009)
Reduced L-Arginine Transport and Nitric Oxide Synthesis in Human Umbilical Vein Endothelial Cells from Intrauterine Growth Restriction Pregnancies is Not Further Altered by Hypoxia Casanello, P; Krause, B; Torres E.; Gallardo V.; Gonzalez, M.; Prieto, C; Escudero, c; Farias M.; Sobrevia L. Article ISI SCOPUS PLACENTA (2009)
Reduced L-Arginine Transport and Nitric Oxide Synthesis in Human Umbilical Vein Endothelial Cells from Intrauterine Growth Restriction Pregnancies is Not Further Altered by Hypoxia Casanello P.; Krause, B; Torres E.; Gallardo, V; Gonzalez, M; Prieto C.; Escudero, C; Farias, M; Sobrevia, L Article PLACENTA (2009)
Reduced L-arginine transport and nitric oxide synthesis in human umbilical vein endothelial cells from intrauterine growth restriction pregnancies is not further altered by hypoxia. Casanello P, Krause B, Torres E, Gallardo V, González M, Prieto C, Escudero C, Farías M, Sobrevia L. Article Placenta (2009)
TGF-?1 inhibits expression and activity of hENT1 in a nitric oxide-dependent manner in human umbilical vein endothelium Vega, J. L.; Puebla, C; Vasquez R.; Farias M.; Krause, B; Casanello, P; Sobrevia L.; Alarcon J.; Pastor-Anglada, M Article CARDIOVASCULAR RESEARCH (2009)
TGF-beta 1 inhibits expression and activity of hENT1 in a nitric oxide-dependent manner in human umbilical vein endothelium Vega, JL; Puebla, C; Vasquez R.; Farias M.; Alarcon J.; Pastor-Anglada, M; Krause, B; Casanello, P; Sobrevia L. Article ISI SCOPUS CARDIOVASCULAR RESEARCH (2009)
TGF-beta 1 inhibits expression and activity of hENT1 in a nitric oxide-dependent manner in human umbilical vein endothelium Vega, JL; Puebla, C; Vasquez, R; Farias, M; Alarcon, J; Pastor-Anglada, M; Krause, B; Casanello P.; Sobrevia, L Article CARDIOVASCULAR RESEARCH (2009)
Upregulation of Arginase II in Hypoxia Counteracts Nitric Oxide Synthesis in Human Umbilical Vein Endothelial Cells Prieto C.; Krause, B; Torres E.; Sobrevia, L; Casanello P. Article REPRODUCTIVE SCIENCES (2009)
Adenosine, L-Arginine and Nitric Oxide Pathway in Human Placental Microvascular Endothelial Cells Derived from Preeclampsia. Escudero, C; Myatt, L; Webster, R; Casanello P.; Sobrevia, L Article HYPERTENSION IN PREGNANCY (2008)
Brain natriuretic peptide (BNP) decreases expression and activity of eNOS and iNOS in primary human myometrial cell cultures Carvajal, JA; Delpiano, AM; Escudero, C; Casanello P.; Sobrevia, L; Cuello, MA; Weiner, CP Article REPRODUCTIVE SCIENCES (2008)
Carbon monoxide: a novel pulmonary artery vasodilator in neonatal llamas of the Andean altiplano Herrera EA; Reyes,RV; Giussani, DA; Riquelme, RA; Sanhueza, EM; Ebensperger G.; Casanello, P; Mendez, N.; Ebensperger, R; Sepulveda-Kattan, E; Pulgar VM; Cabello, G; Blanco, CE; Hanson, MA; Parer, JT; Llanos, AJ Article ISI SCOPUS CARDIOVASCULAR RESEARCH (2008)
Carbon monoxide: a novel pulmonary artery vasodilator in neonatal llamas of the Andean altiplano Herrera, EA; Reyes, RV; Giussani, DA; Riquelme, RA; Sanhueza, EM; Ebensperger, G; Casanello P.; Mendez, N; Ebensperger, R; Sepulveda-Kattan, E; Pulgar, VM; Cabello G.; Blanco, CE; Hanson, MA; Parer, JT; Llanos, AJ Article CARDIOVASCULAR RESEARCH (2008)
Characterization of adenosine, L-arginine, and nitric oxide pathway in human placental microvascular endothelial cells derived from preeclampsia Escudero, C; Myatt, L; Casanello P.; Sobrevia, L Article PLACENTA (2008)
D-Glucose increases the expression and activity of hCAT-1 and Spl binding to SLC7A1 promoter in human umbilical vein endothelium Gonzalez, M; Farias, M; Casanello P.; Sobrevia, L Article FASEB JOURNAL (2008)
Gestational diabetes mellitus is associated with NO and PKC-dependent repressor effect of hCHOP-C/EBPalpha on equilibrative nucleoside transporter 1 expression human umbilical vein endothelium Farias, M; Puebla, C; Vega, JL; Pastor-Anglada, M; Casanello P.; Sobrevia, L Article PLACENTA (2008)
High D-Glucose reduces SLC29A1 promoter activity and adenosine transport involving specific protein 1 in human umbilical vein endothelium Puebla, C; Farias M.; Gonzalez, M.; Vecchiola, A; Aguayo, C.; Krause, B; Pastor-Anglada, M; Casanello, P; Sobrevia L. Article ISI SCOPUS JOURNAL OF CELLULAR PHYSIOLOGY (2008)
High D-Glucose reduces SLC29A1 promoter activity and adenosine transport involving specific protein 1 in human umbilical vein endothelium Puebla, C; Farias, M; Gonzalez, M; Vecchiola, A; Aguayo, C; Krause, B; Pastor-Anglada, M; Casanello P.; Sobrevia, L Article JOURNAL OF CELLULAR PHYSIOLOGY (2008)
Human equilibrative nucleoside transporters 1 and 2 may be differentially modulated by A(2B) adenosine receptors in placenta microvascular endothelial cells from pre-eclampsia Escudero, C; Casanello P.; Sobrevia, L Article PLACENTA (2008)
Human equilibrative nucleoside transporters 1 and 2 may be differentially modulated by A(2B) adenosine receptors in placenta microvascular endothelial cells from pre-eclampsia Escudero, c; Casanello, P; Sobrevia L. Article ISI SCOPUS PLACENTA (2008)
Hypoxia upregulates the expression of arginase II in human umbilical vein endothelial cells. Regulating the nitric oxide synthase activity Prieto, CP; Krause, BJ; Torres E.; Sobrevia, L; Casanello P. Article PLACENTA (2008)
TGF-beta 1 inhibits adenosine transport in human fetal endothelium Vega, JL; Farias, M; Puebla, C; Casanello P.; Sobrevia, L Article PURINERGIC SIGNALLING (2008)
The transcriptional repression of equilibrative nucleoside transporter 1 by D-glucose rfsponses to transcription factor Sp1 and ZBP-89 in human foetal endothelium Puebla, C; Farias, M; Vega, JL; Pastor-Anglada, M; Casanello P.; Sobrevia, L Article PLACENTA (2008)
Transforming growth factor beta 1 is involved in the inhibitory effect of high D-glucose on human equilibrative nucleosidie transporter 1 in human fetal endothelium Vega, JL; Farias, M; Puebla, C; Gonzalez, M; Casanello P.; Sobrevia, L Article PLACENTA (2008)
ALANO pathway in the feto-placental endothelium from gestational diabetes Sobrevia, L; Farias, M; Escudero, C; Casanello P. Article PLACENTA (2007)
D-Glucose stimulation of L-arginine transport and nitric oxicle synthesis results from activation of mitogen-activated protein kinases p42/44 and smad2 requiring functional type II TGF-beta receptors in human umbilical vein endothelium Vaquez, R; Farias M.; Vega, JL; Martin, RS; Vecchiola, A; Casanello, P; Sobrevia L. Article ISI SCOPUS JOURNAL OF CELLULAR PHYSIOLOGY (2007)
D-Glucose stimulation of L-arginine transport and nitric oxicle synthesis results from activation of mitogen-activated protein kinases p42/44 and smad2 requiring functional type II TGF-beta receptors in human umbilical vein endothelium Vaquez, R; Farias, M; Vega, JL; Martin, RS; Vecchiola, A; Casanello P.; Sobrevia, L Article JOURNAL OF CELLULAR PHYSIOLOGY (2007)
D-glucose stimulation of L-arginine transport and nitric oxide synthesis results from activation of mitogen-activated protein kinases p42/44 and Smad2 requiring functional type II TGF-? receptors in human umbilical vein endothelium Vasquez R.; Farias M.; Vega, J. L.; San Martín R.; Vecchiola, A; Casanello, P; Sobrevia L. Article JOURNAL OF CELLULAR PHYSIOLOGY (2007)
DISMINUCION DEL FLUJO PLACENTARIO EN PREECLAMPSIA SEVERA: ¿ESTA INVOLUCRADA ADENOSINA EN ESTE FENOMENO? Escudero, Carlos; Casanello, Paola; Sobrevia, Luis Article 1604-2004: SUPERNOVAE AS COSMOLOGICAL LIGHTHOUSES (2007)
Equilibrative nucleoside (ENTs) and cationic amino acid (CATs) transporters: Implications in foetal endothelial dysfunction in human pregnancy diseases Casanello P.; Escudero, C; Sobrevia, L Article CURRENT VASCULAR PHARMACOLOGY (2007)
Expression and activty of HENT1 and HENT2 are regulated by adenosine receptors in placenta microvascular endothelium from preeclampsia Escudero, C; Casanello P.; Sobrevia, L Article PEDIATRIC RESEARCH (2007)
Insulin increases adenosine transport via equilibrative nucleoside transporter 2 in human umbilical vein endothelium under normoxia or hypoxia. Cea, L; Casanello P.; Sobrevia, L Article PLACENTA (2007)
Lower activity of L-arginine-nitric oxide pathway is related to PKCA activation in human umbilical vein endothelium from intruterine growth restriction. Casanello P.; Prieto C.; Escudero, C; Sobrevia, L Article PLACENTA (2007)
Transcriptional repression of equilibrative nucleoside transporter 1 by D-glucose involves nitric oxide and Sp1 in human foetal endothelium Puebla, C; Farias, M; Vecchiola, A; Casanello P.; Sobrevia, L Article PLACENTA (2007)
Transforming growth factor beta 1 reduces expression and activity of equilibrative nucleoside transporter 1 in human fetal endothelium Vega, JL; Farias, M; Bravo C.; Vargas S.; Casanello P.; Sobrevia, L Article PLACENTA (2007)
Adenosine receptor A2A stimulation decreases nitric oxide synthesis in placental microvascular endothelial cells from women with preeclampsia and intrauterine growth restriction Escudero, CA; Casanello P.; Sobrevia, L Article EARLY HUMAN DEVELOPMENT (2006)
Adenosine transport via Equilibrative Nucleoside Transporters 1 and 2 are not modulated by insulin in human umbilical vein endothelium under hypoxia Cea, L; Sobrevia, L; Casanello P. Article PLACENTA (2006)
Alano pathway in human umbilical vein endothelium San Martin R.; Farias, M; Casanello P.; Sobrevia, L Article PLACENTA (2006)
Carbon monoxide (CO): A key vasodilator in the pulmonary circulation in the llama neonate Herrera, EA; Reyes, VR; Riquelme, RA; Sanhueza, EM; Ebensperger, G; Ebensperger, R; Casanello P.; Martinez G.; Llanos, AJ Article PLACENTA (2006)
D-GLUCOSE stimulates nitric oxide synthase via a mechanism that involves TGF-beta 1 in human foetal endothelium Vasquez, R; Casanello P.; Sobrevia, L Article PLACENTA (2006)
Differential femoral and pulmonary adrenergic vascular reactivity in high and low altitude newborn lambs Galvez, P; Krause, B; Casanello P.; Herrera, EA; Llanos, AJ Article PLACENTA (2006)
Differential regulation of adenosine transport by activation of A(2a) and A(1) purinoceptors in human umbilical vein endothelium Minaya, F; San Martin R.; Casanello P.; Sobrevia, L Article PLACENTA (2006)
Effect of insulin on L-arginine transport through system y(+)L in human umbilical vein endothelium Varas, J; Farias, M; Casanello P.; Sobrevia, L Article PLACENTA (2006)
Effects of insulin on the expression and activity of system y(+)L-mediated L-arginine transport in human umbilical vein endothelium Varas, J; Farias, M; Casanello P.; Sobrevia, L Article EARLY HUMAN DEVELOPMENT (2006)
