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Natalia Andrea Mendez Caceres

Profesor Auxiliar

UNIVERSIDAD AUSTRAL DE CHILE

valdivia, Chile

Programación fetal, hipertensión, melatonina

Doctorado en Ciencias Médicas, UNIVERSIDAD AUSTRAL DE CHILE. Chile, 2016
Licenciatura en Ciencias Veterinarias , UNIVERSIDAD MAYOR. Chile, 2005
Médico Veterinario, UNIVERSIDAD MAYOR. Chile, 2006
Ciencias Biológicas, UNIVERSIDAD DE CHILE. Chile, 2010

Profesor Auxiliar Full Time

UNIVERSIDAD AUSTRAL DE CHILE

Medicina

Valdivia , Chile

2016 - At present

Médico Veterinario. Asistente de Investigación

Universidad de Chile

Chile

2007 - 2008
Medico Veterinario, Asistente de Investigación

Universidad Austral de Chile

Chile

2011 - 2012
Médico Veterinario. Asistente de Investigación

Universidad de Chile

Chile

2008 - 2010
Tesista ayudante

Universidad de Chile

Chile

2004 - 2006
Médico Veterinario. Asistente de Investigación

Universidad Austral de Chile

Chile

2011 - 2014
Profesor Auxiliar

Universidad Austral de Chile

Chile

2016 - At present
Integrante Subcomité Bioetica uso de Animales en Experimentación Other

