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German Ebensperger Darrouy

PROFESOR ASISTENTE

UNIVERSIDAD DE CHILE - FACULTAD DE MEDICINA

Santiago, Chile

HIPOXIA FETAL Y NEONATAL (PERINATAL); FISIOLOGIA Y MEDICINA DE GRANDES ALTITUDES; FISIOPATOLOGIA VASCULAR; INFLAMACIÓN VASCULAR; CIRCULACIÓN PULMONAR; CANALES IONICOS; FUNCION Y REACTIVIDAD VASCULAR; FUNCION CARDIOPULMONAR; FETAL PROGRAMMING

Ciencias Biomedicas, UNIVERSIDAD DE CHILE. Chile, 2011
Bioquimico, UNIVERSIDAD DE CHILE. Chile, 2001

Profesor Asistente Full Time

UNIVERSIDAD DE CHILE

Medicina

SANTIAGO, Chile

2012 - At present

Ayudante de Investigacion Full Time

Laboratorio Dr. Roberto Reyes

Santiago, Chile

2002 - 2007
Asistente de Investigacion Full Time

Laboratorio Dr. Anibal Llanos

Santiago, Chile

2007 - 2012


Melatonin long-lasting beneficial effects on pulmonary vascular reactivity and redox balance in chronic hypoxic ovine neonates GonzalÃ©z-Candia A.; Candia A.A.; Figueroa E.G.; Feixes E.; Gonzalez-Candia C.; Aguilar S.A.; Ebensperger G.; Reyes, R. V.; Llanos, A. J.; Herrera, E. A. Article SCOPUS Journal of Pineal Research (2020)
Perinatal cardiopulmonary adaptation to the thin air of the Alto Andino by a native Altiplano dweller, the llama Reyes, Roberto, V; Herrera, Emilio A.; Ebensperger, Germán; Sanhueza, Emilia Miguela; Giussani, Dino A.; Llanos, Anibal J. Article Journal of Applied Physiology (2020)
Antenatal melatonin modulates an enhanced antioxidant/pro-oxidant ratio in pulmonary hypertensive newborn sheep. Gonzalez-Candia, Alejandro; Veliz, Marcelino; Carrasco-Pozo, Catalina; Castillo, Rodrigo L; Cárdenas, J Cesar; Ebensperger, Germán; Reyes, Roberto V; Llanos, Aníbal J; Herrera, Emilio A Article Redox biology (2019)
Effects of Melatonin on the Defense to Acute Hypoxia in Newborn Lambs Beñaldo, Felipe A.; Llanos, Aníbal J.; Araya-Quijada, Claudio; Rojas, Auristela; Gonzalez-Candia, Alejandro; Herrera, Emilio A; Ebensperger, Germán; Cabello, Gertrudis; Valenzuela, Guillermo J.; Serón-Ferré, María Article ISI SCOPUS FRONTIERS IN ENDOCRINOLOGY (2019)
Melatonin modulates the expression of pulmonary prostanoids Simón A. Aguilar; Pamela V. Arias; Ignacio Canquil; Germán Ebensperger; Aníbal J. Llanos; Roberto V. Reyes; Alejandro González-Candia ; Emilio A. Herrera Article ISI SCIELO SCOPUS REVISTA MEDICA DE CHILE (2019)
The role of nitric oxide signaling in pulmonary circulation of high- and low-altitude newborn sheep under basal and acute hypoxic conditions Herrera, Emilio A; Ebensperger, Germán; Hernández, Ismael; Sanhueza, Emilia M.; Llanos, Aníbal J.; Reyes, Roberto, V Article ISI SCOPUS Nitric Oxide (2019)
The role of nitric oxide signaling in pulmonary circulation of high- and low-altitude newborn sheep under basal and acute hypoxic conditions. Herrera, Emilio A; Ebensperger, Germán; Hernández, Ismael; Sanhueza, Emilia M; Llanos, Aníbal J; Reyes, Roberto V Article Nitric oxide => biology and chemistry (2019)
Melatonin Decreases Pulmonary Vascular Remodeling and Oxygen Sensitivity in Pulmonary Hypertensive Newborn Lambs. Astorga, Cristian R; González-Candia, Alejandro; Candia, Alejandro A; Figueroa, Esteban G; Cañas, Daniel; Ebensperger, Germán; Reyes, Roberto V; Llanos, Aníbal J; Herrera, Emilio A Article Frontiers in physiology (2018)