Hemoxygenase expression in lung tissue from high and low altitude newborn lambs Martinez G.; Ebensperger, G; Krause, B; Casanello P.; Reyes, VR; Llanos, AJ Article PLACENTA (2006)
Hypoxia increases equilibrative nucleoside transporter 2 activity by a transcriptional independent mechanism in human umbilical vein endothelium Torres, A; San Martin R.; Farias, M; Sobrevia, L; Casanello P. Article PLACENTA (2006)
Hypoxia represses carbon monoxide/heme oxygenase (Co/Ho) system and downregulates L-arginine/nitric oxide (No) pathway in human umbilical vein endothelial cells (Huvec). Gallardo, V; Sobrevia, L; Casanello P. Article HYPERTENSION IN PREGNANCY (2006)
Hypoxia-induced heme oxygenase-1 regulates the L-arginine/nitric oxide pathway in human umbilical vein endothelium Gallardo, V; Sobrevia, L; Casanello P. Article PLACENTA (2006)
Inhibition of L-arginine transport and nitric oxide activity in human umbilical vein endothelium of newborn with intrauterine growth restriction: role of hypoxia and PKC Casanello P.; Gallardo, V; Prieto C.; Sobrevia, L Article EARLY HUMAN DEVELOPMENT (2006)
Insulin restores D-glucose reduced adenosine transport in human umbilical vein endothelium Munoz, G; Casanello P.; Sobrevia, L Article EARLY HUMAN DEVELOPMENT (2006)
Insulin restores glucose inhibition of adenosine transport by increasing the expression and activity of the equilibrative nucleoside transporter 2 in human umbilical vein endothelium Munoz, G; San Martin R.; Farias, M; Cea, L; Vecchiola, A; Casanello P.; Sobrevia, L Article JOURNAL OF CELLULAR PHYSIOLOGY (2006)
Insulin restores glucose inhibition of adenosine transport by increasing the expression and activity of the equilibrative nucleoside transporter 2 in human umbilical vein endothelium Muñoz G.; San Martín R.; Farias M.; Cea, L; Vecchiola, A; Casanello, P; Sobrevia L. Article ISI SCOPUS JOURNAL OF CELLULAR PHYSIOLOGY (2006)
Modulation of adenosine transport by insulin in human foetal endothelium Munoz, G; Cea, L; Casanello P.; Sobrevia, L Article PLACENTA (2006)
Nitric oxide reduces adenosine transporter ENT1 gene (SLC29A1) promoter activity in human fetal endotheliurn from gestational diabetes Farias, M; Martin, RS; Puebla, C; Pearson, JD; Casado, JF; Pastor-Anglada, M; Casanello P.; Sobrevia, L Article JOURNAL OF CELLULAR PHYSIOLOGY (2006)
Post-translational modulation of equilibrative nucleoside transporter 1 by D-glucose in human umbilical vein endothelium Puebla, C; Casanello P.; Sobrevia, L Article PLACENTA (2006)
Short-, but not long-term stimulation of L-arginine transport by D-glucose involves TGF-beta 1 in human foetal endothelium Vasquez, R; Casanello P.; Sobrevia, L Article PLACENTA (2006)
Effect of transforming growth factor beta 1 on L-arginine/nitric oxide pathway in human umbilical vein endothelium exposed to high D-glucose Vasquez, R; Casanello P.; Sobrevia, L Article PEDIATRIC RESEARCH (2005)
Equilibrative nucleoside transporter 1 expression is downregulated by hypoxia in human umbilical vein endothelium Casanello, P; Torres A.; Sanhueza, F; Gonzalez, M.; Farias M.; Gallardo V.; Pastor-Anglada, M; San Martín R.; Sobrevia L. Article ISI SCOPUS CIRCULATION RESEARCH (2005)
Equilibrative nucleoside transporter 1 expression is downregulated by hypoxia in human umbilical vein endothelium Casanello P.; Torres, A; Sanhueza, F; Gonzalez, M; Farias, M; Gallardo, V; Pastor-Anglada, M; San Martin R.; Sobrevia, L Article CIRCULATION RESEARCH (2005)
Equilibrative nucleoside transporter 1 is downregulated by activation of A(2a) adenosine receptors in human umbilical vein endothelium. Martin, RS; Minaya, F; Farias, M; Casanello P.; Sobrevia, L Article PEDIATRIC RESEARCH (2005)
Equilibrative nucleoside transporter 2 is expressed in human umbilical vein endothelium, but is not involved in the inhibition of adenosine transport induced by hyperglycaemia Aguayo, C.; Casado, J; Gonzalez, M.; Pearson, JD; San Martín R.; Casanello, P; Pastor-Anglada, M; Sobrevia L. Article ISI SCOPUS PLACENTA (2005)
Equilibrative nucleoside transporter 2 is expressed in human umbilical vein endothelium, but is not involved in the inhibition of adenosine transport induced by hyperglycaemia Aguayo, C; Casado, J; Gonzalez, M; Pearson, JD; San Martin R.; Casanello P.; Pastor-Anglada, M; Sobrevia, L Article PLACENTA (2005)
Gestational diabetes increases L-arginine transport via a P13-K-independent mechanism in human foetal endothelium Gonzalez, M; Casanello P.; Sobrevia, L Article PEDIATRIC RESEARCH (2005)
Heme oxygenase 1 regulates the L-arginine/nitric oxide pathway in hypoxia in human umbilical vein endothelium Casanello P.; Sobrevia, L; Gallardo, V Article PEDIATRIC RESEARCH (2005)
Insulin restores the elevated adenosine transport in human umbilical vein endothelial cells from intrauterine growth restriction pregnancies Sanhueza, F; Casanello P.; Sobrevia, L Article PEDIATRIC RESEARCH (2005)
Role of nitric oxide in the pulmonary circulation in high- and low-altitude newborn lambs. Llanos, AJ; Sepulveda-Kattan, E; Riquelme R.; Herrera E.; Sanhueza, E; Ebensperger, G; Ebensperger, R; Reyes, VR; Pulgar, VM; Casanello P.; Hanson, MA; Blanco, CE; Giussani, DA Article JOURNAL OF THE SOCIETY FOR GYNECOLOGIC INVESTIGATION (2005)
CELL SIGNALLING-MEDIATING INSULIN INCREASE OF MRNA EXPRESSION FOR CATIONIC AMINO ACID TRANSPORTERS-1 AND-2 AND MEMBRANE HYPERPOLARIZATION IN HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS Gonzalez, Marcelo; Flores, Carlos; Pearson, Jeremy; Casanello, Paola; Sobrevia, Luis Article PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2004)
Cell signalling-mediating insulin increase of mRNA expression for cationic amino acid transporters-1 and-2 and membrane hyperpolarization in human umbilical vein endothelial cells Gonzalez, M; Flores C.; Pearson, JD; Casanello P.; Sobrevia, L Article PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2004)
Expression of equilibrative nucleoside transporters 1 is modulated by hypoxia in human umbilical vein endothelial cells Torres, A; Aedo, I; Sanhueza, F; Gonzalez, M; Casanello P.; Sobrevia, L Article PLACENTA (2004)
Role of adenosine transport in gestational diabetes-induced L-arginine transport and nitric oxide synthesis in human umbilical vein endothelium Vasquez, G; Sanhueza, F; Vasquez, R; Gonzalez, M; San Martin R.; Casanello P.; Sobrevia, L Article JOURNAL OF PHYSIOLOGY-LONDON (2004)
Role of adenosine transport in gestational diabetes-induced L-arginine transport and nitric oxide synthesis in human umbilical vein endothelium VASQUEZ, G.; Sanhueza, F; Vasquez R.; Gonzalez, M.; San Martín R.; Casanello, P; Sobrevia L. Article ISI SCOPUS JOURNAL OF PHYSIOLOGY-LONDON (2004)
Transforming growth factor beta 1 increases L-arginine transport and expression of the human cationic amino acid transporter 1 mRNA in human umbilical vein endothelial cells Vasquez, R; Gonzalez, M; Casanello P.; Sobrevia, L Article PLACENTA (2004)
Hyperglycaemia inhibits thymidine incorporation and cell growth via protein kinase C, mitogen-activated protein kinases and nitric oxide in human umbilical vein endothelium Rojas, S.; Rojas, R.; Lamperti, L; Casanello, P; Sobrevia L. Article ISI EXPERIMENTAL PHYSIOLOGY (2003)
Hyperglycaemia inhibits thymidine incorporation and cell growth via protein kinase C, mitogen-activated protein kinases and nitric oxide in human umbilical vein endothelium Rojas S.; Rojas, R; Lamperti, L; Casanello P.; Sobrevia, L Article EXPERIMENTAL PHYSIOLOGY (2003)
Nitric oxide synthesis requires activity of the cationic and neutral amino acid transport system y(+)L in human umbilical vein endothelium Arancibia-Garavilla, Y; Toledo, F.; Casanello, P; Sobrevia L. Article ISI SCOPUS EXPERIMENTAL PHYSIOLOGY (2003)
Nitric oxide synthesis requires activity of the cationic and neutral amino acid transport system y(+)L in human umbilical vein endothelium Arancibia-Garavilla, Y; Toledo F.; Casanello P.; Sobrevia, L Article EXPERIMENTAL PHYSIOLOGY (2003)
Rapid stimulation of L-arginine transport by D-glucose involves P42/44(mapk) and nitric oxide in human umbilical vein endothelium Flores C.; Rojas S.; Aguayo, C; Parodi J.; Mann, G; Pearson, JD; Casanello P.; Sobrevia, L Article CIRCULATION RESEARCH (2003)
Rapid stimulation of L-arginine transport by D-glucose involves P42/44(mapk) and nitric oxide in human umbilical vein endothelium Flores C.; Rojas, S.; Aguayo, C.; Parodi, J; Mann G.; Pearson, JD; Casanello, P; Sobrevia L. Article ISI CIRCULATION RESEARCH (2003)
Inhibition of nitrobenzylthioinosine-sensitive adenosine transport by elevated D-glucose involves activation of P-2Y2 purinoceptors in human umbilical vein endothelial cells Parodi J.; Flores C.; Aguayo, C; Rudolph, MI; Casanello P.; Sobrevia, L Article CIRCULATION RESEARCH (2002)
Inhibition of nitrobenzylthioinosine-sensitive adenosine transport by elevated D-glucose involves activation of P-2Y2 purinoceptors in human umbilical vein endothelial cells Parodi, J; Flores C.; Aguayo, C.; Rudolph, MI; Casanello, P; Sobrevia L. Article ISI CIRCULATION RESEARCH (2002)
Inhibition of nitrobenzylthioinosine-sensitive adenosine transport by elevated elevated D-glucose involves activation of P 2Y2 purinoceptors in human umbilical vein endothelial cells Parodi, J; Flores C.; Aguayo, C.; Rudolph M.I.; Casanello, P; Sobrevia L. Article CIRCULATION RESEARCH (2002)
Intrauterine growth retardation is associated with reduced activity and expression of the cationic amino acid transport systems y(+)/hCAT-1 and y(+)/hCAT-2B and lower activity of nitric oxide synthase in human umbilical vein endothelial cells Casanello, P; Sobrevia L. Article ISI SCOPUS CIRCULATION RESEARCH (2002)
Intrauterine growth retardation is associated with reduced activity and expression of the cationic amino acid transport systems y(+)/hCAT-1 and y(+)/hCAT-2B and lower activity of nitric oxide synthase in human umbilical vein endothelial cells Casanello P.; Sobrevia, L Article CIRCULATION RESEARCH (2002)
Intra-uterine growth retardation is associated with reduced activity and expression of cationic amino acid transporters (system y(+)/CAT) and nitric oxide synthase in human umbilical vein endothelial cells Casanello P.; Sobrevia, L Article JOURNAL OF PHYSIOLOGY-LONDON (2001)
NITRIC OXIDE REDUCES ADENOSINE TRANSPORTER ENT1 GENE (SLC29A1) PROMOTER ACTIVITY IN HUMAN FETAL ENDOTHELIURN FROM GESTATIONAL DIABETES Farias, Marcelo; San Martin, Rody; Puebla, carlos; Pearson, Jeremy; Casado, Javier; Pastor-Anglada, Marcal; Casanello, Paola Article JOURNAL OF CELLULAR PHYSIOLOGY