Universidad Austral de Chile

Valdivia, Chile

2016 - At present


Dietary Potassium Downregulates Angiotensin-I Converting Enzyme, Renin, and Angiotensin Converting Enzyme 2 Vio, Carlos P; Gallardo, Pedro; Cespedes, Carlos; Salas, Daniela; Diaz-Elizondo, Jessica; Mendez, Natalia Article WOS FRONTIERS IN PHARMACOLOGY (2020)
Fetal Programming of Renal Dysfunction and High Blood Pressure by Chronodisruption Mendez, Natalia; Torres-Farfan, Claudia; Salazar, Esteban; Bascur, Pía; Bastidas, Carla; Vergara, Karina; Spichiger, Carlos; Halabi, Diego; Vio, Carlos P; Richter, Hans G. Article ISI SCOPUS FRONTIERS IN ENDOCRINOLOGY (2019)
Long-Term Effects of Altered Photoperiod During Pregnancy on Liver Gene Expression of the Progeny Pamela Carmona1,2 , Bárbara Pérez1 , Carlos Trujillo1,3 , Gabriel Espinosa1 , Fernando Miranda1 , Natalia Mendez4 , Claudia Torres-Farfan4 , Hans G. Richter4 , Karina Vergara4 , Priscilla Brebi2,5 and José Sarmiento1 Article WOS FRONTIERS IN PHYSIOLOGY (2019)
Role of clock genes in fibrinolysis regulation: Circadian disturbance and its effect on fibrinolytic activity Carmona Pamela, Mendez Natalia, Ili Carmen G Brebi Priscilla Article (2019)
Developmental Programming of Capuchin Monkey Adrenal Dysfunction by Gestational Chronodisruption Richter Hans G, Mendez Natalia; Abarzua-Catalan Lorena, Valenzuela Guillermo; Seron-Ferre Maria, and Torres-FarfanClaudia Article BioMed Research International (2018)
Gestational chronodisruption leads to persistent changes in the rat fetal and adult adrenal clock and function. Salazar, E R; Richter, H G; Spichiger, C; Mendez, N; Halabi, D; Vergara, K; Alonso, I P; Corvalán, F A; Azpeleta, C; Seron-Ferre, M; Torres-Farfan, C Article The Journal of physiology (2018)
Imbalance in renal vasoactive enzymes induced by mild hypoxia: Angiotensin-converting enzyme increases while neutral endopeptidase decreases Vio, CP; Salas, D; Cespedes, C; Diaz-Elizondo, J; Mendez, N; Alcayaga, J; Iturriaga, R. Article ISI Frontiers in Physiology (2018)
Deciphering the Function of the Blunt Circadian Rhythm of Melatonin in the Newborn Lamb: Impact on Adrenal and Heart Seron-Ferre, M; Torres-Farfan, C; Valenzuela, FJ; Castillo-Galan, S; Rojas, A; Mendez, N; Reynolds, H; Valenzuela, GJ; Llanos, AJ Article ISI SCOPUS Endocrinology (2017)
Deciphering the Function of the Blunt Circadian Rhythm of Melatonin in the Newborn Lamb: Impact on Adrenal and Heart. Seron-Ferre M, Torres-Farfan C, Valenzuela FJ, Castillo-Galan S, Rojas A, Mendez N, Reynolds H, Valenzuela GJ, Llanos AJ Article WOS ENDOCRINOLOGY (2017)
Gestational Chronodisruption Impairs Circadian Physiology in Rat Male Offspring, Increasing the Risk of Chronic Disease Mendez, Natalia; Halabi, Diego; Spichiger, Carlos; Salazar, Esteban R.; Vergara, Karina; Alonso-Vasquez, Pamela; Carmona, Pamela; Sarmiento, Jose M.; Richter, Hans G.; Seron-Ferre, Maria; Torres-Farfan, Claudia Article ISI SCOPUS ENDOCRINOLOGY (2016)
Gestation under chronic constant light leads to extensive gene expression changes in the fetal rat liver Spichiger, C; Torres-Farfan, C; Galdames, HA; Mendez, N; Alonso-Vazquez, P; Richter, HG Article PHYSIOLOGICAL GENOMICS (2015)
Environmental control of biological rhythms: effects on development, fertility and metabolism. Amaral, F G; Castrucci, A M; Cipolla-Neto, J; Poletini, M O; Mendez, N; Richter, H G; Sellix, M T Article Journal of neuroendocrinology (2014)
Gestational chronodisruption impairs hippocampal expression of NMDA receptor subunits Grin1b/Grin3a and spatial memory in the adult offspring. Vilches, Nelson; Spichiger, Carlos; Mendez, Natalia; Abarzua-Catalan, Lorena; Galdames, Hugo A; Hazlerigg, David G; Richter, Hans G; Torres-Farfan, Claudia Article PloS one (2014)
Impact of gestational chronodisruption on fetal cardiac genomics. Galdames, Hugo A; Torres-Farfan, Claudia; Spichiger, Carlos; Mendez, Natalia; Abarzua-Catalan, Lorena; Alonso-Vazquez, Pamela; Richter, Hans G Article Journal of molecular and cellular cardiology (2014)
Impact of Maternal Melatonin Suppression on Amount and Functionality of Brown Adipose Tissue (BAT) in the Newborn Sheep. Seron-Ferre, Maria; Reynolds, Henry; Mendez, Natalia Andrea; Mondaca, Mauricio; Valenzuela, Francisco; Ebensperger, Renato; Valenzuela, Guillermo J; Herrera, Emilio A; Llanos, Anibal J; Torres-Farfan, Claudia Article Frontiers in endocrinology (2014)
Circadian rhythms in the fetus. Serón-Ferré, María; Mendez, Natalia; Abarzua-Catalan, Lorena; Vilches, Nelson; Valenzuela, Francisco J; Reynolds, Henry E; Llanos, Aníbal J; Rojas, Auristela; Valenzuela, Guillermo J; Torres-Farfan, Claudia Article Molecular and cellular endocrinology (2012)
Timed Maternal Melatonin Treatment Reverses Circadian Disruption of the Fetal Adrenal Clock Imposed by Exposure to Constant Light Mendez, N.; Abarzua-Catalan, L; Vilches, N; Galdames H.A.; Spichiger, C.; Richter, H. G.; Valenzuela G.J.; Seron-Ferre, M; Torres-Farfan, C Article ISI SCOPUS PLOS ONE (2012)
Timed maternal melatonin treatment reverses circadian disruption of the fetal adrenal clock imposed by exposure to constant light. Mendez, Natalia; Abarzua-Catalan, Lorena; Vilches, Nelson; Galdames, Hugo A; Spichiger, Carlos; Richter, Hans G; Valenzuela, Guillermo J; Seron-Ferre, Maria; Torres-Farfan, Claudia Article PloS one (2012)
A Circadian Clock Entrained by Melatonin Is Ticking in the Rat Fetal Adrenal Torres-Farfan, C; Mendez, N.; Abarzua-Catalan, L; Vilches, N; Valenzuela GJ; Seron-Ferre, M Article ISI SCOPUS Endocrinology (2011)
Carbon monoxide: a novel pulmonary artery vasodilator in neonatal llamas of the Andean altiplano Herrera EA; Reyes,RV; Giussani, DA; Riquelme, RA; Sanhueza, EM; Ebensperger G.; Casanello, P; Mendez, N.; Ebensperger, R; Sepulveda-Kattan, E; Pulgar VM; Cabello, G; Blanco, CE; Hanson, MA; Parer, JT; Llanos, AJ Article ISI SCOPUS CARDIOVASCULAR RESEARCH (2008)
Circadian Cortisol Secretion and Circadian Adrenal Responses to ACTH Are Maintained in Dexamethasone Suppressed Capuchin Monkeys (Cebus Apella) Torres-Farfan C, Valenzuela FJ, Ebensperger R, Méndez N, Campino C, Richter HG, Valenzuela GJ, Serón-Ferré M. Article WOS AMERICAN JOURNAL OF PRIMATOLOGY (2008)
Clock Gene Expression in Adult Primate Suprachiasmatic Nuclei and Adrenal: Is the Adrenal a Peripheral Clock Responsive to Melatonin Valenzuela FJ, Torres-Farfan C, Richter HG, Mendez N, Campino C, Torrealba F, Valenzuela GJ, Serón-Ferré M. Article WOS ENDOCRINOLOGY (2008)


