Cristina Bertocchi
Assistant Professor
Pontificia Universidad Católica de Chile
Santiago, Chile
My research interest focuses on understanding the molecular basis and dynamics regulating complex physiological function, in particular how cells communicate, interact and sense mechanical stimuli, in homeostasis and cancer transformation.
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Lung Physiology, LEOPOLD FRANZENS UNIVERSITAT INNSBRUCK. Austria, 2008
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Biological Science, UNIVERSITA DEGLI STUDI DI MILANO. Italia, 2002
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PhD Full Time
LEOPOLD FRANZENS UNIVERSITAT INNSBRUCK
Innsbruck, Austria
2002 - 2008
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PostDoc Full Time
National University of Singapore
Mechanobiology Institute
Singapur
2011 - 2017
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Senior PostDoc Full Time
National University of Singapore
Mechanobiology Institute
Singapur
2017 - 2018
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Undergraduate student Full Time
UNIVERSITA DEGLI STUDI DI MILANO
Biological Science
Italia
2001 - 2002
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PostDoc Part Time
INNSBRUCK MEDICAL UNIVERSITY
Innsbruck, Austria
2009 - 2010
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Prof Assist. Full Time
Pontificia Univ Catolica de Chile
Chile
2018 - At present
Teaching:
Teaching as Titular of the Course
- BIO4033- Métodos de microscopía óptica, electrónica e inmunohistoquímica (Methods for optic and electron microscopy and immunohistochemistry) - Titular: Bertocchi C – Course for PhD students Physiology Programme – Pontificia Universidad Católica de Chile, August 2020 – Present
- BIO4233 – Bases celulares y moleculares de la regulación fisiológica – Titular: Bertocchi C – Course for PhD students Physiology Programme – Pontificia Universidad Católica de Chile, January 2020 – Present
- BIO141C - Biología de la Célula (Cell Biology) – Titular: Bertocchi C – Course for undergraduate
Pontificia Universidad Católica de Chile, August 2019 – Present
- BIO4016 - Unidad de Investigación II - PhD Physiology Programme
Pontificia Universidad Católica de Chile, November 2019
- “Good Cell Culture Practice” – Titular: Bertocchi C and Ravasio A. Lectures, practical demonstrations and mentoring for PhD students. Mechanobiology Institute, NUS, Singapore, 2013 to 2015.
Teaching as collaborating Professor
- BIO4417 - Curso de Verano Microscopía Óptica Avanzada – Titular: Eisner V. – UMA (unidad de microscopia avanzada) Pontificia Universidad Católica de Chile, January 2020
- IBM3102 - Advanced Topics in Biological and Medical Engineering II – Titular: Ravasio A - IIBM PhD Programme
Pontificia Universidad Católica de Chile, November 2019
- BIO4233 - Bases celulares y moleculares de la regulación fisiológica (Cellular and molecular basis of physiological regulation) – Titular: Morselli E. – Physiology PhD Programme
Pontificia Universidad Católica de Chile, March 2019
- IIQ3662 - Seminarios de Postgrado – Titular: Ramirez C and Egaña T – Engineering PhD Programme
Pontificia Universidad Católica de Chile, May 2019
- BIO4234 - Señalización para la fisiología y patofisiología (Signaling in Development) – Titular: Owen G - PhD Physiology Programme Pontificia Universidad Católica de Chile, November 2018
- BN6401 - Advanced Quantitative Fluorescence Microscopy – Titular: Kanchanawong P. - Course for undergraduate
Department of Bioengineering, Faculty of Engineering, National University of Singapore.
- BN4301 - Principles of Tissue Engineering – Titular: Yim E. - Course for undergraduate
Department of Bioengineering, Faculty of Engineering, National University of Singapore.
Supervision of students:
Name: Varina Aldana
Program: tesis de pregrado
Project title: LAMININA ES CONSTITUYENTE DE LA PARED DE LAS ESTRUCTURAS TUBULARES DE MÍMICA VASCULOGÉNICA EN CÁNCER
Role : Comité de tesi
Name: Gabriel Mingo
Program: PhD student
Project title: Rol de la matriz extracelular y mecanismo de formación de mímica vasculogénica in vitro en cáncer de ovario y cáncer de mama.