DNA Methylation of nos3 Promoter in IUGR Guinea Pig Fetuses Does Not Predict Endothelial Function and DNA Methylation Later in Life Krause, BJ; Penaloza, E; Hernandez, C; Soto-Carrasco, G; Casanello, P; Uauy, R; Herrera EA Abstract ISI REPRODUCTIVE SCIENCES (2018)
Changes in the M1/M2 Responses and Epigenetic Markers in Neonatal Monocyte-Derived Macrophages from Women with Pre-Gestational Obesity. Krause, BJ; Cifuentes-Zuniga, F; Arroyo, V; Soto-Carrasco, G; Uauy, R; Casanello, P; Castro-Rodrguez, J Abstract ISI REPRODUCTIVE SCIENCES (2017)
INTRAUTERINE GROWTH TRAJECTORIES MODIFY THE EPIGENETIC PROGRAMMING OF VASCULAR-RELATED GENES IN HUMAN UMBILICAL ARTERY ENDOTHELIUM AND CORD ADIPONECTIN LEVELS Casanello, P; Hernandez, C; Carrasco-Wong, I; Munoz-Munoz, E; Jaramillo, A; Soto, G; Carrasco, K; Castro-Rodriguez, JA; Uauy, R; Krause, B Abstract ISI PLACENTA (2017)
Antioxidant and Angiotensin AT1 Receptor Antagonist Treatment Reduced the Hypertension Induced by Chronic Intermittent Hypoxia in rats, but had Different Effects on Endothelial Dysfunction Iturriaga, R; Krause, B; Casanello, P; Dias, ACR; Arias, P; del Rio, R Abstract ISI FASEB JOURNAL (2016)
ADIPONECTIN RECEPTOR 1 EXPRESSION IN HUMAN UMBILICAL ARTERY ENDOTHELIAL CELLS (HUAEC) FROM LARGE FETUSES (LGA) OF OBESE WOMEN IS RELATED TO eNOS ACTIVATION Munoz-Munoz, EC; Krause, B; Uauy R.; Casanello, P Abstract ISI PLACENTA (2015)
EPIGENETICS AND ENDOTHELIAL HETEROGENEITY IN THE UMBILICOPLACENTAL UNIT: A LANDSCAPE FOR EPIGENETIC PROGRAMMING OF VASCULAR FUNCTION Krause, B; Carrasco-Wong, I; Hernandez C.; Uauy R.; Casanello, P Abstract ISI PLACENTA (2015)
INTRAUTERINE GROWTH RESTRICTION IN GUINEA PIG IMPAIRS UMBILICAL AND SYSTEMIC VASCULAR FUNCTION Herrera EA; Schneider D.; Alegría R.; Figueroa, E.; Villanueva, C.; Farias M.; Casanello, P; Krause, BJ Abstract ISI PLACENTA (2015)
MATERNAL OBESITY IMPAIRS MIGRATION OF FETAL ENDOTHELIUM INVOLVING ENDOPLASMIC RETICULUM STRESS Villalobos-Labra, R; Sáez PJ; Gonzalez, I; Westermeier, F; Sobrevia L.; Casanello, P; Owen, GI; Farias-Jofre, M Abstract ISI PLACENTA (2015)
FOETAL AND UMBILICAL VASCULAR REACTIVITY IN A MODEL OF IUGR THROUGH GRADUAL UTERINE ARTERY OCCLUSION IN GUINEA PIGS Scheneider, D; Alegría R.; Herrera, E; Farias M.; Casanello, P; Krause, B Abstract ISI PLACENTA (2014)
HISTONE DEACETYLASE ACTIVITY AND NITRIC OXIDE CONTROL THE EXPRESSION OF ENOS AND ARGINASE-2 IN HUMAN UMBILICAL ARTERY ENDOTHELIUM IN INTRAUTERINE GROWTH RESTRICTION Krause, B; Hernandez C.; Schneider D.; Casanello, P Abstract ISI PLACENTA (2014)
MATERNAL OBESITY IS ASSOCIATED WITH AN ALTERED ANTIOXIDANT SYSTEM IN THE UMBILICAL ARTERY ENDOTHELIUM: NEW INSIGHTS INTO VASCULAR FETAL PROGRAMMING BY MATERNAL OBESITY? Carrasco, I; Porras O.; Casanello, P Abstract ISI PLACENTA (2014)
ROLE OF OXIDATIVE STRESS STATUS ON THE IMPAIRED ENOS-DEPENDENT RELAXATION IN PLACENTAL CHORIONIC ARTERIES OF INTRAUTERINE GROWTH RESTRICTED (IUGR) AND MACROSOMIC FETUSES FROM OBESE MOTHERS (FMOM) Schneider D.; Hernandez C.; Krause, B; Casanello, P Abstract ISI PLACENTA (2014)
Epigenetic mechanisms implicated in endothelial programming associated to IUGR: Insights from umbilical endothelium Krause, BJ; Carrasco-Wong, I; Casanello, P Abstract PLACENTA (2013)
The increase in oxidative stress in umbilical endothelium from IUGR pregnancies involves changes in GTPCH and DHFR expression Munoz-Urrutia, E; Casanello, P Abstract ISI PLACENTA (2013)
Maternal Supraphysiological Hypercholesterolemia Leads to Reduced Endothelium-Dependent Vasodilation of Human Umbilical Vein and Reduced Nitric Oxide Production in HUVEC. Leiva, AA; Guzman-Gutierrez, E; Abarzua, F; Casanello, P; Sobrevia, LA Abstract ISI REPRODUCTIVE SCIENCES (2012)
RhoA/ROCK Signaling Pathway Is Not Implicated in the Regulation of eNOS Activation and arginase-2 Expression in Human Umbilical Vein Endothelial Cells Exposed to Hypoxia. Prieto CP; Krause, BJ; Sobrevia L.; Casanello, P Abstract ISI REPRODUCTIVE SCIENCES (2012)
SREBP-1C AND HCHOP-C/EBP alpha INVOLVEMENT IN INSULIN MODULATION OF HENT2 ACTIVITY IN HUMAN PLACENTA MICROVASCULAR ENDOTHELIUM FROM GESTATIONAL DIABETES Salomon, C; Westermeier, F; Guzman-Gutierrez, E; Arroyo, P; Pardo F.; Leiva A.; Casanello, P; Mitchell M.; Rice, G; Sobrevia L. Abstract ISI PLACENTA (2012)
The Hypoxic Phenotype of IUGR Placental Endothelial Cells Is Reverted by DNMT1 Silencing. Evidence for Altered Epigenetic Vascular Programming. Krause, BJ; Sobrevia L.; Hanson, MA; Casanello, P Abstract ISI REPRODUCTIVE SCIENCES (2012)
Abnormal Expression of L-Arginine/NO-Related Enzymes in HUVEC Is Associated with Altered Vascular Reactivity of Umbilical Vein from IUGR Placentae Krause, BJ; Muñoz E; Prieto CP; Sobrevia L.; Casanello, P Abstract JOURNAL OF DEVELOPMENTAL ORIGINS OF HEALTH AND DISEASE (2011)
Altered Expression of L-Arginine/NO-Related Enzymes in Cultured Endothelial Cells from IUGR Placenta Is Accompanied by Specific DNA Methylation Changes Krause, BJ; Costello, P; Garrat, ES; Lillycrop, KA; Sobrevia L.; Hanson, MA; Casanello, P Abstract JOURNAL OF DEVELOPMENTAL ORIGINS OF HEALTH AND DISEASE (2011)
Differential Expression of A and B Isoforms of Insulin Receptor Are Involved in the Insulin-Mediated Recovery of Gestational Diabetes to Normal Phenotype in Human Placental Microvascular Endothelium Salomon, C; Westermeier, F; Guzman, E; Leiva A.; Casanello, P; Luis S Abstract JOURNAL OF DEVELOPMENTAL ORIGINS OF HEALTH AND DISEASE (2011)
INSULIN ACTIVATES EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 2 INVOLVING INSULIN RECEPTOR A IN HUMAN PLACENTA MICROVASCULAR ENDOTHELIAL CELLS FROM GESTATIONAL DIABETES Salomon, C; Westermeier, F; Guzman-Gutierrez, E; Leiva A.; Casanello, P; Sobrevia L. Abstract PLACENTA (2011)
INSULIN RECEPTOR A IS INVOLVED IN GESTATIONAL DIABETES-REDUCED ADENOSINE TRANSPORT VIA HUMAN EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 1 IN HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS Westermeier, F; Salomon, C; Guzman-Gutierrez, E; Puebla, C; Leiva A.; Casanello, P; Sobrevia L. Abstract PLACENTA (2011)
Insulin Reverses Gestational Diabetes-Increased L-Arginine Transport Via A(2A) Adenosine Receptors Activation in Human Umbilical Vein Endothelium Guzman-Gutierrez, E; Puebla, C; Salomon, C; Westermeier, F; Leiva A.; Casanello, P; Sobrevia L. Abstract JOURNAL OF DEVELOPMENTAL ORIGINS OF HEALTH AND DISEASE (2011)
Maternal Supraphysiological Hypercholesterolemia Leads to Reduced Endothelium-Dependent Vasodilation of Umbilical Vein and Increased L-Arginine Transport in HUVEC Leiva A.; Guzman-Gutierrez, E; Abarzua, F; Casanello, P; Sobrevia L. Abstract JOURNAL OF DEVELOPMENTAL ORIGINS OF HEALTH AND DISEASE (2011)
ACTIVITY AND EXPRESSION OF HUMAN EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 1 IS REGULATED BY D-GLUCOSE UPTAKE AND METABOLISM IN UMBILICAL VEIN ENDOTHELIUM Puebla, C; Casanello, P; Sobrevia L. Abstract PLACENTA (2010)
Antagonic Role of Adenosine A(2A) and A(2B) Receptors on L-Arginine/Nitric Oxide Pathway in Human Placental Microvascular Endothelial Cells from Pre-Eclampsia Escudero, c; Casanello, P; Sobrevia L. Abstract REPRODUCTIVE SCIENCES (2010)
DIFFERENTIAL MODULATION OF INSULIN RECEPTOR ISOFORMS EXPRESSION AND NOS ACTIVITY BY INSULIN IN HUMAN PLACENTA MICROVASCULAR ENDOTHELIAL CELLS FROM GESTATIONAL DIABETES Salomon, C; Westermeier, F; Casanello, P; Sobrevia L. Abstract PLACENTA (2010)
Expression and Activity of Human Equilibrative Nucleoside Transporter 1 Depends on D-Glucose Uptake in Umbilical Vein Endothelial Cells. Puebla, C; Sepulveda, CA; Casanello, P; Sobrevia L. Abstract REPRODUCTIVE SCIENCES (2010)
Functional evidences of fetal endothelial dysfunction as a programmed phenomenon in pregnancy diseases Sobrevia L.; Casanello, P Abstract ISI FASEB JOURNAL (2010)
HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS EXHIBIT GLUTS-LIKE TRANSPORT ACTIVITY MODULATED BY INSULIN Sepulveda, C; Puebla, C; Casanello, P; Sobrevia L. Abstract PLACENTA (2010)
Hypoxia-Reduced eNOS Activity Could Be Explained by Higher Arginase II Activity and Cellular Redistribution in Human Umbilical Vein Endothelial Cells Prieto CP; Krause, B; Sobrevia L.; Casanello, P Abstract REPRODUCTIVE SCIENCES (2010)
PARTICIPATION OF ARGINASES IN THE VASCULAR TONE IN UMBILICAL VEIN FROM IUGR PLACENTAE: ROLE OF THE ENDOTHELIUM AND HYPOXIA Muñoz E; Krause, B; Prieto, C; Lavin C.; Sobrevia L.; Casanello, P Abstract PLACENTA (2010)
RHOA/ROCK SIGNALLING PATHWAY IS NOT IMPLICATED IN ENOS INACTIVATION BY HYPOXIA IN HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS Prieto CP; Sobrevia L.; Casanello, P Abstract PLACENTA (2010)
Role of Arginase II in the Vascular Function of Umbilical Arteries and Veins: Effect of Hypoxia Krause, B; Prieto, C; Sobrevia L.; Casanello, P Abstract REPRODUCTIVE SCIENCES (2010)
THE REDUCED NOS-DEPENDENT VASODILATION IN IUGR CHORIONIC ARTERIES IS IMPROVED BY ARGINASE INHIBITION Krause, BJ; Muñoz E; Lavin C.; Sobrevia L.; Casanello, P Abstract PLACENTA (2010)
VASOCONSTRICTION INDUCED BY SEROTONIN IS REDUCED BY ADENOSINE IN HUMAN UMBILICAL VEINS FROM GESTATIONAL DIABETES Cifuentes F.; Palacios J.; Vega, JL; Casanello, P; Sobrevia L. Abstract PLACENTA (2010)
Adenosine A(2B) Receptors Are Involved in the Regulation of Nitric Oxide Synthesis in Placental Microvascular Endothelial Cells from Preeclamptic Pregnancies Escudero, c; Myatt L.; Casanello, P; Sobrevia L. Abstract REPRODUCTIVE SCIENCES (2009)
