Man

Javier Hernán Romero Parra

Profesor Asistente

Universidad de Chile

Santiago, Chile

Líneas de Investigación


Rational Design, Synthesis, Biological Evaluation and Structure-Activity Relationship study of novel Benzo[d]imidazoles and Benzo[b]thiophenes as agonists of the cannabinoid type 1 and 2 receptors.

Educación

  •  Químico Farmacéutico , PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2009
  •  Organic Chemistry, Medicinal Chemistry, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2015
  •  Diplomado en Docencia Universitaria , UNIVERSIDAD CATOLICA DEL NORTE. Chile, 2019

Experiencia Académica

  •   INVESTIGADOR Part Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Química

    Santiago , Chile

    2009 - 2017

  •   PROFESOR INSTRUCTOR ADJUNTO Part Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Química

    Santiago , Chile

    2014 - 2017

  •   DOCENTE Part Time

    UNIVERSIDAD ANDRES BELLO

    Medicina

    Viña del Mar , Chile

    2015 - 2017

  •   Profesor Asistente Full Time

    UNIVERSIDAD CATOLICA DEL NORTE

    Facultad de Ciencias

    Antofagasta, Chile

    2018 - 2019

  •   Profesor Asistente Full Time

    UNIVERSIDAD DE CHILE

    Facultad de Ciencias Químicas y Farmacéuticas

    Santtiago, Chile

    2019 - At present

Experiencia Profesional

  •   PROFESOR INSTRUCTOR ADJUNTO Part Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Santiago , Chile

    2014 - 2017

  •   DOCENTE Part Time

    UNIVERSIDAD ANDRES BELLO VIÑA DEL MAR

    Viña del Mar , Chile

    2015 - 2017

  •   DOCENTE Part Time

    Universidad Andrés Bello

    Santiago, Chile

    2015 - 2016

  •   Profesor Asistente Full Time

    UNIVERSIDAD CATOLICA DEL NORTE

    Antofagasta, Chile

    2018 - 2019

  •   Profesor Asistente Full Time

    Universidad de Chile

    Santiago, Chile

    2019 - At present


 

Article (26)

Chemical Fingerprinting, Aorta Endothelium Relaxation Effect, and Enzymatic Inhibition of Canelo (<i>Drimys winteri</i> J. R. Forst. & G. Forst, (D.C) A. Gray, Family Winteraceae) Fruits
Motifs in Natural Products as Useful Scaffolds to Obtain Novel Benzo[<i>d</i>]imidazole-Based Cannabinoid Type 2 (CB2) Receptor Agonists
Alkaloid Profiling, Anti-Enzymatic and Antiproliferative Activity of the Endemic Chilean Amaryllidaceae Phycella cyrtanthoides
Design of benzimidazoles, benzoxazoles, benzothiazoles and thiazolopyridines as leukotriene A4 hydrolase inhibitors through 3D-QSAR, docking and molecular dynamics
Phenolic Fingerprinting and Bioactivity Profiling of Extracts and Isolated Compounds from Gypothamnium pinifolium Phil.
Phenolic Profile, Antioxidant and Enzyme Inhibition Properties of the Chilean Endemic Plant Ovidia pillopillo (Gay) Meissner (Thymelaeaceae)
UHPLC-MS Metabolomic Fingerprinting, Antioxidant, and Enzyme Inhibition Activities of <i>Himantormia lugubris</i> from Antarctica
Analysis of Carotenoids in Haloarchaea Species from Atacama Saline Lakes by High Resolution UHPLC-Q-Orbitrap-Mass Spectrometry: Antioxidant Potential and Biological Effect on Cell Viability
UHPLC-MS Chemical Fingerprinting and Antioxidant, Antiproliferative, and Enzyme Inhibition Potential of <i>Gaultheria pumila</i> Berries
Chemical Fingerprinting and Biological Evaluation of the Endemic Chilean FruitGreigia sphacelata(Ruiz and Pav.) Regel (Bromeliaceae) by UHPLC-PDA-Orbitrap-Mass Spectrometry
Chemical Profiling, Antioxidant, Anticholinesterase, and Antiprotozoal Potentials of Artemisia copa Phil. (Asteraceae)
DARK Classics in Chemical Neuroscience: Heroin and Desomorphine
Metabolomic Analysis, Fast Isolation of Phenolic Compounds, and Evaluation of Biological Activities of the Bark From Weinmannia trichosperma Cav. (Cunoniaceae)
Passive Commuting and Higher Sedentary Time Is Associated with Vitamin D Deficiency in Adult and Older Women: Results from Chilean National Health Survey 2016-2017
Three-Dimensional Quantitative Structure-Activity Relationships (3D-QSAR) on a Series of Piperazine-Carboxamides Fatty Acid Amide Hydrolase (FAAH) Inhibitors as a Useful Tool for the Design of New Cannabinoid Ligands
Combined CoMFA and CoMSIA 3D-QSAR study of benzimidazole and benzothiophene derivatives with selective affinity for the CB2 cannabinoid receptor
Effect of alpha lipoic acid on leukotriene A(4) hydrolase
NADPH oxidase activity: Spectrophotometric determination of superoxide using pyrogallol red
Synthesis, binding assays, cytotoxic activity and docking studies of benzimidazole and benzothiophene derivatives with selective affinity for the CB2 cannabinoid receptor
A combined CoMFA and CoMSIA 3D-QSAR study of benzamide type antibacterial inhibitors of the FtsZ protein in drug-resistant Staphylococcus aureus
Design, Synthesis, Biological Evaluation and Binding Mode Modeling of Benzimidazole Derivatives Targeting the Cannabinoid Receptor Type 1
Benzo[b]thiophene dimerization: A promising experimental finding directed to the C-3 functionalization with aryl alcohols.
Design, Synthesis, Binding and Docking-Based 3D-QSAR Studies of 2-Pyridylbenzimidazoles-A New Family of High Affinity CB1 Cannabinoid Ligands
Synthesis and Docking of new (2-(2,5-dimethoxyphenyl)-1Hbenzo[ d]imidazol-1-yl)(aryl)methanone derivatives designed as novel cannabinoid CB1 receptor antagonists
Synthesis and docking of new benzimidazole derivates designed as novel and potent CB1 cannabinoid ligands.
Synthesis, characterization, and electrochemical studies of new 5-and 6-nitro N-acyl-1H-indazoles