Melatonin Decreases Pulmonary Vascular Remodeling and Oxygen Sensitivity in Pulmonary Hypertensive Newborn Lambs. Astorga, Cristian R; González-Candia, Alejandro; Candia, Alejandro A; Figueroa, Esteban G; Cañas, Daniel; Ebensperger, Germán; Reyes, Roberto V; Llanos, Aníbal J; Herrera, Emilio A Article Frontiers in physiology (2018)
Plasmatic Concentrations of ADMA and Homocystein in Llama () and Regulation of Arginase Type II=> An Animal Resistent to the Development of Pulmonary Hypertension Induced by Hypoxia. López, Vasthi; Moraga, Fernando A; Llanos, Anibal J; Ebensperger, German; Taborda, María I; Uribe, Elena Article Frontiers in physiology (2018)
Plasmatic Concentrations of ADMA and Homocystein in Llama () and Regulation of Arginase Type II=> An Animal Resistent to the Development of Pulmonary Hypertension Induced by Hypoxia. López, Vasthi; Moraga, Fernando A; Llanos, Anibal J; Ebensperger, German; Taborda, María I; Uribe, Elena Article Frontiers in physiology (2018)
Revisiting the Role of TRP, Orai, and ASIC Channels in the Pulmonary Arterial Response to Hypoxia. Reyes, Roberto V; Castillo-Galán, Sebastián; Hernandez, Ismael; Herrera, Emilio A; Ebensperger, Germán; Llanos, Aníbal J Article Frontiers in physiology (2018)
Revisiting the Role of TRP, Orai, and ASIC Channels in the Pulmonary Arterial Response to Hypoxia. Reyes, Roberto V; Castillo-Galán, Sebastián; Hernandez, Ismael; Herrera, Emilio A; Ebensperger, Germán; Llanos, Aníbal J Article Frontiers in physiology (2018)
The role of nitric oxide in the cardiopulmonary response to hypoxia in highland and lowland newborn llamas. Reyes, Roberto V; Díaz, Marcela; Ebensperger, Germán; Herrera, Emilio A; Quezada, Sebastián A; Hernandez, Ismael; Sanhueza, Emilia M; Parer, Julian T; Giussani, Dino A; Llanos, Aníbal J Article The Journal of physiology (2018)
The role of nitric oxide in the cardiopulmonary response to hypoxia in highland and lowland newborn llamas. Reyes, Roberto V; Díaz, Marcela; Ebensperger, Germán; Herrera, Emilio A; Quezada, Sebastián A; Hernandez, Ismael; Sanhueza, Emilia M; Parer, Julian T; Giussani, Dino A; Llanos, Aníbal J Article The Journal of physiology (2018)
2-aminoethyldiphenylborinate modifies the pulmonary circulation in pulmonary hypertensive hewborn lambs with partial gestation at high altitude. Castillo-Galán S, Quezada S, Moraga F, Ebensperger G, Herrera EA, Beñaldo F, Hernandez I, Ebensperger R, Ramirez S, Llanos AJ, Reyes RV Article Am J Physiol Lung Cell Mol Physiol (2016)
2-Aminoethyldiphenylborinate modifies the pulmonary circulation in pulmonary hypertensive newborn lambs partially gestated at high altitude Castillo-Galan, S; Quezada, S; Moraga, F; Ebensperger, G; Herrera, EA; Benaldo, F; Hernandez, I; Ebensperger, R; Ramirez, S; Llanos, AJ; Reyes, RV Article ISI SCOPUS AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2016)