Upregulation of Arginase II in Hypoxia Counteracts Nitric Oxide Synthesis in Human Umbilical Vein Endothelial Cells Prieto, C; Krause, B; Torres E.; Sobrevia L.; Casanello, P Abstract REPRODUCTIVE SCIENCES (2009)
Adenosine, L-Arginine and Nitric Oxide Pathway in Human Placental Microvascular Endothelial Cells Derived from Preeclampsia. Escudero, c; Myatt L.; Webster R.; Casanello, P; Sobrevia L. Abstract Hypertension in Pregnancy (2008)
Brain natriuretic peptide (BNP) decreases expression and activity of eNOS and iNOS in primary human myometrial cell cultures Carvajal, JA; Delpiano, AM; Escudero, c; Casanello, P; Sobrevia L.; Cuello, MA; Weiner, CP Abstract REPRODUCTIVE SCIENCES (2008)
Characterization of adenosine, L-arginine, and nitric oxide pathway in human placental microvascular endothelial cells derived from preeclampsia Escudero, c; Myatt L.; Casanello, P; Sobrevia L. Abstract PLACENTA (2008)
D-Glucose increases the expression and activity of hCAT-1 and Spl binding to SLC7A1 promoter in human umbilical vein endothelium Gonzalez, M.; Farias M.; Casanello, P; Sobrevia L. Abstract ISI FASEB JOURNAL (2008)
Gestational diabetes mellitus is associated with NO and PKC-dependent repressor effect of hCHOP-C/EBPalpha on equilibrative nucleoside transporter 1 expression human umbilical vein endothelium Farias M.; Puebla, C; Vega, JL; Pastor-Anglada, M; Casanello, P; Sobrevia L. Abstract PLACENTA (2008)
Hypoxia upregulates the expression of arginase II in human umbilical vein endothelial cells. Regulating the nitric oxide synthase activity Prieto CP; Krause, BJ; Torres E.; Sobrevia L.; Casanello, P Abstract PLACENTA (2008)
TGF-beta 1 inhibits adenosine transport in human fetal endothelium Vega, JL; Farias M.; Puebla, C; Casanello, P; Sobrevia L. Abstract PURINERGIC SIGNALLING (2008)
The transcriptional repression of equilibrative nucleoside transporter 1 by D-glucose rfsponses to transcription factor Sp1 and ZBP-89 in human foetal endothelium Puebla, C; Farias M.; Vega, JL; Pastor-Anglada, M; Casanello, P; Sobrevia L. Abstract PLACENTA (2008)
Transforming growth factor beta 1 is involved in the inhibitory effect of high D-glucose on human equilibrative nucleosidie transporter 1 in human fetal endothelium Vega, JL; Farias M.; Puebla, C; Gonzalez, M.; Casanello, P; Sobrevia L. Abstract PLACENTA (2008)
ALANO pathway in the feto-placental endothelium from gestational diabetes Sobrevia L.; Farias M.; Escudero, c; Casanello, P Abstract PLACENTA (2007)
Expression and activty of HENT1 and HENT2 are regulated by adenosine receptors in placenta microvascular endothelium from preeclampsia Escudero, c; Casanello, P; Sobrevia L. Abstract PEDIATRIC RESEARCH (2007)
Insulin increases adenosine transport via equilibrative nucleoside transporter 2 in human umbilical vein endothelium under normoxia or hypoxia. Cea, L; Casanello, P; Sobrevia L. Abstract ISI PLACENTA (2007)
Lower activity of L-arginine-nitric oxide pathway is related to PKCA activation in human umbilical vein endothelium from intruterine growth restriction. Casanello, P; Prieto, C; Escudero, c; Sobrevia L. Abstract PLACENTA (2007)
Transcriptional repression of equilibrative nucleoside transporter 1 by D-glucose involves nitric oxide and Sp1 in human foetal endothelium Puebla, C; Farias M.; Vecchiola, A; Casanello, P; Sobrevia L. Abstract PLACENTA (2007)
Transforming growth factor beta 1 reduces expression and activity of equilibrative nucleoside transporter 1 in human fetal endothelium Vega, JL; Farias M.; Bravo C.; Vargas S.; Casanello, P; Sobrevia L. Abstract PLACENTA (2007)
Adenosine receptor A2A stimulation decreases nitric oxide synthesis in placental microvascular endothelial cells from women with preeclampsia and intrauterine growth restriction Escudero, CA; Casanello, P; Sobrevia L. Abstract ISI EARLY HUMAN DEVELOPMENT (2006)
Adenosine transport via Equilibrative Nucleoside Transporters 1 and 2 are not modulated by insulin in human umbilical vein endothelium under hypoxia Cea, L; Sobrevia L.; Casanello, P Abstract ISI PLACENTA (2006)
Alano pathway in human umbilical vein endothelium San Martín R.; Farias M.; Casanello, P; Sobrevia L. Abstract PLACENTA (2006)
Carbon monoxide (CO): A key vasodilator in the pulmonary circulation in the llama neonate Herrera EA; Reyes, VR; Riquelme, RA; Sanhueza, EM; Ebensperger G.; Ebensperger, R; Casanello, P; Martinez, G; Llanos, AJ Abstract PLACENTA (2006)
D-GLUCOSE stimulates nitric oxide synthase via a mechanism that involves TGF-beta 1 in human foetal endothelium Vasquez R.; Casanello, P; Sobrevia L. Abstract ISI PLACENTA (2006)
Differential femoral and pulmonary adrenergic vascular reactivity in high and low altitude newborn lambs Galvez, P; Krause, B; Casanello, P; Herrera EA; Llanos, AJ Abstract PLACENTA (2006)
Differential regulation of adenosine transport by activation of A(2a) and A(1) purinoceptors in human umbilical vein endothelium Minaya, F; San Martín R.; Casanello, P; Sobrevia L. Abstract PLACENTA (2006)
Effect of insulin on L-arginine transport through system y(+)L in human umbilical vein endothelium Varas, J; Farias M.; Casanello, P; Sobrevia L. Abstract PLACENTA (2006)
Effects of insulin on the expression and activity of system y(+)L-mediated L-arginine transport in human umbilical vein endothelium Varas, J; Farias M.; Casanello, P; Sobrevia L. Abstract EARLY HUMAN DEVELOPMENT (2006)
Hemoxygenase expression in lung tissue from high and low altitude newborn lambs Martinez, G; Ebensperger G.; Krause, B; Casanello, P; Reyes, VR; Llanos, AJ Abstract PLACENTA (2006)
Hypoxia increases equilibrative nucleoside transporter 2 activity by a transcriptional independent mechanism in human umbilical vein endothelium Torres A.; San Martín R.; Farias M.; Sobrevia L.; Casanello, P Abstract PLACENTA (2006)
Hypoxia represses carbon monoxide/heme oxygenase (Co/Ho) system and downregulates L-arginine/nitric oxide (No) pathway in human umbilical vein endothelial cells (Huvec). Gallardo V.; Sobrevia L.; Casanello, P Abstract ISI Hypertension in Pregnancy (2006)
Hypoxia-induced heme oxygenase-1 regulates the L-arginine/nitric oxide pathway in human umbilical vein endothelium Gallardo V.; Sobrevia L.; Casanello, P Abstract ISI PLACENTA (2006)
Inhibition of L-arginine transport and nitric oxide activity in human umbilical vein endothelium of newborn with intrauterine growth restriction: role of hypoxia and PKC Casanello, P; Gallardo V.; Prieto, C; Sobrevia L. Abstract ISI EARLY HUMAN DEVELOPMENT (2006)
Insulin restores D-glucose reduced adenosine transport in human umbilical vein endothelium Muñoz G.; Casanello, P; Sobrevia L. Abstract ISI EARLY HUMAN DEVELOPMENT (2006)
Modulation of adenosine transport by insulin in human foetal endothelium Muñoz G.; Cea, L; Casanello, P; Sobrevia L. Abstract ISI PLACENTA (2006)
Post-translational modulation of equilibrative nucleoside transporter 1 by D-glucose in human umbilical vein endothelium Puebla, C; Casanello, P; Sobrevia L. Abstract ISI PLACENTA (2006)
Short-, but not long-term stimulation of L-arginine transport by D-glucose involves TGF-beta 1 in human foetal endothelium Vasquez R.; Casanello, P; Sobrevia L. Abstract ISI PLACENTA (2006)
Effect of transforming growth factor beta 1 on L-arginine/nitric oxide pathway in human umbilical vein endothelium exposed to high D-glucose Vasquez R.; Casanello, P; Sobrevia L. Abstract ISI PEDIATRIC RESEARCH (2005)
Equilibrative nucleoside transporter 1 is downregulated by activation of A(2a) adenosine receptors in human umbilical vein endothelium. Martin, RS; Minaya, F; Farias M.; Casanello, P; Sobrevia L. Abstract PEDIATRIC RESEARCH (2005)
Gestational diabetes increases L-arginine transport via a P13-K-independent mechanism in human foetal endothelium Gonzalez, M.; Casanello, P; Sobrevia L. Abstract ISI PEDIATRIC RESEARCH (2005)
Heme oxygenase 1 regulates the L-arginine/nitric oxide pathway in hypoxia in human umbilical vein endothelium Casanello, P; Sobrevia L.; Gallardo V. Abstract ISI PEDIATRIC RESEARCH (2005)
Insulin restores the elevated adenosine transport in human umbilical vein endothelial cells from intrauterine growth restriction pregnancies Sanhueza, F; Casanello, P; Sobrevia L. Abstract ISI PEDIATRIC RESEARCH (2005)
Role of nitric oxide in the pulmonary circulation in high- and low-altitude newborn lambs. Llanos, AJ; Sepulveda-Kattan, E; Riquelme R.; Herrera, E; Sanhueza E.; Ebensperger G.; Ebensperger, R; Reyes, VR; Pulgar VM; Casanello, P; Hanson, MA; Blanco, CE; Giussani, DA Abstract JOURNAL OF THE SOCIETY FOR GYNECOLOGIC INVESTIGATION (2005)
Expression of equilibrative nucleoside transporters 1 is modulated by hypoxia in human umbilical vein endothelial cells Torres A.; Aedo I.; Sanhueza, F; Gonzalez, M.; Casanello, P; Sobrevia L. Abstract ISI PLACENTA (2004)
Transforming growth factor beta 1 increases L-arginine transport and expression of the human cationic amino acid transporter 1 mRNA in human umbilical vein endothelial cells Vasquez R.; Gonzalez, M.; Casanello, P; Sobrevia L. Abstract ISI PLACENTA (2004)
Intra-uterine growth retardation is associated with reduced activity and expression of cationic amino acid transporters (system y(+)/CAT) and nitric oxide synthase in human umbilical vein endothelial cells Casanello, P; Sobrevia L. Abstract ISI JOURNAL OF PHYSIOLOGY-LONDON (2001)


