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Aline . Carvalho da Silva Xavier

Assistant Professor

Universidad de Santiago de Chile

Región metropolitana, Chile

Líneas de Investigación


My research is with medical equipment that produces images to help diagnose diseases (ex. Mammography, Magnetic Resonance, Ultrasound). Research keywords: Biomedical Engineering; Medical Images; Radiology; Magnetic Resonance; Ultrasound.

Educación

  •  PhD in Engineering Sciences. Speciality: Biomedical Engineering (Nuclear Magnetic Resonance), PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2020
  •  Master in Energy and Nuclear Tecnologies. Speciality: Image Quality and Dosimetry (Digital Mammography) , Universidade Federal de Pernambuco . Brasil, 2015
  •  Biomedical Engineering, Universidade Federal de Pernambuco . Brasil, 2013

Experiencia Académica

  •   Tutora en Diplomado de Resonancia Magnetica Other

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Chile

    2019 - 2020

  •   Profesora Other

    Universidad de O'Higgins

    Chile

    2020 - 2021

  •   Assistent Professor Full Time

    UNIVERSIDAD DE SANTIAGO DE CHILE

    Faculty of Engineering

    Chile

    2022 - At present

Experiencia Profesional

  •   Service Provider (1 year and 3 months) Part Time

    Laboratório de Metrologia das Radiacões Ionizantes

    Brasil

    2014 - 2015

  •   Professional Internship (6 months) Full Time

    Centre Hospitalier Sainte Anne

    Francia

    2012 - 2012

  •   Professional Internship (5 months) Part Time

    Empresa Brasileira de Engenharia Médica

    Brasil

    2011 - 2011

  •   Research Student (two and a half years) Part Time

    Centro Regional de Ciencias Nucleares

    Brasil

    2009 - 2011

  •   Postdoctoral Researcher Full Time

    Universidad de O'Higgins

    Chile

    2020 - 2022

Formación de Capital Humano


1 alumna de magister y dos de pregrado


Difusión y Transferencia


He participado regularmente en las actividades de difusión y presentación de avances durante la ejecución del CONICYT-PIA Anillo ACT 141, Núcleo Milenio Cardio MR y actualmente del Instituto IHealth. También participé activamente en actividades de difusión de la ciencia a la comunidad, realizando seminarios a alumnos de 4to. Medio invitados a conocer la relación que hay entre Ingeniería, Medicina y Ciencias Biológicas.
Actualmente tengo videos en YouTube de mi investigación y contribuyo con contenido para instragram de los proyectos. Además, soy la representante de ingenieria biomédica (coordinadora) en el comité de vinculación con el medio de la USACH.


Premios y Distinciones

  •   First place banner presentation

    FACIPE

    Brasil, 2014

    III encontro científico de radiologia

  •   First place in master selection

    Universidade Federal de Pernambuco

    Brasil, 2013

    Before start the master in the universidade federal de pernambuco they make a selection of students and I earned the first palce

  •   Research Student Scholarship CNPq 117571&119253

    Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

    Brasil, 2009

    During two and a half years I had a scholarship from CNPq to perform research at Centro Regional de Ciencias Nucleares. 20h per week (01/2019 untill 07/2011).

  •   CAPES/BRAFITEC 3121\11-9 (Internship in France)

    CAPES\BRAFITEC

    Brasil, 2011

    INTERNSHIP I earned a scholarship to study in France for one year (Université de Technologie de Compiègne)

  •   FACEPE IBPG-0045-3.09\12 (Master degree)

    Fundação de Amparo a Ciência e Tecnologia de PE (FACEPE)

    Brasil, 2013

    Scholarship to do a Master at Federal University of Pernambuco (UFPE)

  •   CONICYT folio 21160835

    COMISION NACIONAL DE INVESTIGACION CIENTIFICA Y TECNOLOGICA

    Chile, 2016

    Scholarship to do the PhD at Pontificia Universidad Catolica de Chile

  •   FONDECYT PostDoc

    Universidad de O'Higgins

    Chile, 2021

    Proyecto de PostDoc 2021-2024 FONDECYT ANID 3210458


 