Cardiovascular function in term fetal sheep conceived, gestated and studied in the hypobaric hypoxia of the Andean altiplano Herrera EA; Rojas, RT; Krause, BJ; Ebensperger G.; Reyes,RV; Giussani, DA; Parer, JT; Llanos, AJ Article ISI SCOPUS JOURNAL OF PHYSIOLOGY-LONDON (2016)
Cardiovascular function in term fetal sheep conceived, gestated and studied in the hypobaric hypoxia of the Andean altiplano. Herrera, Emilio A; Rojas, Rodrigo T; Krause, Bernardo J; Ebensperger, Germán; Reyes, Roberto V; Giussani, Dino A; Parer, Julian T; Llanos, Aníbal J Article The Journal of physiology (2016)
Cardiovascular function in term fetal sheep conceived, gestated and studied in the hypobaric hypoxia of the Andean altiplano. Herrera EA, Rojas RT, Krause BJ, Ebensperger G, Reyes RV, Giussani DA, Parer JT, Llanos AJ Article J Physiol (London) (2016)
Potential adverse effects of antenatal melatonin as a treatment for intrauterine growth restriction: findings in pregnant sheep Gonzalez-Candia, A; Veliz, M; Araya, C; Quezada, S; Ebensperger, G; Seron-Ferre, M; Reyes, RV; Llanos, AJ; Herrera, EA Article ISI SCOPUS AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY (2016)
Potential adverse effects of antenatal melatonin as a treatment for intrauterine growth restriction: findings in pregnant sheep. González-Candia A, Veliz M, Araya C, Quezada S, Ebensperger G, Serón-Ferré M, Reyes RV, Llanos AJ, Herrera EA Article Am J Obstet Gynecol (2016)
Role of the RhoA/ROCK pathway in high-altitude associated neonatal pulmonary hypertension in lambs Lopez, Nandy C.; Ebensperger, German; Herrera, Emilio A.; Reyes, Roberto V.; Calaf, Gloria; Cabello, Gertrudis; Moraga, Fernando A.; Beñaldo, Felipe A.; Diaz, Marcela; Parer, Julian T.; Llanos, Anibal J. Article ISI SCOPUS AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2016)
Role of the RhoA/Rock pathway in high-altitude associated neonatal pulmonary hypertension in lambs. López NC, Ebensperger G, Herrera EA, Reyes RV, Calaf G, Cabello G, Moraga FA, Beñaldo FA, Díaz M, Parer JT, Llanos AJ Article Am J Physiol Regul Integr Comp Physiol (2016)
Melatonin reduces oxidative stress and improves vascular function in pulmonary hypertensive newborn sheep Torres, F; Gonzalez-Candia, A; Montt, C; Ebensperger G.; Chubretovic, M; Seron-Ferre, M; Reyes,RV; Llanos, AJ; Herrera EA Article ISI SCOPUS Journal of Pineal Research (2015)
Melatonin reduces oxidative stress and improves vascular function in pulmonary hypertensive newborn sheep. Torres, Flavio; González-Candia, Alejandro; Montt, Camilo; Ebensperger, Germán; Chubretovic, Magdalena; Serón-Ferré, María; Reyes, Roberto V; Llanos, Aníbal J; Herrera, Emilio A Article Journal of pineal research (2015)
Melatonin reduces oxidative stress and improves vascular function in pulmonary hypertensive newborn sheep. Torres, Flavio; González-Candia, Alejandro; Montt, Camilo; Ebensperger, Germán; Chubretovic, Magdalena; Serón-Ferré, María; Reyes, Roberto V; Llanos, Aníbal J; Herrera, Emilio A Article Journal of pineal research (2015)
Pharmacological approaches in either intermittent or permanent hypoxia: A tale of two exposures. Herrera, E A; Farías, J G; Ebensperger, G; Reyes, R V; Llanos, A J; Castillo, R L Article Pharmacological research : the official journal of the Italian Pharmacological Society (2015)