Programación epigenética placentaria en restricción del crecimiento intrauterino Casanello, P; Castro-Rodríguez J.A.; Uauy R.; Krause, B. J. Actualizacion SCIELO SCOPUS Revista chilena de pediatría (2016)


Adenosine receptors: A novel therapeutic alternative for diabetic nephropathy San Martín R.; Roa, Horacio; Sobrevia L.; Sobrevia L.; Casanello, P BookSection (2011)
Multidrug Resistance Proteins Carcamo, JG; Quezada, CA; González-Oyarzún M.; Sobrevia L.; Casanello, P BookSection (2009)
Role of equilibrative nucleoside transporters in fetal endothelial dysfunction in gestational diabetes Sobrevia, Luis; Puebla, carlos; Farias, Marcelo; Casanello, Paola; Sobrevia, Luis; Casanello, Paola BookSection (2009)
Mecanismos moleculares asociados a la regulación del transporte y metabolismo de adenosina y L-arginina por hipoxia en endotelio fetal humano Casanello, Paola; Farias, Marcelo; Torres, Alberto; Sanhueza, Felipe; Sobrevia, Luis; Moraga, F; Pancetti F.; Vadulli, R; Jan Ryn, Z BookSection (2006)


Intervention Strategies for Preventing Low Birthweight in Developing Countries: Importance of Considering Multiple Interactive Factors Uauy R.; Corvalán C.; Casanello, P; Kuzanovic, J ConferencePaper ISI SCOPUS Nestle Nutrition Institute Workshop Series (2013)
Role of equilibrative nucleoside transporters in endothelial dysfunction: Adenosine/L-arginine/nitric oxide pathway Sobrevia L.; Farias M.; Vecchiola, A; Casanello, P ConferencePaper Acta Biomedica de l'Ateneo Parmense (2006)