Role : Co-tutor (co-supervisor)
Name: Nuñez Muriel
Program: PhD student
Project title: Papel de la activación de neuropilina 1 en fibroblastos asociados al carcinoma sobre la infiltración intratumoral de linfocitos T citotóxicos
Role : Miembro comité
Name: Felipe Valle
Program: PhD student
Project title: Mecanosensibilidad en linfocitos B: rol en el posicionamiento y distribución lisosomal durante su activación
Role : Miembro comité
Name: Hill Charlotte
Program: PhD student
Project title: Role of Tim3/Gal-9 axis in Treg infiltration and T cell exhaustion on anti-PD1 immunotherapy in gastric cancer
Role : Coordinadora
Name: Francisco Pena
Program: undergrad student -Pregrado de Verano
Project title: Mechanical Roles of Vinculin/?-catenin interaction in Adherens junction
Role : Tutora
Name: Leslie Muñoz
Program: undergrad student -Pregrado de Verano
Project title: Mechanical roles of Vinculin/beta-catenin interaction in Adherens Junction
Role : Tutora
Before 2018:
PhD students
Name: Lisheng Xu (Nathan) year 2016
Program: Rotation Student (8weeks project)
Project title: Microfabrication and imaging of pillars coated with E-cadherin biomimetic substrate
Name: Leeba Ann Chacko year 2015
Program: Rotation Student (8weeks project)
Project title: YAP/TAZ regulation of cell-cell adhesion mechanical properties
Name: Shiwen Guo year 2015
Program: Rotation Student (8weeks project)
Project title: Force measurements of MDCK cells on Ecadherin biomimetic substrate by traction force microscopy
Name: Azita Gorji year 2015
Program: PhD thesis
Project title: Study the effect of SHP2 and PTP1B inhibition on Tyrosine phosphorylation of catenins and VE-cadherin
MD students
Name: Marianne Schmidt year 2008
Program: Research project
Project title: Inflammatory potential of uromodulin
Grants
- Year 2020 Concurso Anillos en Ciencia y Tecnología 2019. Project Title: ¨Multiscale mechanics and self-organizing processes in developing Systems¨ (Conicyt: ACT192015)
- Year 2019 Fondo Semilla (Interdisciplinary Research funding call 2018) - Pontificia Universidad Católica de Chile, Santiago de Chile. Project Title: ”Accessing cadherin clustering dynamics via gold nanopatterning”.
- Year 2011 Jubiläumsfonds der Oesterreichisches National Fund (OeNB) Austria. Project Title: “Charakterisierung und therapeutische Elimination von Mikropartikeln bei Patienten mit Sepsis” (Characterization and therapeutic elimination of microparticles in patients with severe sepsis and septic Shock).
- Year 2010 Tiroler Wissenschaftsfond (TWF) Austria- n.: D-151610-034-011. Project Title: “An epithelial-endothelial co-culture model to study the role of NOS in inflammatory processes”.
- Year 2008 Vasopharm Austria. Project title: “Mechanism of VAS203 Effects on Function of Human Renal Epithelial Cells”.
Invited seminars
- Invited seminar, July 2019, Hosted by Prof. A. Cavalcanti, Max Planck Institute, Heidelberg, Germany
- Invited seminar, February 2019, Yale-NUS, Singapore.
- Invited talk at Seminarios de departamento de Biología Celular y Molecular, March 2019, Pontificia Universidad Católica de Chile, Santiago de Chile
- Invited talk at Workshop DF y IIBM, 29th June 2018, Pontificia Universidad Católica de Chile, Santiago de Chile
- Invited talk at SMART (Singapore MIT alliance), hosted by Prof K. Van Vliet, January 2018, Singapore
- Invited speaker at the 3rd International Conference on Mechanobiology (ISMB2017), 11th-14th Dec, 2017, Singapore.
- Invited speaker at Superresolution Microscopy Workshop 2017 (SRM 2017), 21th-24th Nov, 2017, Singapore
- Invited talk hosted by Prof P. Dietl, Professor of Physiology, Chair Institute of General Physiology, University of Ulm. 29th November-1st December 2016 Ulm, Germany.
- Invited talk hosted by Prof P. Dietl, Professor of Physiology, Chair Institute of General Physiology, University of Ulm. 16th-19th December 2015 Ulm, Germany.
- Invited talk hosted by Prof P. Dietl, Professor of Physiology, Chair Institute of General Physiology - University of Ulm. 4th-5th April 2012 Ulm, Germany.
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Prize for an outstanding Poster
Biophysical Society
Singapur, 2016
Prize for an outstanding Poster at the “Mechanobiology of Disease Conference”, organized by the Biophysical Society (Singapore).
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Prize for an Outstanding Poster
“IntensivMedizin”
Austria, 2008
Prize for an Outstanding Poster at the medical congress “IntensivMedizin” Innsbruck (Austria).
Chapter 4: Scanning angle interference microscopy (SAIM): acquisition, analysis and biological applications |
Further Characterization of the Nematode IClnN2 Protein Reconstituted in Lipid Bilayers. |
Integrating Microfabrication into Biological Investigations: the Benefits of Interdisciplinarity |
MULTISCALE DYNAMICS AND ACTIVE MATTER PROCESSES REGULATE TENSIONAL HOMEOSTASIS OF CELLULAR AGGREGATES |
Accessing cadherin clustering dynamics via gold nanopatterning |
Multiscale mechanics and self-organizing processes in developing Systems |
An epithelial-endothelial co-culture model to study the role of NOS in inflammatory processes |
Charakterisierung und therapeutische Elimination von Mikropartikeln bei Patienten mit Sepsis |
Mechanism of VAS203 Effects on Function of Human Renal Epithelial Cells” |