Differential prostaglandins (PGs) role in the pulmonary circulation in hich and low altitude newborn lambs during hypoxemia Mendez NA; Riquelme, RA; Herrera EA; Sanhueza, EM; Llanos, AJ Abstract ISI PLACENTA (2006)


Maternal melatonin supplementation during gestation prevents adult onset of metabolic disorders in the offspring gestated under chronodisruption Torres-Farfan, Claudia; Mendez, Natalia Proyecto (2019)
Developmental Programming of Cardiovascular Disease by Gestational Chronodisruption FONDECYT (11170245) Proyecto 2017-2020 Inv. Principal
“Mecanismos Fisiopatológicos de enfermedades crónicas del adulto impuestas por la alteración circadiana prenatal=> valor terapéutico del tratamiento con melatonina a la madre expuesta a turnos nocturnos durante la gestación” PIA (ACT 1116) Proyecto 2015-2016 Personal técnico y/o de apoyo
"Caracterización funcional del fenotipo cardiovascular de animales adultos gestados en alteración del fotoperiodo materno (Cronodisrupción materna)" PFCHA (21120472) Proyecto 2012-2015 Tesista
“Developmental programming of chronic disease in adult and aging individuals=> the role of maternal melatonin in the regulation of transcriptional and gene promoter activity” FONDECYT (1110220) Proyecto 2011-2014 Personal técnico y/o de apoyo
¿Es el feto de rata un reloj periférico de la madre sincronizado por la melatonina materna? FONDECYT (1080649) Proyecto 2008-2010 Tesista
“El sistema circadiano fetal=> ¿Una jerarquía de relojes periféricos circadianos coordinados por la melatonina materna?” FONDECYT (1080649) Proyecto 2008-2010 Personal técnico y/o de apoyo
“La exposición a la melatonina materna durante la gestación tiene un papel fundamental en la termogénesis del recién nacido. FONDECYT (1060766) Proyecto 2007-2009 Personal técnico y/o de apoyo
"Acción de la melatonina materna durante la gestación y su efecto sobre la hiperfunción postnatal de la glándula suprarrenal en primates" FONDECYT (1050833) Proyecto 2005-2007 Personal técnico y/o de apoyo
"Rol de prostaglandinas y endotelinas en la circulación pulmonar de corderos recién nacidos" FONDECYT (1010636) Proyecto 2003-2005 Tesista


In utero circadian changes; facing light pollution Torres-Farfan C.; Mendez N.; Ehrenfeld P.; Seron-Ferre M. Review SCOPUS Current Opinion in Physiology (2020)
Circadian rhythms in the fetus Seron-Ferre, M; Mendez, N.; Abarzua-Catalan, L; Vilches, N; Valenzuela F. J.; Reynolds H.E.; Llanos, A. J.; Rojas A.; Valenzuela G.J.; Torres-Farfan, C Review ISI SCOPUS Molecular and Cellular Endocrinology (2012)