Early origins of Allergy and Asthma Programa de Investigación Asociativa (PIA) Anillos ACT172097 (ACT172097) Proyecto 2018-2020 Inv. Principal
DOCOSAHEXAENOIC ACID (DHA) SUPPLEMENTATION DURING PREGNANCY TO PREVENT DEEP PLACENTATION DISORDERS=> A RANDOMIZED CLINICAL TRIAL AND A STUDY OF THE MOLECULAR PATHWAYS OF ABNORMAL PLACENTATION PREVENTION FONDECYT (1141207) Proyecto 2014-2018 Coinvestigador(a)
EARLY RISK OF ASTHMA IN CHILDREN EXPOSED TO IN-UTERO MATERNAL OBESITY. AN EPIGENETIC-MEDIATED PROGRAMMING OF IMMUNE FUNCTION FONDECYT (1141195) Proyecto 2014-2018 Coinvestigador(a)
EFFECTIVENESS OF A NORMATIVE INTERVENTION (DIET, PHYSICAL ACTIVITY AND BREASTFEEDING) ON MATERNAL NUTRITION AND OFFSPRING GROWTH AND DEVELOPMENT=> NUTRITION IN THE FIRST 1000 DAYS KEY TO HEALTHY GROWTH AND LONG-TERM HEALTH. FONDECYT (1130277) Proyecto 2013-2017 Coinvestigador(a)
MODELING THE EPIGENETIC PROGRAMMING OF VASCULAR DYSFUNCTION BY OXIDATIVE STRESS IN THE INTRAUTERINE GROWTH RESTRICTED FETUS=> ROLE OF PRENATAL ANTIOXIDANTS IN PREVENTING LONG-TERM VASCULAR DYSFUNCTION FONDECYT (1130801) Proyecto 2013-2017 Coinvestigador(a)
New pharmacologic formulation for the treatment and prevention of arterial hypertension and vascular dysfunction=> an integrated response to a multifactorial disease. FONDEF (D11/1098) Proyecto 2013-2016 Inv. Principal
INTRAUTERINE PROGRAMMING OF HIPOXIA- AND OXIDATIVE STRESS-INDUCED VASCULAR RESPONSES IN PLACENTAL ENDOTHELIUM FROM IUGR AND MACROSOMIC FETUSES=> EARLY EVIDENCE FOR EPIGENETIC-DRIVEN VASCULAR DYSFUNCTION. FONDECYT (1120928) Proyecto 2012-2016 Inv. Responsable
ROLE OF ADENOSINE IN INSULIN RESPONSE OF MACRO AND MICROVASCULAR HUMAN PLACENTAL ENDOTHELIUM FROM GESTATIONAL DIABETES MELLITUS VIA INSULIN RECEPTOR SUBTYPES A AND B. FONDECYT (1110977) Proyecto 2011-2015 Coinvestigador(a)
Caracterización de mecanismos fisiopatológicos y detección de blancos terapéuticos comunes en la disfunción placentaria en patologías del embarazo humano. (Investigador Principal Alterno) CONICYT (PIA- ANILLOS ACT73) Proyecto 2010-2013 Inv. Principal
ROL PARACRINO DEL PEPTIDO NATRIURETICO CEREBRAL (BNP) EN LA MANTENCION DE LA QUIESCENCIA MIOMETRIAL DEL EMBARAZO. ESTUDIO DE SUS VIAS DE SEQALIZACION CELULAR EN EL MIOMETRIO HUMANO FONDECYT (1090616) Proyecto 2009-2012 Coinvestigador(a)
PAPEL DE ARGINASAS I Y II EN LA DISFUNCION ENDOTELIAL DE LA UNIDAD FETO-PLACENTARIA EN EMBARAZOS CON RESTRICCION DEL CRECIMIENTO INTRAUTERINO Y EN HIPOXIA FONDECYT (1080534) Proyecto 2008-2012 Inv. Responsable
REGULACION DE LA EXPRESION Y ACTIVIDAD DE LOS TRANSPORTADORES EQUILIBRADOS DE NUCLEOSIDOS TIPO 1 (HENT1) Y 2 (HENT2) POR INSULINA EN EL ENDOTELIO MICRO Y MACROVASCULAR FETAL HUMANO EN DIABETES MELLITUS GESTACIONAL. FONDECYT (1070865) Proyecto 2007-2011 Coinvestigador(a)
EL ORIGEN FETAL DE LA HIPERREACTIVIDAD VASCULAR PULMONAR Y DE LA HIPERTENSION PULMONAR POSTNATAL. FONDECYT (1050479) Proyecto 2005-2009 Coinvestigador(a)
REGULACION DE LA RUTA DE SENALIZACION L-ARGINIA/OXIDO NITRICO EN ENDOTELIO DE VENA UMBILICAL DE FETOS CON RESTRICCION DEL CRECIMIENTO INTARUTERINO (RCIU) FONDECYT (7050030) Proyecto 2005-2006 Inv. Responsable
REGULACION DE LA RUTA DE SENALIZACION L-ARGINIA/OXIDO NITRICO EN ENDOTELIO DE VENA UMBILICAL DE FETOS CON RESTRICCION DEL CRECIMIENTO INTARUTERINO (RCIU) FONDECYT (7030109) Proyecto 2003-2004 Inv. Responsable
REGULACION DE LA RUTA DE SENALIZACION L-ARGININA/OXIDO NITRICO EN ENDOTELIO DE VENA UMBILICAL DE FETOS CON RESTRICCION DEL CRECIMIENTO INTRAUTERINO (RCIU) FONDECYT (1030607) Proyecto 2003-2007 Inv. Responsable
REGULACION TRANSCRIPCIONAL DEL TRANSPORTADOR EQUILIBRATIVO DE NUCLEOSIDOS ENT1 POR D-GLUCOSA EN ENDOTELIO HUMANO. FONDECYT (1030781) Proyecto 2003-2007 Coinvestigador(a)


