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Pablo Andrés Castro Córdova

Investigador Postdoctoral

Universidad de Los Andes

Santiago, Chile

Líneas de Investigación


Improving immune cell metabolism to enhance cancer immunotherapy

Educación

  •  Ingeniero en Biotecnología, Universidad Andrés Bello. Chile, 2016
  •  Licenciatura en Biotecnología, Universidad Andrés Bello. Chile, 2014
  •  Doctorado en Biotecnología, Universidad Andrés Bello. Chile, 2020
  •  Biotecnología, Universidad Andrés Bello. Chile, 2016

Experiencia Académica

  •   Docente Part Time

    Universidad Andrés Bello

    Ciencias de la Vida

    Santiago, Chile

    2014 - 2015

Experiencia Profesional

  •   Personal técnico y/o de apoyo - FONDEF CA13I10077 Full Time

    Universidad Andrés Bello

    Santiago, Chile

    2015 - 2016

  •   Tesista pregrado/magister - FONDECYT REGULAR 1151025 Full Time

    Universidad Andrés Bello

    Santiago, Chile

    2014 - 2015

  •   Investigador - FONDEF IDEA ID16|10038 Part Time

    Universidad Andrés Bello

    Santiago, Chile

    2017 - 2018

  •   Investigador Joven - NCN17_093 - Núcleo Milenio Biología de Microbiota Intestinal Full Time

    Universidad Andrés Bello

    Santiago, Chile

    2021 - 2021

  •   Director alterno - NCN17_093 -Núcleo Milenio Biología de Microbiota Intestinal Full Time

    Universidad Andrés Bello

    Santiago, Chile

    2021 - 2022

  •   Investigador Postdoctoral Full Time

    Universidad de los Andes

    Santiago, Chile

    2022 - At present

Formación de Capital Humano


Tesis Director
2023
-Sebastian Valdes Universidad Andrés Bello - Ingeniería en Biotecnología

2024-actually
-Isidora Torres - Universidad Mayor - Biotecnología
-Catalina Marcos - Universidad Mayor - Biotecnología

2025-ongoing
-Maximiliano Hofmann - Ingeniería Civil Informática - Ingeniería Civil Bioingeniería - Universidad Adolfo Ibañez.


Premios y Distinciones

  •   Mejor graduado

    UNIVERSIDAD ANDRES BELLO

    Chile, 2020

    Premio al mejor graduado 2020 de Programas de Doctorado Universidad Andrés Bello. Vicerrectoría de Investigación y Doctorado

  •   Excelencia Académica

    UNIVERSIDAD ANDRES BELLO

    Chile, 2017

    Premio a la Excelencia Académica en el programa de Ingeniería en Biotecnología año 2017


 

Article (13)

Survival advantage of native and engineered T cells is acquired by mitochondrial transfer from mesenchymal stem cells
Editorial: Mechanism of colonization and persistence of gut commensal microbiota and pathogens
Redistribution of the Novel Clostridioides difficile Spore Adherence Receptor E-Cadherin by TcdA and TcdB Increases Spore Binding to Adherens Junctions
Entry of spores into intestinal epithelial cells contributes to recurrence of <i>Clostridioides difficile</i> infection
Using a ligate intestinal loop mouse model to investigate <i>Clostridioides difficile</i> adherence to the intestinal mucosa in aged mice
Effect of antibiotic to induce Clostridioides difficile-susceptibility and infectious strain in a mouse model of Clostridioides difficile infection and recurrence
Induction of a Specific Humoral Immune Response by Nasal Delivery of Bcla2(ctd) of Clostridioides difficile
Clostridium difficile exosporium cysteine-rich proteins are essential for the morphogenesis of the exosporium layer, spore resistance, and affect C. difficile pathogenesis
Indomethacin increases severity of Clostridium difficile infection in mouse model
Characterization of the Adherence of Clostridium difficile Spores=> The Integrity of the Outermost Layer Affects Adherence Properties of Spores of the Epidemic Strain R20291 to Components of the Intestinal Mucosa
Ultrastructural Variability of the Exosporium Layer of Clostridium difficile Spores
Outcome of relapsing Clostridium difficile infections do not correlate with virulence-, spore- and vegetative cell-associated phenotypes
Protein composition of the outermost exosporium-like layer of Clostridium difficile 630 spores

Correction (1)

Entry of spores into intestinal epithelial cells contributes to recurrence of <i>Clostridioides difficile</i> infection (vol 12, 1140, 2021)

Patent (2)

Method and pharmacological composition for the prevention of recurrent infections caused by Clostridium difficile
Composition based on nystatin and vancomycin nanoparticles for the treatment of Clostridioides difficile infection and prevention of recurrence
1
Fernando Gil

Professor

Centro de Investigación e Innovación Biomédica

Universidad de Los Andes

Santiago, Chile

1
IVAN CALDERON

Associate Professor / Principal Investigator/ Master in Biotechnology & Life Sciences Director

Biological Sciences

UNIVERSIDAD ANDRÉS BELLO

SANTIAGO, Chile

2
Daniel Paredes

Associate Professor

Department of Biological Sciences

Universidad Andrés Bello

Santiago, Chile

1
Manuel Alvarez

Gastroenterologist and Chief of Institute of Medicine

Gastroenterology

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Marjorie Pizarro

Asistente de Investigacion

Ciencias Biológicas

Universidad Andrés Bello

Santiago, Chile

1
Juan Fuentes

Académico

Ciencias Biológicas

Universidad Andrés Bello

Santiago, Chile

1
Cristian Hernández

Assistant Professor

Gastroenterology

Pontificia Universidad Católica de Chile

Santiago, Chile

2
Paulina Calderón

Investigador Principal

Biome Therapeutics

Santiago, Chile

1
Angela Plaza

Postodoctorado

Ingeniería Civile en Obras Civil

Universidad de Santiago de Chile

Estación Central, Chile

1
Enzo Guerrero

PhD Student

Universidad Andrés Bello

Santiago, Chile

2
Maria Mendoza

PhD. Candidat

Ciencias de la Vida

Universidad Andrés Bello

Santiago, Chile

3
Valeria Olguín

Lab Manager

Universidad del Desarrollo

Santiago, Chile

2
Juan Muñoz

Investigador I+D

I+D

Exacta BioScience

Rengo, Chile

15
Pablo Castro

Investigador Postdoctoral

Universidad de Los Andes

Santiago, Chile

1
Fernando Díaz

Investigador Doctoral

Universidad San Sebastián

Santiago, Chile