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Paula Gabriela Slater Guzmán

Postdoctoral researcher

Pontificia Universidad Católica de Chile

Santiago, Chile

Líneas de Investigación


I am interested on the cytoskeleton and organelle dynamics (mitochondria) guiding neuronal development and regeneration; and in the understanding of the early processes orchestrating the spinal cord regeneration.

Educación

  •  Cellular and Molecular Biology, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2016
  •  Biochemist, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2011
  •  Biological Sciences, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2013

Experiencia Académica

  •   Adjunct Professor Other

    Universidad Autónoma

    Chemistry and Biochemistry

    Santiago, Chile

    2014 - 2014

  •   Adjunct Professor Other

    Universidad Finis Terrae

    Odontology

    Santiago, Chile

    2014 - 2016

Experiencia Profesional

  •   Postdoctoral researcher Full Time

    Boston College

    Brighton, Boston, Estados Unidos

    2016 - 2018

  •   Postdoctoral researcher Other

    Pontificia Universidad Católica de Chile

    Santiago, Chile

    2018 - At present

Formación de Capital Humano


2019. Research Mentor, PUC, Chile. Mentoring two undergraduate students (Direct mentor of the course BIO295, PUC)

2016 - 2018. Research Mentor, Boston College, USA. Mentored two undergraduate students

2011 - 2016. Research Mentor, PUC, Chile. Mentored two undergraduate students

2017 – 18. - Co-founder and co-chair of the Boston College Postdoctoral Association
• Generation of the Knowledge dissemination program to support postdoctoral fellow presentation in meetings
• Organization of a talk series to support postdoctoral trainee program


Difusión y Transferencia


Oral Presentations:
1) Slater PG, Magee A, Samuelson A, Lowery LA. XMAP215 is important for coordination between actin filaments and microtubules in embryonic neuronal growth cones. ASCB EMBO 2017 meeting. Subgroup X: Neuronal Cytoskeleton: A Complex Interplay of Cytoarchitecture and Dynamics. 2-6 December 2017, Philadelphia, USA.

2) Slater PG, Magee A, Samuelson A, Lowery LA. XMAP215 is important for the actin filament and microtubule cytoskeleton coordination in the axonal growth cone. Biology Department Retreat. Boston College, August 2017.

Seminars:
1) XMAP215 promueve interacción entre microtúbulos y filamentos de actina y participa en la guía del crecimiento del axón. Cellular and Molecular Department seminars, PUC, January 2019.

2) CRF-BP/CRF2?R interaction: a possible escort role for CRF-BP. Data Club, Biology department, Boston College, December 2016.

3) CRF binding protein facilitates the presence of CRF type 2? receptor on the cell surface. Professor Shan Sockanathan D Phil lab, Director of Neuroscience Graduate Admissions Dept of Neuroscience Johns Hopkins School of Medicine, October 2015.

Science outreach:
1) 2019. Speaker “Estudios Científicos mediante el uso de ranas”, Workshop PUC Family Day, July 2019, PUC.

2) 2011 – 2013. Nucleus Millenium in Stress and Addiction (NEDA).
Speaker at workshops: “Bases Científicas de la Drogadicción” in Colegio Bicentenario República de Brasil, Concepción, October 2013.
“La fiesta de la Neurosciencia” of Explora Conicyt, Santiago, October 2012.
“Bases Científicas de la Drogadicción” in Instituto Regional Federico Errázuriz, Santa Cruz, September 2011.


Premios y Distinciones

  •   Award for the best thesis of 2010-2011 of Biochemistry major students

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Chile, 2011

    Award assigned to the best student in presenting and defending the results obtained in the undergraduate thesis

  •   Best Biochemist graduated student to enter the Ph.D. program

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Chile, 2011

    Award for been the best Biochemist graduated student to enter the Ph.D. program

  •   2015 Trainee Professional Development Award for SfN annual meeting

    Society for Neuroscience and the Professional Development Committee

    Estados Unidos, 2015

    The Trainee Professional Development Award (TPDA) recognizes undergraduate and graduate students and postdoctoral fellows demonstrating scientific merit and excellence in research with the chance to present an abstract at a poster session, meet peers and network with senior scientists, and participate in learning opportunities at the annual meeting

  •   Best PhD thesis in Biological Sciences of 2015-2016

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Chile, 2016

    Award for the best PhD thesis in Biological Sciences of 2015-2016


 

Article (15)

CKAP5 enables formation of persistent actin bundles templated by dynamically instable microtubules
Cornifelin expression during<i> Xenopus</i><i> laevis</i> metamorphosis and in response to spinal cord injury
Analysis of the early response to spinal cord injury identified a key role for mTORC1 signaling in the activation of neural stem progenitor cells
Spinal Cord Transection In <i>Xenopus laevis</i> Tadpoles
Tau, XMAP215/Msps and Eb1 co-operate interdependently to regulate microtubule polymerisation and bundle formation in axons
Xenopus, a Model to Study Wound Healing and Regeneration: Experimental Approaches
Characterization of Xenopus laevis guanine deaminase reveals new insights for its expression and function in the embryonic kidney
XMAP215 promotes microtubule-F-actin interactions to regulate growth cone microtubules during axon guidance in Xenopus laevis
Molecular Modeling of Structures and Interaction of Human Corticotropin-Releasing Factor (CRF) Binding Protein and CRF Type-2 Receptor
Xenopus laevis as a model system to study cytoskeletal dynamics during axon pathfinding
Corticotropin-Releasing Factor Receptors and Their Interacting Proteins: Functional Consequences
Corticotropin-releasing factor type-2 receptor and corticotropin-releasing factor-binding protein coexist in rat ventral tegmental area nerve terminals originated in the lateral hypothalamic area
CRF binding protein facilitates the presence of CRF type 2 alpha receptor on the cell surface
Dopamine D-1 and corticotrophin-releasing hormone type-2 alpha receptors assemble into functionally interacting complexes in living cells
Frizzled-5 Receptor Is Involved in Neuronal Polarity and Morphogenesis of Hippocampal Neurons

Review (3)

Mitochondrial function in spinal cord injury and regeneration
Unraveling Axon Guidance during Axotomy and Regeneration
Adult Hippocampal Neurogenesis in Aging and Alzheimer's Disease
18
Paula Slater

Postdoctoral researcher

Biological Sciences

Pontificia Universidad Católica de Chile

Santiago, Chile

5
Katia Gysling

Professor

Cellular and Molecular Biology

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Carlos Lagos

Profesor Asociado

FACULTAD DE MEDICINA Y CIENCIA

UNIVERSIDAD SAN SEBASTIÁN

SANTIAGO, Chile

1
Valerie Ramirez

Senior Associate Scientist

Inflammation Research

Amgen

Thousand Oaks, Estados Unidos

1
Sebastián Gutiérrez

Investigador postdoctoral

Fundación Ciencia & Vida

Santiago, Chile

1
Nibaldo Inestrosa

Full Professor

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
María Andrés

Full Professor

Cellular and Molecular Biology

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Elías Blanco

Profesor Asistente

Biomédico

UNIVERSIDAD DE ANTOFAGASTA

Antofagasta, Chile

1
Jorge Campusano

Associate Professor

Cell & Molecular Biology

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Lorena Varela

Assistant Professor

Biological Sciences

Universidad Andres Bello

Santiago, Chile