Adipokines underlie the early origins of obesity and associated metabolic comorbidities in the offspring of women with pregestational obesity Arroyo-Jousse, V; Jaramillo A.; CastaÃ±o-Moreno E.; LÃ©pez M.; Carrasco-NegÃ¼e K.; Casanello P. Review ISI SCOPUS BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2020)
Endothelial heterogeneity in the umbilico-placental unit: DNA methylation as an innuendo of epigenetic diversity Casanello, P; Schneider D.; Herrera EA; Uauy R.; Krause, BJ Review ISI SCOPUS FRONTIERS IN PHARMACOLOGY (2014)
Long-Term Impact of Early Life Events on Physiology and Behaviour Boersma, GJ; Bale, TL; Casanello, P; Lara, HE; Lucion, AB; Suchecki, D; Tamashiro, KL Review ISI SCOPUS JOURNAL OF NEUROENDOCRINOLOGY (2014)
The placental pursuit for an adequate oxidant balance between the mother and the fetus Herrera EA; Krause, B; Ebensperger G.; Reyes,RV; Casanello, P; Parra-Cordero, M; Llanos, AJ Review ISI SCOPUS FRONTIERS IN PHARMACOLOGY (2014)
Fetoplacental Vascular Endothelial Dysfunction as an Early Phenomenon in the Programming of Human Adult Diseases in Subjects Born from Gestational Diabetes Mellitus or Obesity in Pregnancy Leiva A.; Pardo F.; Ramirez, MA; Farias M.; Casanello, P; Sobrevia L. Review ISI SCOPUS Experimental Diabetes Research (2011)
Role of nitric oxide in placental vascular development and function Krause, BJ; Hanson, MA; Casanello, P Review ISI SCOPUS Placenta (2011)
Equilibrative Nucleoside Transporters in Fetal Endothelial Dysfunction in Diabetes Mellitus and Hyperglycaemia Westermeier, F; Puebla, C; Vega, JL; Farias M.; Escudero, c; Casanello, P; Sobrevia L. Review CURRENT VASCULAR PHARMACOLOGY (2009)
Equilibrative nucleoside (ENTs) and cationic amino acid (CATs) transporters: Implications in foetal endothelial dysfunction in human pregnancy diseases Casanello, P; Escudero, c; Sobrevia L. Review ISI CURRENT VASCULAR PHARMACOLOGY (2007)

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Paola Casanello

Profesor Asociado

División de Obstetricia y Ginecología

Pontificia Universidad Católica de Chile

Santiago, Chile

LUIS SOBREVIA

Professor

Division of Obstetrics and Gynaecology

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

SANTIAGO, Chile

Bernardo Krause

Associate Professor

Insituto de Ciencias de la Salud

Universidad de O'Higgins

Rancagua, Chile

Marcelo Farias

Assistant Professor

Division of Obstetrics and Gynecology

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE, DEPARTAMENTO DE OBSTETRICIA

