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Paulina Francisca Calderón Romero

Investigador Principal

Biome Therapeutics

Santiago, Chile

Microbioma intestinal humano, metodologías microbiológicas para estudiar la modificación de la microbiota intestinal. Genética bacteriana, cultivos bacterianos anaerobios estrictos. Microscopía de epifluorescencia.

Biociencias Moleculares, UNIVERSIDAD ANDRES BELLO. Chile, 2020
Bioquimica, UNIVERSIDAD ANDRES BELLO. Chile, 2014
Bioquimico, UNIVERSIDAD ANDRES BELLO. Chile, 2014

Profesor honorario Part Time

UNIVERSIDAD ANDRES BELLO

Ciencias Biológicas

Santiago, Chile

2013 - 2013

Investigadora Principal Full Time

Biome Therapeutics

Santiago, Chile

2019 - At present


Clostridium difficile exosporium cysteine-rich proteins are essential for the morphogenesis of the exosporium layer, spore resistance, and affect C. difficile pathogenesis Calderon-Romero, P; Castro-Cordova, P; Reyes-Ramirez, R; Milano-Cespedes, M; Guerrero-Araya, E; Pizarro-Guajardo, M; Olguin-Araneda, V; Gil, F; Paredes-Sabja, D Article ISI SCOPUS PLOS PATHOGENS (2018)
Updates on Clostridium difficile spore biology Gil, Fernando; Lagos-Moraga, Sebastián; Calderón-Romero, Paulina; Pizarro-Guajardo, Marjorie; Paredes-Sabja, Daniel Article ISI SCOPUS ANAEROBE (2017)
Ultrastructural Variability of the Exosporium Layer of Clostridium difficile Spores Pizarro-Guajardo, M; Calderón-Romero P.; Castro-Córdova P; Mora-Uribe, P; Paredes-Sabja D. Article ISI SCOPUS APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2016)
Ultrastructure Variability of the Exosporium Layer of Clostridium difficile Spores from Sporulating Cultures and Biofilms Pizarro-Guajardo, Marjorie; Calderón-Romero, Paulina; Paredes-Sabja, Daniel Article ISI SCOPUS APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2016)
Hydrogen peroxide and hypochlorous acid influx through the major S. Typhimurium porin OmpD is affected by substitution of key residues of the channel Aguayo, D; Pacheco N.; Morales E.H; Collao B; Luraschi, R.; Cabezas, C.; Calderon, P; Gonzalez-Nilo, F; Gil, F; Calderon I.L.; Saavedra, C. P. Article ISI SCOPUS ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2015)
Motility modulation by the small non-coding RNA SroC in Salmonella Typhimurium Fuentes, DN; Calderon, PF; Acuña LG; Rodas, PI; Paredes Sabja D; Fuentes, JA.; Gil, F; Calderon, IL Article ISI SCOPUS FEMS Microbiology Letters (2015)
Microarray analysis of the Escherichia coli response to CdTe-GSH Quantum Dots: understanding the bacterial toxicity of semiconductor nanoparticles Monras, JP; Collao B; Molina-Quiroz, RC; Pradenas, GA; Saona, LA; Duran-Toro, V; Ordenes-Aenishanslins, N; Venegas, FA; Loyola DE; Bravo D.; Calderon, PF; Calderon, IL; Vásquez CC; Chasteen, TG; López, DA.; Perez-Donoso, JM Article ISI SCOPUS BMC GENOMICS (2014)
Role of Salmonella Typhimurium small RNAs RyhB-1 and RyhB-2 in the oxidative stress response Calderón IL, Morales EH, Collao B, Calderón PF, Chahuán CA, Acuña LG, Gil F, Saavedra CP Article ISI (2014)
The small RNA RyhB homologs from Salmonella typhimurium participate in the response to S-nitrosoglutathione-induced stress Calderón PF, Morales EH, Acuña LG, Fuentes DN, Gil F, Porwollik S, McClelland M, Saavedra CP, Calderón IL Article ISI SCOPUS (2014)


The exosporium cysteine‐rich proteins, CdeC and CdeM, are involved in the morphogenesis of the exosporium layer and biology of Clostridium difficile spores Calderón-Romero, Paulina; Mauro Milano-Céspedes; Enzo Guerrero-Araya; Valeria Olguín-Araneda; Pablo Castro-Córdova; Fernando Gil; Daniel Paredes-Sabja ConferencePoster (2017)
Ultrastructural Variability of the Outermost Exosporium-like Layer of Clostridium difficile spores. Calderón-Romero, Paulina; Pablo Castro-Córdova; Paola Mora-Uribe; Daniel Paredes-Sabja ConferencePoster (2015)
Role of Salmonella Typhimurium small RNAs IsrE and RyhB in the nitrosative stress response Calderón-Romero, Paulina; Morales E.H; Acuña L; Collao B; Gil, F.; Saavedra, C. P.; Calderón I.L. ConferencePoster (2013)


Evaluation of the role of Salmonella Typhimurium IsrE small RNA in modulating a coupled response against nitrosative stress and iron starvation FONDECYT (11110216) Proyecto 2012-2014 Personal técnico y/o de apoyo