Article (14)

Exact Classification of NMR Spectra from NMR Signals
Characterization of hepatic fatty acids using magnetic resonance spectroscopy for the assessment of treatment response to metformin in an eNOS(-/-) mouse model of metabolic nonalcoholic fatty liver disease/nonalcoholic steatohepatitis
Characterization of hepatic fatty acids using magnetic resonance spectroscopy for the assessment of treatment response to metformin in an eNOS−/− mouse model of metabolic nonalcoholic fatty liver disease/nonalcoholic steatohepatitis
Characterization of Direct Localization Algorithms for Ultrasound Super-Resolution Imaging in a Multibubble Environment: A Numerical and Experimental Study
Assessment of hepatic fatty acids during non-alcoholic steatohepatitis progression using magnetic resonance spectroscopy
Comparison of localization methods in super-resolution imaging
Lipoprotein receptor SR-B1 deficiency enhances adipose tissue inflammation and reduces susceptibility to hepatic steatosis during diet-induced obesity in mice
Metabolite cycled liver H-1 MRS on a 7 T parallel transmit system
ESMRMB 2019, 36th Annual Scientific Meeting, Rotterdam, NL, October 3-October 5: Abstracts, Thursday
Intrahepatic fatty acids composition as a biomarker of NAFLD progression from steatosis to NASH by using H-1-MRS
Study on patient dosimetry and image quality in digital mammography
Dosimetric evaluation of X-ray examinations of paranasal sinuses in pediatric patients [Avaliação dosimétrica de pacientes pediátricos submetidos a exames radiográficos de seios paranasais]
Metodologia para calibração do detector de NaI(Tl) 3 x3 para medições in vivo em pacientes submetidos a radioiodoterapia e indivíduos ocupacionalmente expostos ao 131I.
Monitoração in vivo dos indivíduos ocupacionalmente expostos na produção de 18FDG no CRCN/NE

Abstract (1)

ANTIHYPERTENSIVE AND HYPOGLYCEMIC THERAPY REDUCES BODY AND LIVER FAT DEPOSITION IN A MURINE MODEL OF NON-ALCOHOLIC FATTY LIVER DISEASE (NAFLD)

ConferencePaper (30)