Santiago, Chile

Carlos Escudero

Full Professor

Basic Sciences Department

Universidad del Bio Bio

Chillan, Chile

Rody San Martín

Professor

Sciences Faculty

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

Andrea Leiva

Profesor Asociado

Facultad de Ciencias de la Salud

Universidad San Sebastián

Santiago, Chile

Emilio HERRERA

Full Professor

Faculty of Medicine, ICBM

Universidad de Chile

Santiago, Chile

Carlos Puebla

Profesor Asistente

Universidad de O'Higgins

Rancagua, Chile

Carlos Puebla

Assistant Professor

Universidad de O'Higgins

Santiago, Chile

Francisco Westermeier

Universidad de Chile

Santiago, Chile

Carlos Salomón

Academic

University of Concepcion

Concepcion, Chile

Enrique Guzman

Profesor Asistente

Bioquímica Clínica e Inmunología

Universidad de Concepción

Concepción, Chile

CATALINA PRIETO

Investigadora senior

Biología

Universidad de Chile

Santiago, Chile

ivo carrasco

Investigador

Universidad San Sebastián

Santiago, Chile

Fernando Abarzua

Assitant researcher

Universidad de La Frontera

Temuco, Chile

Fabian Pardo

Profesor titular

Escuela de Medicina

Universidad de Valparaiso

San Felipe, Chile

Luis Cea

Profesor programa teaching

Instituto de Ciencias Biomédicas

Universidad Autónoma de Chile

Santiago, Chile

Claudio Aguayo

Profesor Asociado

Bioquimica Clinica e Inmunologia

UNIVERSIDAD DE CONCEPCIÓN

Concepción, Chile

Camila Corvalan

Assistant Professor

UNIVERSIDAD DE CHILE, INTA

SANTIAGO, Chile

Carlos Flores

Researcher

Biology Lab

CENTRO DE ESTUDIOS CIENTÍFICOS (CECS)

Valdivia, Chile

Maria Garmendia

Academic

Institute of Nutrition and Food Technology (INTA)

UNIVERSIDAD DE CHILE

SANTIAGO, Chile

Juan Kusanovic

Jefe CIMAF

Obstetricia y Ginecología

SERV. DE SALUD METROPOLITANA SUR ORIENTE, HOSPITAL SOTERO DEL RIO

Santiago, Chile

Andrea Vecchiola

Profesor Asistente

Endocrinologia

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Claudia Quezada

Full Professor

Institute of Biochemistry and Microbiology

Universidad Austral de Chile

Valdivia, Chile

marcela araya

Profesor Asistente

Departamento de Promoción de la Salud de la Mujer y el Recién Nacido

UNIVERSIDAD DE CHILE

Santiago, Chile

Jorge Llanos

PROFESOR TITULAR

FISIOPATOLOGÍA

UNIVERSIDAD DE CHILE - FACULTAD DE MEDICINA

Santiago, Chile

German Ebensperger

PROFESOR ASISTENTE

INSTITUTO DE CIENCIAS BIOMEDICAS

UNIVERSIDAD DE CHILE - FACULTAD DE MEDICINA

Santiago, Chile

Sebastian San Martin

Profesor Titular

Anatomía

UNIVERSIDAD DE VALPARAISO

Valparaiso, Chile

Omar Porras

Associate professor

Lab. Biología Celular

UNIVERSIDAD DE CHILE

Santiago, Chile

Alejandro Yanez

Full professor

Faculty of Science

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

Arturo Borzutzky

Chief; Associate Professor

Department of Pediatric Infectious Diseases and Immunology

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Jose Castro

Profesor Asociado

Cardiologia y Neumologia Pediatrica

Pontificia Universidad Catolica de Chile

Santiago, Chile

carolina iturriaga

Sub Directora Laboratorio de inmunología y Alergia Traslacional UC

Pediatria

Pontificia Universidad Católica de Chile

santiago, Chile

Juan Carcamo

Profesor Titular

Instituto de Bioquímica y Microbiología

Universidad Austral de Chile

Valdivia, Chile

Rodrigo Iturriaga

Chairman of the Department of Physiology

Physiology

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

Rodrigo Del Rio

Assistant Professor

Physiology

Pontificia Universidad Católica de Chile

Santiago, Chile

Jose Luis Vega

Profesor Asociado

Biomedico

Universidad de Antofagasta

Antofagasta, Chile

MARCO RAMIREZ

Associate Professor

Universidad de Antofagasta

Antofagasta, Chile

Jorge Carvajal

Chief of Department

Obstetrics

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Katia Fernández

Académico - Profesor Asociado

Facultad de Salud y Odontología

Universidad Diego Portales

Santiago, Chile

Karina Carrasco

Coordinadora de Estudios Clínicos

Obstetricia

Pontificia Universidad Católica de Chile

Santiago, Chile

Víctor Reyes

Profesor Asociado

Instituto de Ciencias Biomédicas

UNIVERSIDAD DE CHILE - FACULTA DE MEDICINA

Santiago, Chile

Salesa Barja

Médico Nutrióloga pediátrica

Gastroenterología y Nutrición Pediátrica

Pontificia Universidad Católica de Chile

Santiago, Chile

Sebastián Alarcón

Profesor Asistente

Medicina y Ciencia

Universidad San Sebastián

Concepcion, Chile

Gareth Owen

Profesor Titular

Fisiologia

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Romulo Melo

Neurosurgeon

Department of Neurosurgery

Instituto de Neurocirugía Dr. Asenjo

Santiago, Chile

Carlos Oyarzún

Profesor Adjunto Asociado

Ciencias

Universidad Austral de Chile

Valdivia, Chile

Carolina Serrano

Profesor Asistente Ordinario

Pediatric Gastroenterology and Nutrition

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Fernando Moraga

Profesor Asociado

Ciencias Biomédicas

UNIVERSIDAD CATÓLICA DEL NORTE

Coquimbo, Chile

Floria Pancetti

Director de Departamento

Ciencias Biomédicas

UNIVERSIDAD CATOLICA DEL NORTE

Coquimbo, Chile

Marcela Flores

Encargada Unidad de Investigación

Salud

Corporación Municipal de Puente Alto

Santiago, Chile

Natalia Mendez

Profesor Auxiliar

UNIVERSIDAD AUSTRAL DE CHILE

valdivia, Chile

Caroll Hernández

Investigador Postdoctoral

Enfermedades Infecciosas e Inmunología Pediátrica

Pontificia Universidad Católica de Chile

Santiago , Chile

Julio Alarcón

Docente

Ciencias Básicas

UNIVERSIDAD DEL BÍO-BÍO

Chillan, Chile

Carlos Jara

Profesor adjunto

Universidad de Valparaíso

Reñaca, Chile

natalia rodriguez

Encargada de Programa de Prevencion y Control VIH/Sida e ITS, Servicio de Salud Ñuble

Direccion de Atención Primaria

Servicio de Salud Ñuble

Chillán, Chile

Fabián Vega

Investigador postdoctoral

Oftalmología

Universidad de Chile

Santiago, Chile

Maria Repetto

Profesor Titular

Center for Genetics and Genomics

FACULTAD DE MEDICINA CLINICA ALEMANA-UNIVERSIDAD DEL DESARROLLO

Santiago, Chile

Macarena Tejos

Trainee (PhD Student)

Pontificia Universidad Católica de Chile

Santiago, Chile

Luis Venegas

Bioquímico/investigador

Anatomía Patológica

Clínica Alemana de Santiago

Santiago, Chile

Maria Poli

Associate Professor

Pediatrics

Universidad del Desarrollo

Lo Barnechea, Chile

Liliana Lamperti

Vicedecana

UNIVERSIDAD DE CONCEPCIÓN, FACULTAD DE FARMACIA

Concepción, Chile

Carolina Cabalín

Investigadora

Pediatría

Pontificia Universidad Católica de Chile

Santiago, Chile

MARCELO CORNEJO

Académico

Biomédico

Universidad de Antofagasta

Antofagasta, Chile

Paola Cecilia Casanello Toledo

Líneas de Investigación

Educación

Ciencias Fisiológicas, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2007

Ciencias Fisiológicas, UNIVERSIDAD DE CONCEPCION. Chile, 2003

Matrona, UNIVERSIDAD DE CONCEPCION. Chile, 1996

Perinatología, UNIVERSIDAD DE CONCEPCION. Chile, 2000

Experiencia Académica

Profesor Asociado Full Time

Profesor Asociado Full Time

Instructor Full Time

Profesor Titular Full Time

Experiencia Profesional

Instructor Escuela de Medicina Part Time

Profesor Asistente Escuela de Medicina Full Time

Research Fellow Welcome Trust Full Time

Instructor Escuela de Medicina Full Time

Profesor Asistente Adjunto Escuela de Medicina Full Time

Profesor Asistente Escuela de Medicina Full Time

Formación de Capital Humano

Difusión y Transferencia

Premios y Distinciones

Mejor Investigador Junior 2012 de la Escuela de Medicina de la Pontificia Universidad Católica de Chile

Best poster presentation in DOHaD World Congress

Ex-alumna distinguida

Expositora en Congreso del Futuro, Comisión del Senado, Chile

Invitación reunión expertos OMS

DOHaD Directive Council member

Ciencia de Frontera

DOHaD Recognized Health Educator Award

Distinción Máxima Tesis Doctoral

Travel Award

Research Visit Award

Best presentation I Latin American Symposium on Maternal-Fetal interaction

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