BookSection (1)

Genome Editing and Protein Energy Malnutrition

Proyecto (3)

Rational Design, Synthesis, Biological Evaluation and Structure Activity Relationship study of novel Benzo[d]imidazoles and Benzo[b]thiophenes as agonists of the cannabinoid type 1 and 2 receptors.
SÍNTESIS, EVALUACIÓN BIOLÓGICA Y ANÁLISIS DE RELACIÓN ESTRUCTURA-ACTIVIDAD DE DERIVADOS DE ÁCIDO (BENZO[B]TIOFENIL/METOXI/METILÉNAMINO)ALQUIL/BENZOIL-OICO COMO INHIBIDORES DE LA LEUCOTRIENO A4 HIDROLASA HUMANA
SYNTHESIS AND STRUCTURE-ACTIVITY RELATIONSHIPS STUDIES OF NOVEL CB1 RECEPTOR LIGANDS.
25
Javier Romero

Profesor Asistente

Departamento de Química Orgánica y Fisicoquímica

Universidad de Chile

Santiago, Chile

8
JAIME MELLA

PROFESOR ADJUNTO

INSTITUTO DE QUIMICA Y BIOQUIMICA

UNIVERSIDAD DE VALPARAISO

VALPARAISO, Chile

6
Carlos Pessoa

Profesor Titular

Departamento de Farmacia

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

3
Ricardo Tapia

Full Professor

Organic Chemistry

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

2
Carlos Fernández

Académico

Biomédico

Universidad de Antofagasta

Antofagasta, Chile

2
María José Torres

Docente

Farmacia

Pontificia Universidad Católica de Chile

Santiago, Chile

2
Javier Echeverría

Profesor Asistente e Investigador

Departamento de Ciencias del Ambiente

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago de Chile, Chile

2
MARIO SIMIRGIOTIS

full professor

Facultad de Ciencias

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

2
Gonzalo Recabarren

Académico

Farmacia

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Marco Mellado

Profesor / Investigador

Facultad de Medicina y Ciencias de la Salud

Universidad Central de Chile

Santiago, Chile

1
Carlos Areche

ASSOCIATE PROFESSOR

CHEMISTRY

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Luis Venegas

Bioquímico/investigador

Anatomía Patológica

Clínica Alemana de Santiago

Santiago, Chile

1
Javiera Cortés

Estudiante de Doctorado

Instituto de Ingeniería Biológica y Médica

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Edgar Pastene

Profesor

Ciencias Básias

Universidad del Bío-Bío

Chillán, Chile

1
Carlos Cristi

Docente-Investigador Jerarquizado, Escuela de Educación Física.

Pontificia Universidad Catolica de Valparaiso

Viña del Mar, Chile

1
Daniela Millan

Academico investigador

Centro integrativo de biologia y quimica aplicada

Universidad Bernardo O'Higgins

Santiago, Chile

1
CLAUDIO PARRA

Profesor Asistente

Química Orgánica

Universidad de Concepción

Concepción, Chile

1
Adrian Paredes

Academico

Química

UNIVERSIDAD DE ANTOFAGASTA

Antofagasta, Chile

1
Alexandra Galetovic

Profesora Asociada

Biomédico

Universidad de Antofagasta

ANTOFAGASTA, Chile

1
Maria Larrazabal

Academico

Departamento Ciencias de los Alimentos y Nutricion

UNIVERSIDAD DE ANTOFAGASTA

ANTOFAGASTA, Chile

1
ANA ZÁRATE

investigadora

Químca-Física

Pontificia Universidad Católica de Chile

Santiago, Chile

1
HERNAN PESSOA

Profesor Asociado

Química Orgánica y Fisicoquímica

UNIVERSIDAD DE CHILE

SANTIAGO, Chile

1
Rossy Escobar

Profesor Académico Auxiliar

Facultad de Medicina

Universidad Católica del Maule

Talca, Chile

1
Carolina Cabalín

Investigadora

Pediatría

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Javier Campanini

Docente Investigador

Facultad de Medicina y Ciencia

Universidad San Sebastian

Puerto Montt, Chile

1
Angelica Fierro

Associate

Chemistry

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Gonzalo Cabrera

Academic

Cell and Molecular Biology

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

1
Clemente Palacios

Académico

Química y Farmacia

Universidad Arturo Prat

Iquique, Chile

1
Carlos Lagos

Profesor Asociado

FACULTAD DE MEDICINA Y CIENCIA

UNIVERSIDAD SAN SEBASTIÁN

SANTIAGO, Chile

1
Luisa Quesada

Docente e investigadora

Nutrición y Dietética

Universidad San Sebastián

Valdivia, Chile

1
Manuel Gacitúa

Profesor asistente

Departamento de Química de los Materiales

Universidad de Santiago de Chile

Santiago, Chile