Pharmacological approaches in either intermittent or permanent hypoxia=> A tale of two exposures. Herrera, E A; Farías, J G; Ebensperger, G; Reyes, R V; Llanos, A J; Castillo, R L Article Pharmacological research (2015)
Melatonin improves cerebrovascular function and decreases oxidative stress in chronically hypoxic lambs Herrera, Emilio A; Macchiavello, Roberto; Montt, Camilo; Ebensperger, Germán; Díaz Marcela; Ramírez, Santiago; Parer, Julian T.; Serón-Ferré, María; Reyes, Roberto, V; Llanos, Anibal J. Article ISI SCOPUS JOURNAL OF PINEAL RESEARCH (2014)
Melatonin improves cerebrovascular function and decreases oxidative stress in chronically hypoxic lambs. Herrera, Emilio A; Macchiavello, Roberto; Montt, Camilo; Ebensperger, Germán; Díaz, Marcela; Ramírez, Santiago; Parer, Julian T; Serón-Ferré, María; Reyes, Roberto V; Llanos, Aníbal J Article Journal of pineal research (2014)
The placental pursuit for an adequate oxidant balance between the mother and the fetus. Emilio A Herrera , Bernardo J Krause, Germán Ebensperger, Roberto V. Reyes, Paola Casanello, Mauro Parra-Cordero and Anibal J. Llanos Article Frontiers in Pharmacology (2014)
Inhibition of rat carotid body glomus cells TASK-like channels by acute hypoxia is enhanced by chronic intermittent hypoxia Ortiz FC; Del Rio R.; Ebensperger G.; Reyes, VR; Alcayaga J.; Varas, R.; Iturriaga R. Article ISI SCOPUS Respiratory Physiology and Neurobiology (2013)
Inhibition of rat carotid body glomus cells TASK-like channels by acute hypoxia is enhanced by chronic intermittent hypoxia. Ortiz FC, Del Rio R, Ebensperger G, Reyes VR, Alcayaga J, Varas R, Iturriaga R. Article Respir Physiol Neurobiol. (2013)
Store-operated channels in the pulmonary circulation of high- and low-altitude neonatal lambs Parrau, D; Ebensperger G.; Herrera EA; Moraga, F; Riquelme, RA; Ulloa CE; Rojas, RT; Silva P.; Hernandez, I; Ferrada, j; Diaz M.; Parer, JT; Cabello, G; Llanos, AJ; Reyes,RV Article ISI SCOPUS American Journal of Physiology - Lung Cellular and Molecular Physiology (2013)
Store-operated channels in the pulmonary circulation of high- and low-altitude neonatal lambs. Parrau D, Ebensperger G, Herrera EA, Moraga F, Riquelme RA, Ulloa CE, Rojas RT, Silva P, Hernandez I, Ferrada J, Diaz M, Parer JT, Cabello G, Llanos AJ, Reyes RV. Article Am J Physiol Lung Cell Mol Physiol. (2013)
The heme oxygenase-carbon monoxide system in the regulation of cardiorespiratory function at high altitude. Llanos AJ, Ebensperger G, Herrera EA, Reyes RV, Cabello G, Díaz M, Giussani DA, Parer JT. Article Respir Physiol Neurobiol. (2012)
The Hypoxic Placenta Van Patot M.C.T.; Ebensperger G.; Gassmann M.; Llanos, A. J. Article ISI SCOPUS High Altitude Medicine and Biology (2012)
The hypoxic placenta. van Patot MC, Ebensperger G, Gassmann M, Llanos AJ. Article High Alt Med Biol. (2012)
Counterpoint: high altitude is not for the birds! Llanos AJ, Ebensperger G, Herrera EA, Reyes RV, Moraga FA, Parer JT, Giussani DA. Article J Appl Physiol. (2011)
COUNTERPOINT: HIGH ALTITUDE IS NOT FOR THE BIRDS! Llanos, AJ; Ebensperger G.; Herrera EA; Reyes,RV; Moraga, FA; Parer, JT; Giussani, DA Article ISI JOURNAL OF APPLIED PHYSIOLOGY (2011)
Fetal and postnatal pulmonary circulation in the Alto Andino Llanos, AJ; Ebensperger G.; Herrera EA; Reyes,RV; Pulgar VM; Seron-Ferre, M; Diaz M.; Parer, JT; Giussani, DA; Moraga, FA; Riquelme, RA Article ISI SCOPUS Placenta (2011)
Fetal and postnatal pulmonary circulation in the Alto Andino. Llanos AJ, Ebensperger G, Herrera EA, Reyes RV, Pulgar VM, Serón-Ferré M, Díaz M, Parer JT, Giussani DA, Moraga FA, Riquelme RA. Article Placenta (2011)
Last word on point:counterpoint: high altitude is/is not for the birds! Llanos AJ, Ebensperger G, Herrera EA, Reyes RV, Moraga FA, Parer JT, Giussani DA. Article J Appl Physiol. (2011)
Role of the alpha-adrenergic system in femoral vascular reactivity in neonatal llamas and sheep: a comparative study between highland and lowland species Moraga, FA; Reyes,RV; Herrera EA; Riquelme, RA; Ebensperger G.; Pulgar VM; Parer, JT; Giussani, DA; Llanos, AJ Article ISI SCOPUS American Journal of Physiology - Regulatory Integrative and Comparative Physiology (2011)
Role of the alpha-adrenergic system in femoral vascular reactivity in neonatal llamas and sheep: a comparative study between highland and lowland species. Moraga FA, Reyes RV, Herrera EA, Riquelme RA, Ebensperger G, Pulgar VM, Parer JT, Giussani DA, Llanos AJ. Article Am J Physiol Regul Integr Comp Physiol. (2011)
Long-term exposure to high-altitude chronic hypoxia during gestation induces neonatal pulmonary hypertension at sea level Herrera EA; Riquelme, RA; Ebensperger G.; Reyes,RV; Ulloa CE; Cabello, G; Krause, BJ; Parer, JT; Giussani, DA; Llanos, AJ Article ISI SCOPUS American Journal of Physiology - Regulatory Integrative and Comparative Physiology (2010)
Long-term exposure to high-altitude chronic hypoxia during gestation induces neonatal pulmonary hypertension at sea level. Herrera EA, Riquelme RA, Ebensperger G, Reyes RV, Ulloa CE, Cabello G, Krause BJ, Parer JT, Giussani DA, Llanos AJ. Article Am J Physiol Regul Integr Comp Physiol. (2010)
Carbon monoxide: a novel pulmonary artery vasodilator in neonatal llamas of the Andean altiplano Herrera EA; Reyes,RV; Giussani, DA; Riquelme, RA; Sanhueza, EM; Ebensperger G.; Casanello, P; Mendez, N.; Ebensperger, R; Sepulveda-Kattan, E; Pulgar VM; Cabello, G; Blanco, CE; Hanson, MA; Parer, JT; Llanos, AJ Article ISI SCOPUS CARDIOVASCULAR RESEARCH (2008)
Carbon monoxide: a novel pulmonary artery vasodilator in neonatal llamas of the Andean altiplano. Herrera EA, Reyes RV, Giussani DA, Riquelme RA, Sanhueza EM, Ebensperger G, Casanello P, Méndez N, Ebensperger R, Sepúlveda-Kattan E, Pulgar VM, Cabello G, Blanco CE, Hanson MA, Parer JT, Llanos AJ. Article Cardiovasc Res. (2008)
Sildenafil reverses hypoxic pulmonary hypertension in highland and lowland newborn sheep Herrera EA; Ebensperger G.; Krause, BJ; Riquelme, RA; Reyes,RV; Capetillo, M; Gonzalez S.; Parer, JT; Llanos, AJ Article ISI SCOPUS PEDIATRIC RESEARCH (2008)
Sildenafil reverses hypoxic pulmonary hypertension in highland and lowland newborn sheep. Herrera EA, Ebensperger G, Krause BJ, Riquelme RA, Reyes RV, Capetillo M, González S, Parer JT, Llanos AJ. Article Pediatr Res. (2008)
Evolving in thin air - Lessons from the llama fetus in the altiplano Llanos, AJ; Riquelme, RA; Herrera, EA; Ebensperger, G; Krause, B; Reyes, RV; Sanhueza, EA; Pulgar, VM; Behn, C; Cabello G.; Parer, JT; Giussani, DA; Blanco, CE; Hanson, MA Article RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY (2007)
Evolving in thin air - Lessons from the llama fetus in the altiplano Llanos, AJ; Riquelme, RA; Herrera EA; Ebensperger G.; Krause, B; Reyes,RV; Sanhueza, EA; Pulgar VM; Behn, C; Cabello, G; Parer, JT; Giussani, DA; Blanco, CE; Hanson, MA Article ISI SCOPUS RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY (2007)
High-altitude chronic hypoxia during gestation and after birth modifies cardiovascular responses in newborn sheep Herrera, EA; Pulgar, VM; Riquelme, RA; Sanhueza, EM; Reyes, RV; Ebensperger, G; Parer, JT; Valdez, EA; Giussani, DA; Blanco, CE; Hanson, MA; Llanos, AJ Article AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2007)
High-altitude chronic hypoxia during gestation and after birth modifies cardiovascular responses in newborn sheep Herrera EA; Pulgar VM; Riquelme, RA; Sanhueza, EM; Reyes,RV; Ebensperger G.; Parer, JT; Valdez, EA; Giussani, DA; Blanco, CE; Hanson, MA; Llanos, AJ Article ISI SCOPUS AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2007)
Fetal brain hypometabolism during prolonged hypoxaemia in the llama Ebensperger, G; Ebensperger, R; Herrera, EA; Riquelme, RA; Sanhueza, EM; Lesage, F; Marengo, JJ; Tejo, RI; Llanos, AJ; Reyes, RV Article JOURNAL OF PHYSIOLOGY-LONDON (2005)
Fetal brain hypometabolism during prolonged hypoxaemia in the llama Ebensperger G.; Ebensperger, R; Herrera EA; Riquelme, RA; Sanhueza, EM; Lesage F.; Marengo, JJ; Tejo, RI; Llanos, AJ; Reyes,RV Article ISI SCOPUS JOURNAL OF PHYSIOLOGY-LONDON (2005)
Analysis of molecular epidemiology of Chilean Salmonella enterica serotype enteritidis isolates by pulsed-field gel electrophoresis and bacteriophage typing Fernandez, J; Fica, A; Ebensperger G.; Calfullan, H; Prat S.; Fernandez A.; Alexandre, M; Heitmann I. Article ISI SCOPUS JOURNAL OF CLINICAL MICROBIOLOGY (2003)
Analysis of molecular epidemiology of Chilean Salmonella enterica serotype enteritidis isolates by pulsed-field gel electrophoresis and bacteriophage typing. Fernandez, Jorge; Fica, Alberto; Ebensperger, German; Calfullan, Hector; Prat, Soledad; Fernandez, Alda; Alexandre, Marcela; Heitmann, Ingrid Article Journal of clinical microbiology (2003)
Epidemiología molecular de un brote de infecciones por Streptococcus pyogenes en una unidad de quemados Fica C, Alberto; Fernández O, Jorge; Ebensperger D, Germán; Cona T, Erna; Galanti D, Andrea; Alonso M, Catalina; Ulloa F, María Teresa; Frola M, Ana María; Prat M, Soledad Article Revista médica de Chile (2003)
Molecular epidemiology of a Streptococcus pyogenes related nosocomial outbreak in a burn unit Fica, A; Fernandez, J; Ebensperger G.; Cona, E; Galanti A.; Alonso,C.; Ulloa, MT; Frola, AM; Prat S. Article ISI REVISTA MEDICA DE CHILE (2003)


TREATMENT WITH CINACIGUAT IMPROVED THE VASOACTIVE PROPERTIES OF LAMB SMALL PULMONARY ARTERIES Benaldo, FA; Araya-Quijada, C; Ebensperger, G; Guzman-Silva, CP; Castillo-Galan, S; Seron-Ferre, M; Herrera, EA; Reyes, RV; Moraga, F; Llanos, AJ Abstract ISI PLACENTA (2017)
SEA LEVEL POSTNATAL EXPOSURE MODIFIES THE PULMONARY ARTERIAL PRESSURE, REACTIVITY AND REMODELING IN NEONATAL LAMBS BORN IN HIGHLANDS Ebensperger G.; Santos, D; Aburto, C; Ramos M.; Araya C.; Hernandez, I; Moraga, FA; Herrera EA; Reyes,RV; Llanos, AJ Abstract ISI PEDIATRIC RESEARCH (2013)
Hemin Treatment Increases cGMP Role in the Regulation of Pulmonary Artery Tone in Newborn Lambs from the Andean Altiplano Ebensperger G.; Moraga, FA; Reyes,RV; Rojas, RT; Parer, JT; Llanos, AJ Abstract ISI REPRODUCTIVE SCIENCES (2011)
FETAL AND NEONATAL PULMONARY CIRCULATION IN THE ALTO ANDINO Llanos, AJ; Ebensperger G.; Herrera EA; Riquelme, RA; Reyes,RV Abstract ISI PLACENTA (2010)
Hemin Increases Pulmonary HO Protein Expression and Pulmonary CO Production in Newborn Lambs from the Andean Altiplano Ebensperger G.; Ulloa C.; Reyes,RV; Riquelme R.; Herrera EA; Parer, JT; Llanos, AJ Abstract ISI REPRODUCTIVE SCIENCES (2010)
Persistent pulmonary hypertension of the newborn even following transient exposure of the pregnancy to high altitude Herrera EA; Ebensperger G.; Riquelme, RA; Reyes,RV; Krause, BJ; Giussani, DA; Llanos, AJ Abstract ISI REPRODUCTIVE SCIENCES (2008)
Brain hypometabolism after 24h of hypoxemia in the llama fetus Ebensperger, R; Ebensperger G.; Herrera EA; Sanhueza, EM; Riquelme, RA; Lesage F.; Marengo, JJ; Tejo, RI; Llanos, AJ; Reyes, VR Abstract ISI PLACENTA (2006)
Carbon monoxide (CO): A key vasodilator in the pulmonary circulation in the llama neonate Herrera EA; Reyes, VR; Riquelme, RA; Sanhueza, EM; Ebensperger G.; Ebensperger, R; Casanello, P; Martinez, G; Llanos, AJ Abstract ISI PLACENTA (2006)
Cardiovascular responses to acute hypoxemia in low altitude(LA)and high altitude (HA) fetal sheep (FS) Ebensperger G.; Herrera EA; Ebensperger, R; Riquelme, RA; Sanhueza, EM; Krause, B; Galvez, P; Valdez, E; Llanos, AJ Abstract ISI PLACENTA (2006)
Hemoxygenase expression in lung tissue from high and low altitude newborn lambs Martinez, G; Ebensperger G.; Krause, B; Casanello, P; Reyes, VR; Llanos, AJ Abstract ISI PLACENTA (2006)
Regional changes of NaKATPase activity in the brain of the hypoxemic llama fetus Tejo, R; Ebensperger, R; Ebensperger G.; Herrera, E; Sanhueza E.; Riquelme R.; Llanos A.; Reyes, VR Abstract ISI PLACENTA (2006)
Nakatpase, temperature and ion channels in the fetal llama brain submitted to hypoxia. Reyes, R; Ebensperger, R; Ebensperger G.; Riquelme R.; Sanhueza E.; Marengo, J; Herrera, E; Parer, J; Lesage F.; Tejo, R; Llanos A. Abstract ISI JOURNAL OF THE SOCIETY FOR GYNECOLOGIC INVESTIGATION (2005)
Role of nitric oxide in the pulmonary circulation in high- and low-altitude newborn lambs. Llanos, AJ; Sepulveda-Kattan, E; Riquelme R.; Herrera, E; Sanhueza E.; Ebensperger G.; Ebensperger, R; Reyes, VR; Pulgar VM; Casanello, P; Hanson, MA; Blanco, CE; Giussani, DA Abstract ISI JOURNAL OF THE SOCIETY FOR GYNECOLOGIC INVESTIGATION (2005)
Chronic hypoxia decreases the soluble guanylate cyclase in the neonatal lung of lowland species. Ebensperger G.; Reyes, VR; Herrera EA; Pulgar VM; Riquelme, RA; Sanhueza, EM; Hanson, MA; Giussani, DA; Blanco, CE; Llanos, AJ Abstract ISI PEDIATRIC RESEARCH (2004)
Chronic hypoxia modifies the cardiovascular function and the arterial contractility in the neonatal sheep Herrera EA; Pulgar VM; Riquelme, RA; Sanhueza, EM; Reyes, VR; Ebensperger G.; Hanson, MA; Giussani, DA; Blanco, CE; Llanos, AJ Abstract ISI PEDIATRIC RESEARCH (2004)
Lambs born at high altitude have a blunted pituitary-adrenal axis response to acute hypoxia. Riquelme, RA; Herrera EA; Sanhueza, EM; Pulgar VM; Reyes, VR; Ebensperger G.; Parer, JT; Giussani, DA; Blanco, CE; Hanson, MA; Llanos, AJ Abstract ISI JOURNAL OF THE SOCIETY FOR GYNECOLOGIC INVESTIGATION (2004)


Last Word on Point:Counterpoint: High altitude is/is not for the birds! Llanos, A. J.; Ebensperger G.; Herrera, E. A.; Reyes, R. V.; Moraga F.A.; Parer J.T.; Giussani D.A. Letter ISI SCOPUS Journal of Applied Physiology (2011)


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AFTER YEARS OF "NO"TREATMENT, WE SEEK FOR YES TREATMENTS=> SOLUBLE AND PARTICULATE GUANYLYL CYCLASES COULD SAY YES TO TREAT PULMONARY ARTERIAL HYPERTENSION OF THE NEWBORN. FONDECYT (1140647) Proyecto 2014-2018 Coinvestigador(a)
HEME OXYGENASE INDUCTION BY HEMIN REDUCES LUNG INFLAMMATION, OXIDATIVE STRESS, PULMONARY VASCULAR PROLIFERATION AND PULMONARY ARTERIAL HYPERTENSION IN CHRONICALLY HYPOXIC NEONATES IN THE ANDEAN ALTIPLANO FONDECYT (1130424) Proyecto 2013-2016 Inv. Principal
Blockade of store operated channels and ryanodine receptors as a strategy to treat the neonatal pulmonary hypertension induced by chronic hypoxia FONDECYT (1120605) Proyecto 2012-2015 Coinvestigador(a)
DEL MAL GAS AL BUEN GAS. TRATAMIENTO DE LA HIPERTENSION ARTERIAL PULMONAR DEL RECIEN NACIDO CON MOLECULAS DADORAS DE MONOXIDO DE CARBONO E INDUCTORAS DE LA HEM-OXIGENASA-1. FONDECYT (1090355) Proyecto 2009-2012 Investigador(a)
Hemoxigenasa, monóxido de carbono y canales iónicos en la regulación de la circulación y remodelamiento pulmonar de recién nacidos de tierras bajas y altas FONDECYT (1080663) Proyecto 2008-2012 Personal técnico y/o de apoyo
El origen fetal de la hiperreactividad vascular pulmonar y de la hipertensión pulmonar postnatal FONDECYT (1050479) Proyecto 2005-2008 Personal técnico y/o de apoyo
Effects of chronic hypoxia on fetal cardiovascular and endocrine functions in the sheep Wellcome trust (CRIG 072256/2/03/2) Proyecto 2004-2006 Personal técnico y/o de apoyo
Hipometabolismo cerebral acoplado a menor expresión de canales iónicos con la hipoxia prolongada como estrategia adaptativa en un modelo tolerante a la hipoxia FONDECYT (1020599) Proyecto 2002-2005 Personal técnico y/o de apoyo
Adaptaciones fisiológicas y moleculares de la circulación pulmonar a la hipoxia en el recién nacido de llama, resultado de una historia de exposición a las grandes altitudes en el altiplano andino FONDECYT (1010636) Proyecto 2001-2004 Personal técnico y/o de apoyo


Pharmacological approaches in either intermittent or permanent hypoxia: A tale of two exposures Herrera EA; Farias, JG; Ebensperger G.; Reyes,RV; Llanos, AR; Castillo, RL Review ISI SCOPUS Pharmacological Research (2015)
The placental pursuit for an adequate oxidant balance between the mother and the fetus Herrera EA; Krause, B; Ebensperger G.; Reyes,RV; Casanello, P; Parra-Cordero, M; Llanos, AJ Review ISI SCOPUS FRONTIERS IN PHARMACOLOGY (2014)
The heme oxygenase-carbon monoxide system in the regulation of cardiorespiratory function at high altitude Llanos, A. J.; Ebensperger G.; Herrera, E. A.; Reyes, R. V.; Cabello, G; Diaz M.; Giussani D.A.; Parer J.T. Review ISI SCOPUS Respiratory Physiology and Neurobiology (2012)