Liver fatty acids show gender-specific changes during MAFLD progression in eNOS KO mice.
Cálculo de los tiempos de relajación de metabolitos hepáticos utilizando espectroscopia por resonancia magnética de 9.4 Tesla
Cálculo de velocidad de flujo sanguíneo en microvasos a partir de imágenes de super-resolución de placentas ex – vivo
Magnetic resonance spectroscopy detects the progression of the MAFLD in eNOS KO mice, and it has a gender difference.
A clustering method to classify stages of NAFLD based on the metabolites results obtained in two mouse models with MRS
Classifying healthy versus NAFLD mice from liver fatty acids’ 1H- MRS at 9.4 T using SVMs
Super-Resolution Ultrasound Imaging: a Comparison Between Localization Methods
Fatty acids and cholesterol peaks found in MRS are biomarkers of Niemann-Pick C disease diagnosis
The use of magnetic resonance spectroscopy and principal component analysis in order to identify the progression of NAFLD
Ex vivo quantification of hepatic fatty acid in mice fed with western-diet using magnetic resonance spectroscopy at 9.4 T
Hepatic Fatty Acid Profile in Mice with Nonalcoholic Fatty Liver Disease Using Magnetic Resonance Spectroscopy
Implementation of metabolite cycled liver 1H MRS on a 7T parallel transmit system.
In vivo and ex vivo quantification of hepatic fatty acid in mice fed with CDAA-diet using magnetic resonance spectroscopy at 9.4 T
In vivo liver pH in eNOS2/2 mice model fed with High Fat Diet may provide clues to understand their susceptible to develop NAFLD
Lipids composition of visceral fat in overweight and obese patients using 1H NMR at 9.4T
Towards glycoCEST in the liver at 7T with a multi-transmit system.
Cholesterol peaks found in MRS are a biomarker of Niemann-Pick disease progression
eNOS-/- mice fed with HFD develop progressive non-alcoholic fatty liver disease (NAFLD) which is partially reversible with antihypertensive and hypoglycemic therapy
Fatty acids profile during Non Alcoholic Fat Liver Disease progression using Magnetic Resonance Spectroscopy
Liver Cholesterol is a biomarker of Niemann-pick diseases progression and liver damage and could be quantified with MRS
Perfil de ácidos grasos en injertos hepáticos y renales en un modelo murino de muerte encefálica
Dosimetria de pacientes pediátricos submetidos a exames radiológicos de seios da face.
Patient dosimetry in digital mammography in brazil and costa rica
Avaliação da dose glandular média em sistemas digitais e convencionais de mamografia
Dosimetria em exames de mamografia em Recife
Estimativa do produto erma no ar-area e do erma no ar na superfície de entrada da pele de pacientes pediátricos submetidos à radiografia do tórax
Monitoraçlão in vivo dos Indivíduos Ocupacionalmente Expostos ao 18FDG no CRCN/NE
Otimização da Metodologia de Monitoração Interna de 18F na Forma de 18FDG Desenvolvida no CRCN-NE.
Otimização da MetodoMetodologia para calibração do detector de NaI(TI) 3 x 3 para medições IN VIVO em pacientes submetidos a Iodoterapia e indivíduos ocupacionalmente expostos ao 131Ilogia de Monitoração Interna de 18F na Forma de 18FDG Desenvolvida no CRCN-NE.
Qualidade de imagem e dose para diferentes combinações tela-filme em mamografia

Proyecto (11)

Redes capilares, desprendimiento de geles en prótesis y fractura en minería de roca desde el punto de vista del análisis matemático de problemas de discontinuidad libre
INSTITUTO MILENIO EN INGENIERÍA E INTELIGENCIA ARTIFICIAL PARA LA SALUD iHEALTH
Realidad de las mujeres en las ciencias de la ingeniería en la región de O'higgins
Creacion de imagenes de super-resolucion ultrasonicas en placentas humanas ex vivo
Optimizing microbubbles localization in ultrasound super-resolution imaging
NÚCLEO MILENIO DE RESONANCIA MAGNÉTICA CARDIOVASCULAR
Anillo ACT1416 “Magnetic Resonance Imaging for Aging Related Diseases: Brain, Heart and Vessels”
FATTY ACIDS CHARACTERIZATION DURING NON-ALCOHOLIC FATTY LIVER DISEASE USING MAGNETIC RESONANCE SPECTROSCOPY
Dosimetría y Calidad de Imagen en Mamografía Digital.
Cálculo de la dosis para las pacientes con cáncer de tiroides a través de un estudio anatómico de la tiroides.
Control de la calidad en radiología convencional.
53
Aline Carvalho da Silva

Assistant Professor

Universidad de Santiago de Chile

Región metropolitana, Chile

4
Marcelo Andia

Associate Professor

Radiology

Pontificia Universidad Catolica de Chile

Santiago, Chile

3
Flavia Zacconi

Associate Professor

Organic Chemistry

Pontificia Universidad Católica de Chile

Santiago, Chile

2
Carlos Sing-Long

Assistant Professor

Instituto de Ingeniería Matemática y Computacional

Pontificia Universidad Católica de Chile

Santiago, Chile

2
Daniel Cabrera

Investigador Adjunto

Gastroenterología

Pontificia Universidad Catolica de Chile

santiago, Chile

2
Sergio Uribe

Associated professor

Radiology

PONTIFICIA UNIVERSIDAD CATÓLICA

Santiago, Chile

1
MARCO ARRESE

FULL PROFESSOR

GASTROENTEROLOGY

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile